JPH066527B2 - Hair restorer - Google Patents

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a hair nourishing agent using vitamin P and vitamin C having a protective effect on capillaries.

[0002]

2. Description of the Related Art Speaking of hair nourishing agents, those containing a scalp blood circulation-promoting substance such as capsicum tincture, assembly extract, ginseng extract, nicotinic acid and methyl nicotinate have been known. Further, recently, a hair nourishing agent has been proposed in Japanese Patent Application Laid-Open No. 2-275815, which focuses on the fact that an extract of spruce has an activity inhibiting activity of 5α-reductase, which is an androgen activating enzyme.

[0003]

However, as described above, the conventional hair nourishing agent uses a blood circulation promoting substance or an activity inhibitor of androgen activating enzyme, and has a certain effect per se. In addition, it was insufficient. For this reason,
Development of a further improved hair nourishing agent is expected.

The present invention has been made in view of the above-mentioned conventional circumstances, and it is possible to impart flexibility or elasticity to capillaries under the head of the head to prevent leakage of blood, thereby promoting hair growth. An object is to provide a hair nourishing agent which can

[0005]

The hair nourishing agent provided by the present invention contains vitamin P and vitamin C.

The vitamin P referred to herein is, for example, a mixture of hesperidin, elycdiol and rutin. As a commercially available product, hesperidin, vitamin P or rutin may be used, but rutin is preferred.

The content of vitamin P is 0.01-5%,
It is preferably 0.05 to 2%. The content of vitamin C is 0.01 to 10%, preferably 0.03 to 5
%.

[0008]

The above-mentioned vitamin P and vitamin C impart flexibility or elasticity to the capillaries under the scalp, so that blood leakage in the capillaries is eliminated, and the capillaries operate normally. As a result, hair growth is promoted.

[0009]

【Example】

(Example 1) The hair nourishing agent of Example 1 was prepared by the following formulation. At the time of adjustment, rutin was added to hot alcohol to dissolve it, purified water was added, and finally vitamin C was added. Herperidine 0.3% Pitamine C 0.3% 95% Alcohol 58.0% Purified water 41.4% The obtained hair nourishing agent was tested for the hair growth promoting effect in rats by the following test method. Got

(1) Test Method Ten male ddY rats were selected as test animals, and the abdomen of each was depilated with a depilatory cream, and the depilatory part was applied with the above hair nourishing agent once a day for 14 days.

As a comparative example, 10 rats were applied with 55% aqueous alcohol solution once a day for 14 days in the same manner.

(2) Test Results Table 1 shows the results of the above application test, that is, the hair growth promoting effects of the hair nourishing agent of Example 1 and the 55% alcohol aqueous solution of Comparative Example. The hair growth promoting effect was set in the following 5 grades and evaluated by the average value of 10 rats.

1 No hair growth is observed 2 Hair is growing 3 Hairs are grown 4 Hairs are about half of normal hairs 5 Normal hair condition

[0014]

[Table 1]

As is clear from Table 1, in Example 1, remarkable hair growth was observed from the initial application and a significant hair growth promoting effect was observed during the application period, as compared with Comparative Example.

(Example 2) The hair nourishing agent of Example 2 was prepared according to the following formulation. At the time of adjustment, rutin was added to hot alcohol to dissolve it, purified water was added, and finally vitamin C was added. Rutin 0.3% Pitamine C 0.3% 95% Alcohol 58.0% Purified water 41.4% The obtained hair nourishing agent of Example 2 was tested for its effect on promoting human hair growth by the following test method. The following test results were obtained.

For comparison, a similar test was conducted on the hair nourishing agent of Example 1, and the following results were obtained.

(1) Test method The above-mentioned hair nourishing agent was applied twice a day (morning and evening) for 4 months to the hairline part of the head of 12 male pattern baldness patients who were the test subjects.

(2) Test Results Table 2 shows the results of the coating test. The hair growth promoting effect was set in the following 5 grades, and was shown by the self-evaluation of 12 test subjects. 5 High hair growth strength 4 Raw hair becomes bristle 3 Raw hair expands 2 Hair loss stops 1 Hair growth is not recognized

[0020]

[Table 2]

As is clear from Table 2, a significant hair growth promoting effect is recognized during the application period. In particular, the effect of Example 2 is remarkable. This indicates that rutin is excellent and effective among vitamin P.

(Embodiment 3) Although the hair nourishing agents of Examples 1 and 2 are both liquid, a viscous ointment hair nourishing agent can be obtained by adjusting the following formulation. Vitamin P 0.3% NaOH 0.1% Polyethylene glycol (molecular weight 4000) 5.0% Vitamin C 0.3% Purified water 94.3% That is, the hair nourishing agent of Example 3 dissolves NaOH in a small amount of water. , Vitamin P is added and dissolved therein. After that, it is obtained by adding the remaining water, adding polyethylene glycol, and finally adding vitamin C.

Although the hair growth promoting effect of the hair nourishing agent of Example 3 has not been tested, it can be easily estimated that the same effect will be obtained.

[0024]

As described above, according to the hair nourishing agent of the present invention, since the action of protecting blood capillaries of vitamin P and vitamin C is utilized, hair growth can be promoted.

Claims (1)

[Claims] 1. A hair nourishing agent containing vitamin P and vitamin C.