JPH0662379B2 - Dental material composition - Google Patents
Dental material compositionInfo
- Publication number
- JPH0662379B2 JPH0662379B2 JP63060548A JP6054888A JPH0662379B2 JP H0662379 B2 JPH0662379 B2 JP H0662379B2 JP 63060548 A JP63060548 A JP 63060548A JP 6054888 A JP6054888 A JP 6054888A JP H0662379 B2 JPH0662379 B2 JP H0662379B2
- Authority
- JP
- Japan
- Prior art keywords
- metal
- material composition
- dental material
- antibacterial
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title claims description 17
- 239000005548 dental material Substances 0.000 title claims description 15
- 239000002184 metal Substances 0.000 claims description 30
- 229910052751 metal Inorganic materials 0.000 claims description 30
- 239000003242 anti bacterial agent Substances 0.000 claims description 10
- 150000002484 inorganic compounds Chemical class 0.000 claims description 9
- 229910010272 inorganic material Inorganic materials 0.000 claims description 9
- 229910052709 silver Inorganic materials 0.000 claims description 7
- 229910052725 zinc Inorganic materials 0.000 claims description 7
- 239000011701 zinc Substances 0.000 claims description 7
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 6
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 6
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 6
- 229910052802 copper Inorganic materials 0.000 claims description 6
- 239000010949 copper Substances 0.000 claims description 6
- 239000000945 filler Substances 0.000 claims description 6
- 239000004332 silver Substances 0.000 claims description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 5
- 210000004262 dental pulp cavity Anatomy 0.000 claims description 5
- 229910021645 metal ion Inorganic materials 0.000 claims description 5
- 239000011347 resin Substances 0.000 claims description 5
- 229920005989 resin Polymers 0.000 claims description 5
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 4
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 4
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 4
- WUKWITHWXAAZEY-UHFFFAOYSA-L calcium difluoride Chemical group [F-].[F-].[Ca+2] WUKWITHWXAAZEY-UHFFFAOYSA-L 0.000 claims description 3
- 239000003479 dental cement Substances 0.000 claims description 3
- 239000002808 molecular sieve Substances 0.000 claims description 3
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 claims description 3
- 239000010457 zeolite Substances 0.000 claims description 3
- 239000005909 Kieselgur Substances 0.000 claims description 2
- 229910021536 Zeolite Inorganic materials 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims description 2
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims description 2
- 239000004927 clay Substances 0.000 claims description 2
- 239000000805 composite resin Substances 0.000 claims description 2
- GUJOJGAPFQRJSV-UHFFFAOYSA-N dialuminum;dioxosilane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[O-2].[Al+3].[Al+3].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O GUJOJGAPFQRJSV-UHFFFAOYSA-N 0.000 claims description 2
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims description 2
- -1 gyorekite Chemical compound 0.000 claims description 2
- 229910052901 montmorillonite Inorganic materials 0.000 claims description 2
- 239000000377 silicon dioxide Substances 0.000 claims 1
- 230000000844 anti-bacterial effect Effects 0.000 description 18
- 150000003839 salts Chemical class 0.000 description 17
- 239000000126 substance Substances 0.000 description 14
- 150000002739 metals Chemical class 0.000 description 9
- 241000894006 Bacteria Species 0.000 description 6
- 208000002925 dental caries Diseases 0.000 description 6
- 206010006326 Breath odour Diseases 0.000 description 5
- 241000222120 Candida <Saccharomycetales> Species 0.000 description 5
- 208000003265 stomatitis Diseases 0.000 description 5
- 239000007864 aqueous solution Substances 0.000 description 4
- 229920000642 polymer Polymers 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000000839 emulsion Substances 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000000465 moulding Methods 0.000 description 3
- 210000000214 mouth Anatomy 0.000 description 3
- 150000001450 anions Chemical class 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 description 2
- 238000005342 ion exchange Methods 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000000704 physical effect Effects 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 description 2
- WHRZCXAVMTUTDD-UHFFFAOYSA-N 1h-furo[2,3-d]pyrimidin-2-one Chemical compound N1C(=O)N=C2OC=CC2=C1 WHRZCXAVMTUTDD-UHFFFAOYSA-N 0.000 description 1
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 description 1
- 239000005770 Eugenol Substances 0.000 description 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 1
- 208000032139 Halitosis Diseases 0.000 description 1
- 235000006173 Larrea tridentata Nutrition 0.000 description 1
- 244000073231 Larrea tridentata Species 0.000 description 1
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 description 1
- 241000295644 Staphylococcaceae Species 0.000 description 1
- 239000005844 Thymol Substances 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000004568 cement Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229960002126 creosote Drugs 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229960002217 eugenol Drugs 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 229910001410 inorganic ion Inorganic materials 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 239000011368 organic material Substances 0.000 description 1
- 229920002866 paraformaldehyde Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 229960000790 thymol Drugs 0.000 description 1
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Dental Preparations (AREA)
Description
【発明の詳細な説明】 （産業上の利用分野） 本発明は、歯科材料組成物、詳しくは銀、銅及び亜鉛な
どの金属イオンを含有した金属含有無機化合物抗菌剤を
含有させた歯科材料組成物に関するものである。TECHNICAL FIELD The present invention relates to a dental material composition, specifically a dental material composition containing a metal-containing inorganic compound antibacterial agent containing a metal ion such as silver, copper and zinc. It is about things.
（従来の技術） 歯科材料、例えば床用レジン、人工歯、成形修復材、レ
ジン修復材、インレー修復材その他は口腔内で長期間使
用されるものであり、これらに雑菌、特にカンジダ菌が
繁殖し、口臭や口内炎を発生することが知られている。
雑菌の繁殖を妨げるため、抗菌剤の使用が考えられてい
るが、抗菌剤の殆んどが有機物であるため耐熱性に乏し
く、加えてカンジダ菌に有効なものが少いので、樹脂な
どに練り込んで成形加工し、長期間安全に口腔肉で使用
できるものが少ない。このため成形修復材としてのセメ
ントに、ユージノール、クレオソート、パラホルム及び
チモールなどが防腐剤として使用されている程度であ
る。従って長期間抗菌力、特にカンジダ菌に対する抗菌
力を保持した安全な抗菌物質を含有させた歯科材料組成
物の開発は、口臭、口内炎発生抑制のためにも口腔衛生
上重要な課題である。銀、銅及び亜鉛などの金属及びそ
れらの塩が強い抗菌力を有することは周知の事実であ
り、金属を金網又は特殊な成形物に加工して直接使用し
たり、それらの塩の水溶液をそのまま使用したり、或い
は金属又はその塩を繊維、合成樹脂、膜成形高分子溶液
又はエマルジョンなどに織り込んだり、吸着させたり、
コーティングさせたり、分散混入させたりして目的物に
含有させ雑菌の繁殖を防止する方法が数多く提案されて
いる。然しながら金属又はその塩は、その物理的性質に
より使用に制限をうけている。例えば、これらの金属又
は塩は、比重が大であるためエマルジョン又は膜成形高
分子溶液に分散させてもそれらの中で沈降し、均一に混
合することがむつかしく、又場合によっては高分子溶液
又は有機材料の性質に影響を及ぼす。金属塩を水溶液と
して利用することは便利であるが、有機性物質との均質
な混合がむつかしい。このため金属及びその塩は強い抗
菌力を有しながらあまり使用されていない。(Prior art) Dental materials such as floor resins, artificial teeth, molding restorative materials, resin restorative agents, inlay restorative agents, etc. are used for a long period of time in the oral cavity, and various bacteria, especially Candida, propagate on them. However, it is known to cause bad breath and stomatitis.
The use of antibacterial agents has been considered to prevent the growth of bacteria, but most of the antibacterial agents are organic substances, so they have poor heat resistance. There are few things that can be safely kneaded and molded and used as oral meat for a long time. For this reason, eugenol, creosote, paraform, thymol, etc. are used as preservatives in cement as a molding restorative material. Therefore, the development of a dental material composition containing a safe antibacterial substance having a long-term antibacterial activity, particularly an antibacterial activity against Candida, is an important issue in oral hygiene for suppressing the occurrence of bad breath and stomatitis. It is a well known fact that metals such as silver, copper and zinc and salts thereof have strong antibacterial activity, and the metal is processed into a wire mesh or a special molded product and directly used, or an aqueous solution of those salts is used as it is. Use, or weave or adsorb metal or its salt into fiber, synthetic resin, membrane forming polymer solution or emulsion,
Many methods have been proposed to prevent the propagation of various bacteria by coating or dispersing and mixing them into an intended product. However, the use of metals or their salts is limited by their physical properties. For example, since these metals or salts have a large specific gravity, even if they are dispersed in an emulsion or a film-forming polymer solution, it is difficult to settle in them and mix uniformly, and in some cases, the polymer solution or Affects the properties of organic materials. Although it is convenient to use the metal salt as an aqueous solution, homogeneous mixing with an organic substance is difficult. For this reason, metals and salts thereof have not been used so much while having strong antibacterial activity.
（発明が解決しようとする課題） 本発明は、口臭、口内炎抑制のため、長期間菌、特にガ
ンジダ菌に対し抗菌力を有する銀、銅及び亜鉛などの金
属のイオンを含有する金属含有無機化合物抗菌剤を含有
させた安全な歯科材料組成物即ち、床用レジン、コンポ
ジット、歯科用セメント、根管充填剤、ガッタパーチャ
ーポイント、覆髄根関充填剤、人工歯、その他を提供す
ることを目的としている。又これら金属含有無機化合物
抗菌剤が虫歯の原因となる口中の細菌（嫌気性菌、レン
サ球菌、ブドウ球菌）に対しても強い抗菌力を有するの
でこれらを含有させた歯科材料は虫歯の再発を防ぐこと
ができ、虫歯予防にも有効である。従って更に本発明は
虫歯の発生を抑制する歯科材料組成物を提供することを
別の目的としている。(Problems to be Solved by the Invention) The present invention provides a metal-containing inorganic compound containing ions of metals such as silver, copper and zinc, which have an antibacterial activity against long-term bacteria, particularly Gandida bacteria, for the control of halitosis and stomatitis. An object of the present invention is to provide a safe dental material composition containing an antibacterial agent, that is, a floor resin, a composite, a dental cement, a root canal filler, a gutta-perture point, a pulp capping root-filling agent, an artificial tooth, and the like. I am trying. In addition, these metal-containing inorganic compound antibacterial agents have strong antibacterial activity against bacteria in the mouth (anaerobic bacteria, streptococci, staphylococci) that cause dental caries, so dental materials containing them will not cause tooth decay. It can be prevented and is also effective in preventing tooth decay. Therefore, another object of the present invention is to provide a dental material composition for suppressing the occurrence of caries.
（課題を解決するための手段及び作用） 銀、銅及び亜鉛などの金属及びそれらの塩が抗菌性のあ
ることは公知の事実である。本発明は、これら物質が、
口臭、口内炎発生の一原因であるカンジダ菌に対し強い
抗菌作用を示すことにもとずき、これら金属のイオンを
無機物質に含有させて使用することにより、前記のよう
な金属及びその塩の性質により使途に対する制限が解消
でき、歯科材料組成物に任意の割合に分散させて安全に
使用できることを認めたことにより、なされたものであ
る。銀、銅及び亜鉛などの金属塩の水溶液を多孔性の無
機物質、例えばゼオライト、フッ石群、カイリョク石、
モレキュラーシーブ、パームチット、ハイドロキシアパ
タイト、モンモリロナイト、活性炭、酸性白土、活性ア
ルミナ、シリカゲル、ケイ藻土、その他で処理し、それ
ら無機物質に金属イオンを吸着、又は担持させることに
より、これら金属の抗菌性を阻害することなく、いかな
る無機、有機系物質とも均一に分散する物質を容易にえ
られることを知った。特に無機物質としてゼオライト、
フッ石群、モレキュラーシーブ、パームチット、ハイド
ロキシアパタイト、及びカイリョク石を使用するとそれ
らの無機物質がイオン交換能を有するため、これら金属
とのイオンの交換を生じ、金属イオンを強固に保持する
とともに金属塩の陰イオンを吸着しにくい。このため陰
イオンの影響をうけにくい。従って無機物質としてこれ
ら無機イオン交換体を使用することは安全性をより高い
抗菌効果をより長期間保持させるので好ましい。これら
無機物質に金属塩を吸着又はイオン交換することは常法
により容易に実施することができ、担持される金属イオ
ンの量は使用する無機物質及び金属塩の種類、使用する
金属塩水溶液濃度、処理温度、時間により任意に選択す
ることができ、担持された金属イオンは常法の分析によ
り容易に決定できる。(Means and Actions for Solving the Problems) It is a known fact that metals such as silver, copper and zinc and salts thereof have antibacterial properties. In the present invention, these substances are
Based on having a strong antibacterial action against Candida which is one of the causes of bad breath and stomatitis, by using the ions of these metals in an inorganic substance, the metal and its salts It was made by recognizing that the limitation on the purpose of use can be eliminated depending on the property and that the dental material composition can be dispersed in an arbitrary ratio and safely used. An aqueous solution of a metal salt such as silver, copper and zinc is used as a porous inorganic substance, for example, zeolite, fluorite group, gyorekite,
By treating with molecular sieves, palm chits, hydroxyapatite, montmorillonite, activated carbon, acid clay, activated alumina, silica gel, diatomaceous earth, etc., and adsorbing or carrying metal ions on these inorganic substances, the antibacterial properties of these metals are improved. We have found that it is possible to easily obtain a substance that is uniformly dispersed in any inorganic or organic substance without any inhibition. Zeolites, especially as inorganic substances,
When fluorite group, molecular sieve, palm chit, hydroxyapatite, and kairyokeki are used, their inorganic substances have an ion-exchange ability, so that the exchange of ions with these metals occurs and the metal salt is firmly retained and the metal salt is retained. It is difficult to adsorb the anions of. Therefore, it is less susceptible to the influence of anions. Therefore, it is preferable to use these inorganic ion exchangers as the inorganic substance because the safety is higher and the antibacterial effect is maintained for a longer period of time. Adsorption or ion exchange of metal salts to these inorganic substances can be easily carried out by a conventional method, and the amount of supported metal ions depends on the types of inorganic substances and metal salts used, the concentration of metal salt aqueous solution used, It can be arbitrarily selected depending on the treatment temperature and time, and the supported metal ion can be easily determined by a conventional analysis.
このようにして得られた金属塩を担持した金属含有無機
化合物抗菌剤を乾燥、微粉砕して無機、有機性の歯科材
料組成物と混合すると、金属又は金属塩そのもののよう
にエマルジョン又は有機溶液中に分散させても分離する
ことなく、均一に分散された材料をえることができ、加
熱成形によってもその抗菌力に変化を生じない。歯科材
料組成物への金属無機化合物抗菌剤の分散は出来るだけ
微粒子であることが望まれ５〜８０μ、好ましくは３０
μ前後に微粉砕して添加する。その添加量は特に限定さ
れないが有機歯科材料へ過剰の添加はその成形物の物性
に影響を及ぼすので避けるべきであり、その抗菌力を考
慮して組成物に対し一般に１０％以下、好ましくは０．
５〜６％程度の添加量で充分である。When the metal-containing inorganic compound antibacterial agent carrying the metal salt thus obtained is dried and finely pulverized and mixed with an inorganic or organic dental material composition, an emulsion or an organic solution like the metal or the metal salt itself is obtained. Even if it is dispersed therein, it is possible to obtain a uniformly dispersed material without separation, and the antibacterial activity does not change even by heat molding. Dispersion of the metal inorganic compound antibacterial agent in the dental material composition is desired to be as fine as possible, preferably 5 to 80 μm, preferably 30 μm.
Finely grind around μ and add. The amount added is not particularly limited, but excessive addition to the organic dental material affects the physical properties of the molded article and should be avoided. Generally, in view of its antibacterial activity, it is generally 10% or less, preferably 0%. ．
An addition amount of about 5 to 6% is sufficient.
このようにしてえられた金属有含無機化合物抗菌剤含有
歯科材料組成物は各成分が均一に分散され、加熱によっ
ても抗菌性に変化がなく、特に虫歯菌及びカンジダ菌へ
の抗菌性を長期間保持する上、従来と同様の方法で成形
でき、えられた成形物は従来の成形物と比較し機能的に
変化がみとめられない。The thus obtained dental material composition containing a metal-containing inorganic compound antibacterial agent has each component uniformly dispersed, and the antibacterial property does not change even when heated, and particularly the antibacterial property against caries and candida is prolonged. In addition to holding for a period, it can be molded by the same method as the conventional one, and the obtained molded product has no functional change compared to the conventional molded product.
以下実施例を示して本発明を具体的に説明する。The present invention will be specifically described below with reference to examples.
1)床用レジン モノマー液／ポリマー粉末比 ０．４５ｍｌ／ｇで混和
し、型に入れ、３０kgf/cm2で加圧し、７０℃熱水で１
時間、さらに沸騰水で１時間加熱する。1) Floor resin Monomer liquid / polymer powder ratio 0.45 ml / g were mixed, put in a mold, pressurized at 30 kgf / cm 2 , and heated at 70 ° C. for 1 hour.
Heat for 1 hour with boiling water.
2)コンポジットレジン 3)歯科用セメント 4)根管充填剤 5)ガッタパーチャーポイント 6)人工歯 7)覆髄、根管充填剤 8)抗菌力試験 (1) 実施例(1)〜(6)の組成物はいずれも３．０〜５．
０×１０４のカンジダ菌を４８時間後には１０以下に殺
菌した。2) Composite resin 3) Dental cement 4) Root canal filling agent 5) gutta-perture point 6) artificial teeth 7) Capsule pulp, root canal filling agent 8) Antibacterial activity test (1) The compositions of Examples (1) to (6) were all 3.0 to 5.
0 × 10 4 of Candida was sterilized to 10 or less after 48 hours.
(2) 実施例(1)〜(7)の組成物は以下の抗菌性を示し
た。(2) The compositions of Examples (1) to (7) exhibited the following antibacterial properties.
１）〜７）のいずれも以下のような結果が得られた。The following results were obtained in all of 1) to 7).
又、金属含有無機化合物抗菌剤としてAg、Zn含有ハイド
ロキシアパタイトを用いて実施例１）〜７）の組成物を
作成した場合にも上記と同様の結果が得られた。 Also, when the compositions of Examples 1) to 7) were prepared using Ag and Zn containing hydroxyapatite as the metal-containing inorganic compound antibacterial agent, the same results as above were obtained.
（発明の効果） 本発明による歯科材料組成物は、抗菌性を有するため口
臭、口内炎及び虫歯の発生を抑制し、口腔を衛生的に保
持できる。(Effects of the Invention) Since the dental material composition according to the present invention has antibacterial properties, it can suppress the occurrence of bad breath, stomatitis, and tooth decay, and can keep the oral cavity hygienic.
───────────────────────────────────────────────────── フロントページの続き (56)参考文献 特開 昭50−123766（ＪＰ，Ａ) 特開 昭55−362（ＪＰ，Ａ) 特開 昭59−122410（ＪＰ，Ａ) 特開 昭59−122411（ＪＰ，Ａ) 特開 昭61−227511（ＪＰ，Ａ) 特開 昭62−19506（ＪＰ，Ａ) 特開 昭62−19508（ＪＰ，Ａ) ─────────────────────────────────────────────────── ─── Continuation of the front page (56) References JP-A-50-123766 (JP, A) JP-A-55-362 (JP, A) JP-A-59-122410 (JP, A) JP-A-59- 122411 (JP, A) JP 61-227511 (JP, A) JP 62-19506 (JP, A) JP 62-19508 (JP, A)
Claims (1)
セメント、根管充填剤、ガッタパーチャーポイント、覆
髄根管充填剤及び人工歯よりなる群から選ばれた歯科材
料組成物であって、該組成物が、ゼオライト、フッ石
群、カイリョク石、モレキュラーシーブ、パームチッ
ト、ハイドロキシアパタイト、モンモリロナイト、活性
炭、酸性白土、活性アルミナ、シリカ及びケイ藻土より
なる群から選ばれた無機化合物に、銀、銅及び亜鉛から
選ばれた金属イオンを担持させてえられた金属含有無機
化合物抗菌剤を含有することを特徴とする歯科材料組成
物。1. A dental material composition selected from the group consisting of a floor resin, a composite resin, a dental cement, a root canal filler, a gutta-perture point, a pulp capping root canal filler, and an artificial tooth. The composition is zeolite, fluorite group, gyorekite, molecular sieve, palm chit, hydroxyapatite, montmorillonite, activated carbon, acid clay, activated alumina, silica, and an inorganic compound selected from the group consisting of diatomaceous earth, silver, copper. And a metal-containing inorganic compound antibacterial agent obtained by supporting a metal ion selected from zinc.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63060548A JPH0662379B2 (en) | 1988-03-16 | 1988-03-16 | Dental material composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63060548A JPH0662379B2 (en) | 1988-03-16 | 1988-03-16 | Dental material composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01238508A JPH01238508A (en) | 1989-09-22 |
| JPH0662379B2 true JPH0662379B2 (en) | 1994-08-17 |
Family
ID=13145451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63060548A Expired - Fee Related JPH0662379B2 (en) | 1988-03-16 | 1988-03-16 | Dental material composition |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0662379B2 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01254608A (en) * | 1988-04-04 | 1989-10-11 | Yukiko Hirano | Material for antibacterial base |
| JP2512324B2 (en) * | 1988-11-24 | 1996-07-03 | 株式会社ジーシーデンタルプロダクツ | Dental resin composition |
| JP2690371B2 (en) * | 1989-09-29 | 1997-12-10 | 株式会社クラレ | Dental composition |
| KR940000032B1 (en) * | 1990-10-19 | 1994-01-05 | 주식회사 삼우원적외선 | Disinfectant bioceramic composition |
| US5468489A (en) * | 1991-10-29 | 1995-11-21 | Sangi Co., Ltd. | Dentifrice containing antibacterial material |
| JP2717342B2 (en) * | 1993-01-19 | 1998-02-18 | エルソルプロダクツ 株式会社 | Composite resin for dental material and its antibacterial and sterilizing treatment method |
| US5476881A (en) * | 1993-02-15 | 1995-12-19 | Suh; Kang I. | Antimicrobial composition for manufacturing nipples |
| EP0611564B1 (en) * | 1993-02-19 | 1997-07-30 | Elsol Products Corporation | Composite resin for use in dentistry and method for treating same to provide antimicrobial and microbicidal properties |
| JPH07330532A (en) * | 1994-06-06 | 1995-12-19 | Shiken:Kk | Dental material composition |
| US6267590B1 (en) * | 1999-11-24 | 2001-07-31 | Agion Technologies, Llc | Antimicrobial dental products |
| JP2011132181A (en) * | 2009-12-24 | 2011-07-07 | Jgc Catalysts & Chemicals Ltd | Antibacterial dental composition |
| CN116196222B (en) * | 2023-02-28 | 2025-02-18 | 上海沐良医疗器械有限公司 | Caries preventing additive, caries preventing material, dental diaphragm and invisible appliance |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50123766A (en) * | 1974-02-13 | 1975-09-29 | ||
| JPS55362A (en) * | 1979-03-31 | 1980-01-05 | Yamaga Kenkyusho:Kk | Dental cement |
| JPS59122410A (en) * | 1982-12-28 | 1984-07-14 | Tokuyama Soda Co Ltd | Dental cement composition |
| JPS59122411A (en) * | 1982-12-29 | 1984-07-14 | Tokuyama Soda Co Ltd | Dental cement composition |
| JPS61227511A (en) * | 1985-04-02 | 1986-10-09 | G C Dental Ind Corp | Dental composite resin composition |
| JPS6219506A (en) * | 1985-07-18 | 1987-01-28 | G C Dental Ind Corp | Water-based colloidal composition for preventing dental caries |
| JPS6219508A (en) * | 1985-07-18 | 1987-01-28 | Sankin Kogyo Kk | Root canal filling material for dental use |
-
1988
- 1988-03-16 JP JP63060548A patent/JPH0662379B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01238508A (en) | 1989-09-22 |
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