JPH0456806B2 - - Google Patents
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- Publication number
- JPH0456806B2 JPH0456806B2 JP60174735A JP17473585A JPH0456806B2 JP H0456806 B2 JPH0456806 B2 JP H0456806B2 JP 60174735 A JP60174735 A JP 60174735A JP 17473585 A JP17473585 A JP 17473585A JP H0456806 B2 JPH0456806 B2 JP H0456806B2
- Authority
- JP
- Japan
- Prior art keywords
- herbal medicine
- germ
- chinese herbal
- koji mold
- young
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- Medicines Containing Plant Substances (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Description
ａ 産業上の利用分野
本発明は現代の難病と言われている疾患、とく
に高度の冷え症を含むレイノー氏病、悪性関節リ
ユーマチ、ベーチエツト病などの疾患を治療する
のに有効な漢方薬に関する。
ｂ 従来の技術
従来、漢方薬としては朝鮮人参等の所謂一般に
知られている生薬を粉末にしたものや煎じ薬が知
られていた。
一方健康維持のためあるいは疾患と呼ぶ程では
ない病気を治療したという要望から、各種ビタミ
ン剤や健康食品が多数市販されている。
ｃ 発明が解決しようとする問題点
しかし、一般に漢方薬は副作用が少ないという
長所はあるが、効果に劣るという欠点があり、特
に所謂現代の難病と称される高度の冷え症を含む
レイノー氏病、悪性関節リユーマチ、ベーチエツ
ト病あるいは皮膚のシミ、ソバカスといつた疾患
には多くの一般の医薬品と共にほとんど効果がな
かつた。特に、一般の合成された医薬品で難病に
使用されているものは、副作用が強く、その割り
に効果に乏しく、長期使用を必要とする難病の治
療には大きな問題を投げかけていた。
また、各種ビタミン剤、健康食品も健康を維持
するのにある程度は薬理効果があるが、これら難
病の治療には程遠い存在であつた。
ｄ 問題点を解決するための手段
本発明者は、これらの難病に有効で副作用の少
ない漢方薬を求めて鋭意研究した結果、ごく普通
にヒトが食している穀類、野菜等を特殊処理し、
ある割合に配合することにより目的を達成できる
ことを見出し、本発明を完成した。
その要旨は、こうじかび、胚芽および大麦の若
葉からなる漢方薬（本発明１）であり、また、こ
うじかび、胚芽、大麦の若葉および緑茶からなる
漢方薬（本発明２）であり、また、こうじかび、
胚芽、大麦の若葉、緑茶、玄米およびごまからな
る漢方薬（本発明３）であり、また、こうじか
び、胚芽、緑茶、玄米、ごま、大麦の若葉、大根
の若葉および菜種子菜からなる漢方薬（本発明
４）であり、またこうじかび、胚芽、大麦の若
葉、玄米、ごま、大根の若葉および菜種子菜から
なる漢方薬（本発明５）にある。
配合される原料について説明する。
こうじかびは酒の醸造等に使用される所謂こう
じかびでよく、胚芽は玄米の胚芽である。大麦の
若葉は、大麦の種子を播種し発芽してから穂が出
る前に採取したものがよい。緑茶は日常ヒトが飲
用に供する乾燥した緑茶でよい。ごまは一般のご
まであり黒ごま、白ごまを問わない。玄米は精米
する前のもみがらのみを除去したものでよい。大
根の若葉は播種し発芽して10〜20cmに生育後採取
したものが使われる。菜種子菜は一般に菜種子菜
として市販されているものが使われる。
次に本発明の漢方薬の製造方法について順次述
べる。
本発明１は、60〜80℃でこげないように加熱し
たのちすり潰した胚芽と、すり潰したこうじかび
とを混合し、約32℃で24時間インクベート（養
生）したものに、ジユーサーで細かく砕き乾燥し
た大麦の若葉粉末を混合し、再度32℃で24時間イ
ンクベート（養生）したのち、−５℃で約30分間
温風を吹き込みながら冷凍乾燥し、さらに30〜35
℃で30分〜１時間乾燥したのち、室温で３日間養
生すれば得られる。
本発明２は、本発明１において、こうじかびと
胚芽に、大麦の若葉粉末を混合する工程で緑茶粉
末を一緒に混合すれば得られる。
本発明３は次の通りである。
胚芽、玄米およびごまを各々単独に60〜80℃で
こげないように加熱したのち、それぞれ別々にす
り潰す。ごまは絞つてごま油を抽出する。また、
こうじかびを単独ですり潰しておく。
すり潰したこうじかび、胚芽および玄米を混合
し、約32℃で24時間インクベート（養生）したも
のに、緑茶粉末、ジユーサーで細かく砕き乾燥し
た大麦の若葉粉末、ごま油および少量のオリーブ
油を添加混合し、再度約32℃で24時間インクベー
ト（養生）したのち、−５℃で約30分間温風を吹
き込みながら冷凍乾燥し、さらに30〜35℃で30分
〜１時間乾燥したのち、室温で３日間養生すれば
得られる。オリーブ油は混合を良くするためであ
り添加しなくてもよい。
本発明４は以下の通りである。
胚芽、玄米およびごまを各々単独に60〜80℃で
こげないように加熱したのち、それぞれ別々にす
り潰す。ごまは絞つてごま油を抽出する。また、
こうじかびを単独ですり潰しておく。すり潰した
こうじかび、胚芽および玄米を混合し、約32℃で
24時間インクベート（養生）したものに、緑茶粉
末、ジユーサーで細かく砕き乾燥した大麦の若葉
粉末、大根の若葉粉末、菜種子菜粉末、ごま油お
よび少量のオリーブ油を添加混合し、再度約32℃
で24時間インクベート（養生）したのち、−５℃
で約30分間温風を吹き込みながら冷凍乾燥し、さ
らに30〜35℃で30分〜１時間乾燥したのち、室温
で３日間養生すれば得られる。オリーブ油は混合
を良くするためであり添加しなくてもよい。
本発明５は本発明４の工程で緑茶粉末を配合し
たものである。
次に原料の配合割合につき説明する。ただし以
下に示す配合割合は目安であり、これらの配合割
合を外れても薬理効果がなくなる訳ではない。
本発明１〜５の全てにおいて、こうじかびと胚
芽（加熱処理後の状態）の割合は重量で約１：５
である。
本発明１の配合において、大麦の若葉は乾燥物
重量でこうじかびの約200倍配合する。
本発明２の配合においては、本発明１に緑茶粉
末を、こうじかびの約25倍配合する。
本発明３の配合において、こうじかびに対し、
玄米粉末は約90重量倍、大麦の若葉粉末は乾燥重
量で約70倍、緑茶粉末は約20重量倍、ごま油約15
重量倍である。
本発明４の配合においては、こうじかびに対
し、玄米粉末は約80重量倍、大麦の若葉粉末は乾
燥重量で約40倍、大麦の若葉粉末は乾燥重量で約
25重量倍、菜種子菜粉末は乾燥重量で約20重量
倍、緑茶粉末は約20重量倍、ごま油約15重量倍で
ある。
本発明５は本発明４の緑茶粉末を除いた配合で
ある。
本発明の漢方薬は、緑色でフレーク状をしてい
るが、これを錠剤にしたり顆粒、棒状等にしもよ
い。
服用する場合、普通１日当り約10ｇであるが、
疾患によつて適宜変えてもよい。服用回数は１日
３回に分けるのが良いが、それ以上に分けてもよ
い。
本発明の漢方薬は、主として天然の植物や種子
より成る。これら天然の植物や種子は、自然の中
で一日中紫外線の活性酵素に晒されており、この
活性酵素の細胞障害作用に打ち勝つて繁殖生存し
ている。このことから、これら天然の植物、種子
（胚芽・大麦・玄米・大根葉・緑茶・菜種子菜）
には強力な活性酵素除去作用がある。
本漢方薬の基本的な薬効は、活性酵素に対する
影響力、即ち抗活性酵素作用、抗酸化作用或いは
Superoxide dismutase（SOD）活性にある。
それを調べるために、活性酵素が最初に産生さ
れるSuperoxide（0- 2）を実験的に試験管中で
xanthine0.1nmol／とxanthine
oxide0.0.006U／mlを添加して産出しておき、こ
れにferricytochrome C16.5μmol／を加え、生
産される0- 2量を測定しておき、別の試験管で同様
の条件で同量の0- 2を生産した中へ、本漢方薬の
therapeutic dose（生体換算量）1.6mg／mlの×1/
１０、×１、×10を別に添加し、0- 2が減少するその減
少度を測定した。その結果、本漢方薬の抗酸化
能、即ちSOD活性が顕著であることが判明した。
本発明の漢方薬は、ヒトが食している天然の植
物や種子を用いるので、その毒性は全くない。
ｅ 作用
本発明の漢方薬は、上述したように従来のビタ
ミン剤を有している公知の作用効果を期待したも
のではなく、低分子の抗酸化剤（フラノボイド
等）による活性酸素除去作用を期待したものであ
る。しかし、本発明の効果は、漢方薬に配合され
ている緑茶、ごま、その他に含有されているフラ
ノボイドやビタミンB2，Ｃ，Ａそれぞれの単独
の効果ではない。植物中には自然の形でフライボ
イドやビタミンそれぞれが重合しあつて存在して
いて、それぞれの有している活性酸素除去用が充
分発揮できないでいるが、本発明は、こうじかび
の存在のもとにそれらの重合を解き、それぞれを
を自由に活性化させて、活性酸素除去作用を遥か
に強力させることに成功したものである。また、
それぞれの原料を最適な配合に調整することによ
り、この活性酸素除去作用をさらに倍加させると
言う相乗効果を引き出すことにも成功したもので
ある。従つて個々の原料に含まれる成分をそれぞ
れ単独に抽出して、本発明に見合う量服用しても
本発明による効果は期待できない。
ｆ 実施例
実施例 １
約70℃でこげないように加熱したのちすり潰し
た胚芽250ｇとこうじかび50ｇとを混合し、32℃
で24時間インクベートした。これにジユーサーで
細かく砕き乾燥した大麦の若葉粉末9.7Kgを混合
し、再度32℃で24時間インクベートしたのち、−
５℃で約30分間温風を吹き込みながら冷凍乾燥
し、さらに32℃で約30分間乾燥したのち、室温で
３日間養生し粉末状の漢方薬を得た。
得られた漢方薬を１日３回、１回３ｇ、期間３
週間、冷え症の患者12人に服用させたところ８人
に有効であつた。
またレイノー氏病の患者４人に同様に服用させ
たところ２人に有効であつた。
実施例 ２
約70℃でこげないように加熱したのちすり潰し
た胚芽250ｇと、こうじかび50ｇとを混合し、32
℃で24時間インクベートした。これに、ジユーサ
ーで細かく砕き乾燥した大麦の若葉粉末8.5Kgと
緑茶粉末1.2Kgを混合し、再度32℃で24時間イン
クベートしたのち、−５℃で約30分間温風を吹き
込みながら冷凍乾燥し、さらに32℃で約30分間乾
燥したのち、室温で３日間養生し漢方薬を得た。
得られた漢方薬を１日３回、１回３ｇ患者に服
用させたところ、第１表に示す通りの効果が得ら
れた。
a. Field of Industrial Application The present invention relates to a Chinese herbal medicine effective for treating diseases that are said to be incurable in modern times, particularly Raynaud's disease including severe sensitivity to cold, malignant rheumatoid arthritis, and Behchiet's disease. b. Prior Art Traditionally, as herbal medicines, powders and decoctions of commonly known crude drugs such as Korean ginseng have been known. On the other hand, a large number of various vitamin supplements and health foods are on the market for the purpose of maintaining health or for treating illnesses that are not so serious as to be called diseases. c Problems to be solved by the invention However, although Chinese herbal medicines generally have the advantage of having few side effects, they also have the disadvantage of being less effective, especially for Raynaud's disease, which includes severe cold sensitivity, which is called a modern incurable disease, and malignant disease. It had little effect on diseases such as rheumatoid arthritis, Behtschett's disease, or skin spots and freckles, along with many over-the-counter medicines. In particular, commonly synthesized drugs used to treat incurable diseases have strong side effects and are relatively ineffective, posing major problems in the treatment of incurable diseases that require long-term use. In addition, various vitamin supplements and health foods have pharmacological effects to some extent in maintaining health, but they are far from being effective in treating these intractable diseases. d. Means for Solving the Problems As a result of intensive research in search of Chinese herbal medicines that are effective for these incurable diseases and have few side effects, the present inventor has specially processed grains, vegetables, etc. that are commonly eaten by humans.
They discovered that the objective could be achieved by blending them in a certain proportion, and completed the present invention. The gist is a Chinese herbal medicine consisting of Koji mold, germ, and young barley leaves (present invention 1), and a Chinese herbal medicine consisting of Koji mold, germ, young barley leaves, and green tea (present invention 2); ,
A Chinese herbal medicine (present invention 3) consisting of germ, young barley leaves, green tea, brown rice, and sesame, and a Chinese herbal medicine (invention 3) consisting of Koji mold, germ, green tea, brown rice, sesame, young barley leaves, young radish leaves, and rapeseed rape. Invention 4) and Chinese herbal medicine (Invention 5) consisting of Koji mold, germ, young barley leaves, brown rice, sesame, young radish leaves, and rapeseed rape. The raw materials to be blended will be explained. The koji mold may be the so-called koji mold used for brewing sake, etc., and the germ is the germ of brown rice. Young barley leaves are preferably collected after sowing barley seeds and before they germinate and before ears appear. The green tea may be dried green tea that people drink on a daily basis. Sesame can be regular sesame, black sesame or white sesame. Brown rice can be made by removing only the rice husks before polishing. Young radish leaves are sown, germinated, and harvested after they grow to a height of 10 to 20 cm. As rapeseed vegetables, those commercially available as rapeseed vegetables are generally used. Next, the method for producing the Chinese herbal medicine of the present invention will be sequentially described. Invention 1 is a mixture of germs that have been heated at 60 to 80 degrees Celsius without burning and then ground and ground Koji mold, incubated (cured) at about 32 degrees Celsius for 24 hours, and then finely crushed with a juicer. After mixing the dried young barley leaf powder and incubating (curing) it again at 32℃ for 24 hours, freeze-dry it at -5℃ for about 30 minutes while blowing warm air, and then incubate for 30 to 35 minutes.
It can be obtained by drying at ℃ for 30 minutes to 1 hour and then curing at room temperature for 3 days. Present invention 2 can be obtained by mixing green tea powder with Koji mold and germ in the step of mixing barley young leaf powder in the present invention 1. The third invention is as follows. The germ, brown rice, and sesame are individually heated at 60 to 80°C without burning, and then ground separately. Squeeze the sesame seeds and extract the sesame oil. Also,
Grind the koji mold separately. Ground Koji mold, germ, and brown rice are mixed and incubated (cured) for 24 hours at approximately 32℃, and green tea powder, powdered young barley leaves finely ground and dried using a juicer, sesame oil, and a small amount of olive oil are added and mixed. After incubating (curing) again at about 32℃ for 24 hours, freeze-drying at -5℃ for about 30 minutes while blowing warm air, then drying at 30-35℃ for 30 minutes to 1 hour, and then drying at room temperature for 3 hours. You can get it by cultivating it for several days. Olive oil is used to improve mixing and does not need to be added. Present invention 4 is as follows. The germ, brown rice, and sesame are individually heated at 60 to 80°C without burning, and then ground separately. Squeeze the sesame seeds and extract the sesame oil. Also,
Grind the koji mold separately. Mix ground Koji mold, germ and brown rice and heat at approximately 32℃.
After incubation (curing) for 24 hours, green tea powder, powdered young barley leaves finely ground and dried using a juicer, powdered young radish leaves, rapeseed powder, sesame oil, and a small amount of olive oil are added and mixed, and the mixture is heated again to about 32℃.
After incubating (curing) for 24 hours at -5℃
It can be obtained by freeze-drying it for about 30 minutes while blowing hot air, then drying it for another 30 minutes to 1 hour at 30 to 35 degrees Celsius, and then curing it at room temperature for 3 days. Olive oil is used to improve mixing and does not need to be added. Present invention 5 is a product in which green tea powder is blended in the process of present invention 4. Next, the blending ratio of raw materials will be explained. However, the blending ratios shown below are only a guideline, and deviations from these blending ratios do not mean that the pharmacological effects will be lost. In all of inventions 1 to 5, the ratio of Koji mold and germ (state after heat treatment) is approximately 1:5 by weight.
It is. In the formulation of the present invention 1, the dry weight of young barley leaves is about 200 times that of Koji mold. In the formulation of Invention 2, about 25 times more green tea powder is added to Invention 1 than Koji mold. In the formulation of present invention 3, against Koji mold,
Brown rice powder is about 90 times the dry weight, barley young leaf powder is about 70 times the dry weight, green tea powder is about 20 times the dry weight, and sesame oil is about 15 times the dry weight.
It is twice the weight. In the formulation of present invention 4, the brown rice powder is about 80 times the dry weight of Koji mold, the young barley leaf powder is about 40 times the dry weight, and the young barley leaf powder is about 40 times the dry weight of Koji mold.
25 times the dry weight of rapeseed rape powder, about 20 times the dry weight of green tea powder, and about 15 times the weight of sesame oil. Invention 5 is a formulation of Invention 4 except for the green tea powder. The herbal medicine of the present invention is green and flaky, but it may be made into tablets, granules, rods, etc. When taking it, it is usually about 10g per day,
It may be changed as appropriate depending on the disease. It is best to divide the dosage into 3 times a day, but it may be taken more than 3 times a day. The herbal medicine of the present invention mainly consists of natural plants and seeds. These natural plants and seeds are exposed to active enzymes from ultraviolet rays all day long in nature, and survive and reproduce by overcoming the cytotoxic effects of these active enzymes. From this, these natural plants and seeds (germ, barley, brown rice, radish leaves, green tea, rapeseed vegetables)
has a strong active enzyme removal effect. The basic medicinal effects of this Chinese herbal medicine are its influence on active enzymes, i.e., anti-active enzyme action, antioxidant action, and
In superoxide dismutase (SOD) activity. To find out, the active enzyme was first produced using superoxide (0 - 2 ) in a test tube.
xanthine0.1nmol/and xanthine
Add 0.0.006U/ml of oxide, add 16.5μmol/ferricytochrome C, measure the amount of 0 - 2 produced, and add the same amount under the same conditions in another test tube. This Chinese herbal medicine was used to produce 0 - 2 .
Therapeutic dose (bio equivalent dose) 1.6 mg/ml x 1/
10, ×1, and ×10 were added separately, and the degree of decrease in 0 - 2 was measured. As a result, it was found that this Chinese herbal medicine has remarkable antioxidant ability, that is, SOD activity. Since the Chinese herbal medicine of the present invention uses natural plants and seeds that are consumed by humans, there is no toxicity at all. e Action As mentioned above, the Chinese herbal medicine of the present invention is not expected to have the known action and effect of conventional vitamin preparations, but is expected to have the active oxygen removal action of a low-molecular antioxidant (furanoboid, etc.). It is something. However, the effect of the present invention is not the effect of each of the furanoboid and vitamins B 2 , C, and A contained in green tea, sesame, and other herbal medicines alone. In plants, fly voids and vitamins naturally exist in polymerized form, and their ability to remove active oxygen cannot be fully utilized. By undoing their polymerization and freely activating each of them, we succeeded in making the active oxygen removal effect much stronger. Also,
By adjusting each raw material to an optimal composition, we have succeeded in bringing out a synergistic effect that further doubles this active oxygen removal effect. Therefore, the effects of the present invention cannot be expected even if the components contained in each raw material are individually extracted and administered in amounts commensurate with the present invention. f Examples Example 1 Mix 250 g of germ that was heated at about 70°C without burning and then ground, and 50 g of Koji mold, and heated to 32°C.
Incubated for 24 hours. This was mixed with 9.7 kg of powdered young barley leaves that had been finely ground and dried using a juicer, and after incubating again at 32°C for 24 hours, -
The mixture was freeze-dried at 5°C for about 30 minutes while blowing warm air, then dried at 32°C for about 30 minutes, and then cured at room temperature for 3 days to obtain a powdered herbal medicine. Take the obtained herbal medicine three times a day, 3g per time, period 3
When given to 12 patients with cold sensitivity for a week, it was effective in 8 patients. When four patients with Raynaud's disease were given the same drug, it was effective in two. Example 2 250 g of germ that was heated at about 70°C without burning and then ground was mixed with 50 g of Koji mold.
Incubate for 24 hours at °C. This was mixed with 8.5 kg of young barley powder, which had been finely crushed and dried using a juicer, and 1.2 kg of green tea powder. After incubation at 32°C for 24 hours, the mixture was freeze-dried at -5°C for about 30 minutes while blowing hot air. After further drying at 32°C for about 30 minutes, the mixture was cured at room temperature for 3 days to obtain a Chinese herbal medicine. When the obtained Chinese herbal medicine was administered to a patient at a dose of 3 g three times a day, the effects shown in Table 1 were obtained.
【表】
注：第１表〜第４表において、〓効果のあつ
た人〓とは、症状が著しく好転した人をい
う。
実施例 ３
約70℃でこげないように加熱したのちすり潰し
た胚芽250ｇと、玄米4.5Kgおよびこうじかび50ｇ
を混合し、32℃で24時間インクベートした。これ
に、ジユーサーで細かく砕き乾燥した大麦の若葉
粉末3.5Kgと緑茶粉末１Kgに、ごまを約70℃でこ
げないように加熱したのちすり潰して絞つたごま
油700ｇと、少量のオリーブ油を添加混合し、再
度32℃で24時間インクベートしたのち、−５℃で
約30分間温風を送り込みながら冷凍乾燥し、さら
に32℃で約30分間乾燥したのち、室温で３日間養
生し漢方薬を得た。
得られた漢方薬を１日３回、１回３ｇを患者に
服用させ、第２表の結果を得た。[Table] Note: In Tables 1 to 4, "those who responded well" refers to those whose symptoms improved significantly.
Example 3 250g of germ that was heated to about 70℃ without burning and then ground, 4.5Kg of brown rice, and 50g of Koji mold
were mixed and incubated at 32°C for 24 hours. To this, 3.5 kg of young barley powder that has been finely crushed and dried using a juicer, 1 kg of green tea powder, 700 g of sesame oil that has been heated to about 70℃ without burning, then ground and squeezed, and a small amount of olive oil are added and mixed. After incubating again at 32°C for 24 hours, it was freeze-dried at -5°C for about 30 minutes while blowing warm air, then dried at 32°C for about 30 minutes, and then cured at room temperature for 3 days to obtain a Chinese herbal medicine. The obtained Chinese herbal medicine was administered to a patient at a dose of 3 g three times a day, and the results shown in Table 2 were obtained.
【表】
実施例 ４
約70℃でこげないように加熱したのちすり潰し
た胚芽500ｇと、玄米7.6Kgおよびこうじかび100
ｇを混合し、32℃で24時間インクベートした。こ
れに、ジユーサーで細かく砕き乾燥した大麦の若
葉粉末４Kg、大限の若葉粉末2.4Kg、菜種子菜粉
末２Kgおよび緑茶粉末２Kgと、ごまを約70℃でこ
げないように加熱したのちすり潰して絞つたごま
油1.4Kgと、少量のオリーブ油とを混合し、再度
32℃で24時間インクベートしたのち、−５℃で約
30分間温風を込り込みながら冷凍乾燥し、さらに
32℃で約30分間乾燥したのち、室温で３日間養生
し漢方薬を得た。
得られた漢方薬を１日３回、１回３ｇを患者に
服用させ、第３表の結果を得た。[Table] Example 4 500g of germ that was heated to about 70℃ without burning and then ground, 7.6Kg of brown rice, and 100 koji mold
g were mixed and incubated at 32°C for 24 hours. To this, 4 kg of barley young leaf powder finely crushed and dried using a juicer, 2.4 kg of Daigai young leaf powder, 2 kg of rapeseed powder, and 2 kg of green tea powder, and sesame seeds were heated at about 70 degrees Celsius without burning, then ground and squeezed. Mix 1.4Kg of sesame oil and a small amount of olive oil and try again.
After incubating at 32℃ for 24 hours, at -5℃
Freeze-dry with hot air for 30 minutes, then
After drying at 32°C for about 30 minutes, it was cured at room temperature for 3 days to obtain a Chinese herbal medicine. The obtained Chinese herbal medicine was administered to a patient at a dose of 3 g three times a day, and the results shown in Table 3 were obtained.
【表】
実施例 ５
約70℃でこげないように加熱したのちすり潰し
た胚芽500ｇと、玄米7.6Kgおよびこうじかび100
ｇを混合し、32℃で24時間インクベートした。
これに、ジユーサーで細かく砕き乾燥した大麦
の若葉粉末４Kg、大根の若葉粉末2.4Kg、菜種子
菜粉末２Kgおよび、ごまを約70℃でこげないよう
に加熱したのちすり潰して絞つたごま油1.4Kgと
少量のオリーブ油とを混合し、再度32℃で24時間
インクベートしたのち、−５℃で約30分間温風を
送り込みながら冷凍乾燥し、さらに32℃で約30分
間乾燥したのち、室温で３日間養生し漢方薬を得
た。
得られた漢方薬を１日３回、１回３ｇを患者に
服用させ、第４表の結果を得た。[Table] Example 5 500g of germ that was heated to about 70℃ without burning and then ground, 7.6Kg of brown rice and 100 koji mold
g were mixed and incubated at 32°C for 24 hours. Add to this 4 kg of young barley powder that has been finely crushed and dried using a juicer, 2.4 kg of young radish powder, 2 kg of rapeseed powder, and 1.4 kg of sesame oil that has been heated to about 70℃ without burning, then ground and squeezed. After mixing with a small amount of olive oil and incubating again at 32℃ for 24 hours, freeze-drying at -5℃ while blowing warm air for about 30 minutes, drying at 32℃ for about 30 minutes, and then at room temperature for 3 days. I took care of myself and obtained Chinese medicine. The obtained Chinese herbal medicine was administered to a patient at a dose of 3 g three times a day, and the results shown in Table 4 were obtained.
【表】
ｇ 発明の効果
本発明の漢方薬は、現代の難病で最適の治療方
法がないとまで言われる高度の冷え症、レイノー
氏病、悪性関節リユーマチ、ベーチエツト病ある
いはシミ・ソバカスに有効である。
本発明の漢方薬は合成化学薬品ではないので一
切副作用はない。
本発明１〜５のそれぞれの効果は次の如くであ
る。
即ち本発明１の漢方薬は、スーパーオキシドジ
ズムターゼ（SOD）を含むアンチオキシダント
作用を示す低分子化合物が含まれているため、血
流障害回復に有効であるので高度の冷え症、レイ
ノー氏病に効果がある。
本発明２は、本発明１に加えビタミンＣが多量
に含まれているため、アンチオキシダント作用が
強化され、活性酸素除去作用が本発明１より強力
になり、冷え症、レイノー氏病のほか関節リユー
マチやベーチエツト病にも有効である。
本発明３は、ビタミンB2、ＣおよびＡが多量
に含まれているので、過酸化脂質除去作用が強化
され、血流障害回復作用が強力になり、上記各疾
病ほか、シミ・ソバカスといつた従来まつたく治
す方法がなかつた症状にまで効果を発揮するもの
である。
本発明４は、リンパ球異常反応の抑制に効果が
あり、難病の冷え症、レイノー氏病、悪性関節リ
ユーマチに特に有効であり、ベーチエツト病およ
びシミ・ソバカスにも有効がある。
本発明５は、胃潰瘍や、胃弱の患者に長期間投
与する場合を考慮して緑茶を除いたたものであ
り、発明４とほぼ同の効果を示す。[Table] g Effects of the Invention The herbal medicine of the present invention is effective for severe sensitivity to cold, Raynaud's disease, malignant rheumatoid arthritis, Behchiet's disease, and age spots and freckles, which are considered to be incurable diseases for which there is no optimal treatment method. Since the herbal medicine of the present invention is not a synthetic chemical, there are no side effects. The respective effects of the present inventions 1 to 5 are as follows. In other words, the Chinese herbal medicine of the present invention 1 contains a low-molecular-weight compound that exhibits an antioxidant effect, including superoxide dismutase (SOD), and is effective in recovering from blood flow disorders, so it is effective for severe sensitivity to cold and Raynaud's disease. There is. Invention 2 contains a large amount of vitamin C in addition to Invention 1, so the antioxidant effect is strengthened and the active oxygen removal effect is stronger than Invention 1, and it is effective against cold sensitivity, Raynaud's disease, and rheumatoid arthritis. It is also effective against Bethiett's disease. Invention 3 contains large amounts of vitamins B 2 , C, and A, so the lipid peroxide removal effect is strengthened, and the blood flow disorder recovery effect is strong. It is also effective for symptoms for which there was no cure until now. The present invention 4 is effective in suppressing abnormal lymphocyte reactions, and is particularly effective against incurable diseases such as sensitivity to cold, Raynaud's disease, and malignant rheumatoid arthritis, and is also effective against Behchiet's disease and age spots and freckles. Invention 5 excludes green tea in consideration of long-term administration to patients with gastric ulcers or weak stomachs, and exhibits almost the same effect as Invention 4.
Claims (1)
高度の冷え症状等の治療用漢方薬。 ２ こうじかび、胚芽、大麦の若葉および緑茶か
らなる高度の冷え症状等の治療用漢方薬。 ３ こうじかび、胚芽、大麦の若葉、緑茶、玄米
およびごまからなる高度の冷え症状等の治療用漢
方薬。 ４ こうじかび、胚芽、大麦の若葉、緑茶、玄
米、ごま、大根の若葉および菜種子菜からなる高
度の冷え症状等の治療用漢方薬。 ５ こうじかび、胚芽、大麦の若葉、玄米、ご
ま、大根の若葉および菜種子菜からななる高度の
冷え症状等の治療用漢方薬。[Scope of Claims] 1. A Chinese herbal medicine for treating severe cold symptoms, etc., consisting of Koji mold, germ, and young barley leaves. 2. A Chinese herbal medicine for treating severe cold symptoms, etc., consisting of Koji mold, germ, young barley leaves, and green tea. 3. A Chinese herbal medicine for treating severe cold symptoms, etc., consisting of Koji mold, germ, young barley leaves, green tea, brown rice, and sesame. 4. A Chinese herbal medicine for treating severe cold symptoms, etc., consisting of Koji mold, germ, young barley leaves, green tea, brown rice, sesame, young radish leaves, and rapeseed rape. 5. A Chinese herbal medicine for treating symptoms such as severe cold symptoms, consisting of Koji mold, germ, young barley leaves, brown rice, sesame, young radish leaves, and rapeseed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60174735A JPS6236327A (en) | 1985-08-08 | 1985-08-08 | Chinese herbal remedy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60174735A JPS6236327A (en) | 1985-08-08 | 1985-08-08 | Chinese herbal remedy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6236327A JPS6236327A (en) | 1987-02-17 |
| JPH0456806B2 true JPH0456806B2 (en) | 1992-09-09 |
Family
ID=15983748
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60174735A Granted JPS6236327A (en) | 1985-08-08 | 1985-08-08 | Chinese herbal remedy |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6236327A (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2610325B2 (en) * | 1988-12-05 | 1997-05-14 | 拓壬 中村 | Active oxygen suppression composition |
| JP2603359B2 (en) * | 1990-07-13 | 1997-04-23 | 萩原 義秀 | Antithrombotic agent |
| JP2955126B2 (en) * | 1992-06-22 | 1999-10-04 | 笑代 丹羽 | Pharmaceutical oleaginous preparation, food oleaginous preparation and production method thereof |
| AU756766B2 (en) * | 1998-02-06 | 2003-01-23 | Yoshio Yamamoto | Mixed fine powder for beverage containing young barley leaves, alfalfa and/or kale |
| KR100318051B1 (en) * | 1999-03-25 | 2001-12-22 | 채재호 | The method for preparing an embryo bud for tea |
| JP7222559B2 (en) * | 2021-02-19 | 2023-02-15 | 株式会社東洋新薬 | Specific ingredient-containing composition |
-
1985
- 1985-08-08 JP JP60174735A patent/JPS6236327A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6236327A (en) | 1987-02-17 |
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