JPH07110279B2 - Small animal restraint system - Google Patents
Small animal restraint systemInfo
- Publication number
- JPH07110279B2 JPH07110279B2 JP21212389A JP21212389A JPH07110279B2 JP H07110279 B2 JPH07110279 B2 JP H07110279B2 JP 21212389 A JP21212389 A JP 21212389A JP 21212389 A JP21212389 A JP 21212389A JP H07110279 B2 JPH07110279 B2 JP H07110279B2
- Authority
- JP
- Japan
- Prior art keywords
- subject
- pedestal
- limb
- base
- small animals
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241001465754 Metazoa Species 0.000 title claims description 12
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 18
- 230000000452 restraining effect Effects 0.000 claims description 5
- 210000003414 extremity Anatomy 0.000 description 16
- 239000000463 material Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 241000700159 Rattus Species 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 210000003141 lower extremity Anatomy 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 229930182556 Polyacetal Natural products 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 229920006324 polyoxymethylene Polymers 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 230000037237 body shape Effects 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000003194 forelimb Anatomy 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Landscapes
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Description
【発明の詳細な説明】 （イ） 産業上の利用分野 本発明はラット等の小動物用保定装置に関し、特に薬効
解析のための心電図記録に好適な小動物用保定装置に関
する。The present invention relates to a restraint device for small animals such as rats, and particularly to a restraint device for small animals suitable for recording an electrocardiogram for drug efficacy analysis.
（ロ） 従来の技術 薬効解析のために行われる被検体の心電図記録では無麻
酔の被検体を安定に保定する必要が生ずる。しかし、意
思伝達が困難なラット等の小動物の心電図記録にあって
は、保定作業自体が繁雑であるばかりか被検体を安定に
保つことはさらに困難であって、信頼性が高い心電図記
録を行うにはかなりの熟練、多数の人手、さらには時間
が要求されている。(B) Conventional technology In electrocardiographic recording of a subject performed for drug efficacy analysis, it is necessary to stably retain an unanesthetized subject. However, when recording electrocardiograms of small animals such as rats that are difficult to communicate with, not only is the retention work complicated, but it is more difficult to keep the subject stable, and reliable electrocardiographic recording is performed. Requires a great deal of skill, a lot of manpower, and even time.
以下、従来の小動物の保定手法の中では簡便であって、
比較的信頼性の高い心電図記録が行えるとされている手
法を第２図を参照して説明する。The following is a simple method among the conventional methods for retaining small animals,
A method which is said to be capable of relatively reliable electrocardiographic recording will be described with reference to FIG.
同図はその口径が被検体の大きさに略等しく形成された
筒状保定具（21）を示す。その材料は透明若しくはネッ
トであり、所定位置に４つの四肢引出孔（21a）が形成
されている。図示するように、被検体（20）を保定具
（21）の筒状部に押し込むと共に被検体（20）の四肢を
引出孔（21a）から引き出して、さらに必要あればテー
プにて所定部位に固定することによって被検体（20）の
保定が行われる。The figure shows a tubular retainer (21) having a diameter substantially equal to the size of the subject. The material is transparent or net, and four limb extraction holes (21 a ) are formed at predetermined positions. As shown in the figure, push the subject (20) into the tubular part of the retainer (21), pull out the limbs of the subject (20) from the pull-out holes (21 a ), and use tape if necessary. The subject (20) is retained by fixing the subject (20).
既に明らかなように、この保定具に被検体の拘束能力を
求めるときには被検体の四肢の引き出し作業が極めて困
難となる。また、保定具（21）の材料には被検体（20）
を拘束する剛性と、被検体（20）の四肢を引き出す際に
必要な柔軟性という相反する特性が要求される。As is already clear, when the restraint ability of the subject is demanded by this restraint, the work of pulling out the four limbs of the subject becomes extremely difficult. The material of the retainer (21) is the subject (20).
The contradictory characteristics of rigidity for restraining the subject and flexibility necessary for pulling out the extremities of the subject (20) are required.
（ハ） 発明が解決しようとする課題 上記した保定具にあっては、被検体の行動を拘束し得る
剛性と被検体の四肢を引き出す際に必要な柔軟性とを備
える材料の選定が困難である。(C) Problem to be Solved by the Invention In the above-described retainer, it is difficult to select a material having rigidity that can restrain the behavior of the subject and flexibility necessary for pulling out the limbs of the subject. is there.
また、従来の保定具あるいは保定手法は全般に被検体の
拘束のみに主眼が置かれており、拘束された被検体の行
動様式を考慮するものではなかった。このため、拘束さ
れた被検体は疲弊するまで脱出行動を止めようとはせ
ず、信頼性が高い心電図記録を速やかに行うことができ
なかった。Further, the conventional restraint devices or restraint methods generally focus only on restraint of the subject, and do not consider the behavior pattern of the restrained subject. For this reason, the restrained subject did not try to stop the escape behavior until he was exhausted, and it was not possible to quickly perform reliable electrocardiographic recording.
本発明は上記した従来手法に存する課題の解決を目的と
するものであって、さらに付記するならば、被検体の脱
出行動時の動作支点のみを規制すると共に動作力点をフ
リーとすることにより、被検体に恐怖を与えることのな
い、もって速やかに信頼性ある心電図記録等を行うこと
ができる保定装置を提供することを目的とする。The present invention is intended to solve the problems existing in the above-mentioned conventional method, and if further noted, by restricting only the operating fulcrum at the time of escape behavior of the subject and freeing the operating force point, An object of the present invention is to provide a restraint device that does not scare a subject and can promptly perform reliable electrocardiographic recording and the like.
（ニ） 課題を解決するための手段 本発明は、基台と、被検体の四肢の基部位置の１つを規
制する１対の四肢規制杆を備え、前記基台の所定部位に
係合され、かつ被検体の四肢幅以下の幅を有する架台
と、この架台の所定部位に一端が回動可能に軸支され
て、被検体を架台との間に挟持する略コ字形状の把持部
と、前記架台に摺動可能に係合される３対の四肢規制杆
から構成される。(D) Means for Solving the Problems The present invention comprises a base and a pair of limb control rods for controlling one of the base positions of the four limbs of the subject, and is engaged with a predetermined portion of the base. A pedestal having a width equal to or less than the limb width of the subject, and a substantially U-shaped gripping portion having one end rotatably supported at a predetermined portion of the pedestal and holding the subject between the pedestal and the pedestal. , Three pairs of limb control rods slidably engaged with the mount.
（ホ） 作用 上記構成は、被検体の動作支点となる四肢の基部の移動
のみを規制し、動作力点となる四肢先端部を自由垂下さ
せることによって、被検体を徒らに拘束することなく、
安定に保定するよう作用する。また、各種体型の被検体
に適合するよう作用する。(E) Action The above configuration restricts only the movement of the base of the limb, which is the fulcrum of movement of the subject, and freely suspends the tip of the limb, which is the motive force of the subject, without restraining the subject.
It acts to hold it stable. In addition, it acts so as to adapt to various body types of subjects.
（ヘ） 実施例 以下、実施例の側面構造を示す第１図（Ａ）および正面
構造を示す第１図（Ｂ）を参照して本発明を説明する。(F) Example Hereinafter, the present invention will be described with reference to FIG. 1 (A) showing a side structure and FIG. 1 (B) showing a front structure of the example.
本発明の小動物用保定装置は概ね、ステンレス鋼等の耐
薬品材料により形成される基台（１）、ポリアセタール
樹脂等により形成される架台（２）、同じくポリアセタ
ール樹脂等により形成される把持部（３）、および被検
体の四肢基部を挟持する４対の四肢規制杆（以下、単に
規制杆と称する）（2c）（4b）（5b）（6b）から構成さ
れる。The restraint device for small animals of the present invention generally comprises a base (1) formed of a chemical resistant material such as stainless steel, a pedestal (2) formed of polyacetal resin or the like, and a grip portion (also formed of polyacetal resin or the like). 3) and four pairs of limb control rods (hereinafter, simply referred to as control rods) (2 c ), (4 b ), (5 b ), and (6 b ) that clamp the limb base of the subject.
基台（１）は本装置を安定に設置できる底面積を有し、
漏出薬物あるいは汚物を収容する容器部（1a）と架台
（２）を回動可能に軸支するための軸受部（1b）（1c）
からなり、一方の軸受部（1b）には適宜の指針（1d）が
形成または固着されている。The base (1) has a bottom area that enables stable installation of this device,
Container portion for accommodating leakage drug or waste (1 a) and the bearing portion for rotatably supported the pedestal (2) (1 b) ( 1 c)
The bearing (1 b ) on one side is formed or fixed with an appropriate pointer (1 d ).
また、架台（２）の平板部（2a）の幅は被検体の四肢幅
以下であって、被検体を伏臥させるときにその四肢が平
板部（2a）の外側に自由垂下するようになされている。
なお、発明者等による多数のサンプルの計測によって、
ラットの四肢幅がその体型によらず略一定であることが
知られている。さらに、平板部（2a）の中央部には破線
で示す長溝（2f）が形成され、これが被検体の竜骨（図
示しない）の収容溝となって被検体を正しく伏臥させる
ことができるようになされている。さらにまた、前記指
針（1d）に対応する位置にスケール（2b）が固着され、
所定位置に１対の規制杆（2c）が開脚固着されている
（第１図（Ｂ）の参照番号（6b）を付した部材の形状を
参照されたい）。In addition, the width of the flat plate portion (2 a ) of the gantry (2) is less than or equal to the limb width of the subject, so that the limbs hang freely outside the flat plate portion (2 a ) when the subject is prone. Has been done.
In addition, by the measurement of many samples by the inventors,
It is known that the width of four limbs of a rat is almost constant regardless of its body shape. Further, a long groove (2 f ) shown by a broken line is formed in the central portion of the flat plate portion (2 a ) so as to serve as a receiving groove for the keel (not shown) of the subject so that the subject can be properly prone. Has been done. Furthermore, the scale (2 b ) is fixed to the position corresponding to the pointer (1 d ),
A pair of regulating rods (2 c ) are fixed to the predetermined positions by open legs (see the shape of the member with reference numeral (6 b ) in FIG. 1 (B)).
把持部（３）は必要に応じてその下面にパッドが付設さ
れる水平部（3a）と、この水平部（3a）の押圧角度を適
度のものとする立ち上がり部（3b）（3d）からなり、略
コ字形状を呈する。そして、各種体型の被検体に適合可
能なように、一方の立ち上がり部（3b）にはその回動中
心に架台（２）の平板部（2a）に設けられた軸（2d）と
係合する３連の係合孔（3c）が形成され、他方の立ち上
がり部（3d）にはガイド孔となるＵ字形状の切り欠き部
（3e）が形成されている。図示されていないが、切り欠
き部（3e）を所望の位置で固定する機構が付設される。The gripping part (3) has a horizontal part ( 3a ) to which a pad is attached on the lower surface thereof as necessary, and a rising part ( 3b ) ( 3b ) which makes the pressing angle of the horizontal part ( 3a ) moderate. It consists of d ) and has an approximately U-shape. Then, in order to be able to adapt to subjects of various body types, a shaft (2 d ) provided on the flat plate part (2 a ) of the pedestal (2) is provided at the rotation center of the one rising part (3 b ). triplicate engagement hole to be engaged (3 c) is formed, the other raised portion (3 d) cut-out of a U-shape with a guide hole (3 e) is formed. Although not shown, a mechanism for fixing the notch (3 e ) at a desired position is additionally provided.
さらに、他の３対の規制杆のうち少なくとも１対の規制
杆、例えば（4b）は第１図（Ｂ）に示すように水平方向
に延在されている。また、何れも適宜の摺動機構（4a）
（5a）（6a）と所定位置にて固定する機構（4c）（5c）
（6c）を備え、各種体型の被検体の保定に適合するよう
なされている。Further, among the other three pairs of the control rods, at least one pair of the control rods, for example (4 b ), extends horizontally as shown in FIG. 1 (B). In addition, any sliding mechanism (4 a )
(5 a) mechanism for fixing at (6 a) and a predetermined position (4 c) (5 c)
Equipped with (6 c ), it is adapted to retain subjects of various body types.
次に、上記のように構成される実施例の使用方法を説明
する。Next, a method of using the embodiment configured as described above will be described.
被検体の適宜箇所を把持し、被検体の後肢が架台（２）
の平板部（2a）を跨ぐようにして、その後肢基部を固定
規制杆（2c）に当接させる。そこで、摺動規制杆（4b）
の位置を調節、固定することによって被検体の後肢基部
位置が規制される。さらに、被検体を平板部（2a）に伏
臥させた後、摺動規制杆（5b）、（6b）の順に位置を調
節、固定すると、前肢の基部位置が固定される。この
際、平板部（2a）に被検体の竜骨を収容する長溝（2f）
が形成されているため、被検体はこれに誘導されるよう
に自然な姿勢となって、短時間のうちに安定状態とな
る。その後、把持部（３）を回動して、適宜の押圧力に
て被検体を押圧固定し、さらに機構（７）によって被検
体の尾が固定されて保定が完了する。Hold the subject at an appropriate point and place the subject's hind limb on the cradle (2).
Straddle the flat plate part ( 2a ) of the above, and bring the hind limb base into contact with the fixed control rod ( 2c ). Therefore, the sliding control rod (4 b )
The position of the hind limb base of the subject is regulated by adjusting and fixing the position. Further, after the subject is laid down on the flat plate portion (2 a ), the positions of the slide regulating rods (5 b ) and (6 b ) are adjusted and fixed in this order, whereby the base position of the forelimb is fixed. At this time, a long groove (2 f ) for accommodating the keel of the subject in the flat plate portion (2 a )
Is formed, the subject takes a natural posture so as to be guided by it, and becomes stable in a short time. After that, the gripping part (3) is rotated to press and fix the subject with an appropriate pressing force, and the tail of the subject is fixed by the mechanism (7) to complete the retention.
この他、本発明の保定装置は架台（２）が回動可能に構
成されており、さらにその角度を読み取る指針（1d）と
スケール（2b）を備えており、心電図記録中の被検体に
対する投薬、注射を容易に行うことができる。また、あ
る種の被検体においては、例えば90度横臥位時に特に良
好な心電図記録が行えることが知られているが、本発明
の保定装置は心電図記録中の体位変更も可能である。In addition, in the restraint device of the present invention, the pedestal (2) is configured to be rotatable, and further provided with a pointer (1 d ) for reading the angle and a scale (2 b ), the subject being recorded in the electrocardiogram. Can be easily administered and injected. Further, it is known that particularly good electrocardiographic recording can be performed in a certain type of subject, for example, in a 90-degree recumbent position, but the restraint device of the present invention can also change the body position during electrocardiographic recording.
（ト） 発明の効果 以上述べたように本発明の小動物用保定装置は、 （１） 被検体を徒らに拘束することがないため、速や
かに安定状態が得られる。(G) Effect of the Invention As described above, the device for restraining small animals of the present invention (1) does not restrain the subject from being unnecessarily restrained, so that a stable state can be quickly obtained.
（２） 保定操作が簡便であって、１人操作が可能であ
る。(2) Restoration operation is simple and can be operated by one person.
（３） 各種体型の被検体に対応可能である。(3) It is possible to deal with subjects of various body types.
（４） 架台が回動するため、心電図記録中の被検体に
対する投薬、注射が容易となる等、顕著な効果を奏す
る。(4) Since the gantry is rotated, remarkable effects such as easy administration and injection of a subject during recording of an electrocardiogram can be achieved.
第１図（Ａ）および（Ｂ）は本発明の実施例を説明する
それぞれ側面図、正面図、 第２図は従来の小動物保定具を説明する図である。 （１）……基台、（1a）……容器部、（1d）……指針、
（２）……架台、（2a）……平板部、（2b）……スケー
ル、（2c）……固定規制杆、（2f）……長溝、（３）…
…把持部、（4b）（5b）（6b）……摺動規制杆、（７）
……尾固定具。1 (A) and 1 (B) are side views and front views, respectively, for explaining an embodiment of the present invention, and FIG. 2 is a view for explaining a conventional small animal retainer. (1) …… base, (1 a ) …… container part, (1 d ) …… pointer,
(2) …… Stand, (2 a ) …… Flat part, (2 b ) …… Scale, (2 c ) …… Fixed control rod, (2 f ) …… Long groove, (3)…
… Gripping part, (4 b ) (5 b ) (6 b ) …… Sliding control rod, (7)
...... Tail fixing tool.
Claims (4)
制杆を備え、前記基台の所定部位に係合され、かつ被検
体の四肢幅以下の幅を有する架台と、 この架台の所定部位に一端が回動可能に軸支されて、被
検体を架台との間に挟持する略コ字形状の把持部と、 前記架台に摺動可能に係合される３対の四肢規制杆から
構成される小動物用保定装置。1. A base and a pair of limb control rods for controlling one of the base positions of the limbs of the subject, the limbs being engaged with a predetermined portion of the base and having a limb width equal to or less than the limb width of the subject. A pedestal having a width, a substantially U-shaped gripping part having one end rotatably supported at a predetermined portion of the pedestal to clamp the subject between the pedestal and the pedestal, and a slidable engaging part. A small animal restraint system consisting of three pairs of limb control rods to be combined.
の水平方向に延在され、他の四肢規制杆は装置の垂直方
向に、かつ開脚して係合されることを特徴とする請求項
１記載の小動物用保定装置。2. At least one of the four pairs of limb restraining rods extends in the horizontal direction of the device, and the other limb restraining rods engage in the vertical direction of the device and openly. The restraint device for small animals according to claim 1.
ることを特徴とする請求項１記載の小動物用保定装置。3. The restraint device for small animals according to claim 1, wherein the pedestal is rotatably supported by a predetermined portion of the base.
れることを特徴とする請求項１記載の小動物用保定装
置。4. The restraint device for small animals according to claim 1, wherein a long groove is formed in an upper surface of the pedestal in a longitudinal direction thereof.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21212389A JPH07110279B2 (en) | 1989-08-19 | 1989-08-19 | Small animal restraint system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21212389A JPH07110279B2 (en) | 1989-08-19 | 1989-08-19 | Small animal restraint system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0377552A JPH0377552A (en) | 1991-04-03 |
| JPH07110279B2 true JPH07110279B2 (en) | 1995-11-29 |
Family
ID=16617264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP21212389A Expired - Lifetime JPH07110279B2 (en) | 1989-08-19 | 1989-08-19 | Small animal restraint system |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH07110279B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014014085A1 (en) * | 2012-07-20 | 2014-01-23 | Ｋｂセーレン株式会社 | Animal retainer |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8078256B2 (en) | 2002-10-10 | 2011-12-13 | Visualsonics Inc. | Integrated multi-rail imaging system |
| JP5846862B2 (en) * | 2011-11-07 | 2016-01-20 | 日本メジフィジックス株式会社 | Small animal restraint |
-
1989
- 1989-08-19 JP JP21212389A patent/JPH07110279B2/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014014085A1 (en) * | 2012-07-20 | 2014-01-23 | Ｋｂセーレン株式会社 | Animal retainer |
| JPWO2014014085A1 (en) * | 2012-07-20 | 2016-07-07 | Ｋｂセーレン株式会社 | Animal restraint |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0377552A (en) | 1991-04-03 |
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