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Reiß et al., 2012 - Google Patents
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Reiß et al., 2012 - Google Patents

Global analysis of the Staphylococcus aureus response to mupirocin

Reiß et al., 2012

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Document ID
17519089545109621735
Author
Reiß S
Pané-Farré J
Fuchs S
François P
Liebeke M
Schrenzel J
Lindequist U
Lalk M
Wolz C
Hecker M
Engelmann S
Publication year
Publication venue
Antimicrobial agents and chemotherapy

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In the present study, we analyzed the response of S. aureus to mupirocin, the drug of choice for nasal decolonization. Mupirocin selectively inhibits the bacterial isoleucyl-tRNA synthetase (IleRS), leading to the accumulation of uncharged isoleucyl-tRNA and eventually …
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving viable micro-organisms
    • C12Q1/18—Testing for antimicrobial activity of a material
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