JP2504064B2 - Cosmetics - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial field of application] The present invention makes a crude drug extract stable by adsorbing the crude drug extract on a hydrophobic styrene-based adsorption resin having fine pores, and When the adsorbed styrene-based adsorption resin is used in contact with the skin surface, the herbal medicine extract gradually elutes from the styrene-based adsorption resin due to the temperature and moisture of the skin surface and oil-soluble components, and the performance of the crude drug on the skin The present invention relates to a cosmetic composition containing a styrene-based adsorbent resin that is gradually exhibited.

[Prior art]

Conventionally, crude drugs used in cosmetics include fats and oils, fatty acids,
Those extracted with solvents such as fatty acid esters, alcohols, water and hydrocarbons are used. This crude drug is used alone or in combination of two or more types according to the dosage form, efficacy and purpose of the cosmetic, and is used in a state of being in direct contact with the skin.

[Problems of conventional technology]

The components contained in these crude drug extracts consist of a mixture of a wide range of components such as essential oil components, saponins, tannic acids, alkaloids, sugars, flavonoids,
It is susceptible to changes due to contact with various raw materials in cosmetic preparations, air, light, and moisture. Changes in the components contained in these crude drug extracts appear as deterioration of the preparation and formation and agglomeration of precipitates, which tend to cause problems in the stability of cosmetic preparations.

Among cosmetics, detergents usually contain a large amount of surfactants or solvents, the solubility of the crude drug extract is increased, and they are present as fine particles in the formulation, so the crude drug component has a contact area with other components. Is large and easily reacts with components other than crude drug components. In particular, when an acid or alkaline substance is mixed in the preparation, it is likely to be changed by these substances. Further, when the herbal medicine extract is brought into contact with the skin surface at a high concentration, the skin may be inflamed, and it is often effective to gradually contact it at a low concentration.

Among cleaning agents, scrubbing agents in which various particles are mixed in the formulation are known, and the particles used in this scrubbing agent are inorganic or organic particles molded as powder particles. Also known are granular products obtained by crushing plants, and spherical polystyrene, polyethylene, polypropylene, acrylic, nylon, etc. described in Japanese Patent No. 1346314.

In addition, there are cases where various spherical particles are blended in the preparations of creams and emulsions, which aims to improve the elongation when using creams and the like, and to improve the feel such as smoothness. , A matting effect can be expected in the formulation.
Spherical particles made of plastic such as polystyrene, polyethylene, polypropylene, nylon, and acrylic are known as particles used in such a preparation.

Spherical particles made of these plastics are known to be used in foundations and powders,
It is often used alone or as a composite raw material in which titanium dioxide, fine powders of metals, etc. are attached to it, and the purpose is to improve slippage and elongation during use and protect the skin from external stimuli. And contribute to the improvement of the physical properties of the preparation.

As described above, the spherical particles used for detergents, creams, foundations, etc. are said to be effective in improving the feeling of use such as slippage and elongation during use of the preparation, massage effect by friction, and removal of stains. It was

[Problems to be solved by the invention]

However, when the crude drug extract is added as it is to the formulation containing the above spherical particles, depending on the components contained in the crude drug extract, it may become cloudy or precipitate depending on the reaction with cosmetic raw materials and the solubility in the formulation. It may cause discoloration and often discolor. Further, if a large amount of the essential oil component or the irritating component is temporarily adhered, it may have an adverse effect on the skin and may be undesirable.

[Means for solving problems]

The present inventors have studied to solve the problems of the herbal medicine extract-containing preparation containing the spherical particles in the above-mentioned conventional technology,
As the spherical particles, a hydrophobic styrene-based adsorption resin extract having fine pores is used, and if a form in which a crude drug extract is adsorbed to the spherical styrene-based adsorption resin extract, it is found that the problems in the above-mentioned conventional techniques can be solved very well, As a result of further intensive research based on this new discovery, the present invention has been completed.

That is, the present invention is a powdery or granular cosmetic comprising a mixture of a hydrophobic styrene-based adsorption resin having fine pores and a crude drug extract adsorbed thereto.

The hydrophobic styrenic resin having fine pores used in the present invention is significantly different in function from the generally known spherical plastic particles.

That is, what is generally known as spherical plastic particles is nylon, polyethylene, polystyrene, cross-linked polystyrene, etc., but these spherical plastic particles do not have adsorptivity, and when blended with a crude drug extract, the crude drug is simply added to the resin surface. The extract is attached only and is not occluded in the plastic particles. Therefore, gradually release the crude drug extract targeted by the present invention from the particles,
It is not possible to achieve the object of the present invention that the performance of the crude drug is gradually exerted on the skin. This is
Even if the size of the plastic particles is made small, it does not change, and the phenomenon intended by the present invention cannot be obtained.

Further, as the adsorption resin, there are those having a phenolic or triazine ring, but if the resin matrix is lipophilic, it does not show a specific adsorption performance unlike the styrene-based adsorption resin used in the cosmetics of the present invention. However, such a resin cannot achieve the object of the present invention.

The hydrophobic styrene-based adsorption resin used in the present invention is a styrene-based adsorption resin having a hydrophobic resin matrix, is white and spherical, has excellent chemical resistance, does not have a functional group, and has a specific surface area. It is a resin that is extremely large and selectively adsorbs depending on the substance. Its pore diameter is 140-1,500 nm, and pore volume.
0.4 to 15 ml / g and specific surface area of 400 to 700 m ² / g can be used.

When this is added to the plant extract, the plant extract is temporarily adsorbed. By drying the resin having adsorbed the plant extract, the plant extract (plant extract) is fixed in the styrene resin. The styrenic resin that has adsorbed the plant extract does not separate from the resin even if it is blended in any of powder, granule, and solid preparations, and keeps a stable state. You can
When using these preparations, lipophilic substances containing alcohols, polyhydric alcohols and solvents, surfactants, fragrances, etc. are added, or water is added to powders, granules, water-soluble substances in solids. By dissolving the substance and bringing the resin containing the plant extract into contact with the lipophilic substance, the plant extract elutes again from the resin and gradually dissolves in the formulation,
Keep in contact with the site of use gradually and maintain a low concentration for a long time to remain effective. Further, the styrene-based adsorbent resin also has a property of adsorbing dirt removed from the skin surface, and an effect as a cleaning aid can be expected.

The crude drug used in the present invention can be used in a wide range including those used as Japanese and Chinese crude drugs, Western crude drugs, or folk medicine.

For example, Yamajiko, Huanglian, Huangbai, carrot, orange peel, Chen skin, Large garlic, iris, Safflower, peony skin, ginger, peony, Sawagata, oju, bakumon winter, yellow 耆, apricot kernel, peach kernel, licorice, yamazushi, renja, scent, Tomato ginseng, mulberry bark, ground yellow, our medicine, Yomi, chopsticks, Enmeisou, loquat leaf, light load, ground bud, gold and silver flower, toki, peach leaf, tiger ear grass, Japanese pepper,
Abacus leaf, Peony, Purple silver, Matsufuji, Carmae grass, Carmaco, Hoboku, Matsu, Windbreak, beach windbreak, Enju (Maki), aloe, carrot,
White birch, chamomile, henna, arnica, ton calendula, gentian, geranium, hamamelis, hops, iris, mayonnara, horse chestnut, melissa, hypericum, myrrh, cowberry, papaya, salvia, adachi, juniper, juniper, juniper. Marie, pine, horsetail, eucalyptus, horse chestnut, ginger, yarrow, St. elderberry, St. John's wort, St.
Roman chamomile, cornflower, Neubara, other tea, lemon, orange, lime, rose, lavender, etc.
Extracts of aromatic plants can also be used, and lipophilic substances contained in these plants can be mainly adsorbed.

The solvent for the crude drug extract is preferably an alcohol, a polyhydric alcohol, or a mixed solvent obtained by mixing two or more kinds of solvents with water, and a lipophilic substance, a surfactant, and a fragrance for the mixed solvent. A small amount of pigment, etc. can be added. As the lipophilic substance, fats, waxes, hydrocarbons, fatty acids, esters and the like which are known as raw materials for cosmetics are suitable, and can be used in a state of being dispersed, solubilized or emulsified in the mixed solvent. .

The plants used for cosmetics are generally extracted with a lipophilic or hydrophilic solvent, and this extract is added to a cosmetic preparation for use. These extracts contain various components and are easily affected by other components when mixed in various raw materials, causing discoloration, formation of precipitates, and offensive odor. It is not easy to use because it is apt to be subject to changes in the active ingredients as well as changes in appearance, and because the causative agent of the malodor is extracted at the same time as the active ingredients, the scent is bad.

Since the styrenic adsorption resin used in the present invention adsorbs the malodorous component as well as the active ingredient, the odor of the malodorous substance can be weakened and the intensity of the odor of the active ingredient can be appropriately adjusted. As a result, it becomes possible to utilize a plant which has conventionally been required to use an active ingredient but has a problem of its bad odor in cosmetics, which is also a great advantage of the present invention.

A mixture of ethanol and water (40-90% ethanol) is often used to facilitate the extraction of a wide range of components from crude oils to water-soluble substances in crude drugs. 5 to 50 parts of crude drug is soaked in 100 parts of this solvent, and the crude drug extract obtained by filtering after extraction is stored in a glass pin sealed and stored. It is difficult to keep it stable at room temperature because many foreign substances such as substances and precipitates are recognized, and there are many cases that an offensive odor is generated or the color tone is changed. This can be said for most of the above-mentioned crude drugs, and further compounding several types of crude drugs as necessary elements for the purpose of the formulation makes the ingredients more diverse, lacks stability, and has a certain quality. Therefore, it was extremely difficult to simultaneously extract two or more crude drugs by mixing and extracting them.

According to the present invention, by adding the styrene-based adsorption resin to the crude drug extract, the components of the crude drug can be selectively adsorbed, the contact between the components is reduced, and even if two or more kinds of crude drugs are individually styrene-containing. If they are mixed after being adsorbed on the system-adsorbing resin, they can be kept stable in the formulation for a long period of time without causing mutual reaction of the components.

Furthermore, since the herbal drug components adsorbed on the styrene-based adsorbent resin are removed by heating and drying the adsorbed ethanol and water at the same time, there is little contact between two or more herbal drug components, and the oil solubility is low. When a styrene-based adsorbent resin is added to the preparation containing the above solvent, the active ingredient of the crude drug can be gradually eluted, and it can be adjusted to obtain the same purpose as the preparation obtained by adding the crude drug extract.

In order to allow the crude drug extract to be adsorbed on the styrene-based adsorption resin used in the present invention, the crude drug extract is impregnated in the styrene-based adsorption resin 1 at a ratio of 2 to 3 and dried at room temperature or under heating conditions for 24 hours. To do. The styrene-based adsorption resin thus obtained is in the state as it is or after being coated with a coating-forming material, and then powdered raw material is added thereto to form granules, or a crude drug extract is added to a pre-granulated cosmetic raw material. A desired cosmetic can be produced by blending the contained styrene-based adsorption resin.

Next, in order to show that the skin irritation of the cosmetic containing the styrene-based adsorbent resin adsorbing the crude drug extract according to the present invention was mild, the effect on human skin was tested, and is described below.

(Preparation of sample) To 10 parts of isopropyl alcohol, 70% of ethyl alcohol, and 20% of purified water were added, and the mixture was allowed to stand at room temperature for 24 hours and then filtered. Get. this Is heated to 40 ° C. for 1 hour to remove most of the alcohol, and this is added to 10 parts of white petrolatum and kneaded to obtain a sample A.

on the other hand, Add 1 part of styrene-based adsorption resin to and stir for 30 minutes,
The liquid becomes colorless, The resin that has adsorbed is settled in the lower layer. 2 this resin at 50 ℃
1 part of a styrene-based adsorption resin obtained by drying for an hour is added to 10 parts of white petrolatum and kneaded to obtain a sample B.

The samples A and B obtained as described above were applied to 15 healthy men and women, respectively, in a circular shape with a diameter of 20 mm, applied to the flexion side of the forearm, and after 24 hours, the itch, pain, When the occurrence of redness was examined, the following results were obtained.

In sample A, 23% of people had itching or painful redness, while 67% had redness without feeling itching or pain. In sample B, a little less than 17% of people recognized redness, but itching and pain were not accompanied, and it was proved that the skin irritation of the cosmetic according to the present invention was mild.

Next, the present invention will be described in more detail with reference to Examples.
The present invention is not limited to these examples.

〔Example〕

Example 1 A solvent composed of 10% propylene glycol, 5% glycerin, 70% ethyl alcohol, and 15% purified water with respect to 5 parts of powdered pack Yamajiko (parts represent parts by weight; the same applies to the following examples).
After adding 15 parts and allowing it to stand at room temperature for 24 hours, it is filtered to obtain a brownish brown extract, which is referred to as Yamabushi extract B. This Yamajiko extract
When 2 parts of styrene-based adsorption resin Duolite S-861 (trade name, manufactured by Sumitomo Chemical Co., Ltd.) is added to 3 parts of B3 and stirred for 30 minutes, the resin which adsorbed the Yamajiko extract is precipitated in the lower layer of the extract. This resin is heated and dried at 50 ° C. for 2 hours to obtain a Yamajiko extract adsorption resin.

Next, add 1 to 20 parts of this Yamajiko extract adsorbent resin to 80 to 99 parts of a powdered pack composition made of the following raw materials, and stir and mix them uniformly for 30 minutes with a universal mixing stirrer (manufactured by Sanei Seisakusho). Produces 2 kg of packs.

Clay 50% Talc 20% Zinc oxide 10% Titanium dioxide 5% Jojoba oil 1% Monolauric acid 3% Polyoxyethylene sorbitan glycerin 10% Silicic acid An appropriate amount Perfume An appropriate amount water,
Thoroughly knead with an emulsion or water, apply as a paste to the skin, leave to dry, then rinse with water or hot water.

Example 2 Granular face cleansing agent To 10 parts by weight, 10 parts of a solvent consisting of 10% polyethylene glycol 600, 70% ethyl alcohol and 20% purified water was added, and the mixture was allowed to stand at room temperature for 24 hours and then filtered to obtain a pale yellow extract. The liquid is obtained and designated as Toki Extract B. 1 part of styrene-based adsorption resin Duolite S-861 (trade name, manufactured by Sumitomo Chemical Co., Ltd.) was added to 3 parts of this Toki extract B, and the mixture was stirred for 30 minutes. To do. This resin is dried at 50 ° C. for 2 hours to obtain the Toki extract adsorption resin which is the product of the present invention.

Next, sodium lauryl sulfate 10 parts, lauroyl sarcosine sodium 10 parts, N-lauroylmethyl taurine sodium 10 parts, sorbitol 1.0 part, talc 20 parts, clay 1
A small amount of squalane is added to 0 part of silicic acid anhydride and mixed well, an appropriate amount of water is added and mixed by stirring, and then the mixture is subjected to extrusion granulation, dried and sized to obtain a granular facial cleansing agent base.

In this example, the facial cleansing agent base was described as an example of the wet granulation method which is an extrusion granulation method, but the granulation method is not limited to this, and other methods such as a crushing granulation method and rolling A granulation method, a fluidized bed granulation method or the like can be appropriately selected.

The granulated face cleansing agent according to the present invention is prepared by adding 1 to 20 parts of the above-mentioned Toki extract adsorption resin to 80 to 99 parts of the granular facial cleansing agent base and mixing them to prepare 2 kg of the granular facial cleansing agent. Water is added to 4 to 5 g of the thus obtained granular facial cleanser, and the mixture is kneaded to form a paste, which is washed with water and rinsed with water.

〔The invention's effect〕

As described above, the cosmetic of the present invention is a powdery or granular cosmetic containing a mixture of a hydrophobic styrene-based adsorption resin having fine pores and a crude drug extract adsorbed thereon. The herbal medicine extract stored in the inside of such porous spherical particles is kept stable without eluting the herbal medicine extract in the formulation even when these spherical particles are mixed in the cosmetic preparation, and the skin is not used during use. The crude drug extract gradually elutes from the styrene-based adsorption resin due to surface temperature, oil-soluble components, and water, and the performance of the crude drug is gradually exerted on the skin, and the necessary amount elutes on the skin. Since they come into contact with each other, there is no adverse effect such as inflammation on the skin, and the performance of the herbal medicine is gradually exhibited, thus exhibiting various excellent effects.

Claims (2)

(57) [Claims] 1. A powdery or granular cosmetic comprising a mixture of a hydrophobic styrene-based adsorption resin having fine pores and a crude drug extract adsorbed thereto. 2. A styrene-based adsorption resin having a pore size of 140 to 1,5
The powdery or granular cosmetic material according to claim 1, which is a styrene-based adsorption resin having 00 nm, a pore volume of 0.4 to 1.5 ml / g, and a specific surface area of 400 to 700 m ² / g.