JPH035174B2 - - Google Patents
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- Publication number
- JPH035174B2 JPH035174B2 JP57176646A JP17664682A JPH035174B2 JP H035174 B2 JPH035174 B2 JP H035174B2 JP 57176646 A JP57176646 A JP 57176646A JP 17664682 A JP17664682 A JP 17664682A JP H035174 B2 JPH035174 B2 JP H035174B2
- Authority
- JP
- Japan
- Prior art keywords
- frequency coil
- magnetic field
- tip
- nmr
- magnetic resonance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- Instruments For Viewing The Inside Of Hollow Bodies (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Endoscopes (AREA)
Description
【発明の詳細な説明】
本発明は、生体の消化器管内表面、特に胃壁上
層部に発生する表皮ガン等を検出診断する内視鏡
に利用される核磁気共鳴信号診断装置に関する。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a nuclear magnetic resonance signal diagnostic apparatus used in an endoscope for detecting and diagnosing epidermal cancer and the like occurring on the inner surface of the gastrointestinal tract of a living body, particularly in the upper layer of the stomach wall.
従来、核磁気共鳴（NMR）現象を利用した診
断装置としては、特開昭51−127785号公報に記載
されたものが知られている。このものは、磁場発
生手段と高周波コイルとを一体にした信号検出部
を被測定部位に極めて接近して配置し、上記検出
部によつて被測定部位のNMR信号を測定するよ
うにしたものである。 BACKGROUND ART Conventionally, as a diagnostic device using nuclear magnetic resonance (NMR) phenomenon, one described in Japanese Patent Application Laid-Open No. 127785/1983 is known. In this device, a signal detection section that integrates a magnetic field generating means and a high-frequency coil is placed very close to the part to be measured, and the detection part measures the NMR signal of the part to be measured. be.
しかしながら、単に信号検出部を被測定部位に
極めて接近して配置しただけでは高解像度の
NMR信号を測定できず、0.5テスラまたは1.5テ
スラ（テスラ：磁束密度の単位、１テスラ＝
1Wb／m2＝104G［ガウス］）という強力な磁場発
生手段から発生させる必要があつた。このため、
磁場発生手段は必然的に大型なものとなり、磁場
発生手段と高周波コイルとを一体化して信号検出
部を構成した従来公報の装置においては信号検出
部の大型化が避けられず、管腔臓器への挿入が要
求される内視鏡には適用が困難であつた。 However, simply placing the signal detection unit very close to the measurement target is not enough to achieve high resolution.
Unable to measure NMR signal, 0.5 Tesla or 1.5 Tesla (Tesla: unit of magnetic flux density, 1 Tesla =
It was necessary to generate a magnetic field as strong as 1Wb/m 2 = 10 4 G [Gauss]). For this reason,
The magnetic field generating means is inevitably large, and in the device of the conventional publication in which the magnetic field generating means and the high-frequency coil were integrated to form the signal detecting section, the signal detecting section was unavoidably large, and it was difficult to reach the hollow organ. It has been difficult to apply this method to endoscopes that require the insertion of
しかも、高周波コイルの周辺部に非誘電体材料
が使用されていると高周波コイルのまわりの磁場
が乱れてしまい、正確なNMR信号を検出できな
い場合があるが、従来公報の装置のように磁場発
生手段と高周波コイルを一体化したものにあつて
は高周波コイルの周辺部に非誘電体材料が使用さ
れるので、上述した欠点を解消できない問題もあ
つた。 Furthermore, if a non-dielectric material is used around the high-frequency coil, the magnetic field around the high-frequency coil may be disturbed and accurate NMR signal detection may not be possible. In the case where the means and the high-frequency coil are integrated, a non-dielectric material is used for the periphery of the high-frequency coil, so there is a problem that the above-mentioned drawbacks cannot be overcome.
本発明は以上のような事情に基づいてなされた
ものであり、信号検出部の小型化をはかるととも
に、正確でしかも高解像度のNMR信号を測定す
ることができ、内視鏡に適用して優れた効果を奏
し得る核磁気共鳴信号診断装置を提供することを
目的とするものである。 The present invention has been made based on the above circumstances, and it is possible to miniaturize the signal detection section and measure accurate and high-resolution NMR signals, and is excellent when applied to endoscopes. It is an object of the present invention to provide a nuclear magnetic resonance signal diagnostic apparatus that can exhibit the following effects.
本発明は上記の目的を達成するために、体腔内
に挿入可能な可撓性細菅と、この可撓性細菅の先
端に設けられた高周波コイルと、誘電体材料で形
成され高周波コイルを収容する高周波コイル収容
部と、体外に設けられ生体に対して磁場を発生す
る体外磁場発生装置とを備えている。 In order to achieve the above object, the present invention includes a flexible tube that can be inserted into a body cavity, a high-frequency coil provided at the tip of the flexible tube, and a high-frequency coil made of a dielectric material. It includes a high-frequency coil accommodating section and an extracorporeal magnetic field generator that is provided outside the body and generates a magnetic field toward the living body.
以下、図面に示す実施例に基づいて本発明を詳
細に説明にする。 Hereinafter, the present invention will be described in detail based on embodiments shown in the drawings.
第１図及び第２図はいずれも本発明の一実施例
を示すもので、第１図は内視鏡先端部の構造を示
す図、第２図は全体構成を示す図である。第１図
及び第２図に示すように、内視鏡１の操作部１ａ
に接続された可撓性細管２の先端部にはレンズ６
及びイメージガイド７よりなる直視型光学系が設
けられており、イメージガイド７は可撓性細管２
中を挿通して操作部１ａに達つしている。一方、
直視型光学系の近傍には先端が、開放されかつ全
面が誘電体材料で形成された高周波コイル収容部
としての円筒部３が設けられており、この円筒部
３内には被検査部位１４に核磁気共鳴（NMR）
用の高周波を与える高周波コイル４が設けられて
いる。高周波コイル４はリード線５の一端と接続
しており、リード線５の他端は可撓性細管２中を
挿通して、その基端部まで導かれ、核磁気共鳴
（NMR）測定装置１０に接続されている。 1 and 2 both show one embodiment of the present invention, with FIG. 1 showing the structure of the distal end of the endoscope, and FIG. 2 showing the overall configuration. As shown in FIGS. 1 and 2, the operating section 1a of the endoscope 1
A lens 6 is attached to the tip of the flexible thin tube 2 connected to the
A direct viewing optical system is provided, which includes a flexible thin tube 2 and an image guide 7.
It is inserted through the inside and reaches the operating section 1a. on the other hand,
A cylindrical part 3 serving as a high-frequency coil accommodating part is provided near the direct-viewing optical system, and the tip is open and the entire surface is made of a dielectric material. nuclear magnetic resonance (NMR)
A high frequency coil 4 is provided which provides a high frequency wave for use. The high frequency coil 4 is connected to one end of a lead wire 5, and the other end of the lead wire 5 is inserted through the flexible thin tube 2 and guided to its base end, and is connected to a nuclear magnetic resonance (NMR) measuring device 10. It is connected to the.
したがつて、このような構成の本実施例を操作
する場合には、第２図に示すように被検者１３を
体外磁場発生装置としてのマグネツト１１及び１
２より形成される磁場の中に置き、可撓性細管２
の先端を被検者１３の口腔より挿入する。そし
て、例えば胃壁上層部を操作部１ａから観察光学
系にて観察する。この時、被検査部位１４に異常
部位を発見したとすると、第１図に示すように高
周波コイル４を異常部位に押し当て、NMR測定
装置１０から高周波をリード線５を介して高周波
コイル４に送り、異常部位に高周波を照射する。
そして、高周波によつて発生した異常部位の
NMR信号を高周波コイル４で検出し、NMR測
定装置１０でNMR信号を測定し、この信号によ
つて異常部位の生理的変化を観察して診断を下
す。 Therefore, when operating this embodiment having such a configuration, as shown in FIG.
The flexible tubule 2 is placed in a magnetic field formed by the flexible tube 2.
Insert the tip of the tube into the oral cavity of the subject 13. Then, for example, the upper layer of the stomach wall is observed using the observation optical system from the operating section 1a. At this time, if an abnormal part is found in the inspected part 14, the high frequency coil 4 is pressed against the abnormal part as shown in FIG. Then, the abnormal area is irradiated with high frequency waves.
Then, the abnormal area caused by high frequency is
The high frequency coil 4 detects the NMR signal, the NMR measuring device 10 measures the NMR signal, and based on this signal, physiological changes in the abnormal area are observed and a diagnosis is made.
このように本実施例では内視鏡観察時において
疑わしい部位を発見してもその場でガンか否か診
断を下すことが可能となる。 In this way, in this embodiment, even if a suspicious site is found during endoscopic observation, it is possible to diagnose on the spot whether it is cancer or not.
このように本実施例においては、体外磁場発生
装置としてのマグネツト１１及び１２と高周波コ
イル４とを別体化し、上記高周波コイル４を体腔
内に挿入可能な可撓性細菅２の先端に設け、マグ
ネツト１１及び１２を体外に設けている。そし
て、上記マグネツト１１及び１２から強力な磁場
を被検者の生体に対して発生させるとともに、可
撓性細菅２を被検者の口腔より挿入し、高周波コ
イル４を体腔内の診断部位に近接させて診断を行
つている。従つて、高周波コイル４により高解像
度のNMR信号を測定できるようになる。しか
も、高周波コイル４は誘電体材料で形成された円
筒部３内に収容されているので、誘導起電力の影
響を受けにくく、正確なNMR信号を受信でき
る。 As described above, in this embodiment, the magnets 11 and 12 as an extracorporeal magnetic field generator and the high-frequency coil 4 are separated, and the high-frequency coil 4 is provided at the tip of the flexible narrow tube 2 that can be inserted into the body cavity. , magnets 11 and 12 are provided outside the body. Then, a strong magnetic field is generated from the magnets 11 and 12 to the subject's living body, the flexible tube 2 is inserted through the subject's oral cavity, and the high-frequency coil 4 is placed at the diagnostic site in the body cavity. Diagnosis is carried out in close proximity. Therefore, the high-frequency coil 4 allows high-resolution NMR signals to be measured. Moreover, since the high frequency coil 4 is housed in the cylindrical portion 3 made of a dielectric material, it is less susceptible to the influence of induced electromotive force and can receive accurate NMR signals.
また、高周波コイル４のみを可撓性細菅２の先
端に取り付けるので信号検出部位を小型化でき
る。よつて、体腔内に挿入する場合の挿入性に優
れ、患者への負担を軽減できる。 Further, since only the high frequency coil 4 is attached to the tip of the flexible tube 2, the signal detection portion can be miniaturized. Therefore, it has excellent insertability when inserted into a body cavity, and the burden on the patient can be reduced.
次に本発明の他の実施例について第３図及び第
４図を参照して説明する。なお第３図及び第４図
中第１図と同一部分には同一符号を付し、その部
分の説明は省略する。 Next, another embodiment of the present invention will be described with reference to FIGS. 3 and 4. In FIGS. 3 and 4, the same parts as in FIG. 1 are designated by the same reference numerals, and explanations of those parts will be omitted.
前記実施例では単に被検査部位に高周波コイル
４を押し当てるだけの構成であるために表面が隆
起している部位に対しては問題が生じないが、隆
起していない部位に対してはコイル４内まで取込
むことができない。したがつて、第２実施例では
第３図に示すように、円筒部３の開放側端面に環
状弾性シール部材としてのＯリング８を取り付
け、これと反対側の非開放側端面に吸気管９を設
けた構造としている。このようにすれば、被検査
部位１４が吸気管９からの吸引力によつてコイル
内深部まで取り込むことができる。その結果、よ
り均一性の高い高周波磁場を形成することができ
るので、Ｓ／Ｎ及び検出感度が一段と向上する。 In the above-mentioned embodiment, since the configuration is such that the high-frequency coil 4 is simply pressed against the inspected area, there is no problem with areas with raised surfaces. It is not possible to take it inside. Therefore, in the second embodiment, as shown in FIG. 3, an O-ring 8 as an annular elastic seal member is attached to the open side end face of the cylindrical part 3, and an intake pipe 9 is attached to the non-open side end face on the opposite side. It has a structure with In this way, the part to be inspected 14 can be drawn deep into the coil by the suction force from the intake pipe 9. As a result, it is possible to form a high-frequency magnetic field with higher uniformity, thereby further improving the S/N and detection sensitivity.
なお上記実施例では高周波コイル４は全面が誘
電体で形成された円筒部３内に配置されていると
述べたが、第４図に示すように高周波コイル４を
中空円筒部３外周に埋設しても、上記実施例と同
様の効果を得ることができる。 In the above embodiment, it has been described that the high frequency coil 4 is placed inside the cylindrical part 3 whose entire surface is made of dielectric material, but as shown in FIG. However, the same effects as in the above embodiment can be obtained.
以上詳述したように本発明によれば、体腔内に
挿入可能な可撓性細菅と、この可撓性細菅の先端
に設けられた高周波コイルと、誘電体材料で形成
され高周波コイルを収容する高周波コイル収容部
と、体外に設けられ生体に対して磁場を発生する
体外磁場発生装置とを備えたので、信号検出部の
小型化をはかるとともに、正確でしかも高解像度
のNMR信号を測定することができ、内視鏡に適
用して優れた効果を奏し得る核磁気共鳴信号診断
装置を提供できる。 As detailed above, according to the present invention, there is a flexible tube that can be inserted into a body cavity, a high-frequency coil provided at the tip of the flexible tube, and a high-frequency coil formed of a dielectric material. Equipped with a high-frequency coil accommodating section and an extracorporeal magnetic field generator that is installed outside the body and generates a magnetic field toward the living body, the signal detection section can be miniaturized and accurate and high-resolution NMR signals can be measured. Therefore, it is possible to provide a nuclear magnetic resonance signal diagnostic apparatus that can be applied to an endoscope and exhibit excellent effects.
第１図は本発明の一実施例である内視鏡先端部
の構造を示す断面図、第２図は同実施例の全体構
成を示す構成図、第３図及び第４図は本発明の他
の実施例の内視鏡先端部を示す断面図である。
１……内視鏡、２……可撓性細管、３……円筒
部、４……高周波コイル、５……リード線、６…
…レンズ、７……イメージガイド、８……Ｏリン
グ、９……吸気管、１０……NMR測定装置、１
１，１２……マグネツト。
FIG. 1 is a cross-sectional view showing the structure of the distal end of an endoscope according to an embodiment of the present invention, FIG. 2 is a configuration diagram showing the overall configuration of the same embodiment, and FIGS. 3 and 4 are FIG. 7 is a sectional view showing a distal end portion of an endoscope according to another embodiment. DESCRIPTION OF SYMBOLS 1... Endoscope, 2... Flexible thin tube, 3... Cylindrical part, 4... High frequency coil, 5... Lead wire, 6...
...Lens, 7...Image guide, 8...O ring, 9...Intake pipe, 10...NMR measuring device, 1
1,12...Magnet.
Claims (1)
ルと、 誘電体材料で形成され前記高周波コイルを収容
する高周波コイル収容部と、 体外に設けられ生体に対して磁場を発生する体
外磁場発生装置と、 を具備したことを特徴とする核磁気共鳴信号診断
装置。 ２ 前記可撓性細菅は、その先端に観察手段を有
する内視鏡であることを特徴とする特許請求の範
囲第１項記載の核磁気共鳴信号診断装置。[Scope of Claims] 1. A flexible narrow tube that can be inserted into a body cavity, a high-frequency coil provided at the tip of the flexible narrow tube, and a high-frequency coil formed of a dielectric material and accommodating the high-frequency coil. A nuclear magnetic resonance signal diagnostic device comprising: a housing section; and an extracorporeal magnetic field generator that is provided outside the body and generates a magnetic field toward a living body. 2. The nuclear magnetic resonance signal diagnostic apparatus according to claim 1, wherein the flexible narrow tube is an endoscope having observation means at its tip.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57176646A JPS5967929A (en) | 1982-10-07 | 1982-10-07 | Endoscope apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57176646A JPS5967929A (en) | 1982-10-07 | 1982-10-07 | Endoscope apparatus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5967929A JPS5967929A (en) | 1984-04-17 |
| JPH035174B2 true JPH035174B2 (en) | 1991-01-24 |
Family
ID=16017215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57176646A Granted JPS5967929A (en) | 1982-10-07 | 1982-10-07 | Endoscope apparatus |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5967929A (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4572198A (en) * | 1984-06-18 | 1986-02-25 | Varian Associates, Inc. | Catheter for use with NMR imaging systems |
| JPH0710281B2 (en) * | 1986-09-19 | 1995-02-08 | 三菱電機株式会社 | Laser therapy equipment |
| JP2575398B2 (en) * | 1987-08-10 | 1997-01-22 | オリンパス光学工業株式会社 | Antenna device for NMR measurement |
| JPS63270037A (en) * | 1987-04-28 | 1988-11-08 | Olympus Optical Co Ltd | Endoscope |
| JP2615042B2 (en) * | 1987-04-27 | 1997-05-28 | オリンパス光学工業株式会社 | Endoscope for strong magnetic field |
| JP2575395B2 (en) * | 1987-07-15 | 1997-01-22 | オリンパス光学工業株式会社 | Antenna device for NMR measurement |
| JPS63270039A (en) * | 1987-04-28 | 1988-11-08 | Olympus Optical Co Ltd | Endoscope |
| JPS6443242A (en) * | 1987-08-10 | 1989-02-15 | Olympus Optical Co | Endoscope |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51127785A (en) * | 1975-04-30 | 1976-11-08 | Hokkaido Daigaku | Measuring method of information around the surface of the substances t o be measured applying the nucleus magnet resonance phenomenon |
-
1982
- 1982-10-07 JP JP57176646A patent/JPS5967929A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5967929A (en) | 1984-04-17 |
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