JP3439199B2 - Moisturizing composition - Google Patents

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to the freshness of a medium solution of a wet tissue, a cosmetic agent, a treatment agent for a cosmetic applicator, a bath agent, an additive for a transparent soap, a food additive, a fiber treatment agent, a softener or meat. The present invention relates to a moisturizing composition that imparts film-forming property with excellent moisturizing property to a retaining agent.

[0002]

As a technique for forming a film having a moisturizing effect,
A method of using chitosan as a chitosan salt is known, for example, in Japanese Patent Laid-Open No. 2-105801, a chitosan salt obtained by reacting chitosan with succinic anhydride has a water-retaining effect equivalent to that of hyaluronic acid and is used for cosmetics and pharmaceuticals. It is shown to be effective as a raw material. It is known that acetic acid, lactic acid, malic acid, citric acid or hydrochloric acid other than succinic acid is used as an acid to enhance the moisturizing effect. In addition,
According to 64-62302, a water-soluble chitosan salt having excellent moisturizing properties at pH 6 to 8 is obtained by neutralizing an aqueous solution obtained by adding formic acid, acetic acid, and carbonic acid to chitosan to dissolve it with ammonium carbonate and calcium carbonate. It is said to be effective for food, cosmetics, paper, etc. Moisture-retaining properties are expected from these chitosan solutions, but a strong film is formed by drying and lacks smoothness and flexibility. The cationic nature of chitosan has an allergic sensitization to the skin, and its use on the skin requires attention.

As a technique for improving the formation of a flexible and moisturizing film, a method in which collagen or a peptide is allowed to act on chitosan salt is also known. For example, the present inventors
Japanese Unexamined Patent Publication No. 8-319230 discloses that chitosan is allowed to act on collagen to a chitosan salt composed of ascorbic acid, citric acid, lactic acid, malic acid or the like to form a skin care bath agent having excellent moisturizing properties. However, consumers are not satisfied because the adhesion of the coating film on the treated surface is weak and it is easily removed, and the physical properties are unstable and the decomposition is easy.

[0004]

The technique for forming a flexible moisturizing film using chitosan salt and collagen as raw materials has been attracting attention in the application to cosmetics and fiber treatment agents. Since the acid was released and regenerated into insoluble chitosan, there was a problem of clouding and separation. In underwear and cosmetics, when sweat becomes alkaline, the above reaction causes release of acid and regeneration of chitosan,
There was a problem that caused troubles that stimulate the skin. Further, allergic sensitization has been recognized for the effect of chitosan salt on the skin, and a preventive measure against allergic reaction by incorporating collagen was considered, but the stability of the composition is poor,
Due to the above decomposition, there is a problem that regeneration of acid and cationic chitosan and decomposition of collagen and generation of odor occur.

As described above, the collagen-denatured product of chitosan (chitosan salt / collagen) has attracted attention as a moisturizing film-forming gel state, but it has improved softness and smoothness, and has a moisturizing film-forming property. There is a strong demand for improving the sex, improving the stability of the composition, and preventing the protein from spoiling. In the first place, chitosan is a polymer having a molecular weight of 100,000 or more, and there is a method of solubilizing it as an oligochitosan as well as a method of solubilizing it as a chitosan salt as it is. JP-A-63-22037
According to JP No. 7, chitosan is allowed to act on chitosan to give water-soluble oligochitosan after the reaction. Although it has been proposed to use it, it is inferior in smoothness and adhesion durability of the film formation, and cannot solve the above problems.

[0006]

Means for Solving the Problems The present invention relates to oligochitosan consisting of 2 to 7 glucosamines obtained by cleaving the main chain of chitosan with a chitosan degrading enzyme (chitosanase), and amino acids derived from sericin and / or The present invention provides a film-forming moisturizing composition excellent in smoothness and smoothness, which comprises a sericin protein hydrolyzate. The moisturizing composition according to the present invention can act with an amino acid derived from sericin and / or a sericin protein hydrolyzate to obtain a stable moisturizing composition by using oligochitosan, and when a conventional chitosan salt is used, Thus, the composition can be obtained by decomposing and regenerating the acid and chitosan without causing cloudiness or separation. In addition, since it is specified and used for sericin-derived amino acids and / or sericin protein hydrolysates, it has a high content of serine, glycine, aspartic acid, glutamic acid, etc., and is effective for preventing allergies and rough skin. In addition, there is an advantage that a moisturizing film excellent in smoothness can be obtained which has a slippery feeling unlike the conventional feeling of using collagen.

The moisturizing composition according to the present invention provides a moisturizing film having a smooth feeling on the action side and excellent in smoothness, is excellent in the durability of moisturizing property, and has an effect on rough skin in terms of hygiene and health.
It is a composition having a remarkable effect that it is a moisturizer effective against allergies, atopy and the like. In addition, looking at the application aspect of this composition, since the compounded protein does not release or decompose, it can be supplied as a stable moisturizing composition. Further, since the adsorption of the moisturizing film having the moisturizing property to the skin is durable, the moisturizing effect can be maintained at a high level for a long period of time. In addition, treating textiles with the present moisturizing composition can result in fluffy, soft, moisturizing, and skin-friendly textiles. Freshness-retaining agent for meat such as meat, poultry or fish,
For example, by packaging with a packaging material containing the present composition, the freshness of meat can be maintained for a long time, and the expiration date can be extended.

The blending ratio of the oligochitosan of the present invention to the sericin protein hydrolyzate and / or sericin-derived amino acid is such that the total amount of sericin-derived amino acid and / or sericin protein hydrolyzate is 1 to oligochitosan. , 0.5 to 50 by weight. When the blending ratio is such that the amino acid derived from sericin and / or the hydrolyzate of sericin protein hydrolyzate is 50 or more, the effect of oligochitosan cannot be obtained at all and the protein is apt to be decomposed. When the amount of amino acid derived from sericin and / or hydrolyzed protein of sericin is 0.5 or less, the smooth film-forming effect of denaturing with protein or amino acid cannot be obtained.

Next, the use of the moisturizing composition of the present invention will be described. By containing 0.01% by weight or more of the composition of the present invention in the liquid of a wet tissue, a moisturizing effect with excellent smoothness of the skin after use can be obtained, and it is effective for protecting rough skin and atopy, and for baby and nursing. Expected for use. When used as a makeup applicator, a moisturizing effect can be obtained by impregnating a brush or brush itself made of animal hair or synthetic fiber. Further, in the case of NBR sponge, polyurethane sponge, etc., they should be mixed at the time of manufacturing the latex sponge to contain the composition of the present invention in the sponge material, or after forming the sponge, soak in the composition solution and dry. It is possible to improve the moisturizing property.

Further, by using the moisturizing composition of the present invention, the liquid content and the content of cosmetics are improved, the application to the skin is smoothly performed, and the feel of the skin during use is improved. That is, when the cosmetic contains the composition of the present invention in an amount of 0.01% by weight or more, the moisturizing property of the cosmetic having adhesion and smoothness to the skin can be obtained. Inclusion in hair rinses improves soft, moisturized hair and combs. Furthermore, it is added to a sheet-like cosmetic to obtain skin moisture and smoothness. By including it in a beauty mask or a pack material, the moisturizing effect on the skin can be improved. When it is included in a beauty salt, the skin becomes smooth when used, and it is possible to obtain excellent effects on moisturizing properties and moisturizing the skin. When contained in a bath agent, it has a moisturizing effect on the skin.

Since the present moisturizing composition can be processed into a sheet form, one use portion can be made into one sheet.
Since the present moisturizing composition is stable, it is possible to obtain a transparent soap or transparent cosmetic without causing clouding or separation even when contained in soap. The mixture of oligochitosan and sericin protein hydrolyzate and / or sericin-derived amino acid is dissolved in water and stirred at 70 ° C. for about 30 minutes to obtain a uniform mixture. Preference is given to powdering by spray drying. When trehalose and pullulan are used together in the formulation of the present moisturizing composition, the gel viscosity can be adjusted, the deodorizing function and the cell protecting function can be obtained.

In terms of food, rice, sushi, rice balls,
When it is contained in bread, dried fruits, and pet foods, the moisturizing film effect maintains the moisturizing property, makes it hard to harden, prolongs the shelf life, and improves the umami with amino acids. The combined use of trehalose and pullulan is effective in controlling the physical properties of foods. As fibers and textiles, for example, underwear, bedding, socks, leggings such as pantyhose, towels and the like are treated with the composition according to the invention to give a soft, smooth and plump feel.
Expected as clothing that is hydrophilic and antibacterial and gentle on the skin. It is also possible to use the composition according to the invention as a softener when washing clothes. It has a soft, smooth and fluffy texture and is effective as a household and commercial softener. Trehalose is effective for preventing body odor.
Non-woven fabric or paper containing 0.01% by weight or more of the composition according to the present invention to wrap animal meat, fish meat or poultry to prevent discoloration,
The freshness can be maintained. It was found that the addition of trehalose is more effective in obtaining a deodorizing effect.

The present invention will be described in detail with reference to examples.

[Examples 1 to 3] Oligochitosan, amino acids derived from sericin, and sericin protein hydrolyzate were blended as shown in Table 1, dissolved in purified water, and heat-treated at 70 ° C for 30 minutes, and then with purified water. It was diluted 10 times to obtain a wet tissue medium solution.

[0014]

[Table 1] ───────────────────────────────────                             Example Comparative Example                       1 2 3 1 2 blank       (Part by weight) ───────────────────────────────────   Oligochitosan 1 1 1 0 0 0   Sericin amino acid 2 5 10 0 0 0   Sericin protein ─ ─ 5 5 0 0 0 ───────────────────────────────────   Chitosan lactate ── ── ── 1 1 0   Collagen ─────── 210 100   Purified water 100 100 100 100 100 100 ───────────────────────────────────

A cotton non-woven fabric (weight per unit area: 70 g / m ² ) cut into a size of 15 cm × 20 cm was impregnated with 200% by weight of the medium solution and sealed in an airtight container to obtain a wiped wet tissue for body. The measurement results are shown in Table 2.

[0016]

[Table 2] ───────────────────────────────────                               Example Comparative Example                         1 2 3 1 2 blank ───────────────────────────────────   Moisturizing skin after use 50.0 51.3 52.8 40.3 42.6 31.5   Smoothness of skin after use 5 5 5 3 3 1 ───────────────────────────────────

[Evaluation of moisture retention] in Table 2 is
After the upper arm was wiped with the wet tissue and the skin was dried for 20 minutes, the humidity of the moisture checker MY707S of SCALAR was measured. In addition, [Evaluation of smoothness] is
After drying the skin for 20 minutes, you can feel the smoothness to
(Large), 4, 3, 2, 1 (small) were evaluated in order of 5 ranks.

It was found that the skin after being wiped and dried had an excellent effect on the moisturizing property and smoothness of the skin, as compared with the comparative example.

[0019]

[Examples 4 to 6] The compounded liquids shown in Table 3 were heated with stirring at 70 ° C for 20 minutes to give an NBR sponge, animal hair brush, cotton / underwear, acrylic underwear so that the amount of adhesion was 0.05% by weight. The product was impregnated and dried to measure the moisture retention and smoothness.

[0020]

[Table 3] ───────────────────────────────────                             Example Comparative Example                       4 5 6 3 4 blank       (Part by weight) ───────────────────────────────────   Oligochitosan 1 1 1 0 0 0   Sericin amino acid 4 5 12 0 0 0   Sericin protein 0 5 8 0 0 0 0 ───────────────────────────────────   Chitosan lactate 0 0 0 1 1 1 0   Collagen 0 0 0 5 0   Purified water 100 100 100 100 100 100 ───────────────────────────────────

Table 4 shows the measurement results.

[0022]

[Table 4] ───────────────────────────────────                                 Example Comparative Example                           4 5 6 3 4 blank ───────────────────────────────────   Moisturizing NBR sponge 35.0 35.9 37.6 20.8 21.5 2           Animal hair brush 40.1 41.3 42.3 20.4 21.8 10           Cotton underwear 40.6 40.9 42.1 21.7 22.3 15         Acrylic underwear 35.0 36.4 37.9 18.5 18.8 2 ───────────────────────────────────   Smoothness NBR sponge 5 5 5 3 3 1           Animal hair brush 5 5 5 3 3 1           Cotton / Underwear 5 5 5 3 3 1           Acrylic underwear 5 5 5 3 3 1 ───────────────────────────────────

It has been found that the moisturizing composition of the present invention markedly improves the moisturizing effect and smoothness in NBR sponges, animal hair brushes, cotton underwear and acrylic underwear.

[0024]

Example 7 When the composition liquid of Table 3 in Example 4 was used to contain 0.05% by weight in a transparent soap composition, a soap having excellent transparency could be obtained.
Also, after using the obtained transparent soap, excellent smoothness and moisturization were obtained on the skin.

[0025]

Example 8 Using the composition liquid of Table 3 in Example 4, a thin paper made of pulp was coated with the composition liquid of Example 4 shown in Table 3 to prepare a wrapping paper. Thawed tuna was wrapped with this wrapping paper and stored in a refrigerator. With the usual wrapping paper during storage, the fillets discolored immediately, but with the wrapping paper according to the present invention, the discoloration did not occur even after 1 week,
The freshness preservation effect was obtained.

[0026]

INDUSTRIAL APPLICABILITY The moisturizing composition of the present invention is a stable moisturizing composition that acts with an amino acid or protein hydrolyzate by using oligochitosan, and decomposes like a conventional chitosan salt. It is a composition that regenerates acid and chitosan without causing clouding or separation. In addition, serine, glycine, aspartic acid, since sericin-derived amino acid, since it is used by specifically specifying sericin protein hydrolyzate,
It has a high content of glutamic acid and is effective in preventing allergies and rough skin. At the same time, it is possible to obtain a moisturizing film having a smoothness which is smooth and has a feeling different from that obtained by using conventional collagen. The moisturizing composition of the present invention is a medium solution of wet tissue, cosmetics, treatment agent for makeup applicator, bath agent, additive for transparent soap, food additive, fiber treatment agent, softener, or meat, poultry or It can be used as a freshness-keeping agent for fish meat.

─────────────────────────────────────────────────── ─── Continued Front Page (51) Int.Cl. ⁷ Identification Code FI A61K 7/48 A61K 7/48 7/50 7/50 C11D 9/04 C11D 9/04 9/30 9/30 9/38 9 / 38 9/40 9/40 D06M 15/03 D06M 15/03 15/15 15/15 (72) Inventor Momoki Nakagawa 3-20-4-204 Kyojima, Sumida-ku, Tokyo 2F, 5F (56) References JP 62-273905 (JP, A) JP 62-30103 (JP, A) JP 2001-64148 (JP, A) JP 2001-39999 (JP, A) JP 9-228249 (JP , A) JP 2000-191445 (JP, A) JP 8-60198 (JP, A) JP 9-132871 (JP, A) JP 10-165327 (JP, A) JP 3 -205011 (JP, A) JP 7-189170 (JP, A) JP 2001-81027 (JP, A) Utility model registration 3047587 (JP, U) (58)査the field (Int.Cl. ^7, DB name) C09K 3/00 A23L 1/10 A23L 3/3526 501 A23L 3/3562 A61K 7/00 - 7/50 C11D 9/04 - 9/60 D06M 15/03 -15/15

Claims (2)

(57) [Claims] 1. A chitosan degrading enzyme (chitosanase)
1 part by weight of oligochitosan consisting of 2 to 7 of glucosamine obtained by cleaving the main chain of chitosan with (2)
A moisturizing composition comprising 0.5 to 50 parts by weight of a sericin-derived protein hydrolyzate mixture containing an amino acid derived from sericin in an amount of 1/2 to 2/3 of the mixture excluding oligochitosan. 2. A medium solution of a wet tissue, a cosmetic, a treatment agent for a cosmetic applicator, a bath agent, an additive for a transparent soap, a food additive, comprising the moisturizing composition of claim 1.
Texturing agent, softener, or freshness-retaining agent for meat, poultry or fish.