「Topoisomerase」の共起表現一覧(1語右で並び替え)
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to be related to the inhibition of type II | topoisomerase activity since teniposide does not interca |
The | topoisomerase also does not use ATP during uncoiling of |
tein kinases, inhibition of eukaryotic DNA | topoisomerase, and intercalative binding to DNA. |
(ATA) are autoantibodies directed against | topoisomerase and found in several diseases, most import |
Type II | topoisomerase cuts both strands of one DNA double helix, |
ase, often abbreviated to Cre, is a Type I | topoisomerase from P1 bacteriophage that catalyzes site- |
Topoisomerase I is an enzyme that relaxes the strain on | |
The inhibition of | topoisomerase I by the active metabolite SN-38 eventuall |
aims that there is an increased density of | Topoisomerase I sites in the collagen genes, and that th |
Topoisomerase I is the antigen recognized by Anti Scl-70 | |
They are also referred to as anti-DNA | topoisomerase I antibody (anti-topo I). |
Topoisomerase I is an enzyme that mediates reversible si | |
Anti Scl-70 ( | topoisomerase I) |
ecan binds to and inhibits the activity of | topoisomerase I, stabilizing the cleavable complex of to |
ed by hydrolysis to SN-38, an inhibitor of | topoisomerase I. |
Active site of | Topoisomerase IB. |
ay be directly associated with the role of | topoisomerase II in disjoining sister chromatids prior t |
Inhibition of Aurora B due to loss of | topoisomerase II seems to depend on BubR1 activity (see |
is a potent inhibitor of ribonuclease and | topoisomerase II by preventing the binding of the nuclei |
natural, or induced by other inhibitors of | topoisomerase II that act as inhibitors of topoisomerase |
HU-331 inhibits DNA | topoisomerase II even at nanomolar concentrations, but h |
Also, cells deficient in | topoisomerase II show significantly reduced Aurora B kin |
Recently, | topoisomerase II has been implicated in the regulation o |
U-331 seems to be a catalytic inhibitor of | topoisomerase II, probably by enzymatic ligation to the |
It also triggers DNA cleavage by | topoisomerase II, resulting in mechanisms that lead to c |
In | topoisomerase II-depleted cells, Aurora B and INCENP do |
are a reflection of the stabilization of a | topoisomerase II-DNA intermediate. |
hey act as anti-cancer drugs by inhibiting | topoisomerase II. |
The interaction of RecQ helicase with | topoisomerase III at the N-terminal region is involved i |
ses requires the specific interaction with | topoisomerase III (Top 3). |
Examples of type IIB | topoisomerase include topo VI. |
See also | topoisomerase inhibitor |
Amsacrine also expresses | topoisomerase inhibitor activity, specifically inhibitin |
ther polyphenols, was found to be a strong | topoisomerase inhibitor, sharing similarities to chemoth |
ICRF 193 is a | topoisomerase inhibitor. |
Mitoxantrone is a type II | topoisomerase inhibitor; it disrupts DNA synthesis and D |
Some chemotherapy drugs called | topoisomerase inhibitors work by interfering with mammal |
ites, but common for alkylating agents and | topoisomerase inhibitors. |
Together, gyrase and | topoisomerase IV remove the positive supercoils that acc |
Like gyrase, | topoisomerase IV is able to pass one double-strand of DN |
Topoisomerase IV has two functions in the cell. | |
Topoisomerase IV is one of two type-II topoisomerases in | |
Topoisomerase IV is also a target of antibiotics, such a | |
Topoisomerase IV's second function in the cell is to rel | |
lled anti-topoisomerase I after the type I | topoisomerase target) is a type of anti-nuclear autoanti |
First inhibiting | topoisomerase, which stabilize the topoisomerase-DNA com |
The antibiotic inhibits the enzyme | topoisomerase, which bacteria need to replicate. |
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