JPH0553135B2 - - Google Patents

Description

[Detailed description of the invention]

[Object of the invention] (Industrial application field) The present invention relates to a condom with a jelly agent, and more specifically, a condom with a jelly agent that maintains a stable jelly state over a long period of time,
The present invention also relates to a condom with a jelly agent that is highly colorfast. (Prior Art) Conventionally, condoms with a jelly agent have been known, in which a jelly agent is applied to the condom in order to impart lubricity to the condom. When the jelly is applied, various ingredients are mixed into the jelly depending on various purposes. For example, additives, antibacterial agents, spermicides, etc. are appropriately mixed in to ensure the long-term stability of the condom, especially to prevent swelling and whitening of the rubber. Typical components of the above-mentioned jelly agent include glycerin, gelatin, white sugar, purified water, paraoxybenzoic acid ester, and the like. To prepare a jelly from these components, for example, gelatin is added to purified water and dissolved while heating. Next, glycerin and paraoxybenzoic acid ester (eg, butyl paraoxybenzoate) are added to the white sugar, and the mixture is heated and dissolved at 80 to 85°C. After heating and dissolving, the mixture is left at room temperature and water lost through evaporation is replenished to prepare a jelly. Among the constituent components of the jelly mentioned above, glycerin is mainly used to provide lubricity and moisturizing properties.
Gelatin is used to impart viscosity. In addition, sucrose is used to prevent purified water used for preparing jelly preparations from transferring to the rubber through osmotic pressure, thereby preventing swelling and whitening of the rubber. It goes without saying that the glycerin component also has the function of preventing the migration of purified water into the rubber through osmotic pressure. Furthermore, paraoxybenzoic acid ester is added as a preservative or an antibacterial agent, and is effective for long-term storage, prevention of vaginitis, and prevention of sexually transmitted diseases. In addition, spermicides have recently been added to condoms to make them more effective at preventing pregnancy. As this type of spermicide, polyoxyethylene nonionic surfactants such as polyoxyethylene nonyl phenyl ether with a chain length of about 8 to 10 are used (Japanese Patent Publication No. 63
-28620, US Pat. No. 4,795,425). In the above-mentioned condom with jelly, there is a problem that the jelly changes color due to heating conditions during manufacturing, long-term storage after manufacturing, etc. For example, when we examine a sample that has been stored for 5 years, even when stored at room temperature, there is a clear difference in color compared to the sample immediately after manufacture, which greatly reduces the commercial value. (Problems to be Solved by the Invention) The present invention provides a condom with a jelly agent that includes:
In particular, the object of the present invention is to prevent discoloration of conventional jelly preparations that use white sugar as one of the jelly ingredients over a long period of time, and to provide a condom with jelly preparations that has high commercial value. [Structure of the Invention] To summarize the present invention, the first invention is a condom with a jelly agent, characterized in that the jelly agent consists of glycerin, gelatin, sorbitol and/or maltitol, purified water, and paraoxybenzoic acid ester. The second invention relates to a condom with a color-fast jelly agent, in which polyoxyethylene nonyl phenyl ether is further added to the constituent components of the jelly agent of the first invention in order to particularly enhance the spermicidal effect. The present invention relates to a condom with a spermicidal and discoloration-resistant jelly agent. Hereinafter, the configuration of the present invention will be explained in detail. As mentioned above, the jelly used in conventional jelly-containing condoms, specifically the jelly made of glycerin, gelatin, white sugar, purified water, etc., has the disadvantage of discoloration during storage. It is something that you have. The present inventors conducted research on the above-mentioned discoloration problem based on the assumption that this is an expression of a cutlet discoloration phenomenon based on the Maillard reaction between amino acids, which are components of gelatin, and sugars. . As is well known, the Maillard reaction is a deformation phenomenon that occurs when an aqueous mixed solution of amino acids and reducing sugars is heated. On the other hand, white sugar (also called sucrose, which is a non-reducing disaccharide) is not a reducing sugar, so the Maillard reaction is weak, but its constituent monosaccharides (all monosaccharides are reducing sugars) contain impurities. ), the katsu-hen phenomenon occurs. Therefore, white sugar can be replaced with other sugars, but white sugar has the important function of preventing the purified water in the jelly from migrating into the rubber, as mentioned above. As a result of examining substances that can replace white sugar, we found that the water retention properties of sugars are monosaccharides < disaccharides (such as white sugar) < polysaccharides < sugar alcohols (such as sorbitol and maltitol), and these It has been found that when sorbitol or maltitol is used as a component of a jelly, it has a better effect than white sugar.
Moreover, these sorbitol and maltitol are superior in cost merit to white sugar and are safe for living systems. The present invention has been made against the above-mentioned background, and a major feature of the present invention is that, in a condom with a jelly, sorbitol or maltitol is used as a component of the jelly instead of conventional white sugar. It is something. Therefore, the important components constituting the jelly of the present invention are glycerin, gelatin, sorbitol and/or maltitol, purified water, and paraoxybenzoic acid ester.
In order to ensure that the condom has sufficient spermicidal properties, the important ingredients constituting the jelly of the present invention are glycerin, gelatin, sorbitol and/or maltitol, purified water, paraoxybenzoic acid ester, polyoxyethylene nonyl It consists of phenyl ether. In the present invention, in addition to the above-described constituent components of the jelly, vitamin E (dl-α tocopherol)
It goes without saying that conventional compounding ingredients such as antioxidants such as the following can be used. (Examples) Hereinafter, the present invention will be explained in detail with reference to Examples, but the present invention is not limited to the Examples. Examples 1 to 4/Comparative Examples 1 to 2 Jelly preparations were prepared according to the formulations shown in Table 1 below (the usage ratio of each component is % by weight). The procedure for preparing the jelly agent is as follows. 1 Add gelatin to purified water and dissolve while heating. 2 ● Next, add sucrose and glycerin (comparative example) ● Next, add sorbitol and/or maltitol and glycerin (example) 3 Add butyl paraoxybenzoate (abbreviated as paraben in Table 1) Add. 4 Heat to a maximum of 85℃ to dissolve. 5 Leave at room temperature and replenish moisture lost through evaporation.

[Table] <Colorimetric test of jelly> A colorimetric test was conducted according to the following procedure. The results are shown in Tables 2 and 3. 1. Take 50 ml of heated and dissolved jelly into a 300 ml airtight container. 2 Placed in a thermostat at 40°C, removed after 10 days, and measured color difference using a self-recording spectrophotometer: UV-265 (Color Pack System) manufactured by Shimadzu Corporation (No. 2).
table). 3 The color difference of the jelly maintained at 70°C for 5 days was measured using Σ-80 manufactured by Nippon Denshoku Industries Co., Ltd. (Table 3). The measured values of the colorimetric test in Tables 2 and 3 below have the following meanings: L...The larger the value, the higher the lightness (brighter). A...The larger the value is on the (+) side, the more red it is, (-)
On the side, the larger the number, the greater the degree of green. B...On the (+) side, the larger the number, the more yellow, (-)
On the side, the larger the number, the greater the degree of blue.

【table】

〔Effect of the invention〕

Since the condom with jelly of the present invention does not contain white sugar components that cause discoloration by reacting with gelatin, which is an essential component of jelly, discoloration is prevented over a long period of time, and the condom is stable over a long period of time. A jelly state is obtained. Furthermore, since sorbitol and/or maltitol components are used instead of white sugar components, there is a cost advantage, and a condom with a jelly agent that is inexpensive and has high commercial value can be provided.

Claims (1)

[Scope of Claims] 1. A condom with a jelly agent, characterized in that the jelly agent comprises glycerin, gelatin, sorbitol and/or maltitol, purified water, and paraoxybenzoic acid ester. condom. 2. A condom with a jelly agent, which is spermicidal and characterized in that the jelly agent consists of glycerin, gelatin, sorbitol and/or maltitol, purified water, paraoxybenzoic acid ester, and polyoxyethylene nonyl phenyl ether. Condom with colorfast jelly.