JPH048063B2 - - Google Patents
Info
- Publication number
- JPH048063B2 JPH048063B2 JP62102768A JP10276887A JPH048063B2 JP H048063 B2 JPH048063 B2 JP H048063B2 JP 62102768 A JP62102768 A JP 62102768A JP 10276887 A JP10276887 A JP 10276887A JP H048063 B2 JPH048063 B2 JP H048063B2
- Authority
- JP
- Japan
- Prior art keywords
- hollow
- housing
- cup
- fiber bundle
- fibers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Landscapes
- External Artificial Organs (AREA)
Description
【発明の詳細な説明】
（産業上の利用分野）
本発明はホローフアイバー（中空糸）型人工臓
器の製造方法に関し、特にホローフアイバーをハ
ウジング内に均一に分散させたホローフアイバー
型人工臓器の製造方法に関する。Detailed Description of the Invention (Field of Industrial Application) The present invention relates to a method for manufacturing a hollow fiber type artificial organ, and particularly to a method for manufacturing a hollow fiber type artificial organ in which hollow fibers are uniformly dispersed within a housing. Regarding the method.
（従来の技術）
従来、ホローフアイバー型人工臓器の製造方法
としてはハウジング内にホローフアイバー束を挿
入し一本一本手或は機械でほぐし、次に該ホロー
フアイバーの一方の末端部を仮止用樹脂液で仮止
固定したのちホローフアイバー束の他方の末端部
をハウジングの端部にポリウレタンなどのポツテ
イング剤によつて固着し、しかる後先のホローフ
アイバー末端部の仮止固定部分をカツター等で裁
断しハウジングの端部に固着している。然し乍
ら、このような従来の方法ではホローフアイバー
束の末端部を樹脂液で仮止固定する場合、樹脂液
が高粘性のためホローフアイバーは偏りやすく均
一に分散しないという欠点があつた。この欠点を
除く為にホローフアイバー束の端部の中心部にボ
ール等を入れ、これによつてホローフアイバーを
均一に分散させる方法が行なわれているが、この
方法でもハウジング端面の中心部においてホロー
フアイバーが疎になりやすいという欠点があつ
た。(Prior art) Conventionally, the method for manufacturing a hollow eye bar type artificial organ involves inserting a bundle of hollow eye bars into a housing, loosening each bundle by hand or machine, and then temporarily fixing one end of the hollow eye bar. After temporarily fixing the hollow fiber bundle with a resin solution, the other end of the hollow fiber bundle is fixed to the end of the housing with a potting agent such as polyurethane, and then the temporary fixing part of the hollow fiber bundle is fixed with a cutter or the like. It is cut and fixed to the end of the housing. However, in this conventional method, when the end portion of a bundle of hollow fibers is temporarily fixed with a resin liquid, the resin liquid has a high viscosity, so the hollow fibers tend to be uneven and cannot be dispersed uniformly. In order to eliminate this drawback, a method is used in which a ball or the like is inserted into the center of the end of the bundle of hollow fibers to evenly disperse the hollow fibers. The disadvantage was that the fibers tend to become sparse.
（発明が解決しようとする問題点）
本発明は前述の従来方法における欠点を解決す
るためになされたものであつて、その目的は簡単
な手段によりハウジング内のホローフアイバーを
均一に分散させたホローフアイバー型人工臓器の
製造方法を提供するにある。(Problems to be Solved by the Invention) The present invention has been made in order to solve the drawbacks of the conventional method described above, and its purpose is to provide a hollow fiber in which the hollow fibers in the housing are uniformly dispersed by a simple means. The present invention provides a method for manufacturing a fiber-type artificial organ.
（問題点を解決するための手段）
すなわち、本発明は、複数のホローフアイバー
よりなるホローフアイバー束をハウジング内に挿
入し、その両端をポツテイング材でハウジング内
に固着してホローフアイバー型人工臓器を製造す
るに当り、前記ホローフアイバー束をハウジング
内に挿入した後、ハウジングの端部に底面部と側
壁部とから構成されて脱着が容易な２つの部分か
らなるカツプ状部材の側壁部を装着し、前記ホロ
ーフアイバー束を分散した後、前記底面部を装着
して、該カツプ部材の底面部に少量の仮止剤を存
在させてハウジング内のホローフアイバー束の末
端部を該底面部に仮固定、目止めを行つた後、必
要量のポツテイング材をハウジング内に注入して
ホローフアイバーを固着することを特徴とするホ
ローフアイバー型人工臓器の製造方法である。(Means for Solving the Problems) That is, the present invention provides a hollow eye bar type artificial organ by inserting a hollow eye bar bundle consisting of a plurality of hollow eye bars into a housing, and fixing both ends of the bundle within the housing with potting material. In manufacturing, after inserting the hollow fiber bundle into the housing, a side wall portion of a cup-shaped member consisting of two parts that can be easily attached and detached is attached to the end of the housing. After dispersing the hollow fiber bundle, attach the bottom part and temporarily fix the end part of the hollow fiber bundle in the housing to the bottom part by applying a small amount of temporary adhesive to the bottom part of the cup member. , a method for producing a hollow eye-shaped artificial organ, characterized in that after sealing, a necessary amount of potting material is injected into the housing to fix the hollow eye.
すなわち、本発明ではホローフアイバー束の端
部を仮止剤で仮止固定するに際し、着脱容易な底
面部と側壁部とから構成されている２つの部品か
らなるカツプ状部材を使用するものであつて、複
数のフアイバーをハウジング内に均一に分散する
際には側壁部のカツプのみを装着し端面が開放さ
れた状態で使用する。尚、カツプ状部材としては
シヤーレ等の底の浅いものも含まれる。また、ホ
ローフアイバー端面を仮固定、目止めを行うに際
しては底面部カツプを装着後に仮止剤を注入して
もよく、または予め底面カツプに少量の仮止剤を
入れた状態で装着してもよい。ここで、「目止め」
とは遠心機にかけたときにポツテイング剤がホロ
ーフアイバー内部に入りこまないように端部を閉
鎖させることをいう。そして、ホローフアイバー
の末端部を仮固定、目止めを行つた後必要量のポ
ツテイング材を例えばハウジングのポート部より
遠心等により注入し、しかるのち２つの部分より
なるカツプ状部材をはずしてホローフアイバーの
末端部をカツトして人工臓器を組み立てるのであ
る。 That is, in the present invention, when temporarily fixing the ends of a hollow fiber bundle with a temporary fixing agent, a cup-shaped member is used, which is made up of two parts consisting of a bottom part and a side wall part, which can be easily attached and detached. Therefore, when distributing a plurality of fibers uniformly within the housing, only the side wall cup is attached and the end face is left open. Incidentally, the cup-shaped member includes a shallow-bottomed member such as a shear cup. In addition, when temporarily fixing or sealing the hollow eye bar end face, you may inject a temporary adhesive after installing the bottom cup, or you may place a small amount of temporary adhesive in the bottom cup beforehand. good. Here, "stop your eyes"
This means that the ends are closed to prevent the potting agent from entering the inside of the hollow eye when it is centrifuged. After temporarily fixing and sealing the end of the hollow eye bar, the required amount of potting material is injected, for example, by centrifugation from the port of the housing, and then the cup-shaped member consisting of two parts is removed and the hollow eye bar is closed. The artificial organ is assembled by cutting off the end of the organ.
また、本発明の分散は、ハウジングの端部に底
面部と側壁部とから構成されて脱着が容易な２つ
の部分からなるカツプ状部材の側壁部を装着した
後、前記ホローフアイバー束を分散するのである
が、その分散は、フアイバー端面をエアーを吹き
付けることによつて達成される。エアーを吹き付
ける手段としては、口径約１〜10mm程度のノズル
先端より吹き付けるのがよく、その送風量として
は60〜400／minであり、その風圧としては0.5
Kg／cm2、ノズルとフアイバー束端の距離は５〜80
mmで、ノズルは１つでも複数でもよい。 Further, in the dispersion of the present invention, the hollow fiber bundle is dispersed after the side wall part of the cup-shaped member, which is composed of two parts that are easy to attach and detach, is attached to the end part of the housing, and is composed of a bottom part and a side wall part. However, the dispersion is achieved by blowing air onto the end face of the fiber. As a means of blowing air, it is best to blow from the tip of a nozzle with a diameter of about 1 to 10 mm, the air flow rate is 60 to 400/min, and the wind pressure is 0.5
Kg/cm 2 , distance between nozzle and fiber bundle end is 5~80
mm, and the number of nozzles may be one or more.
次に本発明を図面について更に具体的に説明す
る。図面において１はハウジング、２はホローフ
アイバー束、３はポートである。今、ハウジング
内にホローフアイバー束を挿入し、続いて側壁部
及び底面部よりなるカツプ状部材４，５をハウジ
ング端面に装着する（第１図参照）。この場合、
底面部を構成するカツプ状部材５には予め仮止剤
７を入れておき、ホローフアイバーの端部を仮止
固定すると共に目止を行う。しかる後、他方の端
部に上方よりノズルから空気を吹き付けホローフ
アイバー束の各ホローフアイバー端部を均一に分
散させる（第２図参照）。それからポートよりポ
リウレタンなどのポツテイング材を注入しハウジ
ング内壁と分散させたホローフアイバーとの間及
び各ホローフアイバー間を固着する（第３図参
照）。次に、ホローフアイバー束の仮止部分のカ
ツプ状部材をはずし、仮止め部分を裁断したのち
先の場合と同様に該末端部にノズルから空気を吹
き付けて均一に分散させた後ポツテイング材で固
着する。 Next, the present invention will be explained in more detail with reference to the drawings. In the drawings, 1 is a housing, 2 is a hollow fiber bundle, and 3 is a port. Now, insert the hollow fiber bundle into the housing, and then attach the cup-shaped members 4 and 5, which are made up of side walls and a bottom surface, to the end surface of the housing (see FIG. 1). in this case,
A temporary fixing agent 7 is placed in advance in the cup-shaped member 5 constituting the bottom part, and the ends of the hollow fibers are temporarily fixed and sealed. Thereafter, air is blown onto the other end from a nozzle from above to uniformly disperse the ends of each hollow fiber in the bundle of hollow fibers (see FIG. 2). Then, a potting material such as polyurethane is injected through the port to fix the space between the inner wall of the housing and the dispersed hollow fibers and between each hollow fiber (see FIG. 3). Next, remove the cup-shaped member from the temporarily fastened part of the hollow fiber bundle, cut the temporarily fastened part, and then, as in the previous case, blow air from the nozzle to the end to distribute it evenly, and then fix it with potting material. do.
本発明の方法によつてフアイバーの内外径
200μ×240μ本数62000本からなるフアイバー束を
用いハウジング内に挿入後その端部に風量200
／分のエアーを８分間吹き付けたところフアイ
バーが均一に分散した人工肺が得られた。 By the method of the present invention, the inner and outer diameters of the fibers can be reduced.
A fiber bundle consisting of 62,000 200μ x 240μ fibers is inserted into the housing and the end of the fiber bundle has an air volume of 200.
When air was blown for 8 minutes at a rate of 1/2 min, an oxygenator in which the fibers were uniformly dispersed was obtained.
（発明の効果）
以上述べたように、複数のホローフアイバーを
ハウジング内に仮止固定する際に着脱の容易な２
の部分よりなるカツプ状部材を使用し、フアイバ
ーを均一に分散させるときは側壁部のカツプをセ
ツトした状態で行うのでフアイバーの末端部は開
放されていたため十分な分散が可能であり、また
仮止固定するときは底面部のカツプに仮止剤を入
れて行うので、良好な分散状態を保持したまま仮
止固定が行えるので疎密化が防げ、更にこの状態
で遠心によりポツテイング材を注入した場合にも
フアイバーの疎密がなく、フアイバーは均一に分
散された状態でポツテイングを行うことができ、
リークの発生もない。(Effects of the Invention) As described above, when a plurality of hollow eye bars are temporarily fixed in a housing, it is possible to easily attach and detach two
When dispersing the fibers uniformly, the cup on the side wall is set, so the ends of the fibers are open, allowing for sufficient dispersion. When fixing, a temporary fixing agent is put into the bottom cup, so temporary fixing can be done while maintaining a good dispersion state, which prevents densification.Furthermore, when potting material is injected by centrifugation in this state, Also, there is no density of fibers, and potting can be performed with the fibers evenly distributed.
No leaks occur.
第１図ないし第３図は本発明の製造方法を工程
を示す説明図である。
１……ハウジング、２……ホローフアイバー、
３……ポート、４……カツプ状部材の側壁部、５
……カツプ状部材の底面部、６……エアーノズ
ル、７……仮止剤。
1 to 3 are explanatory diagrams showing steps of the manufacturing method of the present invention. 1...Housing, 2...Hollow eye bar,
3... Port, 4... Side wall portion of cup-shaped member, 5
...Bottom part of the cup-shaped member, 6...Air nozzle, 7...Temporary adhesive.
Claims (1)
イバー束をハウジング内に挿入し、その両端をポ
ツテイング材でハウジング内に固着してホローフ
アイバー型人工臓器を製造するに当り、前記ホロ
ーフアイバー束をハウジング内に挿入した後、ハ
ウジングの端部に底面部と側壁部とから構成され
て脱着が容易な２つの部分からなるカツプ状部材
の側壁部を装着し、前記ホローフアイバー束を分
散した後、前記底面部を装着して、該カツプ部材
の底面部に少量の仮止剤を存在させてハウジング
内のホローフアイバー束の末端部を該底面部に仮
固定、目止めを行つた後、必要量のポツテイング
材をハウジング内に注入してホローフアイバーを
固着することを特徴とするホローフアイバー型人
工臓器の製造方法。1. A hollow eye bar bundle consisting of a plurality of hollow eye bars was inserted into a housing, and both ends thereof were fixed in the housing with a potting material to manufacture a hollow eye bar type artificial organ. After that, a side wall part of a cup-shaped member consisting of two parts that is easy to attach and detach, which is composed of a bottom part and a side wall part, is attached to the end of the housing, and after dispersing the hollow fiber bundle, the bottom part is attached. Then, by applying a small amount of temporary adhesive to the bottom of the cup member, the end of the hollow fiber bundle in the housing is temporarily fixed and sealed to the bottom, and then a necessary amount of potting material is attached to the housing. A method for manufacturing a hollow eye bar type artificial organ, characterized by fixing a hollow eye bar by injecting the hollow eye bar into the organ.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10276887A JPS63267365A (en) | 1987-04-24 | 1987-04-24 | Preparation of hollow fiber type artificial internal organs |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10276887A JPS63267365A (en) | 1987-04-24 | 1987-04-24 | Preparation of hollow fiber type artificial internal organs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS63267365A JPS63267365A (en) | 1988-11-04 |
| JPH048063B2 true JPH048063B2 (en) | 1992-02-13 |
Family
ID=14336351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10276887A Granted JPS63267365A (en) | 1987-04-24 | 1987-04-24 | Preparation of hollow fiber type artificial internal organs |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS63267365A (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2544014A1 (en) * | 1975-10-02 | 1977-04-14 | Hoechst Ag | POLAR PHENOLIC ANTIOXIDANTS FOR THE STABILIZATION OF PLASTICS |
| JPS6282970A (en) * | 1985-10-04 | 1987-04-16 | テルモ株式会社 | Production of hollow fiber type substance replacing apparatus |
-
1987
- 1987-04-24 JP JP10276887A patent/JPS63267365A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS63267365A (en) | 1988-11-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0102539B1 (en) | A hollow thread device for removing waste material in the blood and a process of manufacture thereof | |
| KR880701123A (en) | Golf club bag and its manufacturing method | |
| JPS6470107A (en) | Diffusion-filtration apparatus and method for making the same | |
| DE69328731T2 (en) | Method of manufacturing a fiber optic coupler | |
| US6432345B1 (en) | Single-step method of manufacturing a silicone tube manifold | |
| JPH048063B2 (en) | ||
| JP2004050011A (en) | Method for manufacturing hollow fiber membrane module and hollow fiber membrane module | |
| KR20000053798A (en) | Method of coating a pole and the pole maked the same method | |
| JP2751463B2 (en) | Method for manufacturing hollow fiber membrane module | |
| JPH0237791B2 (en) | ||
| JPS54152681A (en) | Hollow fiber type mass transfer apparatus and manufacture thereof | |
| JPH061287B2 (en) | Adhesive fixing method for optical fiber connector and adhesive container | |
| ATE151562T1 (en) | METHOD FOR PRODUCING AN INSULATOR | |
| KR20010024847A (en) | Hemodialyzer fiber bundle encapsulation process | |
| KR100358679B1 (en) | Method of coating a pole and the pole maked the same method | |
| JPH01284305A (en) | Manufacturing method of hollow fiber membrane filtration module | |
| JPH0560951B2 (en) | ||
| JPH0582247B2 (en) | ||
| CN217103051U (en) | Medicament filling auxiliary device | |
| JPS6218499B2 (en) | ||
| JPH02214527A (en) | Fiber fixing tool and production of fluid treating vessel with same | |
| JPS56141801A (en) | Production of connected part of hollow fiber bundle end | |
| JP2596001Y2 (en) | External pressure filtration type hollow fiber membrane module | |
| JP3046086B2 (en) | Resin fixing method for hollow fiber membrane bundle | |
| JPS5828222A (en) | Chemical liquid foaming and coating net |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| LAPS | Cancellation because of no payment of annual fees |