JPH0818962B2 - Cosmetics - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial field of application] The present invention is characterized in that carboxymethyl chitin, which is a water-soluble chitin compound, and natural mucopolysaccharide are blended as cosmetic ingredients, and for the skin, It is an object of the present invention to provide a cosmetic which has good spreadability, is moist, smooth, and has a feeling of use, is less sticky, has good compatibility with the skin, and has a long-lasting moisturizing effect.

[Conventional technology]

Conventionally, in order to have an excellent moisturizing effect in cosmetics and to give a moist feel when used, various moisturizers and seeds were mixed with a large amount of water-soluble polyhydric alcohol, but moisturized. When trying to emphasize the feeling of use, it tended to be sticky at the time of application and poorly fit into the skin. Among the water-soluble polyhydric alcohols, propylene glycol and polyethylene glycol having a molecular weight of 200 to 400 are preferable because they spread smoothly on the skin during use, but there are concerns about safety (allergenicity). It was leaning back and had restrictions on its use.

[Problems to be solved by the invention]

In view of these circumstances, the present inventor has improved the above-mentioned drawbacks of the prior art, has good safety, has a moist, smooth and rich feel, is not sticky at the time of application, and is well fit to the skin, As a result of intensive studies to obtain a cosmetic having a long-lasting moisturizing effect, it was found that the aforementioned object can be achieved by combining carboxymethyl chitin and mucopolysaccharide in combination, and the present invention is completed based on this finding. Came to.

[Means for solving problems]

That is, the present invention is a cosmetic containing carboxymethyl chitin and one or more mucopolysaccharides.

 Hereinafter, the configuration of the present invention will be described in detail.

Carboxymethyl chitin used in the present invention is 6 of chitin.
A hydroxyl group is carboxymethylated to be water-soluble.

A method for producing this carboxymethyl chitin is disclosed in
As described in 59-106409 et al., A powdered product of a commercially available chitin grinder is infiltrated into a 42% sodium hydroxide solution, left under reduced pressure for about 8 hours and then left at room temperature under normal pressure for 2 days and nights. After that, while cooling to 0 ° C or lower using an occlusive agent,
Add fine ice with slow stirring. Next, 4M sodium monochloroacetate is added little by little, stirring is continued overnight at room temperature, and after completion of the reaction, dialyzing in running water for 3 days or longer using a cellophane membrane. Prolonging this dialysis time is more preferable because a low amount of impurities is removed. After dialysis,
The precipitated insoluble matter was removed by filtration, and the filtrate was concentrated under reduced pressure.
Lyophilize to obtain white powdery carboxymethyl chitin.

When actually used in the production of cosmetics, an aqueous solution of carboxymethyl chitin before concentration under reduced pressure may be added.

The content of carboxymethyl chitin in cosmetics is preferably 0.001 to 5% by weight based on the total amount of the cosmetics, but it is 0.00 because it does not have a harmful effect such as moistness and stickiness.
A 5 to 1 wt% formulation is particularly preferred.

The mucopolysaccharides used in the present invention include hyaluronic acid, chondroitin-4-sulfate, chondroitin-6-sulfate, dextran sulfate, dermatan sulfate, keratan sulfate, heparin, and salts thereof, and one or two of them are used. At least one species is selected.

The blending amount is selected within the range of 0.001 to 5% by weight based on the total amount of cosmetics. If it is less than 0.001%, the effect of the present invention is not impaired, but the moisturizing effect is weak, and if it exceeds 5%, the solubility becomes poor and sticky.

The mixing ratio of carboxymethyl chitin and mucopolysaccharide is preferably 100/1 to 1/50, and particularly preferably 10/1 to 1/5 in weight%.

In the cosmetic of the present invention, in addition to the above essential components, if necessary, depending on the type of cosmetic, powder, pigment, oil,
Moisturizer, surfactant, antioxidant, thickener, organic solvent,
Ingredients usually used in cosmetics, such as a plasticizer, an antiseptic / antifungal agent, an amino acid, and a fragrance, can be appropriately added within a range not impairing the effects of the present invention. The cosmetic composition of the present invention may have any dosage form, such as a solution system, a solubilization system, an emulsion system, a powder dispersion system, a water-oil two-layer system, a water-oil-powder three-layer system, or the like. I do not care.

Further, the application of the cosmetics of the present invention is also arbitrary, such as a lotion,
Facial cosmetics such as emulsions, creams and packs, hair cosmetics such as hair tonics, hair creams, shampoos and hair rinses, makeup cosmetics such as foundations, lipsticks and eye shadows, body cosmetics, cleansing foams, etc. It can be used for cosmetics and the like.

〔The invention's effect〕

The cosmetic of the present invention has good spreadability on the skin, has a moist, smooth, and rich texture, is less sticky, has good compatibility with the skin, and has a long-lasting moisturizing effect. Is to provide.

〔Example〕

Next, the effects of the combination of carboxymethyl chitin and mucopolysaccharide will be described in more detail with reference to Examples and Comparative Examples. The effect was measured by the following evaluation method.

<Evaluation of usability> By actually using the sample prepared by 10 specialist panels,
A sensory test was performed. Evaluation items are smoothness, spread to the skin,
The seven items are body, familiarity to the skin, moisturizing feeling, non-greasiness, and lasting moisturizing skin 2 hours after application.

 The evaluation results will be expressed as follows.

⊚: 8 or more out of 10 answered that they were good.

○: 6 or more out of 10 answered that they were good.

Δ: 4 or more out of 10 answered that they were good.

×: Less than 4 out of 10 respondents answered good.

(Production method) ~ was dissolved by stirring at room temperature, and then dissolved in was added, and mixed by stirring to obtain a lotion.

(Production method) is heated to 80 ° C and dissolved. On the other hand, was heated to 70 ° C. and dissolved, and after adding and stirring to the above, the emulsion particles were homogenized with a homomixer and cooled to 30 ° C. with a cooler to obtain a cream.

(Test evaluation method) Moisture retention: 40 g of sample in a glass bottle (diameter 4.3 cm, height 3.5 c
m), and keep it open for 1 month in a constant temperature bath at 37 ° C and 50% humidity. Obtain the amount of water loss from the weight change after storage,
It was used as an index of moisturizing property. The smaller the number, the higher the moisturizing property.

Example 9 Foundation (wt%) A Cetanol 3.5 Deodorized lanolin 4 Jojoba oil 5 Vaseline 2 Squalane 6 Glycerin fatty acid ester 2.5 POE (60) Hydrogenated castor oil 1.5 POE (25) Cetyl ether 1 Propylparaben 0.3 Perfume 0.2 B Glycerin 3 Propylene glycol 8 Formulated powder 12 Sodium chondroitin sulfate 0.5 Sodium hyaluronate 0.3 Carboxymethyl chitin 0.3 Purified water to 100 (Production method) The raw materials of the oil phase part belonging to A and the raw material of the water phase part belonging to B were each heated to 70 ° C and completely dissolved. After that, the oil phase part is mixed with the water phase part and emulsified by an emulsifying machine. The emulsion was cooled with a heat exchanger to a final temperature of 30 ° C to obtain a foundation.

Example 10 Emollient lotion (% by weight) A Liquid paraffin 10 Squalane 1 Vaseline 2 Sorbitan sesquioleate 0.9 Polyoxyethylene oleyl ether 1.2 B Purified water 77.2 Glycerin 3 Ethanol 3 Carboxyvinyl polymer 0.2 Potassium hydroxide 0.1 Sodium hyaluronate 0.1 Dextran Sodium sulfate 0.1 Carboxymethyl chitin 1.0 Preservative 0.1 Perfume 0.1 (Production method) According to Example 9.

Example 11 Pack (% by weight) A Purified water Residual dipropylene glycol 5 Polyethylene glycol (molecular weight 4000) 2 Polyvinyl alcohol (polymerization degree 2000, saponification degree 87%) 14
Sodium hyaluronate 0.01 Carboxymethyl chitin 0.5 B Ethanol 10 Perfume 0.1 Preservative 0.1 (Production method) Part A is mixed and dissolved, and after dissolution, part B is added and dissolved by stirring and mixing. After cooling to room temperature, a pack was obtained.

 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Reiji Miyahara 1050 Shinba-cho, Kohoku-ku, Yokohama-shi, Kanagawa Examiner, Shiseido Research Institute Co., Ltd. Mika Kagawa (56) References JP-A-63-230617 (JP, Sho 63-230617) A) JP-A-63-230616 (JP, A) JP-A-63-230615 (JP, A) JP-A-59-106409 (JP, A)

Claims (1)

[Claims] 1. A cosmetic comprising carboxymethyl chitin and one or more mucopolysaccharides.