JPH0433417B2 - - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION (Field of Industrial Application) The present invention relates to a laboratory animal breeding apparatus for raising laboratory animals such as guinea pigs, mice, and rats in aseptic or predetermined sterile conditions.

(Prior Art) Conventionally, this type of device has been installed as a semi-permanent facility on the ground. For this reason, there is a risk that the environment in the surrounding area will be deteriorated due to pollution and filth discharged by laboratory animals, and even if treatment facilities are installed, it is difficult to prevent the deterioration of the water quality of rivers in the surrounding area and the occurrence of bad odors. In some cases, it is difficult to obtain the consent of local residents when establishing a semi-permanent facility. The problem is that it takes a long time to make a round trip, which is inconvenient.

As a solution to the above-mentioned difficulties,
There is an idea described in Publication No. 18943. This system has an animal rearing laboratory and an experimental front room on a trolley, and according to this system, it can be installed at a desired location only during the experiment period, and after that period, it can be easily removed from that location. Because it is possible to do so, it does not cause deterioration of the surrounding environment.

However, since there is no equipment to remove bacteria that adhere to the bodies and clothes of researchers and others who enter both rooms, there is a risk that bacteria may be brought into the rooms and contaminate the experimental animals. It is difficult to raise them under sterile conditions or in designated sterile conditions and to perform surgery, making it difficult to obtain desired research results.

SUMMARY OF THE INVENTION Therefore, an object of the present invention is to provide an experimental animal breeding apparatus that eliminates the above-mentioned drawbacks.

(Surgery to Solve the Problems) The structure of the present invention for achieving the above object will be explained using FIGS. 1 to 4 corresponding to the embodiments. Alternatively, partition walls 7 may be installed in a sealed box 4 in the form of a cargo handling container that is integrally connected to an automobile 23 and movable.
and a laboratory animal breeding room A, a laboratory animal operating room B, a changing room C, a shower room D, a sterile clothes changing room E, and a passage H connecting these through the hermetic door 8, which are separated by a hermetic door 8, A clothing pass box 10 communicating with both rooms B and C is provided on the partition wall 7 that partitions the dressing room C and the laboratory animal operating room B, and a clothing pass box 10 is provided at both end openings of the dressing room side so as to be openable and closable. The gate 10a and the operating room side gate 10b are constructed so that when one of them is open, the other is closed, and a germicidal lamp is disposed inside the pass box 10. .

(Embodiment) FIGS. 1 to 3 show a laboratory animal breeding apparatus 1 as an embodiment of the present invention, in which a closed box shaped like a cargo handling container is placed on a base 3 supported by outriggers 2. 4, an inlet 5 was formed in the front wall of the sealed box, an outlet 6 was formed in the rear wall, and the sealed box 4 was partitioned by a partition wall 7 and a sealed door 8. An animal breeding room A, a laboratory animal operating room B, a changing room C, a shower room D, a sterile clothing changing room E, a dressing room F, a laboratory animal receiving room G, and a passage H connecting these through the sealed door 8 are provided. ing. In order to maintain the sterile condition inside the sealed box 4, sealed doors 8 are also provided at the entrance 5, exit 6, etc.

In FIGS. 1 and 2, reference numeral 10 denotes a clothing pass box provided on the partition wall 7 that partitions the laboratory animal operating room B and the changing room C, and the changing room side gate 10a of the pass box 10 is opened. When clothes are placed in the pass box 10, the clothes are sterilized by a germicidal lamp (not shown) in the pass box 10, and the operating room side gate 10b is opened to ensure a sterile state. You can now take out your clothes. Note that both the gates 10a and 10b are configured so that when one of them is opened, the other one is always closed.
Bacteria are prevented from entering the experimental animal operating room B through the pass box 10. Reference numeral 11 denotes a pass box for laboratory animals installed in the partition wall 7 that separates the laboratory animal operation room B and the laboratory animal rearing room A, and has the same structure as the clothing pass box 10. Experimental animals can be transferred directly between the two without passing through passage H.

Furthermore, in FIGS. 1 and 2, 12 is a breeding shelf that supports the breeding cage 13 for experimental animals;
Reference numeral 4 denotes an air conditioner disposed on a ceiling plate 15, etc., and 16 is a machine room for operating the air conditioner 14, etc., which is placed on the base 3 outside the closed box 4. 17 is a storage tank for sewage, filth, etc.;
It is connected to drain pipes with on-off valves 18 in the rearing room A, operating room B, etc. via a drain hose 17a. Note that when the tank 17 becomes full with sewage, etc., the tank 17 is replaced with a new one by a treatment company, and the tank 17 containing the sewage, etc. is transported to a treatment plant and treated. Therefore, there is no risk of deterioration of the water quality of surrounding rivers or generation of foul odors. 19 is a ladder provided at the entrance 5 and the exit 6. Furthermore, as is well known, the outriggers 2 can be retracted inward (see phantom lines in FIG. 3). 21 is a water tank.

The experimental animal breeding apparatus 1 described above is used in the following manner. First, when researchers enter the experimental animal breeding room A and the experimental animal surgery room B, they enter the changing room C through the entrance 5, take off their clothes, wash their bodies in the shower room D, and put on sterile clothes. The patient cannot enter the breeding room A and the operating room B until after changing into sterile clothes in the changing room E. Therefore, there is no risk of bacteria entering the breeding room A and operating room B, and both rooms A and B can be kept in a sterile state that complies with the GLP safety standards required for this type of equipment. . The clothes taken off in the changing room C are sealed in a synthetic resin bag and then placed in the clothes pass box 10.

Next, the researcher who has entered the operating room B receives the experimental animal from the breeding room A via the experimental animal pass box 11, and returns the experimental animal to the breeding room A via the pass box 11 after the surgery.

When a researcher in the operating room B leaves the room, he/she takes out the clothes in the clothing pass box 10, passes through the laboratory animal breeding room A, enters the dressing room F, takes off the sterile clothes, and puts on the above clothes. All you have to do is put it on and exit from the exit 6 to the closed box 4. In this case, if the patient exits through the entrance 5, there is a risk that bacteria may invade the breeding room A and the operating room B, so it is preferable to exit through the exit 6.

When bringing a laboratory animal into the laboratory animal breeding room A, the animal breeder should bring the laboratory animal in a sterile or sterile state as indicated by the dashed-dotted line through exit 6 into the laboratory animal receiving room G.
The experimental animals are inspected in the receiving room G, and only experimental animals that meet the prescribed conditions are received.

The above experimental animal breeding apparatus 1 is transported in the following manner,
Can be installed. First, when transporting
As shown in FIG. 4a, the outriggers 2 are loaded on the loading platform of Example 23 and transported with the legs of the outriggers 2 retracted. When installing the device next, as shown in FIG.
All you have to do is separate it from the

Moreover, when the breeding apparatus 1 is to be removed, the procedure may be reversed to that described above.

(Effects of the Invention) According to the present invention, when a researcher enters a laboratory animal breeding room or a laboratory animal operating room, he or she must first take off his clothes in a changing room and put them in a clothes pass box. Since sterilization is carried out using a sterilizing lamp inside the pass box, the body is washed in the shower room, and sterile clothes are put on in the sterile clothes changing room, there is no risk of bacteria entering the breeding room and operating room. , experimental animals can be kept in sterile conditions or in predetermined sterile conditions, and can be operated on, ensuring that the desired research results can be obtained.

Furthermore, since it can be installed at a desired location only during the experiment period and then easily removed from that location after that period, the surrounding environment will not be degraded.

[Brief explanation of drawings]

Fig. 1 is a horizontal cross-sectional view of a laboratory animal breeding apparatus according to an embodiment of the present invention, Fig. 2 is a vertical cross-sectional view of the same, Fig. 3 is a cross-sectional view of the same, and Figs. FIG. 3 is a schematic explanatory diagram showing an installation procedure. 1... Experimental animal breeding equipment, 4... Sealed box, 7... Partition wall, 8... Sealed door, 10...
Clothes pass box, 10a...Dressing room side gate, 10b...Operating room side gate, 23...Car, A...Laboratory animal breeding room, B...Laboratory animal operation room, C...Dressing room, D... Shower room, E...Sterile clothes changing room, H...Aisle.

Claims (1)

[Claims] 1 A laboratory animal rearing room, a laboratory animal operating room, a changing room, which are separated from each other by partition walls and sealed doors, in a cargo container-like closed box that can be moved by being loaded onto a car or integrally connected to a car.
A shower room, a sterile clothing changing room, and a passage connecting these through the sealed door are provided, and a clothing pass box communicating with both rooms is provided on the partition wall separating the changing room and the laboratory animal operating room, and the pass box A dressing room side gate and an operating room side gate are provided at both end openings so as to be openable and closable, and when one of them is open, the other is closed, and a germicidal lamp is arranged in the pass box. Experimental animal breeding equipment.