JPH089526B2 - Cosmetics - Google Patents

Description

TECHNICAL FIELD The present invention relates to a cosmetic containing an acidic amino acid, a basic amino acid, and an amino acid salt. For more information,
The present invention relates to a cosmetic product which can easily adjust the pH by blending an acidic amino acid, a basic amino acid and an amino acid salt.

[Prior Art] Conventionally, a buffer solution is known to have a buffering effect in a specific pH range by using a weak acid and its salt or a weak base and its salt. When adjusting this buffer solution, the buffer solution can be obtained by neutralizing a part of the weak acid or weak base with a base or an acid, but it is difficult to adjust the pH delicately. It has been known that a weak base and its salt should be used. It has been known that the use of amino acids and salts thereof also has a buffering effect in a buffer solution containing amino acids,
In these buffers, the low release index (pKa) of the carboxyl group in the amino acid was 4 or less, and the pKa of the amino group was 8 or more. . However, the skin pH is generally 5.0-
It is said that it is about 6.5, and the cosmetics using the above-mentioned buffer solution have a drawback that they put a heavy burden on the skin. Further, it is known to use an acidic amino acid and a basic amino acid to obtain a buffer solution having a pH of about 5.0 to 7.0, but delicate pH adjustment is extremely difficult and not always satisfactory. .

[Problems to be Solved by the Invention] The inventors of the present invention have conducted extensive studies as to whether an amino acid can provide a buffer solution that can be easily adjusted even at around pH 5.0 to 7.0. Amino acids,
It has been found that this object can be achieved by mixing with an amino acid salt, and the present invention has been completed based on this finding.

[Means for Solving Problems] That is, the present invention is a cosmetic characterized in that an acidic amino acid, a basic amino acid, and an amino acid salt are blended.

 The configuration of the present invention will be described in detail below.

The acidic amino acid used in the present invention is a compound having more carboxyl groups than amino groups in the molecule, and examples thereof include aspartic acid and glutaric acid.

The basic amino acid used in the present invention is a compound having more amino groups than carboxyl groups in the molecule, and examples thereof include ornithine, tryptophan, lysine, arginine and histidine. Among these, arginine, lysine and histidine are preferable.

The amount of the acidic or basic amino acid compounded is 0.001 to 5% by weight, preferably 0.01 to 1% by weight, based on the total amount of the cosmetic. If less than 0.001% by weight, no buffering effect can be expected, and
When it exceeds the weight%, the effect does not increase so much and it is uneconomical.

Amino acid salt used in the present invention is a carboxyl group in an amino acid, or an amino group formed a salt, for example, sodium aspartate, potassium aspartate, magnesium aspartate, calcium aspartate, sodium glutamate, potassium glutamate, Magnesium glutamate, calcium glutamate, glutamate hydrochloride, cysteine hydrochloride, histidine hydrochloride, histidine acetate, histidine phosphate, lysine hydrochloride, lysine acetate, ornithine hydrochloride, ornithine acetate, tryptophan hydrochloride, arginine-glutamate. , Ornithine-glutamate, lysine-glutamate, lysine-aspartate, ornithine-
Examples include aspartate. Among these, sodium glutamate and sodium aspartate are preferable.

The amount of the amino acid salt used in the present invention is 1/10 to 50 times, preferably 1/2 to 10 times the amount of amino acid. If it is less than 1/10, the effect of facilitating pH adjustment is not sufficient, and if it exceeds 50, the effect does not increase so much.
It is uneconomical.

The cosmetic of the present invention may be any base such as a solubilizing system, an emulsifying system, a powder dispersion system, a water-oil type two-layered cosmetic composition, and a water-oil-powder type three-layered cosmetic composition. Basic cosmetics such as water, milky lotion, cream and pack, makeup cosmetics such as emulsified lipstick and foundation, hair cosmetics such as shampoo, conditioner and hair tonic. It is especially effective for those included in. The concentration of the amino acid aqueous solution is arbitrary, and there is no problem even if the amino acid aqueous solution is emulsified with the oil phase as described above.

The cosmetics of the present invention include, in a quantitative and qualitative range that does not impair the effects of the present invention, if necessary, animal or vegetable mineral oil or ester oil, triglyceride or higher fatty acid, higher alcohol, straight chain, branched, Oily components such as cyclic silicones, lower alcohols such as ethanol, natural extracts such as lecithin and carrot extracts, polyhydric alcohols and sugars, sugar alcohols, other sugar derivatives, moisturizers such as pyrrolidonecarboxylic acid, high water solubility Compounded with thickeners such as molecular compounds and clay minerals, antiseptic / antifungal agents, surfactants, antioxidants, sequestering agents, ultraviolet absorbers, inorganic or organic powders, pigments, medicinal ingredients, dyes, fragrances, etc. it can.

[Effects of the Invention] The cosmetics according to the present invention are easily adjusted to pH 5.0 to pH 7.0.
It has an excellent effect that it can adjust.

[Examples] Next, in order to further understand the present invention, test examples and examples will be described in more detail. The present invention is not limited to these.

 The numerical values are% by weight.

Test Examples 1 and 2 A solution having the following formulation (Table 1) was prepared and pH change was measured. The results are shown in Fig. 1.

As can be seen from FIG. 1, in the system in which aspartic acid was added to the arginine aqueous solution of Test Example 1, the pH dropped from around pH 7.0 to 5.0 or less due to the addition of a small amount of aspartic acid, so that it was delicate between 5.0 and 7.0. pH adjustment is very difficult.
On the other hand, in the aqueous solution of arginine and glutamic acid of Test Example 2, a gentle curve was drawn from around pH 7.0
Is decreasing, so even if it is between 5.0 and 7.0, a delicate pH
It is understood that adjustment of can be easily performed.

Test Examples 3 and 4 A solution having the following formulation (Table 2) was prepared, and a pH change was measured when a 0.001N hydrochloric acid aqueous solution or a 0.001N sodium hydroxide aqueous solution was added. The results are shown in Figure 2.

As can be seen from FIG. 2, the pH of the sodium chloride aqueous solution of Test Example 3 changes significantly when hydrochloric acid or sodium hydroxide aqueous solution is added, while the pH of the arginine-aspartic acid-sodium glutamate aqueous solution of Test Example 4 changes. Alternatively, it can be seen that the pH hardly changes with the addition of the sodium hydroxide aqueous solution, and the pH buffering ability is high.

Examples 1 and 2 A lotion was produced by a conventional method according to the following formulation. Table-
In No. 3, the pH was measured at room temperature immediately after production and after being left at room temperature or 50 ° C. for 1 month.

It can be seen from Table 3 that the cosmetic of the present invention can be easily adjusted even at a pH of 5.0 to 7.0 and has excellent stability.

Example 3 Emulsion Polyoxyethylene (20 mol addition) oleyl alcohol ether 2.0 Cetanol 0.2 Vaseline 3.0 Lanolin alcohol 2.0 Liquid paraffin 8.0 Squalane 3.0 2-Ethylhexyl-P-dimethylaminobenzoate
2.0 Glutamic acid 0.01 Histidine 0.05 Sodium aspartate 0.1 Oleic acid monoglyceride 1.0 Propylene glycol 5.0 Fragrance Suitable amount Preservative Suitable amount Distilled water Residual pH 6.4 Example 4 Nutrition cream Stearic acid 2.0 Stearic alcohol 2.0 Reduced lanolin 2.0 Squalane 5.0 Octyldodecanol 6.0 Polyoxyethylene ( 25 mol addition) Cetyl ether 3.0 Lipophilic type glyceryl monostearate 2.0 Perfume Suitable amount Preservative Suitable amount Propylene glycol 5.0 Aspartic acid 0.12 Sodium glutamate 1.0 Lysine 0.1 Glycine 1.0 Distilled water Residual pH 5.52 Example 5 Foundation Cetanol 3.5 Deodorant lanolin 4.0 Jojoba oil 5.0 Vaseline 2.0 Squalane 6.0 Stearic acid monoglycerin ester 2.5 Polyoxyethylene (60 mol addition) Hydrogenated castor oil 1.5 Polyoxyethylene (25 mol Pressure) even cetyl ether 1.0 Propylparaben 0.3 Perfume 0.2 Glycerin 3.0 Propylene glycol 8.0 Formulation powder 12.0 Urea 3.0 Arginine hydrochloride 1.0 lysine 0.2 aspartic acid 0.1 serine 0.1 Distilled water balance pH 6.4 Example 3-5, the pH is 5.0 to 7.0 The pH was easy to adjust and the cosmetic was excellent in stability.

[Brief description of drawings]

FIG. 1 is a diagram showing a pH change when arginine or arginine-sodium glutamate aqueous solution was mixed with aspartic acid and the amount thereof was changed. FIG. 2 is a diagram showing pH changes when 0.001N hydrochloric acid or sodium hydroxide aqueous solution was added to sodium chloride or arginine-aspartic acid-sodium glutamate aqueous solution.

Claims (1)

[Claims] 1. An acidic amino acid, a basic amino acid, and an amino acid salt are contained, and the content of the amino acid salt is 1/10 to 50 times the total amount of the acidic amino acid and the basic amino acid. Characteristic cosmetics.