NO330772B1 - Oksa- og tiadiazoler og deres fremstilling, deres anvendelse for fremstilling av metalloproteinasehemmer-medikamenter, og sammensetninger inneholdende Oksa- og tiadiazolene - Google Patents

Oksa- og tiadiazoler og deres fremstilling, deres anvendelse for fremstilling av metalloproteinasehemmer-medikamenter, og sammensetninger inneholdende Oksa- og tiadiazolene Download PDF

Info

Publication number: NO330772B1
Authority: NO; Norway
Prior art keywords: alkyl; phenyl; compound according; heteroaryl; butyl
Prior art date: 2002-02-22

Application number

NO20043846A

Other languages

English (en)

Norwegian (no)

Other versions

NO20043846L (no

Inventor

Andrew Paul Ayscough

Stephen John Davies

Gilles Pain

Jean-Yves Gillon

Original Assignee

Vernalis Oxford Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-02-22

Filing date

2004-09-14

Publication date

2011-07-11

2004-09-14 Application filed by Vernalis Oxford Ltd filed Critical Vernalis Oxford Ltd

2004-09-14 Publication of NO20043846L publication Critical patent/NO20043846L/no

2011-07-11 Publication of NO330772B1 publication Critical patent/NO330772B1/no

Links

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- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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NO20043846A 2002-02-22 2004-09-14 Oksa- og tiadiazoler og deres fremstilling, deres anvendelse for fremstilling av metalloproteinasehemmer-medikamenter, og sammensetninger inneholdende Oksa- og tiadiazolene NO330772B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0204159.8A GB0204159D0 (en)	2002-02-22	2002-02-22	Metalloproteinase inhibitors
PCT/GB2003/000741 WO2003070711A1 (en)	2002-02-22	2003-02-20	Oxa- and thiadiazoles and their use as metalloproteinase inhibitors

Publications (2)

Publication Number	Publication Date
NO20043846L NO20043846L (no)	2004-09-14
NO330772B1 true NO330772B1 (no)	2011-07-11

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ID=9931543

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Application Number	Title	Priority Date	Filing Date
NO20043846A NO330772B1 (no)	2002-02-22	2004-09-14	Oksa- og tiadiazoler og deres fremstilling, deres anvendelse for fremstilling av metalloproteinasehemmer-medikamenter, og sammensetninger inneholdende Oksa- og tiadiazolene

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US (4)	US7358265B2 (sr)
EP (1)	EP1476438B1 (sr)
JP (1)	JP4615864B2 (sr)
KR (1)	KR101098614B1 (sr)
CN (1)	CN100351245C (sr)
AT (1)	ATE360007T1 (sr)
AU (1)	AU2003205910B2 (sr)
BR (1)	BR0307899A (sr)
CA (1)	CA2475867C (sr)
CY (1)	CY1106730T1 (sr)
DE (1)	DE60313292T2 (sr)
DK (1)	DK1476438T3 (sr)
EA (1)	EA007609B1 (sr)
ES (1)	ES2286404T3 (sr)
GB (1)	GB0204159D0 (sr)
HR (1)	HRP20040725A2 (sr)
IL (1)	IL163413A (sr)
MX (1)	MXPA04008132A (sr)
NO (1)	NO330772B1 (sr)
PL (1)	PL210773B1 (sr)
PT (1)	PT1476438E (sr)
RS (1)	RS51354B (sr)
SI (1)	SI1476438T1 (sr)
UA (1)	UA78275C2 (sr)
WO (1)	WO2003070711A1 (sr)
ZA (1)	ZA200406755B (sr)

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AU2003227952A1 (en) *	2003-05-17	2004-12-03	British Biotech Pharmaceuticals Ltd	Metalloproteinase inhibitors
US7786121B2 (en) *	2003-08-23	2010-08-31	Vernalis (Oxford) Limited	Derivatives of hydroxamic acid as metalloproteinase inhibitors
US7838522B2 (en)	2004-11-17	2010-11-23	Ares Trading S.A.	Benzothiazole formulations and use thereof
PT1828160E (pt)	2004-12-21	2012-01-05	Merck Serono Sa	Derivados cíclicos de sulfonilamino e sua utilização
RS51957B (sr)	2005-01-31	2012-02-29	Merck Serono Sa.	Derivati n-hidroksiamida i njihova upotreba
KR20080044836A (ko)	2005-07-15	2008-05-21	라보라뚜와르 세로노 에스. 에이.	자궁내막증 치료용 ｊｎｋ 억제제
BRPI0613042A2 (pt)	2005-07-15	2010-12-14	Serono Lab	inibidores de jnk para o tratamento de endometriose
EA013816B1 (ru)	2005-09-01	2010-08-30	Арес Трейдинг С.А.	Лечение неврита зрительного нерва
US8153166B2 (en) *	2006-06-08	2012-04-10	Chih-Hsiung Lin	Composition for prophylaxis or treatment of urinary system infection and method thereof
HUE038169T2 (hu)	2013-09-06	2018-09-28	Aurigene Discovery Tech Ltd	1,2,4-Oxadiazol származékok mint immunomodulátorok
BR112017019304A2 (pt) *	2015-03-10	2018-05-08	Aurigene Discovery Technologies Limited	compostos de 1,2,4-oxadiazol 3-substituído e tiadiazol como imunomoduladores
KR102894264B1 (ko)	2015-03-10	2025-12-02	오리진 온콜로지 리미티드	면역조절제로서의 1,2,4-옥사다이아졸 및 티아다이아졸 화합물
CN105384736B (zh) *	2015-10-28	2018-11-02	南昌大学	一种ⅳ型胶原酶抑制剂及合成方法
WO2019061324A1 (en)	2017-09-29	2019-04-04	Curis Inc.	CRYSTALLINE FORMS OF IMMUNOMODULATORS
EP3694841A1 (en)	2017-10-11	2020-08-19	Aurigene Discovery Technologies Limited	Crystalline forms of 3-substituted 1,2,4-oxadiazole
MY206121A (en)	2017-11-03	2024-11-29	Aurigene Discovery Tech Ltd	Dual inhibitors of tim-3 and pd-1 pathways
AU2018360389B2 (en)	2017-11-06	2024-09-19	Aurigene Oncology Limited	Conjoint therapies for immunomodulation
CN108530378B (zh) *	2018-05-29	2021-09-14	济南大学	一类含有噁二唑结构的氮原子双取代异羟肟酸类化合物、用途及其制备方法

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US5665753A (en) *	1994-03-03	1997-09-09	Smithkline Beecham Corporation	Cytokine inhibiting imidazole substituted hydroxamic acid derivatives
GB9404046D0 (en) *	1994-03-03	1994-04-20	Smithkline Beecham Corp	Novel compounds
US5703092A (en)	1995-04-18	1997-12-30	The Dupont Merck Pharmaceutical Company	Hydroxamic acid compounds as metalloprotease and TNF inhibitors
ES2212142T3 (es) *	1996-12-17	2004-07-16	Warner-Lambert Company Llc	Uso de inhibidores de metaloproteinasas de la matriz para promover la curacion de heridas.
JP2002506873A (ja) *	1998-03-18	2002-03-05	アリアド・ファーマシューティカルズ・インコーポレイテッド	複素環式シグナル伝達阻害剤、それを含む組成物
JP2001031637A (ja) *	1999-05-17	2001-02-06	Fuji Chemical Industries Ltd	新規なヒドロキサム酸誘導体
GB9930570D0 (en) *	1999-12-23	2000-02-16	Pfizer Ltd	Therapy
US6448278B2 (en)	1999-12-23	2002-09-10	Pfizer Inc.	Procollagen C-proteinase inhibitors

2002
- 2002-02-22 GB GBGB0204159.8A patent/GB0204159D0/en not_active Ceased
2003
- 2003-02-20 UA UA20040806941A patent/UA78275C2/uk unknown
- 2003-02-20 DK DK03702791T patent/DK1476438T3/da active
- 2003-02-20 RS YUP-716/04A patent/RS51354B/sr unknown
- 2003-02-20 US US10/504,317 patent/US7358265B2/en not_active Expired - Fee Related
- 2003-02-20 MX MXPA04008132A patent/MXPA04008132A/es active IP Right Grant
- 2003-02-20 KR KR1020047012821A patent/KR101098614B1/ko not_active Expired - Fee Related
- 2003-02-20 DE DE60313292T patent/DE60313292T2/de not_active Expired - Lifetime
- 2003-02-20 AU AU2003205910A patent/AU2003205910B2/en not_active Ceased
- 2003-02-20 JP JP2003569618A patent/JP4615864B2/ja not_active Expired - Fee Related
- 2003-02-20 CA CA2475867A patent/CA2475867C/en not_active Expired - Fee Related
- 2003-02-20 PL PL372268A patent/PL210773B1/pl unknown
- 2003-02-20 ES ES03702791T patent/ES2286404T3/es not_active Expired - Lifetime
- 2003-02-20 EP EP03702791A patent/EP1476438B1/en not_active Expired - Lifetime
- 2003-02-20 BR BR0307899-0A patent/BR0307899A/pt not_active IP Right Cessation
- 2003-02-20 AT AT03702791T patent/ATE360007T1/de active
- 2003-02-20 EA EA200401095A patent/EA007609B1/ru not_active IP Right Cessation
- 2003-02-20 SI SI200330870T patent/SI1476438T1/sl unknown
- 2003-02-20 CN CNB038089122A patent/CN100351245C/zh not_active Expired - Fee Related
- 2003-02-20 PT PT03702791T patent/PT1476438E/pt unknown
- 2003-02-20 WO PCT/GB2003/000741 patent/WO2003070711A1/en not_active Ceased
- 2003-02-20 HR HR20040725A patent/HRP20040725A2/hr not_active Application Discontinuation
2004
- 2004-08-09 IL IL163413A patent/IL163413A/en not_active IP Right Cessation
- 2004-08-25 ZA ZA200406755A patent/ZA200406755B/en unknown
- 2004-09-14 NO NO20043846A patent/NO330772B1/no not_active IP Right Cessation
2007
- 2007-07-13 CY CY20071100937T patent/CY1106730T1/el unknown
2008
- 2008-02-08 US US12/028,275 patent/US20080227833A1/en not_active Abandoned
2009
- 2009-10-14 US US12/588,372 patent/US20100035943A1/en not_active Abandoned
2010
- 2010-10-07 US US12/900,262 patent/US20110086893A1/en not_active Abandoned

Also Published As

Publication number	Publication date
KR101098614B1 (ko)	2011-12-23
EA200401095A1 (ru)	2005-02-24
PT1476438E (pt)	2007-07-25
PL210773B1 (pl)	2012-02-29
BR0307899A (pt)	2004-12-07
CA2475867C (en)	2011-07-05
CN1646505A (zh)	2005-07-27
DE60313292T2 (de)	2007-12-27
DE60313292D1 (de)	2007-05-31
WO2003070711A1 (en)	2003-08-28
AU2003205910B2 (en)	2008-12-04
CY1106730T1 (el)	2012-10-24
CN100351245C (zh)	2007-11-28
US20050222189A1 (en)	2005-10-06
EA007609B1 (ru)	2006-12-29
ATE360007T1 (de)	2007-05-15
US20110086893A1 (en)	2011-04-14
IL163413A (en)	2010-11-30
KR20040101232A (ko)	2004-12-02
MXPA04008132A (es)	2005-06-17
NO20043846L (no)	2004-09-14
US7358265B2 (en)	2008-04-15
SI1476438T1 (sl)	2007-10-31
DK1476438T3 (da)	2007-08-20
GB0204159D0 (en)	2002-04-10
HRP20040725A2 (en)	2005-04-30
EP1476438A1 (en)	2004-11-17
YU71604A (sh)	2006-08-17
US20080227833A1 (en)	2008-09-18
JP4615864B2 (ja)	2011-01-19
JP2005522455A (ja)	2005-07-28
UA78275C2 (en)	2007-03-15
HK1078583A1 (zh)	2006-03-17
EP1476438B1 (en)	2007-04-18
ZA200406755B (en)	2006-07-26
ES2286404T3 (es)	2007-12-01
PL372268A1 (en)	2005-07-11
RS51354B (sr)	2011-02-28
CA2475867A1 (en)	2003-08-28
AU2003205910A1 (en)	2003-09-09
US20100035943A1 (en)	2010-02-11

Legal Events

Date	Code	Title	Description
2013-09-30	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
NO330772B1 (no)	2011-07-11	Oksa- og tiadiazoler og deres fremstilling, deres anvendelse for fremstilling av metalloproteinasehemmer-medikamenter, og sammensetninger inneholdende Oksa- og tiadiazolene
US8889674B2 (en)	2014-11-18	Piperidine and pyrrolidine derivatives having NPY Y5 receptor antagonism
EP2046764A1 (en)	2009-04-15	Substituted isoxalines, pharmaceutical compositions containing same, methods of preparing same, and uses of same
TW201016690A (en)	2010-05-01	Compounds which selectively modulate the CB2 receptor
EA009051B1 (ru)	2007-10-26	О-замещенные гидроксиарильные производные
NZ338082A (en)	2000-06-23	Metalloproteinase and Tumor Necrosis Factor-alpha convertase inhibitors, pharmaceutical compositions and their use in treating disease mediated by metalloproteinase activity.
TWI395743B (zh)	2013-05-11	具有ｐｐａｒ激動劑活性之衍生物
CA2721576A1 (en)	2009-10-29	Compound having npy y5 receptor antagonist activity
JP5760006B2 (ja)	2015-08-05	Ｄｐｐ−１の阻害剤として有用な置換ベンゾチアゾール誘導体及び置換ベンゾオキサゾール誘導体
WO2001010835A1 (en)	2001-02-15	Antibacterial agents
AU2021342568B2 (en)	2025-04-03	Nlrx1 ligands
NO164352B (no)	1990-06-18	Analogifremgangsmaate for fremstilling av farmasoeytisk aktive, antivirale, substituerte isoksazolderivater.
WO2004101537A1 (en)	2004-11-25	Metalloproteinase inhibitors
KR101954420B1 (ko)	2019-06-13	5-카바모일 아다만탄-2-일 아마이드 유도체, 이의 약학적으로 허용 가능한 염 및 이의 제조 방법
US20070208021A1 (en)	2007-09-06	Phenoxyacetic Acid Derivatives and Drug Comprising The Same
KR100402561B1 (ko)	2003-10-17	하이드라진 유도체
US20040209822A1 (en)	2004-10-21	Novel compounds
CN1938287A (zh)	2007-03-28	苯氧基乙酸衍生物和包含其的药物
GB2315750A (en)	1998-02-11	Metalloproteinase inhibitors