Deprecated: The each() function is deprecated. This message will be suppressed on further calls in /home/zhenxiangba/zhenxiangba.com/public_html/phproxy-improved-master/index.php on line 456
EP3144618B2 - Lyophilisateur - Google Patents
[go: Go Back, main page]

EP3144618B2 - Lyophilisateur - Google Patents

Lyophilisateur Download PDF

Info

Publication number
EP3144618B2
EP3144618B2 EP16191639.0A EP16191639A EP3144618B2 EP 3144618 B2 EP3144618 B2 EP 3144618B2 EP 16191639 A EP16191639 A EP 16191639A EP 3144618 B2 EP3144618 B2 EP 3144618B2
Authority
EP
European Patent Office
Prior art keywords
freeze
drying
drying system
guides
carriage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP16191639.0A
Other languages
German (de)
English (en)
Other versions
EP3144618A1 (fr
EP3144618B1 (fr
Inventor
Martin Christ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MARTIN CHRIST GEFRIERTROCKNUNGSANLAGEN GmbH
Original Assignee
MARTIN CHRIST GEFRIERTROCKNUNGSANLAGEN GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47178567&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP3144618(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by MARTIN CHRIST GEFRIERTROCKNUNGSANLAGEN GmbH filed Critical MARTIN CHRIST GEFRIERTROCKNUNGSANLAGEN GmbH
Publication of EP3144618A1 publication Critical patent/EP3144618A1/fr
Publication of EP3144618B1 publication Critical patent/EP3144618B1/fr
Application granted granted Critical
Publication of EP3144618B2 publication Critical patent/EP3144618B2/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B25/00—Details of general application not covered by group F26B21/00 or F26B23/00
    • F26B25/001—Handling, e.g. loading or unloading arrangements
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing

Definitions

  • the invention relates to a freeze dryer with a freeze dryer carriage.
  • Freeze-drying systems are designed for discontinuous operation in many cases and mainly consist of a drying chamber and a condenser chamber connected to it via a closable opening, the material to be dried being held in a large number of drying vessels, vials, ampoules or trays that are to be carried out drying on a footprint within a drying chamber.
  • a large number of such shelves are arranged in a frame vertically displaceable one above the other.
  • a freeze drying system in which the drying vessels stand up on a conveyor belt in a position in front of the entrance opening of the housing of this system are transported in order to be subsequently introduced into the housing in rows in a direction perpendicular to the feed direction of the conveyor belt for the purpose of carrying out the drying process.
  • a device for moving the drying vessels, consists of two slides, which are supported on both sides of a loading surface in a loading position and are connected to one another by a sliding bar, the sliding bar being set up both for pushing in the drying vessels and for pushing out the drying vessels after drying is.
  • the sliding bar can be pivoted between a lowered active position, that is to say it is intended to rest against the drying vessels, and an inactive raised position, that is to say, to drive over the drying vessels standing on the standing surface, about an axis extending parallel to the standing surface.
  • the sliding bar is first pivoted into the inactive position, retracted into the housing above the drying vessels and finally pivoted back into its active position on the back of the group of drying vessels opposite the entrance opening, in which it is available for being pushed out . Maintaining aseptic conditions is problematic due to running over the drying vessels, in particular due to unavoidable abrasion.
  • a slide is provided in a row perpendicular to the direction of advance of the conveyor belt for sliding in the housing of the drying vessels initially standing on a conveyor belt, a slide bar also being arranged which extends parallel to the slide and by means of two Chain hoists guided laterally along the shelf in the loading or unloading position can be moved into and out of the housing.
  • the sliding bar can in turn be pivoted about a horizontal axis between a lowered active position, that is to say that it rests against the group of standing drying vessels, and a raised inactive position that is intended for driving over the group.
  • a further freeze-drying system in which a slide which can be inserted into the housing through its inlet opening is provided for the series insertion of drying vessels into the system, the group of drying vessels inserted into the housing being inserted during the insertion abuts a bar that can also be moved into the housing and stabilizes the standing position of the drying vessels.
  • the bar is supported at both ends on a carriage and can be pivoted at this between a lower active position in contact with the drying vessels and an upper inactive position intended for driving over the group of drying vessels.
  • the slide and the bar can be completely moved out of the housing.
  • the bar acts as an ejector when the drying vessels are pushed out, whereas the slide acts as a stabilizer
  • WO 2011/015453 A1 discloses a ventilated and temperature-controlled transport vehicle with which drying vessels can be transported between individual stations of a freeze-drying system.
  • the transport vehicle has a substructure which can be moved via a battery-powered drive and a cabinet-like storage device in which the drying vessels can be arranged during transport.
  • To transfer the drying vessels to a drying chamber of a freeze dryer the transport vehicle is moved in front of the freeze dryer and the drying vessels are pushed into the drying chamber of the freeze dryer via a telescopic loading device of the transport vehicle.
  • Fig. 1 denotes a freeze-drying system, which consists, inter alia, of a drying chamber 2 arranged in a housing 3 and a structural unit 6 carrying a loading and unloading device and slidably arranged on rails 4 in the direction of the arrows 5.
  • the assembly 6 together with rails and the housing 3 are arranged on a common base plate 7 and the assembly 6 - aside from maintenance work - is generally firmly docked to the housing.
  • Further rails 11 extend on the top 10 of the structural unit, namely parallel to the rails 4 or the arrows 5, in the direction of an opening 13 of the housing 3 provided with a closable door 12.
  • a drive is provided for closing and opening the door 12.
  • a guide unit 14 is slidably supported on the rails 11 in the direction of the arrows 5 and carries two guides 16 on the top side which are parallel to one another and accommodate a carriage 15 which will be described in more detail below.
  • On the rails 11 is also slidably supported in the direction of arrows 5 is a loading bridge 17 which also carries guides 18 on the upper side, the function of which will be explained below.
  • the carriage 15 can be moved along the guides 16, 18, which are of identical design to one another.
  • the guides 16, 18 are dimensioned and arranged in connection with the displaceability of the guide unit 14 and the loading bridge 17 in the direction of the arrows 5 with the proviso that the carriage 15 is in a front limit position or loading position on the side of the conveyor belt facing away from the housing 3 8 is displaceable.
  • the drying chamber 2 is equipped in a known manner with an arrangement of mutually parallel, horizontally extending shelves 19, which are held vertically movable in a frame 20 and each serve to set up drying vessels containing a substance to be dried, and which after the drying process has been completed from the Drying chamber 2 are to be led out.
  • the drying chamber 2 there is a height position, which corresponds to the loading and unloading position of a shelf 19, hereinafter referred to as the shifting plane, wherein each of the shelves can be moved into this shifting plane.
  • This is the height position within the drying chamber in which, when the door 12 is open, drying vessels can be inserted or executed in the drying chamber 2 in a manner to be explained below, by means of the slide 15.
  • the top view according to Fig. 2 as well as the representation according to Fig. 3 show a positioning plate 19 which is in the loading position.
  • this plane of displacement there are further guides 21, 22, the nature of which corresponds to that of the guides 16, 18.
  • the guides 21, 22 are arranged displaceably in their longitudinal direction within the housing 3, whereas their height position is fixed.
  • Carriage 15, shown laterally held in the guides 16, is characterized on its front side 23 and on the rear side 24 opposite it in the direction of the arrows 5 by mutually identical guide surfaces which are intended for contact with the drying vessels to be pushed in or out.
  • the support of the slide 15 in the guides 16 is carried out by running wheels 25, which are connected to one another by a toothed belt 26, the toothed belt 26 additionally having an external toothing, which with a corresponding profiling of the guides 16 and other guides 18, 21, 22 in Intervention stands. All drive and control components of the carriage 15 are accommodated in a flat housing 27, the height of which corresponds approximately to that of the guides 16 and is thus less than that of a drying vessel.
  • a battery-powered electric drive can be used within the carriage 15, a non-contact, for. B. inductively effective charging station 28 is set up. ( Fig. 1 )
  • the width of the area available for standing up should correspond to an integral multiple of the diameter or a comparable dimension of a drying vessel.
  • the individual rows of drying vessels pushed onto the loading bridge 17 should be laterally offset with respect to one another by half a diameter in order to to achieve optimal packing density. In this way, a mutual support effect of the drying vessels with one another can be represented.
  • the loading bridge 17 equipped with side guides 29 and the footprint 19 with side guides 30, 31.
  • These each form lateral guide edges for the drying vessels and are arranged transversely to the direction of insertion, thus displaceably in the direction of arrows 32, so that adjustment to different dimensions of the drying vessels is possible.
  • Drives are provided for the lateral adjustment of the side guides 29 to 31.
  • Each of the shelves 19 is provided in the corner region of its rectangular base with protruding likewise rectangular lugs 33 which extend in the plane of the respective shelf 19, each of which is provided with an approximately semicircular recess 34 which is open toward the peripheral outside.
  • these recesses 34 serve to guide the shelves 19 vertically. In this way, an exact vertical guidance of the shelves 19 is shown.
  • the longitudinal displaceability of the guides 21, 22 given in this way is set up with the proviso that in a Fig. 6 First limit position shown, the mutually opposite end faces of two successive guides 21, 22 are spaced apart, whereas in a second limit position these end faces are directly adjacent to one another, thus forming a continuous, approximately continuous guide path for the carriage 15.
  • the first limit position is characterized in that the shelves 19 are freely movable vertically.
  • the second limit position is characterized in that a footprint 19 is in the loading and unloading position or shifting plane mentioned at the outset and is positively secured in this.
  • the in Fig. 7 left-hand end plates 39, 40 ( Fig. 7 , 8th ) the carriage 36, 37 is equipped with horizontally extending bolts 41 which fulfill a supporting function.
  • Fig. 8 shows the carriage 36 in the first limit position, wherein it can be seen that a vertical movement of the shelves 19 is not hindered by the bolt 41.
  • Fig. 10 shows the carriage in the second limit position, wherein it can be seen that a section of an extension 33 facing the bolt 41 now lies on the bolt 41, thus preventing a further downward movement of the adjusting plate 9.
  • Fig. 11 the door 12 of the housing 3 has been moved vertically into its open position, whereby how Fig. 12 shows, the guides 21, 22 are shifted into their second limit position, thus abutting one another on the end face and forming a continuous guide for the slide 15 within the drying chamber 2.
  • the guide unit 14 is also displaced together with the loading bridge 17 in the direction of the arrows 5 with the proviso that the loading bridge 17 and thus its guides 18 abut the guides 21 inside the drying chamber 2 on the end face, so that the loading bridge 17 partially into the drying chamber 2 has been moved into it.
  • a first row of drying vessels 42 moves via the conveyor belt 8 into a position in front of the carriage 15, which is thus located on the side of the conveyor belt 8 facing away from the housing 3.
  • drying vessels 42 By subsequently providing rows of drying vessels 42 cyclically via the conveyor belt 8, possibly with the guide unit 14 being moved back on the rails 11 in the direction away from the housing 3, these rows are formed by means of the Slide slides 15 one after the other over the loading bridge 17 onto the topmost shelf 19 of the plurality of shelves 19 in the drying chamber 2, which is in the loading position, until the drying chamber 2 has reached its full capacity for drying vessels 42.
  • the drying vessels are placed in a manner known per se with the proviso that successive rows are positioned offset in the direction of insertion perpendicular to this direction, namely by cyclical transverse displacement by means of an offset 43, so that an optimal packing density is achieved.
  • This state of the complete loading of the shelf 19 in the loading position is shown in FIG Fig. 14 shown.
  • Fig. 15 the carriage 15 is then moved in the rearward direction, that is to say from that on the last-mentioned footprint 19, this process then being repeated after transferring the next footprint 19 into the loading position until all of the shelves 19 are loaded up to the initially lowest and after Withdrawal of the loading bridge 17 from the drying chamber 2 and closing the door 12 the method of freeze-drying can be carried out in a manner known per se.
  • an empty shelf level is set up in the loading position, which corresponds to the unloading position, namely below the loaded shelves 9, if necessary after their vertical displacement, after opening the door 12 and moving the guide unit 14 and inserting the loading bridge 17 into the drying chamber 2 the guides 18, 21, 22 are pushed against one another in the longitudinal direction thereof, again establishing a continuous displacement possibility for the slide 15.
  • This is then moved into this empty insertion level, thereby passing underneath the loaded shelves 19, to its rear limit position opposite the door 12 within the drying chamber 2.
  • the loaded shelf 19 located immediately above the initially empty insertion level is moved into the Lowered level of displacement and secured in this position in a form-fitting manner by moving the guides 16, 18 in their second limit position.
  • the carriage 15 is located now on the back of the group of drying vessels 42, which is opposite the door 12. This position of the slide is in Fig. 16 shown.
  • the carriage 15 is now driven for the purpose of pushing out the drying vessels via the loading bridge 17 onto the conveyor belt 8, on which the drying vessels 42 treated by freeze-drying are discharged in the direction of the arrow 9.
  • the carriage 15 is then moved along an now empty shelf 19 again into the drying chamber 2 to its rearward end position, passing under the next shelf 19 to be unloaded.
  • the latter footprint is then lowered into the unloading position and secured in a form-fitting manner, whereupon the unloading process is continued with the cooperation of the carriage 15 and the conveyor belt 8.
  • the shelves 19 are thus unloaded one after the other by means of only one carriage, the carriage 15 always passing under the loaded shelves 19, so that aseptic conditions are maintained.
  • the freeze-drying system has a drying chamber 2 arranged in a housing 3 and an arrangement in the drying chamber 2 of shelves 19 which are arranged displaceably in the height position in a frame 20 and are intended for setting up drying vessels 42 containing a drying substance.
  • the housing 3 has at least one opening 13 which can be closed by a door 12.
  • the height position of the opening 13 defines at least one horizontal displacement plane in which the guides 16, 18, 21, 22 extend, assuming a fixed height.
  • the arrangement of the setting plates 19 can be displaced vertically within the drying chamber 2 such that the carriage 15 is inserted in the shifting plane by moving under loaded loading areas 19, thus avoiding direct or indirect driving over loaded loading areas 19 into a rear limit position in the drying chamber 2 and after lowering the next higher loaded shelf 19 into the shifting plane a possibility of pushing out of the drying vessels 42 is shown via the opening 13 out of the drying chamber 2 by means of the front side 23 of the carriage 15 forming a second movable leading edge.
  • the displacement plane in the drying chamber 2 and on the loading and unloading device is preferably defined by the fixed height of the guides 16, 18, 21, 22.
  • the loading and unloading device may comprise a conveyor belt 8, the conveying direction of which extends transversely to a direction in which the drying vessels 42 are pushed in or out of the drying vessels 42 from the drying chamber 2.
  • the loading and unloading device preferably has a loading bridge 17 carrying the guides 18, which can be inserted into the drying chamber 2 for the purpose of connection to the guides 21.
  • a front limit position of the carriage 15 is arranged on the loading and unloading device.
  • the front limit position is on a side of the conveyor belt 8 opposite the drying chamber 2.
  • a power supply and / or control of the drive is set up via the guides 16, 18, 21, 22.
  • side guides 29, 30, 31 are provided for the drying vessels 42 which are to be pushed into or out of the drying chamber 2 and which are arranged such that they can be displaced perpendicularly to the direction of pushing in or pushing out, the guides 16, 18, 21 , 22 are fixedly arranged in this direction.
  • the loading and unloading device prefferably supported on a structural unit 6, which is arranged to be movable in a direction away from the drying chamber 2 or in the direction of the latter.
  • the drying vessels 42 containing the substance to be dried are pushed one after the other onto the shelf 19 to be loaded in rows by means of the rear side 24 of the carriage 15 until the loading process of this shelf 19 is complete.
  • the loading process of the following shelves 19 is continued until the loading of the drying chamber 2 is completed.
  • the carriage 15 in the displacement plane is moved into the drying chamber 2 into its rear limit position by driving under loaded shelves 19.
  • the parking space 19 under which it is driven is lowered into the displacement plane.
  • the drying vessels 42 standing on the shelf 19 located in the displacement plane are pushed out via the opening 13 by means of the front 23 of the slide 15.
  • the process of inserting the carriage 15 in the shifting plane into the drying chamber 2 by moving under a loaded loading area 19 located above the shifting level into the rear limit position, lowering the loaded standing area 19 into the shifting plane and pushing out the drying vessels 42 via the Opening 13 is then repeated cyclically until the unloading process of drying chamber 2 is completed.
  • the carriage is moved into the drying chamber at the beginning and during the successive unloading of the shelves in a shifting plane, which can be an empty shelf, the pressure plate of the arrangement of shelves or the space below the pressure plate.
  • a shifting plane which can be an empty shelf, the pressure plate of the arrangement of shelves or the space below the pressure plate.
  • the floor space to be unloaded is always passed under and then lowered into the shifting plane, whereupon the unloading process follows.
  • the guides intended for mounting the slide may be arranged in a fixed height position and define the position of the displacement plane.
  • a conveyor belt forms part of the loading and unloading device, the direction of conveyance of which extends transversely to the direction of insertion and removal.
  • a transport carriage can also be used, the size of which depends on the footprint and which, in addition to the guides mentioned, also has a parking position intended for the carriage.
  • a trolley has no conveyor belt.
  • the loading and unloading device comprises a loading bridge, the guides of which cooperate with the guides within the drying chamber when the carriage is supported.
  • the carriage preferably has a second limit position located outside the drying chamber. This position can be used as a parking position during the drying process. Starting from the drying chamber, it is set up on the other side of the conveyor belt if it is also to be used for loading. In other cases, it can also be set up on the loading bridge.
  • An electric drive is used here, which can also be a linear drive.
  • a preferably inductive charging station can be arranged in the second limit position.
  • Further configurations relate to the drive including the guides assigned to it.
  • a frictional connection with the guides is then preferably via a toothed belt mediates, which surrounds several wheels and in this way is also suitable for driving over gaps in segments of the guides.
  • the drive has a flat construction housing all components including a control, the overall height of which corresponds to that of the guides.
  • the housing of the slide is preferably designed as a hermetically sealed, in particular watertight unit, which is accessible to a CIP cleaning process (clean in place) within the drying chamber.
  • a second carriage which fulfills a counter-holding function and is otherwise of identical design, is provided, which is also included in the guides. Both carriages can have a parking position on the loading and unloading device and one of the two carriages can always be brought into a sliding position and the other into a position suitable for performing a counter-holding function in the displacement plane.
  • the exercise of a counter-holding function in drying vessels with a low level of security can be advantageous.
  • Another embodiment relates to the guides intended for receiving the carriage. These are segmented in the longitudinal direction and can be displaced relative to one another. At the same time, they can be designed as lateral leading edges for the drying vessels, so that in conjunction with an additional displaceable arrangement perpendicular to their longitudinal extension, simple adaptation to different dimensions of the drying vessels is possible, thus providing them with a safe stand-up position in the transverse direction for insertion or removal and at the same time preventing jamming and wedging, thus producing fewer rejects in the drying vessels.
  • the guides therefore do not necessarily have to be moved into a front-side contact position.
  • the carriage as has already been explained above, is also suitable to a certain extent for driving over spaces between segments of the guides.
  • vacuum-tight encapsulated gear units are provided, which are connected to drive units arranged outside the drying chamber.
  • the displacement movement of the segments mentioned can also be represented constructively in another way, for example linked to the drive of the carriage.
  • An intermediate space between two segments can also be bridged by moving intermediate elements which can be extended telescopically in these intermediate spaces.
  • special side guides can also be provided, which are arranged to be displaceable independently of the guides intended for receiving the slide.
  • a structural unit intended for supporting the loading and unloading device can be provided, which is arranged to be movable in the direction of the drying chamber and away from it, thus parallel to the direction of pushing in or pushing out.
  • This configuration can be used particularly advantageously for maintenance purposes.
  • This unit can be arranged, for example, on rails.
  • freeze drying system has been described above in connection with a drying chamber which is loaded and unloaded via only one opening.
  • the subject of the invention can also be used in such a system, which is designed for pass-through operation and is therefore provided with two mutually opposite openings, each of which is assigned a loading and unloading device.
  • the further configuration of the freeze drying system is directed to the known representation of a system of supports for the storage space located in the shifting plane. This enables the height of the sliding plane to be positioned independently in the drying chamber and is exemplified by an arrangement of bolts that are located between an active position in which a support function is fulfilled and an inactive position in which no support function is fulfilled relative to the footprint in the plane of movement are movable.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Drying Of Solid Materials (AREA)

Claims (14)

  1. Installation de lyophilisation (1) avec une chambre de séchage (2) et un chariot d'installation de lyophilisation (15) avec un dispositif d'entraînement électrique pour le déplacement du chariot aux guidages (21) qui sont disposés à l'intérieur de la chambre de séchage (2) de l'installation de lyophilisation, caractérisé en ce que le chariot comprend une batterie, le dispositif d'entraînement est alimenté par l'intermédiaire de la batterie et la batterie peut être chargée par l'intermédiaire d'une station de charge (28) .
  2. Installation de lyophilisation (1) selon la revendication 1, caractérisé en ce qu'une force du dispositif d'entraînement électrique est transmise avec des guidages (16; 18, 21, 22) par l'intermédiaire d'une courroie dentée (26) qui entoure plusieurs galets (25).
  3. Installation de lyophilisation (1) selon la revendication 2, caractérisé en ce que la courroie dentée (26) est conçu pour survoler les vides dans les segments des guidages (16; 18, 21, 22).
  4. Installation de lyophilisation (1) selon l'une des revendications précédentes, caractérisé en ce que le stockage du chariot d'installation de lyophilisation (15) a lieu dans des guidages (16) par des galets (25), qui sont reliés entre eux par l'intermédiaire d'une courroie dentée (26), la courroie dentée (26) comprenant en outre une denture externe, qui peut être mise en engrènement avec un profil correspondant des guidages (16; 18, 21, 22).
  5. Installation de lyophilisation (1) selon l'une des revendications 2 à 4, caractérisé en ce que les guidages (16; 18, 21, 22) sont conçus de façon à être segmentés dans la direction longitudinale et sont mobiles les uns par rapport aux autres.
  6. Installation de lyophilisation (1) selon l'une des revendications précédentes, caractérisé en ce qu'un boîtier (27) du chariot d'installation de lyophilisation (15) est conçu comme une unité étanche à l'eau hermétiquement fermée.
  7. Installation de lyophilisation (1) selon l'une des revendications précédentes, caractérisé en ce que la batterie peut être chargée par l'intermédiaire d'une station de charge sans contact (28).
  8. Installation de lyophilisation (1) selon l'une des revendications précédentes, caractérisé en ce que la station de charge sans contact (28) est une station de charge à induction.
  9. Installation de lyophilisation (1) selon l'une des revendications précédentes, caractérisé en ce que le chariot d'installation de lyophilisation (15) est un sous-ensemble contenant tous les composants du dispositif d'entraînement électrique et son dispositif de commande, dont la hauteur correspond au maximum à celle des guidages (16).
  10. Installation de lyophilisation (1) selon l'une des revendications précédentes, caractérisé par une liaison radio entre le dispositif d'entraînement électrique et un dispositif de commande se trouvant à l'extérieur d'une chambre de séchage (2), conçue pour la commande du dispositif d'entraînement électrique.
  11. Installation de lyophilisation (1) selon l'une des revendications précédentes, caractérisée en ce que la station de charge (28) est disposée à une position limite du dispositif d'entraînement électrique alimenté par une batterie, qui est disposée à l'extérieur d'une chambre de séchage (2) et est utilisée en tant que position de stationnement pendant le processus de séchage.
  12. Installation de lyophilisation (1) selon la revendication 11, caractérisée en ce que la position limite se trouve, à partir de la chambre de séchage (2), au-delà d'une bande convoyage (8), celle-ci étant également utilisée pour le chargement.
  13. Installation de lyophilisation (1) selon la revendication 11, caractérisée en ce que la position limite se trouve sur un pont de chargement (17).
  14. Installation de lyophilisation (1) selon l'une des revendications précédentes, caractérisée par un deuxième chariot remplissant une fonction de maintien, qui est logé dans les guidages (16, 18, 21, 22).
EP16191639.0A 2011-11-04 2012-11-03 Lyophilisateur Active EP3144618B2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102011117628.8A DE102011117628B4 (de) 2011-11-04 2011-11-04 Gefriertrockungsanlage mit einer Be- und Entladevorrichtung
EP12786840.4A EP2773913B1 (fr) 2011-11-04 2012-11-03 Installation de lyophilisation équipée d'un dispositif de chargement et déchargement
PCT/EP2012/004595 WO2013064266A1 (fr) 2011-11-04 2012-11-03 Installation de lyophilisation équipée d'un dispositif de chargement et déchargement

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
EP12786840.4A Division EP2773913B1 (fr) 2011-11-04 2012-11-03 Installation de lyophilisation équipée d'un dispositif de chargement et déchargement
EP12786840.4A Division-Into EP2773913B1 (fr) 2011-11-04 2012-11-03 Installation de lyophilisation équipée d'un dispositif de chargement et déchargement

Publications (3)

Publication Number Publication Date
EP3144618A1 EP3144618A1 (fr) 2017-03-22
EP3144618B1 EP3144618B1 (fr) 2017-06-21
EP3144618B2 true EP3144618B2 (fr) 2020-04-01

Family

ID=47178567

Family Applications (2)

Application Number Title Priority Date Filing Date
EP16191639.0A Active EP3144618B2 (fr) 2011-11-04 2012-11-03 Lyophilisateur
EP12786840.4A Active EP2773913B1 (fr) 2011-11-04 2012-11-03 Installation de lyophilisation équipée d'un dispositif de chargement et déchargement

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP12786840.4A Active EP2773913B1 (fr) 2011-11-04 2012-11-03 Installation de lyophilisation équipée d'un dispositif de chargement et déchargement

Country Status (6)

Country Link
US (2) US11236942B2 (fr)
EP (2) EP3144618B2 (fr)
CN (1) CN103857969B (fr)
DE (2) DE102011117628B4 (fr)
ES (2) ES2638237T5 (fr)
WO (1) WO2013064266A1 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL2003338C2 (en) * 2009-08-07 2011-02-08 Ima Life Srl Method and assembly for handling containers in a freeze dryer.
CN104302996B (zh) * 2012-03-14 2017-05-17 I·M·A·工业机械自动装置股份公司 用于移动容器的装置
ITMI20121275A1 (it) * 2012-07-23 2014-01-24 I M A Ind Macchine Automatic He S P A Apparato di movimentazione di piani di carico per macchine liofilizzatrici
ITMI20130841A1 (it) * 2013-05-23 2014-11-24 I M A Ind Macchine Automatic He S P A Dispositivo introduttore di flaconi
JP6173495B2 (ja) 2013-05-29 2017-08-02 ゲア・プロセス・エンジニアリング・アクティーゼルスカブ トロリに収容されたトレイ内の製品の直列滅菌凍結乾燥を実現する方法、方法を実施するためのシステム、および方法の使用
ITMI20131447A1 (it) * 2013-09-04 2015-03-05 I M A Ind Macchine Automatic He S P A Macchina liofilizzatrice comprendente almeno un organo di guida per dispositivi di carico
ITUA20161823A1 (it) * 2016-03-18 2017-09-18 I M A Industria Macch Automatiche S P A In Sigla Ima S P A Apparato per caricare e scaricare un liofilizzatore.
US11268759B2 (en) * 2017-03-24 2022-03-08 Azbil Corporation Housing device
JP7110360B2 (ja) 2017-10-09 2022-08-01 テルモ ビーシーティー バイオテクノロジーズ，エルエルシー 凍結乾燥方法
EP3473959B1 (fr) 2017-10-20 2020-02-12 Martin Christ Gefriertrocknungsanlagen GmbH Procédé de détermination basé sur la pression d'un paramètre de produit dans un congélateur, congélateur et produit logiciel
ES2787019T3 (es) 2017-12-15 2020-10-14 Martin Christ Gefriertrocknungsanlagen Gmbh Liofilizador, instalación de liofilización, procedimiento de funcionamiento un liofilizador y nuevo uso de un carro
CN113597532B (zh) * 2019-03-14 2023-02-17 泰尔茂比司特生物技术有限公司 冻干容器填充固定装置、系统及使用方法
CN110159721A (zh) * 2019-06-04 2019-08-23 深圳市时代高科技设备股份有限公司 传动机构及粉体干燥加热炉
CN110220370B (zh) * 2019-06-26 2023-11-17 东莞市德瑞精密设备有限公司 货架式锂电池烘烤设备
CN111219978B (zh) * 2020-03-18 2024-09-03 无锡先导智能装备股份有限公司 中转装置及烘干设备
CN113803984B (zh) * 2021-08-16 2023-02-17 上海奥星制药技术装备有限公司 一种原料药自动进出料装置
CN114294929B (zh) * 2022-01-14 2023-03-10 深圳市信亿德科技有限公司 一种具有升降机构的快速均匀烘烤的工业用烤箱
DE102022103429B3 (de) 2022-02-14 2023-05-04 Martin Christ Gefriertrocknungsanlagen Gmbh Be- und Entladeeinrichtung für einen Gefriertrockner, Verfahren und Gefriertrocknungsanlage
CN116812474A (zh) * 2023-07-06 2023-09-29 浙江同景冻干科技有限公司 一种冻干自动输送系统
CN117589670B (zh) * 2024-01-18 2024-04-09 江苏永成汽车零部件股份有限公司 用于汽车门饰板的喷漆表面质量检测系统
CN118776262B (zh) * 2024-09-12 2024-11-19 赣州职业技术学院 一种宠物饲料自动冻干设备
CN119845009B (zh) * 2025-03-24 2025-05-27 山西晋享印刷包装有限公司 一种纸浆模塑烘干加热装置

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4781067A (en) † 1987-04-30 1988-11-01 Sonoscan, Inc. Balanced scanning mechanism
US5014583A (en) † 1989-08-29 1991-05-14 Webb William J Push feed system for a saw
US20010045785A1 (en) † 1998-02-10 2001-11-29 Light Sciences Corporation Contactless energy transfer apparatus
US20040194655A1 (en) † 2003-04-04 2004-10-07 Insana Samuel P. Carriage assembly for positioning railroad cars
US20060016094A1 (en) † 2004-07-22 2006-01-26 Telstar, S.A. Device for loading and unloading containers
US20090025251A1 (en) † 2007-07-23 2009-01-29 Accurro Gmbh Apparatus for loading and unloading a tray of a freeze drying plant and method thereof
US20100070108A1 (en) † 2008-09-18 2010-03-18 Hubert Kluetsch Transfer means for a freeze drying plant
WO2011015453A1 (fr) † 2009-08-07 2011-02-10 Ima Life S.R.L. Procédé et ensemble de manutention de récipients dans un lyophilisateur
US20110088328A1 (en) † 2008-09-10 2011-04-21 Sommer Antriebs- Und Funktechnik Gmbh Operating mechanism for parking brake

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE9001612U1 (de) * 1989-04-07 1990-04-19 Finn-Aqua Santasalo-Sohlberg GmbH, 50354 Hürth Vorrichtung zum Beschicken und Entladen einer Gefriertrocknungseinrichtung
DE10307571A1 (de) 2003-02-22 2004-09-02 Steris Gmbh Einrichtung mit einer Stellfläche
EA008205B1 (ru) 2003-08-25 2007-04-27 Джеффри А. Спрей Расширяемые трубные изделия для использования в геологических структурах, способы расширения трубных изделий и способы их изготовления
GB0413117D0 (en) * 2004-06-11 2004-07-14 Boc Group Plc Freeze dryer
GB0413115D0 (en) 2004-06-11 2004-07-14 Boc Group Plc Freeze dryer
JP2006226633A (ja) * 2005-02-18 2006-08-31 Kyowa Shinku Gijutsu Kk 凍結乾燥機における小容器のローディング方法とローディング装置
ES2422210T3 (es) * 2006-07-18 2013-09-09 Telstar Technologies S L U Aparato para mover recipientes
FR2918653A1 (fr) * 2007-07-13 2009-01-16 Usifroid Sa Sa Dispositif de dechargement d'une armoire de traitement de produits
DE102009049142B4 (de) 2009-10-12 2013-06-27 Martin Christ Gefriertrocknungsanlagen Gmbh Be- und Entladevorrichtung für eine Gefriertrocknungsanlage

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4781067A (en) † 1987-04-30 1988-11-01 Sonoscan, Inc. Balanced scanning mechanism
US5014583A (en) † 1989-08-29 1991-05-14 Webb William J Push feed system for a saw
US20010045785A1 (en) † 1998-02-10 2001-11-29 Light Sciences Corporation Contactless energy transfer apparatus
US20040194655A1 (en) † 2003-04-04 2004-10-07 Insana Samuel P. Carriage assembly for positioning railroad cars
US20060016094A1 (en) † 2004-07-22 2006-01-26 Telstar, S.A. Device for loading and unloading containers
US20090025251A1 (en) † 2007-07-23 2009-01-29 Accurro Gmbh Apparatus for loading and unloading a tray of a freeze drying plant and method thereof
US20110088328A1 (en) † 2008-09-10 2011-04-21 Sommer Antriebs- Und Funktechnik Gmbh Operating mechanism for parking brake
US20100070108A1 (en) † 2008-09-18 2010-03-18 Hubert Kluetsch Transfer means for a freeze drying plant
WO2011015453A1 (fr) † 2009-08-07 2011-02-10 Ima Life S.R.L. Procédé et ensemble de manutention de récipients dans un lyophilisateur

Also Published As

Publication number Publication date
DE102011117628B4 (de) 2015-10-22
US11236942B2 (en) 2022-02-01
ES2638237T5 (es) 2021-01-18
EP3144618A1 (fr) 2017-03-22
EP3144618B1 (fr) 2017-06-21
CN103857969B (zh) 2016-03-09
EP2773913B1 (fr) 2017-03-01
DE202012013409U1 (de) 2016-11-09
ES2638237T3 (es) 2017-10-19
EP2773913A1 (fr) 2014-09-10
DE102011117628A1 (de) 2013-05-08
US20170059246A1 (en) 2017-03-02
CN103857969A (zh) 2014-06-11
US11236943B2 (en) 2022-02-01
US20140230265A1 (en) 2014-08-21
ES2624146T3 (es) 2017-07-13
WO2013064266A1 (fr) 2013-05-10

Similar Documents

Publication Publication Date Title
EP3144618B2 (fr) Lyophilisateur
DE3320848C2 (fr)
EP2613995B2 (fr) Installation de traitement de surface de carrosseries de véhicules
EP2488808B1 (fr) Dispositif de chargement et de déchargement pour une installation de lyophilisation
EP1321386B1 (fr) Système de stockage à carrousel
DE102010047744A1 (de) Be- und Entladevorrichtung für eine Gefriertrocknungsanlage
EP0359014A2 (fr) Dispositif d'évacuation de pièces injectées d'une machine à mouler des matières plastiques par injection
EP3499160B1 (fr) Lyophilisateur, installation de lyophilisateur, procédé de fonctionnement d'un lyophilisateur et nouvelle utilisation d'un chariot
EP0098573B1 (fr) Dispositif d'alimentation de pièces
DE102009000750B4 (de) Druckformzuführung und ein Verfahren zum Transport zumindest einer Druckform
EP2707664B1 (fr) Procédé et dispositif pour sécher des pièces
EP0246398A2 (fr) Dispositif de changement de moule pour un groupe de machine à injecter les matières plastiques
WO1995025688A1 (fr) Procede et dispositif de triage de decoupes
EP1837295B1 (fr) Dispositif doté d'aires de stockage, en particulier pour la réception de portes-pièces, tout comme système doté d'une bande convoyeuse et d'un dispositif destiné à la réception de portes-pièces
DE102005046821A1 (de) Horizontal-Umlauflagersystem
DE2409725C3 (de) Gefrieranlage
DE1286964B (de) Vorrichtung zum Verschieben stapelweise auf Paletten zu transportierender Kisten od. dgl.
EP4059850A1 (fr) Dispositif de remplissage pour un réservoir de tubes d'une machine d'emballage et procédé de remplissage d'un réservoir de tubes
EP0890880B1 (fr) Appareil pour le traitement de plaques d'impression
DE4435993C2 (de) Verwendung einer Vorrichtung zum Be- und Entladen eines Brenntischaufbaus mit Brenngut
DE2222599C3 (de) Vorrichtung zum selbsttätigen Beladen eines Hordenwagens
DE102013003840B4 (de) Verschiebeplattform
DE2551448A1 (de) Palettiervorrichtung
DE2330203A1 (de) Vorrichtung zum foerdern von lackierten gegenstaenden durch eine trocknungsanlage
DE2229108B2 (de) Einrichtung zum lagenweisen stapeln von gegenstaenden, insbesondere von ziegelsteinen

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN PUBLISHED

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

AC Divisional application: reference to earlier application

Ref document number: 2773913

Country of ref document: EP

Kind code of ref document: P

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

17P Request for examination filed

Effective date: 20170224

RBV Designated contracting states (corrected)

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

INTG Intention to grant announced

Effective date: 20170420

RIN1 Information on inventor provided before grant (corrected)

Inventor name: CHRIST, MARTIN

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

AC Divisional application: reference to earlier application

Ref document number: 2773913

Country of ref document: EP

Kind code of ref document: P

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

Free format text: LANGUAGE OF EP DOCUMENT: GERMAN

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 903342

Country of ref document: AT

Kind code of ref document: T

Effective date: 20170715

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 502012010622

Country of ref document: DE

REG Reference to a national code

Ref country code: NL

Ref legal event code: FP

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2638237

Country of ref document: ES

Kind code of ref document: T3

Effective date: 20171019

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170922

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170921

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG4D

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 6

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170921

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20171021

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

REG Reference to a national code

Ref country code: DE

Ref legal event code: R026

Ref document number: 502012010622

Country of ref document: DE

PLBI Opposition filed

Free format text: ORIGINAL CODE: 0009260

PLAX Notice of opposition and request to file observation + time limit sent

Free format text: ORIGINAL CODE: EPIDOSNOBS2

26 Opposition filed

Opponent name: MOLNIA, DAVID

Effective date: 20180320

Opponent name: I.M.A. INDUSTRIA MACCHINE AUTOMATICHE SPA

Effective date: 20180321

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20171130

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20171130

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20171103

REG Reference to a national code

Ref country code: BE

Ref legal event code: MM

Effective date: 20171130

REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

PLBB Reply of patent proprietor to notice(s) of opposition received

Free format text: ORIGINAL CODE: EPIDOSNOBS3

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20171103

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20171130

REG Reference to a national code

Ref country code: AT

Ref legal event code: MM01

Ref document number: 903342

Country of ref document: AT

Kind code of ref document: T

Effective date: 20171103

PLBP Opposition withdrawn

Free format text: ORIGINAL CODE: 0009264

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20171103

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO

Effective date: 20121103

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

PUAH Patent maintained in amended form

Free format text: ORIGINAL CODE: 0009272

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: PATENT MAINTAINED AS AMENDED

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

27A Patent maintained in amended form

Effective date: 20200401

AK Designated contracting states

Kind code of ref document: B2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: DE

Ref legal event code: R102

Ref document number: 502012010622

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

REG Reference to a national code

Ref country code: NL

Ref legal event code: FP

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20170621

REG Reference to a national code

Ref country code: ES

Ref legal event code: DC2A

Ref document number: 2638237

Country of ref document: ES

Kind code of ref document: T5

Effective date: 20210118

P01 Opt-out of the competence of the unified patent court (upc) registered

Effective date: 20230529

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: NL

Payment date: 20241120

Year of fee payment: 13

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20241121

Year of fee payment: 13

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20241120

Year of fee payment: 13

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20250819

Year of fee payment: 14

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20251128

Year of fee payment: 14

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: ES

Payment date: 20251216

Year of fee payment: 14