HRP20080423A2 - NOVEL SOLID BODY FORMS OF MESOPROGESTIN 11C-[4E-(HYDROXYIMINOMETHYL)-PHENYL]-17α-METHOXYMETYL-17C-METHOXI-ESTRA-4,9-DIEN-3-ONE - Google Patents

NOVEL SOLID BODY FORMS OF MESOPROGESTIN 11C-[4E-(HYDROXYIMINOMETHYL)-PHENYL]-17α-METHOXYMETYL-17C-METHOXI-ESTRA-4,9-DIEN-3-ONE

Info

Publication number: HRP20080423A2
Authority: HR; Croatia
Prior art keywords: mesoprogestin; hydroxyiminomethyl; estra; dien; phenyl
Prior art date: 2000-05-23

Application number

HR20080423A

Other languages

English (en)

Croatian (hr)

Inventor

Grawe Detlef

Hoesel Peter

Mueller Uwe

Winter Gabriele

Original Assignee

Schering Aktiengesellschaft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-23

Filing date

2001-05-09

Publication date

2008-10-31

2001-05-09 Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft

2008-10-31 Publication of HRP20080423A2 publication Critical patent/HRP20080423A2/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Reproductive Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

HR20080423A 2000-05-23 2001-05-09 NOVEL SOLID BODY FORMS OF MESOPROGESTIN 11C-[4E-(HYDROXYIMINOMETHYL)-PHENYL]-17α-METHOXYMETYL-17C-METHOXI-ESTRA-4,9-DIEN-3-ONE HRP20080423A2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP00110887A EP1157996A1 (de)	2000-05-23	2000-05-23	Neue Festkörperformen des Mesoprogestins 11Beta-[4E-(Hydroxyiminomethyl)-phenyl]-17Alpha-methoxymethyl-17Beta-methoxy-estra-4,9-dien-3-on
PCT/EP2001/005237 WO2001090137A2 (de)	2000-05-23	2001-05-09	NEUE FESTKÖRPERFORMEN DES MESOPROGESTINS 11β-[4E-(HYDROXYIMINOMETHYL)-PHENYL]-17α-METHOXYMETHYL-17β-METHOXY-ESTRA-4,9-DIEN-3-ON

Publications (1)

Publication Number	Publication Date
HRP20080423A2 true HRP20080423A2 (en)	2008-10-31

Family

ID=8168805

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
HR20080423A HRP20080423A2 (en)	2000-05-23	2001-05-09	NOVEL SOLID BODY FORMS OF MESOPROGESTIN 11C-[4E-(HYDROXYIMINOMETHYL)-PHENYL]-17α-METHOXYMETYL-17C-METHOXI-ESTRA-4,9-DIEN-3-ONE
HR20021032A HRP20021032B1 (hr)	2000-05-23	2001-05-09	NOVI OBLICI KRUTINA MEZOPROGESTIN 11ß-[4E-(HIDROKSIIMINOMETIL)FENIL]-17α-METOKSIMETIL-17ß-METOKSI-ESTRA-4,9-DIEN-3-ONA

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
HR20021032A HRP20021032B1 (hr)	2000-05-23	2001-05-09	NOVI OBLICI KRUTINA MEZOPROGESTIN 11ß-[4E-(HIDROKSIIMINOMETIL)FENIL]-17α-METOKSIMETIL-17ß-METOKSI-ESTRA-4,9-DIEN-3-ONA

Country Status (30)

Country	Link
US (1)	US7799770B2 (sr)
EP (3)	EP1157996A1 (sr)
JP (1)	JP2003534350A (sr)
KR (1)	KR100553292B1 (sr)
CN (1)	CN100384867C (sr)
AT (1)	ATE397617T1 (sr)
AU (2)	AU2001256344B2 (sr)
BG (1)	BG65968B1 (sr)
BR (1)	BR0111058A (sr)
CA (1)	CA2409869C (sr)
CZ (1)	CZ2003620A3 (sr)
DE (1)	DE50114012D1 (sr)
DK (1)	DK1292607T3 (sr)
EA (1)	EA005623B1 (sr)
EC (2)	ECSP024358A (sr)
ES (1)	ES2307613T3 (sr)
HR (2)	HRP20080423A2 (sr)
HU (1)	HUP0301956A3 (sr)
IL (2)	IL152868A0 (sr)
ME (1)	MEP15608A (sr)
MX (1)	MXPA02011524A (sr)
NO (1)	NO327004B1 (sr)
NZ (1)	NZ522768A (sr)
PL (1)	PL358789A1 (sr)
PT (1)	PT1292607E (sr)
RS (1)	RS50493B (sr)
SK (1)	SK2922003A3 (sr)
UA (1)	UA73988C2 (sr)
WO (1)	WO2001090137A2 (sr)
ZA (1)	ZA200209322B (sr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10218109A1 (de) *	2002-04-23	2003-11-20	Jenapharm Gmbh	Verfahren zum Herstellen von Kristallen, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen
DE10218107A1 (de) *	2002-04-23	2003-11-20	Jenapharm Gmbh	Verfahren zum Herstellen von Kristallen von Steroiden, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen
WO2006078731A2 (en) *	2005-01-18	2006-07-27	Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag	Amorphous and crystalline forms of dorzolamide hydrochloride and processes of making same
US20090054387A1 (en) *	2006-04-18	2009-02-26	Detlef Grawe	Method for preparing 4-[17beta-methoxy-17alpha-methoxymethyl-3-oxestra-4,9-dien-11beta-yl]benzaldehyde (E)-oxime (asoprisnil)
DE102006018888A1 (de) *	2006-04-18	2007-10-25	Bayer Schering Pharma Ag	Verfahren zur Herstellung von 4-[17beta-Methoxy-17alpha-methoxymethyl-3-oxoestra-4,9-dien-11beta-yl]benzaldehyd-(E)-oxims (Asoprisnil)
EP1862468A1 (de) *	2006-06-02	2007-12-05	Bayer Schering Pharma Aktiengesellschaft	Kristallines 11beta-(4-Acetylphenyl)-20,20,21,21,21-pentafluor-17-hydroxy-19-nor-17alpha-pregna-4,9-dien-3-on
DE102009034368A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034366A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034362A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034367A1 (de)	2009-07-20	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034526A1 (de)	2009-07-21	2011-02-10	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de)	2009-07-21	2011-01-27	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102010007722A1 (de)	2010-02-10	2011-08-11	Bayer Schering Pharma Aktiengesellschaft, 13353	Progesteronrezeptorantagonisten
DE102010007719A1 (de)	2010-02-10	2011-08-11	Bayer Schering Pharma Aktiengesellschaft, 13353	Progesteronrezeptorantagonisten

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4332283A1 (de) *	1993-09-20	1995-04-13	Jenapharm Gmbh	Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19610667C2 (de) *	1996-03-08	1998-04-09	Schering Ag	(Z)-11ß-[4-(Dimethylamino)phenyl]17ß-hydroxy-17alpha-(3-hydroxy-1-propenyl)estr-4-en-3-on als kristallines Ansolvat
AU6335600A (en) *	1999-07-29	2001-02-19	Eli Lilly And Company	A novel crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-metho yphenyl)benzo[b]thiophene hydrochloride

2000
- 2000-05-23 EP EP00110887A patent/EP1157996A1/de not_active Withdrawn
2001
- 2001-05-09 PT PT01929632T patent/PT1292607E/pt unknown
- 2001-05-09 SK SK292-2003A patent/SK2922003A3/sk not_active Application Discontinuation
- 2001-05-09 BR BR0111058-6A patent/BR0111058A/pt not_active IP Right Cessation
- 2001-05-09 US US10/296,463 patent/US7799770B2/en active Active
- 2001-05-09 EP EP07115136A patent/EP1862469A2/de not_active Withdrawn
- 2001-05-09 CN CNB018099394A patent/CN100384867C/zh not_active Expired - Fee Related
- 2001-05-09 EP EP01929632A patent/EP1292607B1/de not_active Expired - Lifetime
- 2001-05-09 HU HU0301956A patent/HUP0301956A3/hu unknown
- 2001-05-09 ME MEP-156/08A patent/MEP15608A/xx unknown
- 2001-05-09 CA CA002409869A patent/CA2409869C/en not_active Expired - Lifetime
- 2001-05-09 MX MXPA02011524A patent/MXPA02011524A/es active IP Right Grant
- 2001-05-09 AT AT01929632T patent/ATE397617T1/de not_active IP Right Cessation
- 2001-05-09 RS YUP-887/02A patent/RS50493B/sr unknown
- 2001-05-09 EA EA200201192A patent/EA005623B1/ru not_active IP Right Cessation
- 2001-05-09 IL IL15286801A patent/IL152868A0/xx unknown
- 2001-05-09 DK DK01929632T patent/DK1292607T3/da active
- 2001-05-09 HR HR20080423A patent/HRP20080423A2/xx not_active Application Discontinuation
- 2001-05-09 DE DE50114012T patent/DE50114012D1/de not_active Expired - Lifetime
- 2001-05-09 KR KR1020027015762A patent/KR100553292B1/ko not_active Expired - Fee Related
- 2001-05-09 AU AU2001256344A patent/AU2001256344B2/en not_active Ceased
- 2001-05-09 HR HR20021032A patent/HRP20021032B1/xx not_active IP Right Cessation
- 2001-05-09 WO PCT/EP2001/005237 patent/WO2001090137A2/de not_active Ceased
- 2001-05-09 ES ES01929632T patent/ES2307613T3/es not_active Expired - Lifetime
- 2001-05-09 NZ NZ522768A patent/NZ522768A/en unknown
- 2001-05-09 AU AU5634401A patent/AU5634401A/xx active Pending
- 2001-05-09 CZ CZ2003620A patent/CZ2003620A3/cs unknown
- 2001-05-09 JP JP2001586324A patent/JP2003534350A/ja active Pending
- 2001-05-09 PL PL01358789A patent/PL358789A1/xx not_active IP Right Cessation
- 2001-09-05 UA UA20021210147A patent/UA73988C2/uk unknown
2002
- 2002-11-14 IL IL152868A patent/IL152868A/en not_active IP Right Cessation
- 2002-11-15 ZA ZA200209322A patent/ZA200209322B/en unknown
- 2002-11-22 EC EC2002004358A patent/ECSP024358A/es unknown
- 2002-11-22 NO NO20025613A patent/NO327004B1/no not_active IP Right Cessation
2003
- 2003-02-14 BG BG107557A patent/BG65968B1/bg unknown
2008
- 2008-10-22 EC EC2008004358A patent/ECSP084358A/es unknown

Also Published As

Publication number	Publication date
US7799770B2 (en)	2010-09-21
RS50493B (sr)	2010-03-02
ECSP024358A (es)	2003-03-31
YU88702A (sh)	2006-01-16
EP1862469A2 (de)	2007-12-05
DK1292607T3 (da)	2008-10-13
BG65968B1 (bg)	2010-07-30
HUP0301956A3 (en)	2010-03-29
SK2922003A3 (en)	2003-08-05
EA200201192A1 (ru)	2003-06-26
NO20025613L (no)	2002-11-22
EP1292607B1 (de)	2008-06-04
ATE397617T1 (de)	2008-06-15
KR100553292B1 (ko)	2006-02-22
HRP20021032B1 (hr)	2008-09-30
PL358789A1 (en)	2004-08-23
CN100384867C (zh)	2008-04-30
ZA200209322B (en)	2005-03-10
MEP15608A (en)	2010-06-10
NZ522768A (en)	2005-03-24
JP2003534350A (ja)	2003-11-18
NO20025613D0 (no)	2002-11-22
ES2307613T3 (es)	2008-12-01
WO2001090137A3 (de)	2002-04-04
DE50114012D1 (en)	2008-07-17
CN1430624A (zh)	2003-07-16
CZ2003620A3 (cs)	2003-08-13
CA2409869A1 (en)	2002-11-20
AU5634401A (en)	2001-12-03
UA73988C2 (en)	2005-10-17
EP1292607A2 (de)	2003-03-19
MXPA02011524A (es)	2004-09-10
IL152868A0 (en)	2003-06-24
EA005623B1 (ru)	2005-04-28
PT1292607E (pt)	2008-09-15
HRP20021032A2 (en)	2005-02-28
US20040006241A1 (en)	2004-01-08
IL152868A (en)	2009-08-03
AU2001256344B8 (en)	2001-12-03
HUP0301956A2 (hu)	2003-09-29
KR20030028742A (ko)	2003-04-10
WO2001090137A2 (de)	2001-11-29
CA2409869C (en)	2009-02-03
ECSP084358A (es)	2008-11-27
NO327004B1 (no)	2009-04-06
BR0111058A (pt)	2003-04-15
EP1157996A1 (de)	2001-11-28
AU2001256344B2 (en)	2007-01-25
BG107557A (bg)	2004-01-30

Legal Events

Date	Code	Title	Description
2008-10-31	A1OB	Publication of a patent application
2008-11-05	PNAN	Change of the applicant name, address/residence	Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT, DE
2009-04-17	AIPI	Request for the grant of a patent on the basis of a substantive examination of a patent application
2010-04-27	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20100427 Year of fee payment: 10
2011-11-14	OBST	Application withdrawn

Publication	Publication Date	Title
HRP20080423A2 (en)	2008-10-31	NOVEL SOLID BODY FORMS OF MESOPROGESTIN 11C-[4E-(HYDROXYIMINOMETHYL)-PHENYL]-17α-METHOXYMETYL-17C-METHOXI-ESTRA-4,9-DIEN-3-ONE
NO20071547L (no)	2003-01-24	Nye krystallinske og amorfe former av en triazolo(4,5-D)pyrimidinforbindelse
NO20025821L (no)	2003-02-04	2-aminokarbonyl-9H-purinderivater
DE60108617D1 (de)	2005-03-03	Leitende zementzusammensetzung
NO20050065L (no)	2005-04-22	Kjemiske forbindelser
PL366198A1 (en)	2005-01-24	Novel compounds
NO20023932D0 (no)	2002-08-19	Nye forbindelser
GB0007371D0 (en)	2000-05-17	Chemical compounds
WO2004005212A3 (en)	2004-03-25	Rapid setting cementitious composition
DE60328668D1 (de)	2009-09-17	Hochmolekularergewicht-zusatz für gebrannten gips und und zementzusammensetzungen
NO20020432D0 (no)	2002-01-28	Sementeringsoppslemming med lav tetthet og lav porösitet for oljebrönner og liknende
YU7499A (sh)	2000-03-21	Kristalni oblik 4-[5-metil-3-fenilizoksazol-4-il]benzolsulfonamida
GEP20074125B (en)	2007-06-11	Pyrazolopyridines and methods of making and using the same
NO20045486L (no)	2005-02-02	Nye forbindelser og deres anvendelse
MEP21908A (en)	2010-06-10	Polymorphous form of rimonabant, preparation method and pharmaceutical compositions containing same
IL159289A0 (en)	2004-06-01	Oxytocin agonists
AR038142A1 (es)	2004-12-29	Agonistas del receptor 2 del factor liberador de la corticotropina
ECSP045096A (es)	2004-06-28	Derivados de heteroarilo como ligandos superiores para el receptor de nociceptina orl-1"
NO995431D0 (no)	1999-11-05	Substituerte 3,3-diamino-2-propennitriler, deres fremstilling og anvendelse
TW200610758A (en)	2006-04-01	Alpha crystalline form of strontium ranelate, a process for its preparation, and pharmaceutical compositions containing it
AU2003267551A1 (en)	2004-03-11	Thieno-pyrrole compounds as antagonists of gonadotropin releasing hormone
MX2008001511A (es)	2009-01-07	Mezclas pesticidas que comprenden una fenilsemicarbazona.
DK1322660T3 (da)	2007-01-08	17a-fluoralkylsteroider, fremgangsmåde til deres fremstilling og farmaceutiske sammensætninger, der indeholder disse forbindelser
PL366988A1 (en)	2005-02-07	Gelling sugar and method for producing the same
DE60014096D1 (de)	2004-10-28	Durch 11-beta-aryl-17,17-spirothiolan substituierte steroide