transcription factor AP-1とは 意味・読み方・使い方

Disclosed is a method for regulating the transcription of one or more genes in vascular or cardiac cells, wherein the method comprises a step of bringing the above cells into contact with a composition comprising one or more double-stranded nucleic acids which can sequence-specifically bind to transcription factor AP-1 and/or C/EBP or related transcription factors.例文帳に追加

血管または心臓細胞における１個以上の遺伝子の転写を調節する方法であって、前記細胞を、転写因子AP-1および／またはC/EBPまたは関連転写 因子に配列特異的に結合できる１個以上の二本鎖核酸を含んでなる組成物と接触させる段階を含んでなる、方法。 - 特許庁

This invention relates to the medicament for prophylactic/therapeutic/ameliorating agent for proliferative nephropathy, comprising a decoy type nucleic acid medicine which inhibits coupling of a transcription factor to a coupling point, and is selected from decoy of NF-κB, decoy of STAT-6, decoy of AP-1, decoy of Ets and decoy of E2F.例文帳に追加

転写調節因子の結合部位への結合を阻害するおとり型核酸医薬（デコイ）であるNF-κBのデコイ、STAT-6のデコイ、AP-1のデコイ、Etsのデコイ及びE2Fのデコイから選ばれるものを有効成分とする、増殖性腎疾患の予防・治療・改善剤。 - 特許庁

To obtain a gene expression inhibitor through motif of transcription factor AP-1 effective for alleviation and amelioration of symptom of disease accompanied by inflammation and fever.例文帳に追加

炎症ならびに発熱を伴う疾病の症状の緩和と改善、ならびに癌増殖の抑制に有効な転写因子ＡＰ−１のモチーフを介した遺伝子発現の抑制剤を提供する。 - 特許庁