JPH0669945B2 - Hair dyeing composition - Google Patents

Description

Description: TECHNICAL FIELD The present invention relates to a hair dyeing composition, and more particularly to a composition for dyeing hair to a natural black brown color under mild conditions using melanin.

[Conventional technology]

Hair, especially those currently on the market as permanent oxidative hair dyes for the purpose of dyeing the gray hair of middle-aged and elderly people to black hair,
Mostly, aromatic amines including para-phenylenediamine are polymerized with hydrogen peroxide in the neutral to alkaline region, and the resulting black-brown dye polymer is dyed on the hair. However, paraphenylenediamine, which is frequently used as a starting material, has a possibility of causing allergic dermatitis, although the frequency is not so high. Therefore, with the aim of reducing the risk of developing allergies, and with the recent increase in natural orientation,
Research and development have been carried out on melanin-based hair dyes that dye the resulting melanin pigment on hair by utilizing the melanin-producing mechanism of the living body, and some proposals have already been made.

However, the biggest problem with these hair dyes is how to dye the melanin formed on the hair, and various attempts have been made in this regard. JP53-13
3641 is a melanin precursor to which a ferrous salt, a lead salt, a manganese salt, a cobalt salt, or the like is added to improve the dyeing effect, and without using an enzyme or hydrogen peroxide,
A method of dyeing a natural black hair in one week to one month is shown. In JP-A-53-32132, in order to improve the dyeing property, the hair is pretreated with a reducing agent such as sulfite, further treated with a metal salt, and then dyed with a mixed solution of a melanin precursor and hydrogen peroxide. A method of hairing has been proposed. In addition, JP-A-50-
For 88240, reduce the cystine bond by reducing the hair with dithiothreitol, which is a very strong reducing agent, to improve the permeability to hair, and then apply the precursor solution and tyrosinase mixture solution. , A method of dyeing hair over 80 minutes is shown. However, these all have problems that the operation is complicated and it takes a long time for dyeing, and there is a fear of damage to hair such as the use of heavy metal salts and the use of strong reducing agents.

[Problems to be Solved by the Invention]

The present invention provides fast, simple and strong dyeability without using heavy metal salts, reducing agents or hydrogen peroxide,
Moreover, it is an object of the present invention to provide a hair dye capable of dyeing hair on the scalp and hair under mild conditions.

[Means for Solving the Problems]

According to the present invention, a melanin precursor consisting of L- or DL-serine and pyrocatechol or sodium pyruvate and pyrocatechol and ammonium acetate, a dyeing improving agent consisting of an aromatic amine and an aqueous solution containing a sizing agent are used. There is provided a composition for dyeing hair, which comprises an agent and a second agent containing at least one selected from a β-tyrosinase enzyme solution and a mushroom extract.

As a result of intensive studies, the present inventors have completed the above system as a solution to the above problems. That is, this system is a β-tyrosinase enzyme solution after a solution containing a melanin precursor as a first agent, a dyeing enhancer (melanin carrier) and a paste (protective colloid film-forming substance) is sufficiently penetrated into the hair. And / or a system for applying melanin in the hair in a short time and strongly dyeing it by applying mushroom extract and contacting with air sufficiently.

The melanin precursor is a biogenic essential amino acid,
It is particularly desirable to use a system of L-serine and pyrocatechol, which has a moisturizing effect and is easily soluble in water.

[Action]

In particular, the greatest feature of the present invention is the addition of a melanin carrier selected from aromatic amines for improving the dyeing property. Although melanin hardly dyes hair by itself, dyeing property is drastically improved by adding a trace amount of aromatic amine as a melanin carrier, preferably paraphenylenediamine. It is presumed that this is because the amine taken in during the melanin production process is dyed by forming a bond with the carboxyl group of the hair protein. Further, the addition of a small amount of resorcin also contributes to the improvement of the dyeing property. Further, the polymer added as a sizing agent has a function of wrapping the dyed melanin in a colloid film, and further strengthening the fixation to the hair.

In the composition of the present invention, the amount of the aromatic amine added as a dyeing improver is 1/10 or less compared to the amount contained in the conventional oxidative hair dye, so that the risk of developing allergies is extremely small. I can say. Serine, which is used as a precursor, is an essential amino acid in the body and is NMF (natural moisturizing factor).
Since it is also an important ingredient of, the safety can be said to be extremely high. Further, in the present invention, since hydrogen peroxide is not used for melanization and an enzyme is used, the treatment pH is optimal in the neutral region, and the treatment temperature shows the best activity from room temperature to 40 ° C. Therefore, it can be said that since the reaction proceeds under mild conditions, irritation and damage to the scalp and hair are extremely small.

Next, the preferable constitution of the composition of the present invention and its use will be explained. A system selected from the system of L- or DL-serine and pyrocatechol and the system of sodium pyruvate, pyrocatechol and ammonium acetate as the melanin precursor, preferably a solution in which the system of L- or DL-serine and pyrocatechol is dissolved (preferably , 0.2-5%), o-, m- or p-aminophenol (abbreviated as OAP, MAP, PAP, respectively), p-phenylenediamine (PPDA), 4,4'-diaminodiphenylamine (DADPA), p- Addition of one or two aromatic amines such as methylaminophenol (PMAP) and 2,5-diaminotoluene (DAT) (desirably including p-phenylenediamine), preferably in an amount of 0.05 to 0.2% by weight. Then, a small amount of resorcin is added, and the pH is adjusted to preferably 6 to 8, more preferably 7.5 with ammonium hydrogencarbonate or aqueous ammonia. further,
By adding a sizing agent polymer such as hydroxyethyl cellulose (HEC), carboxymethyl cellulose (CMC), sodium alginate (ArgNa) or polyethylene glycol (PEG), preferably in an amount of 0.2 to 5.0% by weight, a viscosity of 200 to 300 cp is obtained. Apply hair to the adjusted liquid (1st agent)
Soak for 15 minutes. Then, sprinkle with β-tyrosinase enzyme solution (0.05-0.1% solution) or mushroom extract (second agent) dissolved immediately before use in a phosphate buffer of pH 6 to 8, more preferably pH 7.5, and sprinkle as much as possible. Brush the hair to improve the contact with the air,
After dyeing for 15 to 45 minutes, wash in hot water without using shampoo. Due to the gradual effect of the enzyme, better dyeability can be obtained by washing with shampoo the next day.

The mushroom extract can be obtained, for example, by crushing mushrooms, adding water and shaking well.

〔Example〕

 Next, the present invention will be further described with reference to examples.

Example 1 1st agent L-serine 2g Pyrocatechol 2g Paraphenylenediamine 0.2g Resinicin 0.2g Ammonium hydrogencarbonate 0.4g Hydroxyethyl cellulose 0.5g Purified water is added to make 100 ml (pH 7.5).

Second agent β-tyrosinase 0.1 g Phosphate buffer (pH 7.5) 100 ml (dissolved immediately before use) 50 to 80 ml of the first agent was applied to the hair and left at room temperature for 15 minutes to allow it to fully penetrate into the hair. After that, 20 to 30 ml of the enzyme solution of the second agent is sprinkled on the whole hair, and the whole hair is loosened to make sufficient contact with air, left for 15 to 45 minutes, and then rinsed with warm water. By performing shampoo washing the next day without immediately performing shampoo washing, better dyeing property can be obtained.

By dyeing hair by the above-mentioned method, white hair is covered and a durable natural brown hair color is obtained. Furthermore, using a test hair bundle, the hair dyed by the above method was put into a shampoo solution (10%) and an acidic artificial sweat (pH 4.
5) Even when immersed in alkaline artificial sweat (pH 7.9) three times each in a constant temperature bath at 45 ° C for a total of 50 hours, there is little discoloration and durability especially against alkaline sweat. It was great.

Example 2 First agent L-serine 2g Pyrocatechol 1g Paraphenylenediamine 0.2g Resorcin 0.2g Ammonium hydrogencarbonate 0.4g Carboxymethylcellulose 1.0g Purified water is added to make 100 ml (pH 7.5).

Second agent β-tyrosinase 0.1 g Phosphate buffer (pH 7.5) 100 ml (dissolved immediately before use) Hair dyeing was performed in the same manner as in Example 1. A durable, natural dark brown hair color is obtained.

Example 3 First agent Sodium pyruvate 2g Pyrocatechol 2g Ammonium acetate 1g Paraphenylenediamine 0.2g Resorcinol 0.1g Ammonium bicarbonate 0.4g Sodium alginate 1g Purified water is added to make 100 ml (pH 7.2).

Second agent β-tyrosinase 0.1 g Phosphate buffer (pH 6.8) 100 ml (dissolved immediately before use) The method for dyeing hair is the same as in Example 1. Dyes in a durable natural dark brown color.

Example 4 1st agent DL-serine 2g Pyrocatechol 1g p-methylaminophenol 0.1g 4,4'-diaminodiphenylamine 0.1g Ammonium hydrogencarbonate 0.4g Sodium alginate 1g Purified water was added to 100 ml (pH 7.0). To do.

Second agent β-tyrosinase 0.1 g Phosphate buffer (pH 6.8) 100 ml (dissolved immediately before use) The method for dyeing hair is the same as in Example 1. Hair is dyed in natural gray.

Example 5 First agent DL-serine 2g Pyrocatechol 2g p- or m-aminophenol 0.1g p-Phenylenediamine 0.1g Ammonium hydrogencarbonate 0.4g Resorcinol 0.1g Hydroxyethylcellulose 1g Purified water added 100ml (pH 7.2) And

Second agent β-tyrosinase 0.1 g Phosphate buffer (pH 6.8) 100 ml (dissolved immediately before use) The method for dyeing hair is the same as in Example 1. It is dyed in a natural blackish brown with a slight gray tinge.

Example 6 First agent DL-serine 3 g Pyrocatechol 1.5 g 4,4'-Diaminodiphenylamine 0.1 g Paraphenylenediamine 0.2 g Resorcin 0.2 g Ammonium hydrogencarbonate 0.4 g Sodium alginate 0.5 g Purified water was added to 100 ml (pH 7. 3)

Second agent β-tyrosinase 0.1 g Phosphate buffer (pH 6.8) 100 ml (dissolved immediately before use) Hair is dyed by the same method as in Example 1. It was dyed in a natural blackish brown with a slight grey, and there was very little discoloration or fading over a long period of time.

Example 7 First agent DL-serine 2 g Pyrocatechol 2 g Paraphenylenediamine 0.2 g Resorcin 0.2 g Ammonium bicarbonate 0.4 g Carboxymethyl cellulose 1.0 g Purified water is added to make 100 ml (pH 6.8).

Second agent mushroom extract (dissolved immediately before use) Hair dyeing was performed in the same manner as in Example 1. A durable, natural dark brown hair color is obtained.

The mushroom extract used above is as follows.

After crushing 100 g of mushrooms with a mixer, distilled water 10
Pour 0 ml, shake well, filter with a glass filter, and lyophilize the filtrate to give a powder. This powder
It is used by dissolving it in a pH 7 phosphate buffer to a concentration of 1%.

Hair dyeing conditions for several systems, including the above examples,
The dyeability and the like are summarized in Table 1. A comparative example is also given.

[Advantages of the Invention] As described above, by adding a trace amount of an aromatic amine as a melanin carrier and a colloid film-forming polymer as a sizing agent to a melanin precursor, as compared with the conventional method, it is very simple, quick and strong dyeing. Hair became possible. Hair dyed by this method is resistant to sweat and shampoo, and it is possible to maintain a natural black-brown or maroon hair color with little discoloration or fading. Further, it is predicted that the possibility of developing allergies is extremely low as compared with the oxidative hair dye currently on the market.

Claims (1)

[Claims] 1. A melanin precursor comprising L- or DL-serine and pyrocatechol or sodium pyruvate and pyrocatechol and ammonium acetate, a dyeing improving agent comprising an aromatic amine and an aqueous solution containing a sizing agent.
A composition for dyeing hair, which comprises an agent and a second agent containing at least one selected from a β-tyrosinase enzyme solution and a mushroom extract.