JP5113371B2 - Hydrolyzate of water-soluble polysaccharide derived from white jellyfish, antioxidant containing the same, cosmetic or skin external preparation, food - Google Patents

Description

  TECHNICAL FIELD The present invention relates to a hydrolyzate of a water-soluble polysaccharide extracted from a fruit body of a mushroom of the family Asteraceae, an antioxidant, a cosmetic or skin external preparation, and a food containing the same.

Conventionally, water-soluble polysaccharides extracted from white jellyfish fruit bodies have been widely used as cosmetic raw materials that have a high moisturizing effect and can impart a smooth and excellent feeling of use (Patent Document 1). This water-soluble polysaccharide is known to have various physiological activities, and has an effect of promoting collagen generation, MMP (matrix protease) inhibition such as collagenase, anti-inflammatory agent and moisturizing property of stratum corneum. Important NMF production promoting action, ceramide synthesis promoting action and the like are disclosed (Patent Documents 2 to 6).
Furthermore, an anti-inflammatory agent having a hydrophobic group introduced as a derivative of the component derived from white jellyfish is also disclosed (Patent Document 7).

  On the other hand, various causes of skin troubles have been elucidated in recent years. For example, active oxygen and free radicals are known to cause damage to living tissues and cells, and thus cause various diseases and aging. . In an environment where active oxygen is generated in the skin tissue, such as stimulation by ultraviolet rays or chemical substances, an excellent antioxidant capable of suppressing or preventing the action of active oxygen and free radicals generated by these has been desired. .

However, with regard to antioxidant activity, this water-soluble polysaccharide does not have a sufficient effect, and because this polysaccharide has an extremely large molecular weight, the viscosity becomes too high above a certain concentration, and cosmetics, skin There has also been a problem that it becomes difficult to use it for external preparations, foods and the like.

JP 2005-330257 A JP 2006-131558 A JP 2006-182695 A JP 2006-111545 A JP 2006-124350 A JP 2006-111560 A JP 2005-306814 A

  The present invention provides an antioxidant that is easy to use in cosmetics, external preparations for skin, foods, etc. and has high antioxidant activity, and a cosmetic or external preparation for skin characterized by containing the same, and food. This is the issue.

  As a result of intensive studies to solve the above problems, the present inventors have found that the antioxidant activity is significantly increased by hydrolyzing the water-soluble polysaccharide with an acid to reduce the molecular weight. Completed the invention. That is, the present invention provides a hydrolyzate of a water-soluble polysaccharide extracted from the fruit body of a jellyfish mushroom, and an antioxidant, a cosmetic or skin external preparation, and a food containing the same. Is.

  In the present specification, the term “antioxidant” means that in order to prevent or suppress these damages caused by active oxygen and free radicals, the generated active oxygen and free radicals are used in addition to the action of preventing their occurrence. It is to be interpreted in the broadest sense, including supplementation or deletion. The active oxygen includes superoxide, hydrogen peroxide, hydroxy radical, singlet oxygen and the like. The free radical means a molecule or atom containing one or more unpaired electrons, and includes superoxide, hydroxy radical, DPPH (diphenylpicrylhydrazide) and the like.

  By using the present invention, a hydrolyzate having low viscosity, excellent operability, and greatly increased antioxidant activity can be obtained. Moreover, cosmetics or a skin external preparation with high antioxidant activity, and a foodstuff are obtained by containing this hydrolyzate.

  As the water-soluble polysaccharide used in the present invention, a water-soluble polysaccharide extracted from the fruit body of the jellyfish family Tremella fuciformis Berk. With water or a mixture of water and a water-soluble solvent can be used. Depending on the type of solvent used for extraction, extraction temperature, extraction time, etc., water-soluble polysaccharides having different average molecular weights can be obtained. This water-soluble polysaccharide is sold as a product by Nippon Seika Co., Ltd. (trade name: Tremoist-TP).

  The hydrolysis method used in the present invention is not particularly limited, and a known method can be used. For example, it can be obtained by hydrolysis with an acid. Examples of the acid used include inorganic acids such as hydrochloric acid, phosphoric acid, sulfuric acid and nitric acid; organic acids such as p-toluenesulfonic acid and methanesulfonic acid. Although the usage-amount of an acid changes with the density | concentrations and kind of acid to be used, for example, the acid density | concentration is used at about 0.5-50 weight%. The average molecular weight of the hydrolyzed product can be adjusted by appropriately selecting the amount, concentration, and type of acid used.

  The weight average molecular weight of the hydrolyzate obtained in the present invention is preferably 1000 to 100,000, most preferably 3000 to 20,000. When the weight average molecular weight is larger than 100,000, the antioxidant activity is insufficient. The weight average molecular weight referred to in the present invention is a weight average molecular weight in a gel permeation chromatogram (GPC) measured using water as a solvent and polyethylene oxide having a known molecular weight as a standard substance. The hydrolyzate obtained in the present invention may be purified by a known method such as dialysis, ultrafiltration, gel filtration, reprecipitation and the like.

The form of the hydrolyzate of the water-soluble polysaccharide obtained in the present invention is not particularly limited, and examples thereof include various forms such as an aqueous solution (liquid form), powder form, and granular form.

  The hydrolyzate obtained in the present invention is characterized by high antioxidant activity when hydrolyzed, and can be used as an antioxidant. Although it can be used as it is as an antioxidant, it may be combined with other antioxidants. The content in the antioxidant is 0.001% to 100% by weight, more preferably 0.01% to 80%. Moreover, as long as it does not interfere with the antioxidant activity of the hydrolyzate obtained in the present invention, other components are not particularly limited, and can be appropriately selected from known components according to the purpose.

Although the hydrolyzate of this invention can be used for various uses, it is preferable to use it for cosmetics, a skin external preparation, or a foodstuff, and it is especially preferable to use it for cosmetics or a skin external preparation. When using the hydrolyzate of this invention for cosmetics or a skin external preparation, content in these becomes like this. Preferably it is 0.001 to 50 weight%, More preferably, it is 0.01 to 20 weight%. is there. The form of the food is not particularly limited, such as tablets, capsules, powders, syrups, drinks, etc. The content when used in foods is preferably 0.001 wt% to 100 wt%, more Preferably it is 0.1 weight%-100 weight%. If it exists in this range, the said hydrolyzate can be mix | blended stably and a high antioxidant effect can be exhibited. Moreover, when using this hydrolyzate as a solution, as long as content of the hydrolyzate which is a solute is in the said range, the solution density | concentration will not be limited at all.

  In the cosmetic or skin external preparation of the present invention, components other than the hydrolyzate, such as water, oily base, moisturizer, feel improver, surfactant, polymer, thickener / gelator, solvent , Propellant, antioxidant, reducing agent, antiseptic, antibacterial agent, chelating agent, pH adjuster, acid, alkali, powder, inorganic salt, UV absorber, whitening agent, vitamins and derivatives thereof, anti-inflammatory agent , Anti-inflammatory agent, hair growth agent, blood circulation promoter, stimulant, hormones, anti-wrinkle agent, anti-aging agent, squeeze agent, cooling sensation agent, warming sensation agent, wound healing promoter, stimulation relieving agent, analgesic agent, Cell activator, plant / animal / microbe extract, antipruritic agent, exfoliating / dissolving agent, antiperspirant, refreshing agent, astringent, enzyme, nucleic acid, fragrance, pigment, colorant, dye, pigment It is preferable to contain 2 or more types. The cosmetic or skin external preparation of the present invention can exhibit the functions necessary for the cosmetic or external skin preparation by containing one or more selected from these. The amount of these components varies depending on the type of component, but is preferably 0.0001% by weight to 99.999% by weight per component, more preferably 0.001% by weight to 99.99% by weight per component. It is. In the cosmetic and skin external preparation of the present invention, two or more kinds of ingredients that are known to be used in cosmetics or skin external preparations are usually blended, but the combination, blending ratio and blending amount are well-known. It can be contained in combination and in a mixing ratio / amount.

  These additive components will be described in more detail. Examples of water that can be blended in the cosmetic or skin external preparation of the present invention include normal water, purified water, hard water, soft water, natural water, deep sea water, electrolytic alkaline ionized water, electrolytic acidic ionized water, and ionized water. Cluster water is preferable.

Examples of oily bases include cetanol, myristyl alcohol, oleyl alcohol, lauryl alcohol, cetostearyl alcohol, stearyl alcohol, aralkyl alcohol, behenyl alcohol, jojoba alcohol, chimyl alcohol, ceralkyl alcohol, batyl alcohol, hexyldecanol, isostearyl alcohol, Higher alcohols such as 2-octyldodecanol and dimer diol; aralkyl alcohols and derivatives such as benzyl alcohol; lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, behenic acid, undecylenic acid, 12-hydroxystearic acid, Palmitooleic acid, oleic acid, linoleic acid, linolenic acid, erucic acid, docosahexaenoic acid, eicosapentaenoic acid, isohexa Higher fatty acids such as canic acid, antiisohenicosanoic acid, long-chain branched fatty acid, dimer acid, hydrogenated dimer acid and metal soaps such as aluminum salts, calcium salts, magnesium salts, zinc salts, sodium salts and potassium salts And nitrogen-containing derivatives such as ethanolamine salts and amides; liquid paraffin (mineral oil), heavy liquid isoparaffin, light liquid isoparaffin, α-olefin oligomer, polyisobutene, hydrogenated polyisobutene, polybutene, squalane , Olive-derived squalane, squalene, petroleum jelly, solid paraffin and other carbides; candelilla wax, carnauba wax, rice wax, waxy wax, beeswax, montan wax, ozokerite, ceresin, paraffin wax, microcrystalline Waxes such as wax, petrolatum, Fischer-Tropsch wax, polyethylene wax, ethylene propylene copolymer; palm oil, palm oil, palm kernel oil, safflower oil, olive oil, castor oil, avocado oil, sesame oil, tea oil, evening primrose oil, Wheat germ oil, macadamia nut oil, hazelnut oil, kukui nut oil, rosehip oil, meadow foam oil, persic oil, tea tree oil, mint oil, corn oil, rapeseed oil, sunflower oil, wheat germ oil, linseed oil, cottonseed oil, soybean oil Vegetable oils such as peanut oil, rice bran oil, cacao butter, shea butter, hydrogenated palm oil, hydrogenated castor oil, jojoba oil, hydrogenated jojoba oil; beef tallow, milk fat, horse fat, egg yolk oil, mink oil, turtle Animal fats and oils such as oil; movement of whale wax, lanolin, orange luffy oil, etc. Waxes: liquid lanolin, reduced lanolin, adsorption-purified lanolin, lanolin acetate, lanolin acetate, hydroxy lanolin, polyoxyethylene lanolin, lanolin fatty acid, hard lanolin fatty acid, lanolin alcohol, lanolin alcohol acetate, acetic acid (cetyl lanolyl) ester Lanolins such as: lecithin, phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, sphingophospholipids such as sphingomyelin, phospholipids such as phosphatidic acid, lysolecithin; hydrogenated soybean phospholipid, partially hydrogenated soybean Phospholipids such as phospholipids, hydrogenated egg yolk phospholipids, partially hydrogenated egg yolk phospholipids; cholesterol, dihydrocholesterol, lanosterol Sterols such as dihydrolanosterol, phytosterol and cholic acid; sapogenins; saponins; cholesteryl acetate, cholesteryl nonanoate, cholesteryl isostearate, cholesteryl isostearate, cholesteryl oleate, di-N-lauroyl-L-glutamate (cholesteryl / behenyl / Octyldodecyl), N-lauroyl-L-glutamate di (cholesteryl / octyldodecyl), N-lauroyl-L-glutamate di (phytosteryl / behenyl / octyldodecyl), N-lauroyl-L-glutamate di (phytosteryl / octyldodecyl) , Acyl sarcosine alkyl esters such as N-lauroyl sarcosine isopropyl, cholesteryl 12-hydroxystearate, macadamia nut oil fatty acid cholesterol Sterol esters such as ril, macadamia nut oil fatty acid phytosteryl, phytosteryl isostearate, soft lanolin fatty acid cholesteryl, hard lanolin fatty acid cholesteryl, long-chain branched fatty acid cholesteryl, long-chain α-hydroxy fatty acid cholesteryl; phospholipid / cholesterol complex, phospholipid / Lipid complexes such as phytosterol complex; octyldodecyl myristate, hexyldecyl myristate, octyldodecyl isostearate, cetyl paritate, octyldodecyl palmitate, cetyl octoate, hexyldecyl octoate, isotridecyl isononanoate, isononanoyl isononanoate, Octyl isononanoate, isotridecyl isononanoate, isodecyl neopentanoate, isotridecyl neopentanoate, neopenta Isostearyl acid, octyldodecyl neodecanoate, oleyl oleate, octyldodecyl oleate, octyldodecyl ricinoleate, octyldodecyl lanolinate, hexyldecyl dimethyloctanoate, octyldodecyl erucate, isostearic acid hydrogenated castor oil, ethyl oleate, avocado Mono-alcohol carboxylates such as oil fatty acid ethyl, isopropyl myristate, isopropyl palmitate, octyl palmitate, isopropyl isostearate, lanolin fatty acid isopropyl, triethyl citrate; cetyl lactate, diisostearyl malate, hydrogenated monoisostearate Oxyesters such as castor oil; glyceryl trioctanoate, glyceryl trioleate, glyceryl triisostearate, diiso Glyceryl stearate, tri (caprylic acid / capric acid) glyceryl, tri (caprylic acid / capric acid / myristic acid / stearic acid) glyceryl, hydrogenated rosin triglyceride (hydrogenated ester gum), rosin triglyceride (ester gum), behenic acid Glyceryl eicosandioate, (tetradecanedioic acid / eicosandioic acid) glyceryl, (tetradecanedioic acid / eicosandioic acid) polyglyceryl-10, trimethylolpropane trioctanoate, trimethylolpropane triisostearate, neopentyl glycol dioctanoate, dicapric acid Neopentyl glycol, 2-butyl-2-ethyl-1,3-propanediol dioctanoate, 3-methyl-1,5-pentanediol dineopentanoate, 2,4-diethyl dineopentanoate 1,5-pentanediol, propylene glycol dioleate, pentaerythrityl tetraoctanoate, hydrogenated rosin pentaerythrityl, ditrimethylolpropane triethylhexanoate, (isostearic acid / sebacic acid) ditrimethylolpropane, pentaerythrityl triethylhexanoate , (Hydroxystearic acid / stearic acid / rosinic acid) dipentaerythrityl, diglyceryl diisostearate, polyglyceryl tetraisostearate, polyglyceryl nonaisostearate-10, deca (erucic acid / isostearic acid / ricinoleic acid) polyglyceryl-8, (hexyldecanoic acid / Multivalent alcohols such as sebacic acid) diglyceryl oligoester, glycol distearate (ethylene glycol distearate) Fatty acid esters: diisopropyl dimerlinoleate diisopropyl, dimer dilinoleate diisostearyl, dimer dilinoleate di (isostearyl / phytosteryl), dimer dilinoleate (phytosteryl / behenyl), dimer dilinoleate (phytosteryl / isostearyl / Cetyl / stearyl / behenyl), dimer dilinoleic acid dimer dilinoleyl, dimer dilinoleic acid dimer dilinoleyl bis (phytosteryl / behenyl / isostearyl), diisostearate dimer dilinoleyl, dimer dilinoleyl hydrogenated rosin condensate , Dimer linoleic acid hydrogenated castor oil, dimer acid or dimer diol derivative such as hydroxyalkyl dimer linoleyl ether; coconut oil fatty acid monoethanolamide (cocamide) MEA), coconut oil fatty acid diethanolamide (cocamide DEA), lauric acid monoethanolamide (lauramide MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid monoethanolamide (partamide MEA) ), Fatty acid alkanolamides such as palmitic acid diethanolamide (partamide DEA), coconut oil fatty acid methylethanolamide (cocamide methyl MEA); dimethicone (dimethylpolysiloxane), highly polymerized dimethicone (highly polymerized dimethylpolysiloxane), cyclomethicone (cyclic) Dimethylsiloxane, decamethylcyclopentasiloxane), phenyltrimethicone, diphenyldimethicone, phenyldimethicone, stearoxypropyl Methylamine, (aminoethylaminopropyl methicone / dimethicone) copolymer, dimethiconol, dimethiconol crosspolymer, silicone resin, silicone rubber, amino-modified silicone such as aminopropyl dimethicone and amodimethicone, cation-modified silicone, polyether modification such as dimethicone copolyol Silicone, polyglycerin modified silicone, sugar modified silicone, carboxylic acid modified silicone, phosphoric acid modified silicone, sulfuric acid modified silicone, alkyl modified silicone, fatty acid modified silicone, alkyl ether modified silicone, amino acid modified silicone, peptide modified silicone, fluorine modified silicone, Cationic modified and polyether modified silicone, amino modified and polyether modified silicone, alkyl modified and Polyether-modified silicone, silicones such as polysiloxane polyoxyalkylene copolymer; perfluorodecane, perfluorooctane, fluorine-based oils such as perfluoropolyether may be mentioned as preferred.

As the humectant / feel improver, glycerin, 1,3-butylene glycol, propylene glycol, 3-methyl-1,3-butanediol, 1,3-propanediol, 2-methyl-1,3-propanediol, Polyols such as trimethylolpropane, pentaerythritol, hexylene glycol, diglycerin, polyglycerin, diethylene glycol, polyethylene glycol, dipropylene glycol, polypropylene glycol, ethylene glycol / propylene glycol copolymer and polymers thereof; diethylene glycol monoethyl ether (Ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene glycol dibutyl ether, etc. (Eicosandioic acid / tetradecandioic acid) water-soluble esters such as polyglyceryl-10 esters; sugar alcohols such as sorbitol, xylitol, erythritol, mannitol, maltitol; glucose, fructose, galactose, mannose, threose, xylose Arabinose, fucose, ribose, deoxyribose, maltose, trehalose, lactose, raffinose, gluconic acid, glucuronic acid, β-glucan, chitin, chitosan, heparin and derivatives, pectin, arabinogalactan, dextrin, dextran, glycogen, ethyl glucoside Sugars such as glucosyl ethyl methacrylate polymer or copolymer; and derivatives thereof; hyaluronic acid, sodium hyaluronate; chondroitin sulfate sodium Thorium; mucoitin sulfate, caroline sulfate, keratosulfate, dermatan sulfate; white jellyfish extract; fucoidan; naturally occurring polysaccharides such as tuberose polysaccharide and derivatives thereof; organic acids such as citric acid, tartaric acid and lactic acid and salts thereof; urea; 2-pyrrolidone-5-carboxylic acid and salts thereof such as sodium; betaine (trimethylglycine), proline, hydroxyproline, arginine, lysine, serine, glycine, alanine, phenylalanine, tyrosine, β-alanine, threonine, glutamic acid, glutamine, Amino acids and their salts such as asparagine, aspartic acid, cysteine, cystine, methionine, leucine, isoleucine, valine, tryptophan, histidine, taurine; collagen, fish-derived collagen, atelocollagen, gelatin Elastin, collagen degrading peptide, hydrolyzed collagen, hydroxypropylammonium chloride hydrolyzed collagen, elastin degrading peptide, keratin degrading peptide, hydrolyzed keratin, conchiolin degrading peptide, hydrolyzed conchiolin, silk proteolytic peptide, hydrolyzed silk, lauroyl hydrolyzing Protein peptides such as silk sodium, soybean proteolytic peptide, wheat proteolytic peptide, hydrolyzed wheat protein, casein degrading peptide, acylated peptide and derivatives thereof; acylated peptides such as palmitoyl oligopeptide, palmitoyl pentapeptide, palmitoyl tetrapeptide Silylated peptides: Lactic acid bacteria culture solution, yeast extract, eggshell membrane protein, bovine submandibular gland mucin, hypotaurine, sesameignan glycoside, glutathione, a Lubumin, whey; choline chloride, phosphorylcholine; placenta extract, aerostin, collagen, aloe extract, hamamelis water, loofah water, chamomile extract, licorice extract, comfrey extract, silk extract, Izayoi rose extract, yarrow extract, eucalyptus extract Ceramides, such as animal and plant extract components such as merirot extract, natural ceramide (types 1, 2, 3, 4, 5, 6), hydroxyceramide, pseudoceramide, glycosphingolipid, ceramide and sugar ceramide-containing extract It is mentioned as preferable.

Preferred examples of the surfactant include an anionic surfactant, a nonionic surfactant, a cationic surfactant, an amphoteric surfactant, and a polymer surfactant. There is no restriction | limiting in particular in HLB of surfactant, It can use from about 1 low thing to about 20 high thing, It is also preferable to combine what has low and high HLB. Examples of preferable surfactants include fatty acid salts such as potassium laurate and potassium myristate; alkyl sulfates such as sodium lauryl sulfate, triethanolamine lauryl sulfate, and ammonium lauryl sulfate; laureth Polyoxyethylene alkyl sulfates such as sodium sulfate and laureth sulfate triethanolamine; cocoyl methyl taurine sodium, cocoyl methyl taurine potassium, lauroyl methyl taurine sodium, myristoyl methyl taurine sodium, lauroyl methyl alanine sodium, lauroyl sarcosine sodium, lauroyl sarcosine triethanol Acyl N-methyl amino acid salts such as amines and sodium methylalanine lauroylglutamate; Cocoyl Glue Acyl amino acid salts such as sodium minate, triethanolamine cocoyl glutamate, sodium lauroyl glutamate, sodium myristoyl glutamate, sodium stearoyl glutamate, ditriethanolamine palmitoyl aspartate, cocoylalanine triethanolamine; polyoxyethylene alkyl ethers such as sodium laureth acetate Acetic acid salt; Succinic acid ester salt such as sodium lauroyl monoethanolamide succinate; Fatty acid alkanolamide ether carboxylate; Acyl lactate; Polyoxyethylene fatty amine sulfate; Fatty acid alkanolamide sulfate; Hardened coconut oil fatty acid sodium glyceryl sulfate Fatty acid glyceride sulfate such as alkylbenzene polyoxyethylene sulfate; α-olefin Olefin sulfonates such as sodium sulfonate; alkylsulfosuccinates such as disodium lauryl sulfosuccinate and dioctyl sodium sulfosuccinate; disodium laureth sulfosuccinate, monolauroyl monoethanolamide polyoxyethylene sodium sulfosuccinate, lauryl polypropylene glycol sulfosuccinic acid Alkyl ether sulfosuccinates such as sodium; alkylbenzene sulfonates such as sodium tetradecylbenzenesulfonate and tetraethanolamine tetraethanol; alkylnaphthalenesulfonates; alkanesulfonates; α-sulfo fatty acid methyl ester salts; Acyl isethionate; alkyl glycidyl ether sulfonate; alkyl sulfoacetate; laurethrin Alkyl ether phosphates such as sodium, sodium dilaureth phosphate, sodium trilaureth phosphate, sodium monooles phosphate; alkyl phosphate salts such as potassium lauryl phosphate; sodium caseinate; alkyl aryl ether phosphate; fatty acid amide ether phosphorus Phospholipids such as phosphatidylglycerol, phosphatidylinositol, and phosphatidic acid; silicone anionic surfactants such as carboxylic acid-modified silicone, phosphate-modified silicone, and sulfate-modified silicone; and nonionic surfactants, laureth (Polyoxyethylene lauryl ether), ceteth (polyoxyethylene cetyl ether), steareth (polyoxyethylene stearyl ether), behenez (polyoxyethylene) Nbehenyl ethers), isosteares (polyoxyethylene isostearyl ethers), octyldecesses (polyoxyethylene octyldodecyl ethers) and other polyoxyethylene alkyl ethers with various polyoxyethylene addition numbers; polyoxyethylene alkylphenyl ethers; Polyoxyethylene hydrogenated castor oil, polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil monoisostearate, polyoxyethylene hydrogenated castor oil triisostearate, polyoxyethylene hydrogenated castor oil monopyroglutamic acid monoisostearate diester, poly Castor oil such as oxyethylene hydrogenated castor oil maleic acid and hydrogenated castor oil derivatives; polyoxyethylene phytosterol; polyoxyethylene cholesterol; polyoxy Polyoxyethylene lanolin; polyoxyethylene reduced lanolin; polyoxyethylene polyoxypropylene cetyl ether, polyoxyethylene polyoxypropylene 2-decyltetradecyl ether, polyoxyethylene polyoxypropylene monobutyl ether, polyoxyethylene lanolin; Oxyethylene / polyoxypropylene hydrogenated lanolin, polyoxyethylene / polyoxypropylene alkyl ethers such as polyoxyethylene / polyoxypropylene glycerin ether; polyoxyethylene / polyoxypropylene glycol; (poly) such as PPG-9 diglyceryl Glycerin polyoxypropylene glycol; glyceryl stearate, glyceryl isostearate, glyceryl palmitate, myristate group Glyceryl fatty acid partial esters such as ceryl, glyceryl oleate, glyceryl coconut fatty acid, mono-cotton oil fatty acid glycerin, glyceryl monoerucate, glyceryl sesquioleate, α, α'-oleic acid pyroglutamic acid glycerin, monostearic acid glycerin malic acid; Polyglyceryl stearate-2, 3, 4, 5, 6, 8, 10, polyglyceryl distearate-6, 10, polyglyceryl tristearate, polyglyceryl decastearate-10, polyglyceryl isostearate -2, 3, 4, 5, 6, 8, 10, diglycostyl diisostearate (diglyceryl diisostearate), 3, 10, polyglyceryl-2 triisostearate, polyglyceryl tetraisostearate Ril-2, polyglyceryl-10 decaisostearate, polyglyceryl-2 oleate, 3,4, 5,6, 8,8, dioleate polyglyceryl-6, trioleate polyglyceryl-2, dekaoleic acid Polyglyceryl fatty acid esters such as polyglyceryl-10; ethylene glycol monofatty acid esters such as ethylene glycol monostearate; propylene glycol monofatty acid esters such as propylene glycol monostearate; pentaerythritol partial fatty acid esters; sorbitol partial fatty acid esters; maltitol moieties Fatty acid ester; maltitol ether; sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monos Sorbitan fatty acid esters such as allate, sorbitan sesquioleate, sorbitan trioleate, diglycerol sorbitan penta-2-ethylhexylate, diglycerol sorbitan tetra-2-ethylhexylate; sucrose fatty acid ester, methyl glucoside fatty acid ester, trehalose undecylenate, etc. Partial derivatives of sugar derivatives; alkyl glucosides such as caprylyl glucoside; alkyl polyglycosides; lanolin alcohols; reduced lanolin; polyoxyethylene distearate, polyethylene glycol diisostearate, polyoxyethylene monooleate, polyoxyethylene di- Polyoxyethylene fatty acid mono- and diesters such as oleate; polyoxyethylene propylene glycol fatty acid ester; polyoxyethylene Polyoxyethylene glycerin fatty acid esters such as polyoxyethylene monooleate such as polyglycerin monostearate, polyoxyethylene glycerin monoisostearate, polyoxyethylene glycerin triisostearate; polyoxyethylene sorbitan monooleate, polyoxy Polyoxyethylene sorbitan fatty acid esters such as ethylene sorbitan monostearate, polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan tetraoleate; polyoxyethylene sorbitol monolaurate, polyoxyethylene sorbitol monooleate, polyoxyethylene sorbitol penta Polyoxyethylene sorbitol fatty acid esters such as oleate and polyoxyethylene sorbitol monostearate Polyoxyethylene methyl glucoside fatty acid ester; Polyoxyethylene alkyl ether fatty acid ester; Polyoxyethylene animal and vegetable oils such as polyoxyethylene sorbitol beeswax; Alkyl such as isostearyl glyceryl ether, chimyl alcohol, ceralkyl alcohol, batyl alcohol Glyceryl ethers; polyhydric alcohol alkyl ethers; polyoxyethylene alkylamines; tetrapolyoxyethylene / tetrapolyoxypropylene-ethylenediamine condensates; natural surfactants such as saponins and sophorolipids; polyoxyethylene fatty acid amides; coconut oil Fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanolamide (cocamide DEA), lauric acid monoethanolamide (laura) De MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid monoethanolamide (partamide MEA), palmitic acid diethanolamide (partamide DEA), palm oil fatty acid methyl ethanolamide (cocamidomethyl) Fatty acid alkanolamides such as MEA); alkyldimethylamine oxides such as lauramine oxide, cocamamine oxide, stearamine oxide, and behenamine oxide; alkylethoxydimethylamine oxide; polyoxyethylene alkyl mercaptan; poly such as dimethicone copolyol Silicone such as ether-modified silicone, polysiloxane-oxyalkylene copolymer, polyglycerin-modified silicone, sugar-modified silicone Nonionic surfactants, etc .; for cationic surfactants, alkyltrimethylammonium chlorides such as behentrimonium chloride, steartrimonium chloride, cetrimonium chloride, lauryltrimonium chloride; alkyls such as stearyltrimonium bromide Trialkylammonium bromide; dialkyldimethylammonium chloride such as distearyldimonium chloride and dicocodimonium chloride; fatty acid amidoamines and salts thereof such as stearamidepropyldimethylamine and stearamideethyldiethylamine; alkyl ether amines such as stearoxypropyldimethylamine; Salt or quaternary salt thereof; ethyl sulfate long chain branched fatty acid (12-31) aminopropylethyldimethylammonium, ethyl lanolin sulfate Fatty acid amide-type quaternary ammonium salts such as aminopropylethyldimethylammonium fatty acid; polyoxyethylene alkylamine and its salts or quaternary salts; alkylamine salts; fatty acid amidoguanidinium salts; alkyl etheraminemonium salts; Benzalkonium salts; benzethonium salts; pyridinium salts such as cetylpyridinium chloride; imidazolinium salts; alkylisoquinolinium salts; dialkyl morpholinium salts; polyamine fatty acid derivatives; Silicone-based cationic surfactants such as amino-modified silicone, cation-modified silicone, cation-modified and polyether-modified silicone, amino-modified and polyether-modified silicone, etc .; amphoteric Surfactants include N-alkyl-N, N-dimethylamino acid betaines such as lauryl betaine (lauryldimethylaminoacetic acid betaine); fatty acid amide alkyl-N, N-dimethylamino acid betaines such as cocamidopropyl betaine and lauramidopropyl betaine. Imidazoline-type betaines such as sodium cocoamphoacetate and sodium lauroamphoacetate; alkylsulfobetaines such as alkyldimethyltaurine; sulfate-type betaines such as alkyldimethylaminoethanol sulfate; phosphate-type betaines such as alkyldimethylaminoethanolphosphate; phosphatidylcholine , Phosphatidylethanolamine, phosphatidylserine, sphingomyelin and other sphingophospholipids, lysolecithin, hydrogenated soybean phospholipid, partially hydrogenated soybean Phospholipids such as phospholipids, hydrogenated egg yolk phospholipids, partially hydrogenated egg yolk phospholipids, and hydroxylated lecithin; silicone-based amphoteric surfactants; polymer surfactants such as polyvinyl alcohol, sodium alginate, starch derivatives, tragacanth gum , Acrylic acid / alkyl methacrylate copolymer, 2-methacryloyloxyethyl phosphorylcholine / stearyl methacrylate copolymer; and various silicone surfactants.

  Polymers, thickeners and gelling agents include guar gum, locust bean gum, queens seed, carrageenan, galactan, arabic gum, tara gum, tamarind, far selelain, karaya gum, troarooi, cara gum, tragacanth gum, pectin, pectic acid and sodium Salt such as salt, salt such as alginic acid and sodium salt, mannan; starch such as rice, corn, potato, wheat; xanthan gum, dextran, succinoglucan, curdlan, hyaluronic acid and its salt, xanthan gum, pullulan, gellan gum, chitin , Chitosan, agar, gypsum extract, chondroitin sulfate, casein, collagen, gelatin, albumin; methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropi Cellulose, carboxymethylcellulose and salts thereof such as sodium, methylhydroxypropylcellulose, cellulose sodium sulfate, cellulose dialkyldimethylammonium sulfate, crystalline cellulose, cellulose such as cellulose powder and derivatives thereof; soluble starch, carboxymethyl starch, methylhydroxypropyl starch, Starch-based polymers such as methyl starch, starch derivatives such as hydroxypropyltrimonium chloride, octenyl succinate corn starch and aluminum; alginic acid derivatives such as sodium alginate, propylene glycol alginate; Vinyl pydridone-vinyl alcohol copolymer, polyvinyl methyl ether Polyethylene glycol, polypropylene glycol, polyoxyethylene / polyoxypropylene copolymer; amphoteric methacrylic acid such as (methacryloyloxyethylcarboxybetaine / alkyl methacrylate) copolymer, (acrylates / stearyl acrylate / ethylamine methacrylate oxide) copolymer, etc. Ester copolymer; (Dimethicone / vinyl dimethicone) crosspolymer, (alkyl acrylate / diacetone acrylamide) copolymer, (alkyl acrylate / diacetone acrylamide) copolymer AMP; Polyvinyl acetate partial saponification product, maleic acid copolymer; Vinylpyrrolidone / dialkylaminoalkyl methacrylate copolymer; acrylic resin alkanolamine; polyester, water-dispersible polyester; Kurylamide; Polyacrylic acid ester copolymer such as polyethyl acrylate, carboxyvinyl polymer, polyacrylic acid and its sodium salt, acrylic acid / methacrylic acid ester copolymer; acrylic acid / alkyl methacrylate Polymer: Cationized cellulose such as polyquaternium-10, diallyldimethylammonium chloride / acrylamide copolymer such as polyquaternium-7, acrylic acid / diallyldimethylammonium chloride copolymer such as polyquaternium-22, and acrylic acid such as polyquaternium-39・ Diallyldimethylammonium chloride / acrylamide copolymer, acrylic acid / cationized methacrylic acid ester copolymer, acrylic acid / cationized methacrylic acid amide copolymer, polyquaternium Acrylic acid / methyl acrylate / methacrylamidopropyltrimethylammonium chloride copolymer such as 47, methacrylic acid choline ester polymer; cationized polysaccharides such as cationized oligosaccharide, cationized dextran, guar hydroxypropyltrimonium chloride; Polyethyleneimine; Cationic polymer; Polymer of 2-methacryloyloxyethyl phosphorylcholine such as polyquaternium-51 and copolymer with butyl methacrylate copolymer; Acrylic resin emulsion, polyethyl acrylate emulsion, polyacrylalkyl ester emulsion, Polymer emulsions such as polyvinyl acetate resin emulsion, natural rubber latex, synthetic latex; nitrocellulose; polyurethanes and various copolymers; various silicones Various silicone-based copolymers such as acrylic-silicone graft copolymers; various fluoropolymers; 12-hydroxystearic acid and its salts; dextrin fatty acid esters such as dextrin palmitate and dextrin myristate; silicic anhydride, Smoke-like silica (ultrafine silicic anhydride), aluminum magnesium silicate, magnesium magnesium silicate, metal soap, dialkyl phosphate metal salt, bentonite, hectorite, organically modified clay mineral, sucrose fatty acid ester, fructooligosaccharide fatty acid ester It is mentioned as preferable.

  Solvents and propellants include ethanol, 2-propanol (isopropyl alcohol), butanol, isobutyl alcohol and other lower alcohols; propylene glycol, 1,3-butylene glycol, diethylene glycol, dipropylene glycol, isopentyl diol and other glycols Diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, triethylene glycol monoethyl ether, diethylene glycol diethyl ether, diethylene glycol dibutyl ether, propylene glycol monoethyl ether, dipropylene glycol monoethyl ether Glycol ethers such as ethylene glycol monoethyl ether Glycol ether esters such as acetate, diethylene glycol monoethyl ether acetate and propylene glycol monoethyl ether acetate; Glycol esters such as diethoxyethyl succinate and ethylene glycol disuccinate; benzyl alcohol, benzyloxyethanol, propylene carbonate, dialkyl carbonate , Acetone, ethyl acetate, N-methylpyrrolidone; toluene; fluorocarbon, next-generation flon; propellants such as LPG, dimethyl ether, carbon dioxide, and the like are preferable.

  Antioxidants include α-lipoic acid, salts of α-lipoic acid, and derivatives of α-lipoic acid; tocopherol derivatives such as tocopherol (vitamin E), tocotrienol, tocopherol acetate; BHT, BHA; propyl gallate, etc. Gallic acid derivatives; vitamin C (ascorbic acid) and / or derivatives thereof; erythorbic acid and derivatives thereof; sulfites such as sodium sulfite; bisulfites such as sodium bisulfite; thiosulfates such as sodium thiosulfate; metabisulfite Salts: thiotaurine, hypotaurine; thioglycerol, thiourea, thioglycolic acid, cysteine hydrochloride are preferred. Preferred examples of the reducing agent include thioglycolic acid, cysteine, cysteamine and the like.

  Preservatives and antibacterial agents include hydroxybenzoic acid such as methylparaben, ethylparaben, propylparaben, and butylparaben and salts or esters thereof; salicylic acid; sodium benzoate; phenoxyethanol; 1,2-pentanediol, 1,2-hexane 1,2-diols such as diols; isothiazolinone derivatives such as methylchloroisothiazolinone and methylisothiazolinone; imidazolinium urea; dehydroacetic acid and its salts; phenols; halogenated bisphenols such as triclosan, acid amides , Quaternary ammonium salts; trichlorocarbanide, zinc pyrithione, benzalkonium chloride, benzethonium chloride, sorbic acid, chlorhexidine, chlorhexidine gluconate, halocarban, hexachlorophene, Kichioru; phenol, isopropyl phenol, cresol, thymol, p-chlorophenol, phenylphenol, other phenols such as phenylphenol sodium; phenylethyl alcohol, photosensitive Motorui, be mentioned as antibacterial zeolite, silver ion.

Examples of chelating agents include edetates (ethylenediaminetetraacetate) such as EDTA, EDTA2Na, EDTA3Na, and EDTA4Na; hydroxyethylethylenediaminetriacetates such as HEDTA3Na; pentetates (diethylenetriaminepentaacetate); phytic acid; Phosphonic acid and its sodium salt; sodium oxalate; polyamino acids such as polyaspartic acid and polyglutamic acid; sodium polyphosphate, sodium metaphosphate, phosphoric acid; sodium citrate, citric acid, alanine, dihydroxyethylglycine Gluconic acid, ascorbic acid, succinic acid, and tartaric acid are preferable.

pH adjusters / acids / alkalis include citric acid, sodium citrate, lactic acid, sodium lactate, glycolic acid, succinic acid, acetic acid, sodium acetate, malic acid, tartaric acid, fumaric acid, phosphoric acid, hydrochloric acid, sulfuric acid, monoethanol Amine, diethanolamine, triethanolamine, isopropanolamine, triisopropanolamine, 2-amino-2-methyl-1,3-propanediol, 2-amino-2-hydroxymethyl-1,3-propanediol, arginine, hydroxylation Sodium, potassium hydroxide, aqueous ammonia, guanidine carbonate, and ammonium carbonate are preferable.

  Examples of powders include mica, talc, kaolin, sericite, montmorillonite, kaolinite, mica, muscovite, phlogopite, synthetic mica, red mica, biotite, permiculite, magnesium carbonate, calcium carbonate, aluminum silicate, silica Barium acid, calcium silicate, magnesium silicate, strontium silicate, metal tungstate, magnesium, zeolite, barium sulfate, calcined calcium sulfate, calcium phosphate, fluorine apatite, hydroxyapatite, ceramic powder, bentonite, smectite, clay, mud, Metal soap (e.g. zinc myristate, calcium palmitate, aluminum stearate), calcium carbonate, bengara, yellow iron oxide, black iron oxide, ultramarine, bitumen, carbon black, titanium oxide, fine particles and ultrafine Titanium oxide, zinc oxide, fine and ultrafine zinc oxide, alumina, silica, fumed silica (ultrafine silica), titanium mica, fish scale foil, boron nitride, photochromic pigment, synthetic fluorophlogopite, fine particle composite powder Body, gold, aluminum, etc., various sizes and shapes of inorganic powders, and these are treated with various surface treatment agents such as hydrogen silicone, cyclic hydrogen silicone, or other silane or titanium coupling agents Inorganic powders such as hydrophobized or hydrophilized powders; starch, cellulose, nylon powder, polyethylene powder, polymethyl methacrylate powder, polystyrene powder, copolymer resin powder of styrene and acrylic acid, polyester powder, Benzoguanamine resin powder, polyethylene terephthalate, polymethyl Organic powders and surface-treated powders of various sizes and shapes, such as methacrylate powder, polyethylene terephthalate / aluminum / epoxy powder, urethane powder, silicone powder, Teflon (registered trademark) powder, organic-inorganic composite powder Is preferable. Inorganic salts include sodium chloride-containing salts such as salt, common salt, rock salt, sea salt, natural salt; potassium chloride, aluminum chloride, calcium chloride, magnesium chloride, bittern, zinc chloride, ammonium chloride; sodium sulfate, aluminum sulfate, Aluminum sulfate / potassium sulfate (alum), aluminum sulfate / ammonium sulfate, barium sulfate, calcium sulfate, potassium sulfate, magnesium sulfate, zinc sulfate, iron sulfate, copper sulfate; sodium phosphates such as 1Na, 2Na and 3Na phosphates, phosphoric acid Potassium, calcium phosphates and magnesium phosphates are preferred.

  Examples of ultraviolet absorbers include paraaminobenzoic acid, paraaminobenzoic acid monoglycerin ester, N, N-dipropoxyparaaminobenzoic acid ethyl ester, N, N-diethoxyparaaminobenzoic acid ethyl ester, and N, N-dimethylparaaminobenzoic acid ethyl ester. Benzoic acid-based ultraviolet absorbers such as esters, N, N-dimethylparaaminobenzoic acid butyl ester, N, N-dimethylparaaminobenzoic acid ethyl ester; Anthranilic acid-based ultraviolet absorbers such as homomenthyl-N-acetylanthranilate; Salicylic acid And salicylic acid-based purple such as sodium salt, amyl salicylate, menthyl salicylate, homomenthyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, p-isopropanol phenyl salicylate Line absorber: Octyl cinnamate, ethyl-4-isopropyl cinnamate, methyl-2,5-diisopropyl cinnamate, ethyl-2,4-diisopropyl cinnamate, methyl-2,4-diisopropyl cinnamate, propyl-p- Methoxycinnamate, isopropyl-p-methoxycinnamate, isoamyl-p-methoxycinnamate, 2-ethylhexyl p-methoxycinnamate (octyl paramethoxycinnamate), 2-ethoxyethyl-p-methoxycinnamate (sinoxate), Cyclohexyl-p-methoxycinnamate, ethyl-α-cyano-β-phenylcinnamate, 2-ethylhexyl α-cyano-β-phenylcinnamate (octocrine), glyceryl mono-2-ethylhexanoyl-diparamethoxy Cinnamic acid-based UV absorbers such as namate, ferulic acid and derivatives thereof; 2,4-dihydroxybenzophenone, 2,2′-dihydroxy-4-methoxybenzophenone, 2,2′-dihydroxy-4,4′-dimethoxybenzophenone, 2,2 ′, 4,4′-tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone (oxybenzone-3), 2-hydroxy-4-methoxy-4′-methylbenzophenone, 2-hydroxy-4-methoxybenzophenone -5-sulfonate, 4-phenylbenzophenone, 2-ethylhexyl-4'-phenyl-benzophenone-2-carboxylate, 2-hydroxy-4-n-octoxybenzophenone, 4-hydroxy-3-carboxybenzophenone, etc. Benzophenone purple 3- (4'-methylbenzylidene) -d, l-camphor, 3-benzylidene-d, l-camphor; 2-phenyl-5-methylbenzoxazole; 2,2'-hydroxy-5 2- (2′-hydroxy-5′-t-octylphenyl) benzotriazole; 2- (2′-hydroxy-5′-methylphenylbenzotriazole; dibenzalazine; dianisoylmethane; 5- (3 , 3-dimethyl-2-norbornylidene) -3-pentan-2-one; dibenzoylmethane derivatives such as 4-t-butylmethoxydibenzoylmethane; octyl triazone; urocanic acid derivatives such as urocanic acid and ethyl urocanate; 2- (2′-hydroxy-5′-methylphenyl) benzotriazole, 1- ( , 4-dimethoxyphenyl) -4,4-dimethyl-1,3-pentanedione, dimethoxybenzylidenedioxoimidazolidinepropionate 2-ethylhexyl, etc., hydantoin derivatives, phenylbenzimidazolazosulfonic acid, terephthalylidene dicamphsulfone Preference is given to acids, drometrizole trisiloxane, methyl anthranilate, rutin and its derivatives, oryzanol and its derivatives.

  As the whitening agent, ascorbic acid fatty acid such as arbutin, α-arbutin, ascorbic acid, ascorbic acid phosphate sodium salt and ascorbic acid phosphate magnesium salt, ascorbic acid tetraisopalmitate, etc. Ascorbic acid alkyl ethers such as esters, ascorbic acid ethyl ether, ascorbic acid glucosides such as ascorbic acid-2-glucoside and fatty acid esters thereof, ascorbic acid sulfates, ascorbic acid derivatives such as tocopheryl ascorbyl phosphate; kojic acid, ellagic acid Acid, tranexamic acid and its derivatives, ferulic acid and its derivatives, placenta extract, glutathione, oryzanol, butylresorcinol, oil-soluble chamomile extract, oil-soluble Nzouekisu, Nishikawa willow extract, be mentioned as saxifrage extract, and the like plant extracts are preferred.

  Vitamins and their derivatives include vitamin A such as retinol, retinol acetate, retinol palmitate; thiamine hydrochloride, thiamine sulfate, riboflavin, riboflavin acetate, pyridoxine hydrochloride, pyridoxine dioctanoate, pyridoxine dipalmitate, Flavin adenine dinucleotide, cyanocobalamin, folic acid, nicotinic acid such as nicotinic acid amide / benzyl nicotinate, vitamin B group such as choline; vitamin C such as ascorbic acid and its sodium salt; vitamin D; α, Vitamin Es such as β, γ, δ-tocopherol; other vitamins such as pantothenic acid and biotin; ascorbic acid phosphates such as ascorbic acid phosphate sodium salt and ascorbic acid phosphate magnesium salt; Ascorbic acid fatty acid esters such as corobic acid tetraisopalmitic acid ester, ascorbyl stearate, ascorbyl palmitate and ascorbyl dipalmitate, ascorbic acid alkyl ether such as ascorbic acid ethyl ether, ascorbic acid glucoside such as ascorbic acid-2-glucoside and Ascorbic acid derivatives such as fatty acid esters and tocopheryl phosphate ascorbyl; vitamin derivatives such as tocopherol nicotinate, tocopherol acetate, tocopherol acetate, tocopherol linoleate, tocopherol phosphate, tocopherol phosphate etc., tocotrienol, and other various vitamin derivatives Is preferable.

  Anti-inflammatory agents and anti-inflammatory agents include glycyrrhizic acid and its derivatives, glycyrrhetinic acid derivatives, salicylic acid derivatives, hinokitiol, guaiazulene, allantoin, indomethacin, zinc oxide, hydrocortisone acetate, acidic xylooligosaccharides, prednisone, diphedramine hydrochloride, chlorphenic acid maleate. Lamin; plant extracts such as peach leaf extract and persimmon leaf extract are preferred.

Plant growth and tinctures such as assembly extract, red pepper tincture, ginger tincture, ginger extract, cantalis tincture; capsaicin, nonyl acid valenylamide, gingeron, ictamol, tannic acid Borneol, cyclandelate, cinnarizine, trazoline, acetylcholine, verapamil, cephalanthin, γ-oryzanol, cephalanthin, vitamin E and nicotinic acid tocopherol, acetic acid tocopherol and other derivatives, γ-oryzanol, nicotinic acid, nicotinic acid amide, nicotinic acid benzyl Derivatives such as ester, inositol hexanicotinate, nicotine alcohol, allantoin, photosensitizer 301, photosensitizer 401, capronium chloride, pentadecanoic acid monoglyceride, Preferable examples include flavonol derivatives, stigmasterol or stigmasteranol, its glycosides, and minoxidil.

Preferred hormones include estradiol, estrone, ethinyl estradiol, cortisone, hydrocortisone, prednisone and the like.

Other remedies such as anti-wrinkle agents, anti-aging agents, squeeze agents, cooling sensations, warming sensation agents, wound healing promoters, irritation relievers, analgesics, cell activators include retinols, retinoic acids, retinoin Acid tocopheryl; derivatives such as lactic acid, glycolic acid, gluconic acid, fruit acid, salicylic acid and glycosides / esterified products thereof, α- or such as hydroxycapric acid, long chain α-hydroxy fatty acid, long chain α-hydroxy fatty acid cholesteryl β-hydroxy acids and derivatives thereof; γ-aminobutyric acid, γ-amino-β-hydroxybutyric acid; carnitine; carnosine; creatine; ceramides, sphingosines; caffeine, xanthine and the like; and coenzyme Q10, carotene, lycopene , Astaxanthin, lutein and other antioxidant and active oxygen scavengers; catechins; quercet Isoflavones; gallic acid and ester sugar derivatives; polyphenols such as tannin, sesamin, protoanthocyanidin, chlorogenic acid, apple polyphenol; derivatives such as rutin and glycosides; derivatives such as hesperidin and glycosides Lignan glycosides; licorice extract-related substances such as grabridine, glabrene, liquiritin, and isoliquiritin; lactoferrin; gingerol; fragrance substances such as menthol, camphor, cedrol, and derivatives thereof; capsaicin, vanillin, and derivatives; diethyltoluamide Preferable examples include insect repellents such as: complexes of physiologically active substances and cyclodextrins, and nanocolloids such as platinum.

  As plant / animal / microbe extracts, Iris extract, Ashitaba extract, Asunaro extract, Asparagus extract, Avocado extract, Achacha extract, Almond extract, Altea extract, Arnica extract, Aloe extract, Apricot extract, Ginkgo biloba extract, Ginkgo biloba extract , Incheon extract, Fennel extract, Turmeric extract, Oolong tea extract, Peony extract, Ages extract, Echinacea leaf extract, Enmeo extract, Ogon extract, Oat extract, Auren extract, Barley extract, Panax ginseng extract, Hypericum extract, Odori extract , Dutch mustard extract, orange extract, dried sea water, seaweed extract, oyster leaf extract, oyster extract, hydrolyzed elastin, hydrolyzed wheat powder, hydrolysis Luc, Cascon extract, Chamomile extract, Oil-soluble chamomile extract, Carrot extract, Kawara mugi extract, Oat extract, Calcade extract, Licorice extract, Oil-soluble Licorice extract, Kiwi extract, Kiou extract, Cyprid extract, Quina extract, Cucumber extract, Kiri leaf extract, Guanosine, guava extract, cucumber extract, gardenia extract, kumazasa extract, clara extract, walnut extract, chestnut extract, grapefruit extract, clematis extract, black rice extract, brown sugar extract, black vinegar, chlorella extract, mulberry extract, gentian extract, Gentian pepper extract, tea Extract, yeast extract, kokuboku extract, coffee extract, burdock extract, rice extract, rice fermented extract, rice bran fermented extract, rice germ oil, comfrey extract, Lagen, Cowberry extract, Saishin extract, Psycho extract, Saitai extract, Saffron extract, Salvia extract, Salmon extract, Sasa extract, Hawthorn extract, Sansha extract, Salamander extract, Shiitake extract, Giant extract, Shikon extract, Perilla extract, Linden extract, Shimosukeso Extract, jatoba extract, peonies extract, ginger cucumber extract, ginger root extract, white birch extract, white jellyfish extract, horsetail extract, stevia extract, stevia fermented product, west river willow extract, horse chestnut extract, hawthorn extract, elderberry extract, yarrow extract , Mint extract, sage extract, mallow extract, nematode extract, essence extract, Sakuhakuhi extract, Diou extract, Dai Extract, peanut extract, thyme extract, dandelion extract, lichen extract, tea extract, clove extract, chigaya extract, chimpi extract, tea tree oil, tea tea extract, red pepper extract, red snapper extract, red snapper extract, red spruce extract, red spruce extract, tomato Extract, natto extract, carrot extract, garlic extract, wild rose extract, hibiscus extract, bacmond extract, lotus extract, parsley extract, birch extract, honey, hamamelis extract, parietalia extract, hyacinth extract, bisabolol, cypress extract, bifidobacteria extract, Loquat extract, dandelion extract, burdock extract, bukkuri extract, butcher bloom extract, grape extract, grape seed extract, propolis, loofah extract, Safflower extract, peppermint extract, body extract, button extract, hop extract, squid extract, pine extract, maroonnier extract, mizubasho extract, mukuroji extract, melissa extract, mozuku extract, peach extract, cornflower extract, eucalyptus extract, yukinoshita extract, yuzu extract, lily extract, Yokuinin extract, mugwort extract, lavender extract, green tea extract, eggshell membrane extract, apple extract, rooibos tea extract, litchi extract, lettuce extract, lemon extract, forsythia extract, forsythia extract, rose extract, rosemary extract, roman chamomile extract, royal jelly Extracts such as an extract and a bitumen extract are preferred.

  Examples of the antipruritic agent include diphenhydramine hydrochloride, chlorpheniramine maleate, camphor, substance-P inhibitor, and the like. Examples of the exfoliating / dissolving agent include salicylic acid, sulfur, resorcin, selenium sulfide, pyridoxine and the like. Examples of the antiperspirant include chlorohydroxyaluminum, aluminum chloride, zinc oxide, and zinc paraphenol sulfonate. Examples of the refreshing agent include menthol and methyl salicylate. Examples of the astringent include citric acid, tartaric acid, lactic acid, aluminum sulfate / potassium sulfate, and tannic acid. Examples of enzymes include superoxide dismutase, catalase, lysozyme chloride, lipase, papain, pancreatin, protease, and the like. Preferred nucleic acids include ribonucleic acid and salts thereof, deoxyribonucleic acid and salts thereof, and adenosine triphosphate disodium.

  As perfumes, acetyl cedrene, amylcinnamaldehyde, allyl amyl glycolate, β-ionone, iso-Esuper, isobutyl quinoline, Iris oil, Iron, indole, ylang ylang oil, undecanal, undecenal, γ-undecalactone, Estragole, eugenol, oak moss, opoponax resinoid, orange oil, eugenol, auranthiol, galac solid, carvacrol, L-carvone, camphor, cannon, carrot seed oil, clove oil, methyl cinnamate, geraniol, geranyl nitrile , Isobornyl acetate, geranyl acetate, dimethylbenzyl carvinyl acetate, styrylyl acetate, cedolyl acetate, terpinel acetate, pt-butylcyclohexyl acetate, vetiberyl acetate, benzyl acetate, vinegar Linalyl, isopentyl salicylate, benzyl salicylate, sandalwood oil, santalol, cyclamenaldehyde, cyclopentadecanolide, methyl dihydrojasmonate, dihydromilsenol, jasmine absolute, jasmine lactone, cis-jasmon, citral, citronenol, citronellal, Cinnamon bark oil, 1,8-cineole, cinnamaldehyde, stylax resinoid, cedarwood oil, cedrene, cedrol, celery seed oil, thyme oil, damascon, damassenone, thymol, tuberose absolute, decanal, decalactone, terpineol, γ-terpinene, Tripral, Nellore, Nonanal, 2,6-Nonadienol, Nonalactone, Patchouli alcohol, Vanilla absolute, Vanillin Basil oil, patchouli oil, hydroxycitronellal, α-pinene, piperitone, phenethyl alcohol, phenylacetaldehyde, petitglen oil, hexylcinnamaldehyde, cis-3-hexenol, perubalsum, vetiver oil, vetiverol, peppermint oil, pepper oil, Heliotropin, bergamot oil, benzylbenzoate, borneol, milresinoid, musk ketone, methylnonylacetaldehyde, γ-methylyonone, menthol, L-menthol, L-menton, eucalyptus oil, β-yonone, lime oil, lavender oil, D-limonene Synthetic and natural fragrances such as linalool, rillar, rigliall, lemon oil, rose absolute, rose oxide, rose oil, rosemary oil, various essential oils, and various blended fragrances are preferred. It is cited as the.

As pigments / colorants / dyes / pigments, brown 201, black 401, purple 201, purple 401, blue 1, blue 2, blue 201, blue 202, blue 203, blue 204 , Blue 205, Blue 403, Blue 404, Green 201, Green 202, Green 204, Green 205, Green 3, Green 401, Green 402, Red 102, Red 104-1 , Red 105-1, Red 106, Red 2, Red 201, Red 202, Red 203, Red 204, Red 205, Red 206, Red 207, Red 208, Red 213 Red 214, Red 215, Red 218, Red 219, Red 220, Red 221, Red 223, Red 225, Red 226, Red 227, Red 228, Red 230 No. 1, Red 230-2, Red 231, Red 232, Red 3, Red 401, Red 404, Red 405, Red 501, Red 502, Red 503, Red 504, Red 505, red 506, orange 201, orange 203, orange 204, orange 205, orange 206, orange 207, orange 401, orange 402, orange 403, yellow 201, yellow 202- No. 1, yellow 202-2, yellow 203, yellow 204, yellow 205, yellow 4, yellow 401, yellow 402, yellow 403-1, yellow 404, yellow 405, yellow 406 Legal dyes such as Yellow No. 407 and Yellow No. 5; Other acidic dyes such as Acid Red 14; Arianor Sienna Brown, Arianor Madder Red, Arianor
Basic dyes such as Steel Blue and Arianor Straw Yellow; HC Yellow 2, HC Yellow 5, HC Red 3, 4-hydoxypropylamino-3-nitrophenol, N, N'-bis (2-hydroxyethyl) -2-nitro-p-
Nitro dyes such as phenylenediamine, HC Blue 2 and Basic Blue 26; disperse dyes; inorganic white pigments such as titanium dioxide and zinc oxide; inorganic red pigments such as iron oxide (Bengara) and iron titanate; and γ-iron oxide Inorganic brown pigments; inorganic yellow pigments such as yellow iron oxide and ocher; inorganic black pigments such as black iron oxide and low-order titanium oxide; inorganic purple pigments such as mango violet and cobalt violet; chromium oxide and chromium hydroxide Inorganic green pigments such as cobalt titanate; inorganic blue pigments such as ultramarine and bitumen; titanium oxide coated mica, titanium oxide coated bismuth oxychloride, titanium oxide coated talc, colored titanium oxide coated mica, bismuth oxychloride, fish scale foil Pearl powder such as aluminum powder, copper powder, metal powder pigment such as gold; surface treatment inorganic and metal powder pigment; red 01, Red 202, Red 204, Red 205, Red 220, Red 226, Red 228, Red 405, Orange 203, Orange 204, Yellow 205, Yellow 401, Blue 404 Red No. 3, Red No. 104, Red No. 106, Red No. 227, Red No. 230, Red No. 401, Red No. 505, Orange No. 205, Yellow No. 4, Yellow No. 5, Yellow No. 202, Yellow No. 203, Green Organic pigments such as zirconium, barium or aluminum lakes such as No. 3 and Blue No. 1; surface-treated organic pigments; anthraquinones such as astaxanthin and alizarin, anthocyanidins, β-carotene, catenal, capsanthin, chalcone, calsamine, quercetin, crocin, Naphthoquinones such as chlorophyll, curcumin, cochineal, shikonin, bixin, flavo Natural pigments and dyes such as amines, betacyanidine, henna, hemoglobin, lycopene, riboflavin, rutin; p-phenylenediamine, toluene-2,5-diamine, o-, m-, or p-aminophenol, m-phenylene Oxidative dye intermediates and couplers such as diamine, 5-amino-2-methylphenol, resorcin, 1-naphthol, 2,6-diaminopyridine and their salts; auto-oxidizing dyes such as indoline; Can be mentioned.

  In addition to these, cosmetic raw material standards, blending ingredient standard by cosmetic varieties, Japan Cosmetic Industry Association ingredient display name list, INCI dictionary (The International Cosmetic Ingredient Dictionary and Handbook), quasi-drug raw material standards, Japanese pharmacopoeia, pharmaceutical additives Ingredients listed in standards, official food additives, etc., and Japanese and foreign patent publications and patent publications (including publications and republications) in which the international patent classification IPC belongs to the classification of A61K7 and A61K8 It is possible to contain known cosmetic ingredients, pharmaceutical ingredients, food ingredients, etc., such as the ingredients described, in known combinations, blending ratios and blending amounts.

  As the types of cosmetics and skin external preparations of the present invention, skin external preparations such as basic cosmetics, hair cosmetics, makeup cosmetics, aromatic cosmetics, body cosmetics, ointments and the like can be mentioned as preferable ones. Basic cosmetics are preferred. The cosmetic / skin external preparation of the present invention can be produced according to a usual method.

  The types of cosmetics and skin external preparations according to the present invention will be described in more detail. Examples of basic cosmetics include whitening lotions, whitening serums, moisturizing essences, UV prevention essences; emollient lotions, moisturizing lotions, milky lotions. , Nourishing Lotion, Nourishing Milk, Skin Moisture, Moisturizer Emulsion, Massage Lotion, Cleansing Lotion, Protect Emulsion, Sun Protect, Sun Protector, UV Care Milk, Sun Screen, Makeup Lotion, Horny Smoother, Elbow Lotion, Hand Lotion , Body lotion and other emulsions; soft lotion, astringent lotion, cleansing lotion, multi-layer lotion, etc .; liposome beauty lotion, liposome lotion; emollient cream Nutrition cream, Nourishing cream, Vanishing cream, Moisture cream, Night cream, Massage cream, Cleansing cream, Makeup cream, Base cream, Pre-makeup cream, Sunscreen cream, Suntan cream, Hair removal cream, Deodorant cream, Shaving cream, Horny cream Creams such as softening creams; cleansing foams, cleansing powders, facial cleansing powders, cleansing creams, cleansing milks, cleansing lotions, cleansing gels, cleansing oils, cleansing masks, etc. gels such as cleansing gels, moisturizing gels, cosmetic soaps, transparent soaps , Medicated soap, liquid soap, shaving soap, synthetic soap, etc .; peel-off pack, powder pack, u Tsu single pack, oil pack, pack mask such as cleansing mask can be mentioned as preferred.

  Cosmetics for hair include oil shampoo, cream shampoo, conditioning shampoo, dandruff shampoo, hair color shampoo, shampoo with integrated rinse, shampoo, rinse, treatment, hair pack, hair foam, hair mousse, hair spray, hair mist, Hair wax, hair gel, water grease, set lotion, color lotion, hair tonic, hair liquid, pomade, tic, hair cream, hair blow, split hair coat, hair oil, permanent wave agent, straight permanent agent, oxidative hair dye, hair Bleach, hair color pre-treatment, hair color after-treatment, perm pre-treatment, perm-after treatment, hair nail polish, hair restorer are preferred And the like Te.

  Examples of makeup cosmetics that may be preferably used include white powder, dusts, foundations, lipsticks, lip gloss, blushers, eyeliner, mascara, eye shadow, eyebrow, eyebrow, nail enamel, enamel remover, and nail treatment.

  Preferred examples of the aromatic cosmetics include perfume, perfume, parfum, eau de parfum, eau de toilette, eau de cologne, perfumes, fragrance powder, perfume soap, body lotion and bath oil.

  Body cosmetics such as body shampoos; deodorant lotions, deodorant powders, deodorant sprays, deodorant sticks and other deodorant cosmetics; decoloring agents, hair removal / hair removal agents; bathing agents; insect repellents A repeller is preferred.

  Moreover, as a skin external preparation, it can be used also as dosage forms, such as an ointment, a patch, a lotion, a liniment, and a liquid coating agent. It can also be used as an oral cosmetic such as toothpaste and mouthwash.

  As the dosage form of the cosmetic or external preparation for skin of the present invention, liquid cosmetic, oil-in-water (O / W) type, water-in-oil (W / O) type, W / O / W type, O / W / O Emulsified cosmetics such as molds, jelly cosmetics, gel cosmetics, paste cosmetics, sheet cosmetics, mist cosmetics, spray cosmetics, kneaded cosmetics, stick cosmetics, etc. A mold is preferable.

  EXAMPLES Hereinafter, although this invention is demonstrated in detail using an Example, this invention is not limited to these Examples. The amount of the component to be blended is weight% unless otherwise specified. The weight average molecular weight described below is a value measured by a gel permeation chromatography (GPC) method using polyethylene oxide having a known molecular weight as a standard substance in an aqueous solvent (measuring instrument; Tosoh Corporation) GPC-8020, column; TSK-GEL α-3000, α-6000).

Example 1 Production Example 50 g of a dried product of commercially available white jellyfish fruit bodies was pulverized, extracted with 2 L of hot water, filtered, and the filtrate was dried to obtain 5 g of a dry powder. 75 g of 7.5M HCl was added to 75 g of the 1% aqueous solution and reacted at 65 ° C. to 70 ° C. for 16 hours. This was neutralized with NaOH to obtain 187.5 g of a hydrolyzed solution. As a result of GPC measurement, the weight average molecular weight was about 12,000.

Example 2 Production Example 50 g of 7.5 M HCl was added to 50 g of a 1% aqueous solution of a water-soluble polysaccharide (manufactured by Nippon Seika Co., Ltd., trade name: Tremoist-TP) extracted from commercially available white jellyfish fruit bodies, and the temperature was 65 ° C. to 70 ° C. The reaction was carried out at 20 ° C. for 20 hours. This was neutralized with Mg (OH) ₂ to obtain 125 g of a hydrolyzed solution. As a result of measuring GPC, the weight average molecular weight was about 12,000.

Example 3 Production Example 75 g of 7.5M HCl was added to 75 g of a 1% aqueous solution of a water-soluble polysaccharide (manufactured by Nippon Seika Co., Ltd., trade name: Tremoiist-TP) extracted from a commercially available white jellyfish fruit body, and 65 ° C. to 70 ° C. The reaction was carried out at 24 ° C. for 24 hours. This was neutralized with NaOH to obtain 188.5 g of a hydrolyzed solution. As a result of measuring GPC, the weight average molecular weight was about 11,000.

Example 4 Production Example HCl was added to 50 g of a 2% aqueous solution of a water-soluble polysaccharide (manufactured by Nippon Seika Co., Ltd., trade name: Tremoist-TP) extracted from commercially available white jellyfish fruit bodies, and 75- The reaction was performed at 80 ° C. for 16 hours. This was neutralized with KOH to obtain 250 g of a hydrolyzed solution. As a result of measuring GPC, the weight average molecular weight was about 9000.

Example 5 Evaluation of Antioxidant Action (SOD-like Activity) SOD (superoxide dismutase) is an in vivo antioxidant enzyme that works to eliminate superoxide, but has the same action as this enzyme that other substances have. This is called SOD-like activity. The SOD-like activity is measured by the superoxide erasure rate. The higher the value, the higher the SOD-like activity. Table 1 shows the results of measuring the SOD-like activity of the hydrolysates prepared in Examples 1 to 4.

(Measurement method) 3.0 mol / L xanthine (dissolved in 0.05 mol / L sodium carbonate buffer) 0.1 mL, 3.0 mmol / L in 2.2 mL of 0.05 mol / L sodium carbonate buffer (pH 10.2) EDTA 0.1 mL, 0.15% (w / v) bovine serum albumin 0.1 mL, 0.75 mmol / L nitroblue tetrazolium 0.1 mL and each test sample 0.3 mL were mixed and allowed to stand at room temperature for 10 minutes. Next, 0.1 mL of a xanthine oxidase solution (diluted to about 0.04 units / mL with purified water) was added to start the reaction. After incubation at room temperature for 20 minutes, 0.1 mL of 6 mmol / L cupric chloride was added. To stop the reaction. Next, the absorbance (A) at 560 nm was measured.

Absorbance (B) of the sample to which purified water was added instead of the test sample for the control, and 0.1 mL of xanthine oxidase after the reaction was stopped by adding 0.1 mL of 6 mmol / L cupric chloride to the blank of each sample The absorbance (C) of the sample to which was added was measured. From the following formula 1, the superoxide inhibition rate (%) was calculated. The test was conducted at a solid content (evaporation residue) concentration of 0.05% by weight. (Expression 1) Superoxide inhibition rate (%) = {1− (A−C) / B} × 100

From the results in Table 1, it was confirmed that the SOD-like activity of the present hydrolyzate was greatly improved as compared with that before hydrolysis. From this, it was found that the hydrolyzate has excellent antioxidant activity.

Example 6 Evaluation of Antioxidation Effect (DPPH Radical Scavenging Test) DPPH (α, α-diphenyl-β-picrylhydradil) is a compound having a maximum absorption of 517 nm in a radical state. The DPPH inhibition rate is a rate of decrease in absorbance at 517 nm of DPPH when an antioxidant is added to DPPH for reduction, and the antioxidant ability of the antioxidant can be evaluated based on this value. The greater the DPPH inhibition rate, the higher the antioxidant ability.

Table 2 shows the results of measuring the DPPH inhibition rate for the hydrolysates prepared in Examples 1 to 4 above.

(Measurement method) 0.5 mmol / L DPPH / ethanol solution 0.5 mL, ethanol 0.5 mL, 0.05 mol / L Tris-HCl (pH 7.4) 1.25 mL, 0.25 mL of sample was added, and 517 nm after 10 minutes. The absorbance was measured with (B). As a control, the same operation was performed using a solvent in which the sample solution was dissolved instead of the sample solution, and the absorbance at 517 nm was measured (A). Moreover, the absorbance (C) of each sample solution was measured as a blank, and the radical elimination rate (%) was calculated from the following formula 2. The test was conducted at a solid content (evaporation residue) concentration of 0.3% by weight. (Equation 2) DPPH radical elimination rate (%) = {1− (B−C) / A} × 100

From the results of Table 2, it was confirmed that the hydrolyzate has radical scavenging activity for DPPH and is improved as compared with that before hydrolysis.

Example 7 A moisturizing lotion having the following formulation was prepared using the hydrolyzed liquid obtained in Examples 1 to 4.
Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4
10.00
2 BG
1.00
3 Glycerin
2.00
4 Citric acid 0.01
5 Na citrate 0.10
6
Arginine 0.10
7 Glycyrrhizic acid 2K 0.05
8 Ethanol 7.00
9 Preservative appropriate amount
Ten
Perfume
11 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1-6 are No. 11 and stirred and mixed uniformly (part A). Next, no. 9 to 10 are No. No. 8 after dissolution in No. 8 7 was added and dispersed (part B). A part was added to part B with stirring to make it uniform.

Example 8 Moisturizing lotion With the hydrolyzate obtained in Examples 1 to 4, a moisturizing lotion having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4
10.00
2 BG
1.00
3 Diglycerin 2.00
4 Citric acid 0.01
5 Na citrate 0.05
6
Glycine 0.10
7 Glycyrrhizic acid 2K 0.05
8 Ethanol 3.00
9 Preservative appropriate amount
Ten
Perfume
11
Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1-6 are No. 11 and stirred and mixed uniformly (part A). Next, no. 9 to 10 are No. No. 8 after dissolution in No. 8 7 was added and dispersed (part B). A part was added to part B with stirring to make it uniform.

Example 9 Tightening lotion (astringent lotion)
Using the hydrolyzed liquid obtained in Examples 1 to 4, squeeze lotion having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4
10.00
2 BG
2.00
3 Glycerin
0.04
4 Lactic acid 0.10
5 Lactic acid Na 0.05
6
Zinc phenol sulfonate 0.10
7 PEG-60 hydrogenated castor oil 0.50
8 Ethanol
15.00
9 Preservative appropriate amount
Ten
Perfume
11
Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1-7 are No. 11 and stirred and mixed uniformly (part A). Next, no. 9 to 10 are No. 8 (part B). A part was added to part B with stirring to make it uniform.

Example 10 Cosmetic liquid The cosmetic liquid of the following prescription was prepared using the hydrolyzed liquid obtained in Examples 1-4.

Component Blending amount (% by weight)
----------------------------------
Part A Examples 1 to 4 hydrolyzate
10.00
Preservative appropriate amount PEG-40 hydrogenated castor oil 0.20
Purified water 5.00
Part B xanthan gum 0.40
Carbomer 0.10
BG
10.00
White jellyfish polysaccharide (Nippon Seika) 0.10
Purified water Amount to be 100 in total C part Hydroxide K (1% aqueous solution) 2.50
Purified water 10.00
Part D glycyrrhizic acid 2K 0.20
Purified water 10.00
----------------------------------
(Production method)
Part A was dissolved at room temperature. Part C was gradually added to B part while stirring to obtain a viscous liquid, and then part A and part D were added and stirred to make uniform.

Example 11 Emollient Cream An emollient cream having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4
10.00
2 Hydrogenated palm oil 2.50
3 Behenyl alcohol 2.00
4 Dimethicone (10cs) 1.50
5 Glyceryl stearate 1.50
6 Stearyl alcohol 1.20
7 Stearic acid PG (SE)
1.00
8 PEG-60 glyceryl isostearate 1.00
9 Octyl methoxycinnamate 0.20
Ten
Ethylparaben 0.10
11
1,3-butylene glycol 6.00
12
Glycerin 1.00
13
Phenoxyethanol 0.20
14
Methylparaben 0.15
15
Purified water 75.65
--------------------------------
(Preparation method)
No. 1-10 were added, and it heated and melt | dissolved at about 80 degreeC (A part). No. in a separate container. 11 to 15 were taken, heated to about 80 ° C., and dissolved uniformly (part B). Part B was added to part A, emulsified with a homomixer, and then cooled to 40 ° C.

Example 12 Base Cream Using the hydrolyzate obtained in Examples 1 to 4, a base cream having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4
2 Cyclomethicone
15.00
3 Trimethylsiloxysilicate 3.00
4 Glyceryl stearate (SE) 2.00
5 PG stearate (SE) 2.00
6 Macadamia nut fatty acid phytosteryl 2.00
7 Stearic acid 0.50
8 Palmitic acid 0.50
9 Octyl methoxycinnamate 0.50
Ten
Tocopherol 0.20
11
1,3-butylene glycol 10.00
12
Mica 8.00
13
Talc 7.00
14
Phenoxyethanol 0.80
15
Titanate (Li / Cobalt) 0.20
16
Xanthan gum (10%) 2.00
17
Cellulose gum (10%) 2.00
18
Purified water 39.30
--------------------------------
(Preparation method)
No. 16 and 17 are No. It was dissolved in 18 to give a viscous liquid (2%) (part A). No. in a separate container. 1-10 was added, and it heated and dissolved at about 80 degreeC (B part). No. in a separate container. 11-15, no. The remainder of 18 was added and heated to about 80 ° C. and dissolved (part C). After adding part C to part B and emulsifying, part A was added and mixed uniformly. It cooled to 40 degreeC after stirring.

Example 13 Emollient cream An emollient cream having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4 1.20
2 Cetyl octanoate
6.60
3 Hydrogenated palm oil 4.20
4 Glyceryl stearate (SE) 2.20
5 PEG-60 glyceryl isostearate 1.90
6 Stearic acid PG (SE) 0.60
7 Stearyl alcohol 0.60
8 Dimethicone (10cs) 1.80
9 Ethylparaben 0.10
Ten
1,3-butylene glycol 3.00
11
Glycerin 1.00
12
Phenoxyethanol 0.20
13
Methylparaben 0.15
14
Purified water 76.45
--------------------------------
(Preparation method)
No. 1 to 9 were heated to about 70 ° C. and dissolved uniformly (part A). Next, no. 10-14 were heated to about 70 ° C. and dissolved uniformly (part B). To Part A, Part B was added with stirring and emulsified, and then cooled.

Example 14 Emollient cream An emollient cream having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4
10.00
2 Cetyl octanoate
5.00
3 PEG-60 glyceryl isostearate 1.50
4 Hydrogenated palm oil
14.00
5 Ethylparaben 0.20
6 Stearyl alcohol 3.50
7 Glyceryl stearate (SE) 1.00
8 Steerless-6 1.50
9 PEG-8 distearate 1.00
Ten
Cetanol 3.00
11
Cetyl palmitate 2.00
12
Isocetyl myristate 5.00
13
Cetyl dimethicone copolyol 0.50
14
Tocopherol 0.20
15
Dimethicone (10cs) 1.00
16
Glycerin 4.00
17
Methylparaben 0.20
18
1,3-butylene glycol 6.00
19
Purified water 40.40
--------------------------------
(Preparation method)
No. 1 to 15 were heated to about 70 ° C. and dissolved uniformly (part A). Next, no. 16 to 19 were heated to about 70 ° C. and dissolved uniformly (part B). To Part A, Part B was added with stirring and emulsified, and then cooled.

Example 15 Massage Cream Using the hydrolyzed liquid obtained in Examples 1 to 4, massage creams having the following prescription were prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4 4.00
2 Macadamia nut fatty acid phytosteryl 8.00
3 Glyceryl stearate (SE) 2.00
4 Polysorbate 60 1.80
5 Sorbitan stearate 1.00
6 Polyglyceryl stearate-10 0.50
7 Cholesterol 0.20
8 Dimethicone (10cs) 1.00
9 Myristyl alcohol 1.00
Ten
Stearic acid 1.00
11
Stearyl alcohol 0.50
12
Behenyl alcohol 0.50
13
Hydrogenated palm oil 9.00
14
Tocopherol 0.10
15
Isostearyl palmitate 2.00
16
Cetyl octanoate 15.00
17
Ethylparaben 0.20
18
Phenoxyethanol 0.20
19
Methylparaben 0.10
20
1,3-butylene glycol 10.00
twenty one
Glycerin 3.00
twenty two
Purified water 38.90
--------------------------------
(Preparation method)
No. 1 to 17 were heated to about 70 ° C. and dissolved uniformly (part A). Next, no. 18-22 was heated to about 70 ° C. and dissolved uniformly (part B). To Part A, Part B was added with stirring and emulsified, and then cooled.

Example 16 Emulsion An emulsion having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4
2 Sorbitan stearate 0.50
3 PEG-10 stearate 0.50
4 Polysorbate 60 0.50
5 Cetyl octanoate 3.70
6 Cetanol 1.20
7 Dimethicone (10cs) 1.00
8 Ethylparaben 0.10
9 1,3-butylene glycol 3.00
Ten
Glycerin 1.00
11
Phenoxyethanol 0.20
12
Methylparaben 0.15
13
Citric acid 0.01
14
Na citrate 0.09
15
Xanthan gum 0.10
16
Carbomer 0.15
17
Hydroxide K 0.06
18
Purified water 82.74
--------------------------------
(Preparation method)
No. 15 for some No. 15 18 and stirred to give a viscous liquid (Part A). No. 16 is a part of No.16. No. 18 after stirring, 17 was added to obtain a viscous liquid (Part B). Next, no. 1 to 8 were heated to about 70 ° C. and dissolved (part C). No. 9-14, the remaining No. 18 was heated to about 70 ° C. and dissolved (part D). Part D was added to part C with stirring and emulsified, then cooled to about 50 ° C., part A and part B were added and stirred until uniform.

Example 17 Anti-aging cream The anti-aging cream of the following prescription was prepared using the hydrolysis liquid obtained in Examples 1-4.

Component Blending amount (% by weight)
----------------------------------
A
Cetyl octanoate 7.00
Batyl isostearate 2.00
PEG-60 glyceryl isostearate 1.50
Hydrogenated palm oil 3.70
Ceramide 2 0.10
Retinol 0.10
Oil-soluble chamomile extract 0.10
Ethylparaben 0.20
Stearyl alcohol 3.50
Glyceryl stearate (SE) 1.00
Steerless-6 1.50
Distearic acid PEG-8 1.00
Cetanol 1.00
Dimethicone 1.00
Cetyl dimethicone copolyol 0.50
Tocopherol 0.20
B
Nishi Healing Extract 0.05
C
Hydrolysis solutions of Examples 1-4
15.00
Arbutin 0.50
Ascorbic acid 2-O-glucoside 0.50
EDTA-3Na 0.10
Polyglutamic acid (Ichimaru Falcos, Bio PGA solution) 0.10
Glycerin 4.00
Bisulfite Na 0.05
Methylparaben 0.10
Phenoxyethanol 0.10
BG 6.00
Hydroxide K Appropriate amount of purified water Total amount of 100 ----------------------------------
(Production method)
A was heated to about 80 ° C. and dissolved uniformly (part A). C was heated to about 80 ° C. and dissolved (part C). While stirring with a homomixer at about 80 ° C., part C was gradually added to part A, mixed uniformly after emulsification, cooled to about 40 ° C., B was added and mixed uniformly.

Example 18 Moisturizing lotion With the hydrolyzed liquid obtained in Examples 1 to 4, a moisturizing lotion having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4 2.00
2 BG
1.00
3 Glycerin
2.00
4 Citric acid 0.01
5 Na citrate 0.10
6
Ubiquinone 0.03
7 IOTG (Japan Seika) 0.03
8 Solves-60 tetraoleate 0.12
9 PEG-60 hydrogenated castor oil 0.03
Ten
PEG-30 glyceryl isostearate 0.03
11
Methylparaben 0.20
12
Perfume
13
Ethanol 7.00
14 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1-5 are No. 14 and stirred and mixed uniformly (part A). Next, no. 6-12 are No. 13 (part B). A part was added to part B with stirring to make it uniform.

Example 19 Shampoo Using the hydrolyzate obtained in Examples 1 to 4, shampoos having the following formulation were prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1 to 4 3.00
2 Naureus sulfate (27%)
30.00
3 Lauroamphoacetate Na (25%)
10.00
4 PPG-2 Cocamide 1.50
5 Lauramide MPA 1.00
6
Polyquaternium-10 0.20
7 Methylisothiazolinone 0.01
8
Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 5 were heated to about 80 ° C. and dissolved uniformly (part A). Next, no. 6-8 were heated to about 80 ° C. and dissolved uniformly (part B). Part B was added to part A and mixed with stirring at about 80 ° C. until uniform, and then cooled.

Example 20 Shampoo Using the hydrolyzate obtained in Examples 1 to 4, a shampoo having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1 to 4 3.00
2 Cocamidopropyl betaine (40%)
40.00
3 Cocoa glutamate TEA (27%)
10.00
4 Tetradecenesulfonic acid Na (36%) 2.00
5 PEG120-Methylglucose dioleate 3.00
6 Triethanolamine 0.20
7 Methylisothiazolinone 0.01
8
Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 5 were heated to about 80 ° C. and dissolved uniformly (part A). Next, no. 6-8 were heated to about 80 ° C. and dissolved uniformly (part B). Part B was added to part A and mixed with stirring at about 80 ° C. until uniform, and then cooled.

Example 21 Shampoo Using the hydrolyzate obtained in Examples 1 to 4, a shampoo having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solutions of Examples 1 to 4 1.00
2 Cocamidopropyl betaine (30%) 30.00
3 Laureth sulfate Na (25%)
14.00
4 Lauryl sulfate Na 1.00
5 Cocamide DEA 1.00
6
Methyl paraben
0.20
7
Phenoxyethanol 0.80
8
Polyquaternium-10 0.60
9
Citric acid 0.05
Ten
Water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 7 were heated to about 70 ° C. and dissolved uniformly (part A). Next, no. 8, no. 10 was heated to about 70 ° C. and dissolved uniformly (part B). Part B was added to part A and mixed uniformly, and then cooled. Furthermore, no. 9 was added and mixed uniformly.

Example 22 Shampoo Using the compound A obtained in Examples 1 to 4, a shampoo having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1 to 4 3.00
2 Cocoa glutamate TEA (27%)
20.00
3 Tetradecenesulfonic acid Na (36%) 1.50
4 PEG120-methyl glucose dioleate 1.50
5 Polyquaternium-10 0.20
6 Methylisothiazolinone 0.01
7 Purified water Total amount of 100 -------------------------------
(Preparation method)
No. 1-4 were heated to about 80 ° C. and dissolved uniformly (part A). Next, no. 5 to 7 were heated to about 80 ° C. and dissolved uniformly (part B). Part B was added to part A and mixed with stirring at about 80 ° C. until uniform, and then cooled.

Example 23 Treatment A treatment having the following formulation was prepared using the hydrolyzed liquid obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
1 Cetanol 8.00
2 Oleyl alcohol
1.00
3 Dimethicone (100cs) 1.00
4 Glyceryl stearate 1.00
5 Plandool-H (Nippon Seika) 1.00
6 Methylparaben 0.20
7 Behentrimonium chloride
2.40
8 Hydrolysis solutions of Examples 1 to 4 1.00
9 Hydroxyethyl cellulose
0.40
Ten
Water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 7 were heated to about 70 ° C. and dissolved uniformly (part A). Next, no. 8 to 10 were heated to about 70 ° C. and dissolved uniformly (part B). Part B was added to part A and stirred and mixed uniformly, and then cooled to room temperature.

Example 24 Treatment Using the hydrolyzate obtained in Examples 1 to 4, treatments having the following formulation were prepared.

Component Blending amount (% by weight)
--------------------------------
1 Cetanol 5.00
2 Oleyl alcohol
1.00
3 Olive oil 2.00
4 Glyceryl stearate
1.00
5 Zicococomonium chloride
0.80
6 Behentrimonium chloride (80%) 2.40
7 Tocopherol 0.05
8 Propylparaben 0.10
9
Methylparaben 0.10
Ten
Hydrolysis solutions of Examples 1-4 2.00
11
Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 10 were heated to about 70 ° C. and dissolved uniformly (part A). No. mixed in Part A 10, 11 were added and stirred and mixed uniformly, and then cooled to room temperature.

Example 25 Styling Gel A styling gel having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
1 STRUCTURE 2001 (made by NSC Japan) 5.00
2 TEA (50%)
3.50
3 AMPHOMER SH30 (made by NSC Japan) 3.00
4 Ethanol (95%)
3.00
5 Methylisothiazoline
0.01
6 Hydrolysis solution of Examples 1-4 2.00
7 Glycolic acid
Appropriate amount
8 TEA
Appropriate amount
9 water
Total amount of 100 --------------------------------
(Preparation method)
No. No. 9 no. 6 is dissolved, and then No. 6 is dissolved. 2, No. 5 is dissolved (part A). No. in part A 1 is gradually added and mixed uniformly (part B). No. No. 3 4 and dissolved in part B cooled to 40 ° C. while mixing and dissolved uniformly. No. 7 or No. 8 adjust the pH to 7.0-7.5.

Example 26 Sunscreen Agent A sunscreen agent having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4
11.70
2 Squalane
22.50
3 LUSPLAN PI-DA (Nippon Seika) 2.70
4 Microcrystalline wax 2.70
5 Distearate Al 1.60
6 Mg stearate 1.60
7 1,3-butylene glycol 5.00
8 Behenyl alcohol 4.80
9 Composite-PC (Nippon Seika) 1.00
Ten
Cholesterol 0.80
11
Propylparaben 0.20
12
Methylparaben 0.20
13
Titanium oxide 9.00
14
Mg sulfate 0.50
15
Purified water 35.70
--------------------------------
(Preparation method)
No. No. 13 2, No. 2 3 was added and kneaded with a mill (part A). No. in a separate container. No. 2 4-6 were added and it heated and dissolved at about 150 degreeC (part B). No. in a separate container. No. 1 No. 7-12 were added, and it heated and dissolved at about 80 degreeC (part C). No. in a separate container. 1, 14, and 15 were added, and it heated and dissolved at about 80 degreeC (part D). Part C was added to part B, mixed, and then added to part A and mixed uniformly. Subsequently, D part was added, it stirred, and it cooled to 40 degreeC after emulsification.

Example 27 Mascara Using the hydrolyzate obtained in Examples 1 to 4, mascara having the following formulation was produced.

Component Blending amount (% by weight)
---------------------------------
1 Iron oxide (black)
10.00
2 Light isoparaffin
30.00
3 Polyacrylate emulsion
30.00
4 Solid paraffin 8.00
5 Hydrolysis solutions of Examples 1-4 1.20
6 Sorbitan sesquioleate 4.00
7 Preservative appropriate amount
8 Perfume appropriate amount
9 Purified water Total amount of 100 ---------------------------------
(Preparation method)
No. No. 9 no. 1 and 5 were added and dispersed with a homomixer. 3 was added and heated to 70 ° C (aqueous phase). The other ingredients were mixed and heated to 70 ° C. (oil phase). The aqueous phase was added to the oil phase, and the mixture was uniformly emulsified and dispersed with a homomixer to obtain the desired mascara.

Example 28 Eyeshadow An eye shadow having the following formulation was produced using the hydrolyzate obtained in Examples 1 to 4.

Component Blending amount (% by weight)
---------------------------------
1 Talc
10.00
2 Kaolin 2.00
3 facial 5.00
4 Hydrolysis solutions of Examples 1 to 4 1.00
5 Stearic acid 3.00
6 Isopropyl myristate 5.00
7 Liquid paraffin 5.00
8 Propylene glycol monolaurate 3.00
9 Antioxidant appropriate amount
Ten
Kasane appropriate amount
11
1,3-butylene glycol 5.00
12
Glycerin 1.00
13
Preservative appropriate amount
14
Triethanolamine 1.20
15
Sequestering agent
16
Purified water Total amount of 100 ---------------------------------
(Preparation method)
No. 1-3 were mixed with a blender and then processed with a pulverizer (powder part). No. 4, 11-16 were dissolved by heating at 70 to 75 ° C. (aqueous phase part). No. 5 to 10 were heated and dissolved at 70 to 80 ° C. (oil phase part). The powder part was added to the aqueous phase part and mixed with stirring. The oil phase was added to this while stirring, dispersed with a homomixer, and stirred and cooled to room temperature to obtain the desired eye shadow.

Example 29 Mild Shampoo A mild shampoo having the following formulation was prepared using the hydrolyzate obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1 to 4 0.50
2 Cocoyl methyl methyl taurine Na (30%) 30.00
3 Cocamidopropyl betaine (30%) 20.00
4 Laureth-12 Na acetate (30%)
5.00
5 1,3-Butylene glycol 1.00
6 Cocamide MEA 2.00
7 Glycol distearate
1.50
8 Polyquaternium-10 0.50
9 Polyquaternium-7 0.30
Ten
Cation NH (Nippon Seika)
0.50
11
Benzoic acid Na 0.40
12
Phenoxyethanol 0.20
13
Methylparaben 0.20
14
Purified water 37.90
--------------------------------
(Preparation method)
No. 2 to 7 were heated to about 80 ° C. and dissolved (part A). No. in a separate container. 1, 8-14 were heated to about 80 ° C. and dissolved (part B). While stirring Part B into Part A, they were gradually added and mixed uniformly, and then rapidly cooled.

EXAMPLE 30 MOISTRINS Using the hydrolyzed solutions obtained in Examples 1 to 4, moistrins having the following formulation were prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4 0.10
2 Plandool-H (Nippon Seika)
0.50
3 Cetrimonium chloride (30%) 5.20
4 Octild decanol 4.70
5 Cetanol 2.80
6 Steartrimonium chloride (63%) 0.60
7 Cetyl octanoate 0.30
8 Squalane 0.30
9 Myristyl sulfate Na 0.20
Ten
Setes-40 0.10
11
Ores-5 0.10
12
Cetyl sulfate Na 0.10
13
Citric acid 0.10
14
Methylparaben 0.10
15
Purified water 84.80
--------------------------------
(Preparation method)
No. 2 to 12 were heated to about 80 ° C. and dissolved (part A). No. in a separate container. 1, 14-15 were heated to about 80 ° C. and dissolved (Part B). While stirring Part B into Part A, gradually add and mix uniformly. After 13 was added and stirred, it was quenched.

Example 31 Treatment A treatment having the following formulation was prepared using the hydrolyzed liquid obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4 2.00
2 Glyceryl stearate (SE) 4.50
3 Steerless-10 4.00
4 Cetanol 4.00
5 Steartrimonium chloride (63%) 1.80
6 LUSPLAN DD-IS (Nippon Seika) 1.50
7 Behentrimonium chloride (80%) 1.00
8 Methylparaben 0.20
9 Purified water
81.00
--------------------------------
(Preparation method)
No. No. 9 was heated to about 80 ° C. 1 and 8 were added and dissolved (part A). No. in a separate container. 2-7 were added, heated and dissolved (part B). Part A was gradually added to part B and mixed uniformly.

Example 32 Straight Perm Agent (Cation Type)
Using the hydrolyzed solutions obtained in Examples 1 to 4, 1 part and 2 parts of a straight permanent agent (cation type) having the following prescription were prepared.

(1 liquid)
Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1 to 4 0.50
2 Setanol
5.00
3 Steartrimonium chloride (63%) 2.40
4 Seths-20 2.40
5 TRIBEHENIN PEG-20 ESTERS 2.00
6 Seths-6 0.80
7 Lauramide MIPA 0.80
8 PEG-60 hydrogenated castor oil 0.40
9 Ammonium thioglycolate solution (50%)
13.50
Ten
Monoethanolamine 1.70
11
Polyquaternium-6 1.30
12
Hydrolyzed soy protein 1.00
13
EDTA-4Na 0.10
14
Ammonia water (28%) 1.10
15
Purified water 67.00
--------------------------------
(Preparation method)
No. Most of 15 were heated to about 80 ° C. (Part A). No. in a separate container. 2 to 8 were added and heated to dissolve (Part B). No. in a separate container. No.15, no. 1, 9-13 were added and dissolved uniformly (part C). Part B was added to part A, mixed and stirred, and part C was added at about 45 ° C. and mixed uniformly. After cooling to room temperature, no. 14 was added.

(2 liquids)
Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4 2.00
2 Setanol
5.00
3 Emmacol VT-20 (Sanei Chemical) 5.00
4 Dimethicone (200cs) 2.00
5 Trioctanoin 2.00
6 Octyldodecanol 0.60
7 Seths-20 0.50
8 Diammonium phosphate 0.20
9 Sodium benzoate 0.15
Ten
Na bromate 8.00
11
Purified water 74.55
--------------------------------
(Preparation method)
No. 2-7 were added, and it heated and dissolved at about 70 degreeC (part A). No. in a separate container. No. 11 was taken and heated to about 70 ° C. 1, 8, and 9 were added and dissolved (part B). No. in a separate container. No. 11 was taken and heated to about 60 ° C. 10 was added and dissolved (part C). At about 70 ° C., part B was added to part A and stirred until the viscosity increased. The mixture was cooled to 60 ° C., and part C was added with stirring and mixed uniformly. After the temperature dropped to about 50 ° C., it was rapidly cooled.

Example 33 Massage cream The massage cream of the following prescription was prepared using the hydrolysis liquid obtained in Examples 1-4.

Component Blending amount (% by weight)
---------------------------------
1 Hydrolysis solution of Examples 1-4 4.00
2 YOFCO-MAS (Nippon Seika Co., Ltd.) 8.00
3 Glyceryl stearate (SE) 2.00
4 Polysorbate 60 1.80
5 Sorbitan stearate 1.00
6 Polyglyceryl stearate-10 0.50
7 Cholesterol 0.20
8 Dimethicone (10cs) 1.00
9 Myristyl alcohol 1.00
Ten
Stearic acid 1.00
11
Stearyl alcohol 0.50
12
Behenyl alcohol 0.50
13
Hydrogenated palm oil 9.00
14
Tocopherol 0.10
15
Isostearyl palmitate 2.00
16
Cetyl octanoate 15.00
17
Ethylparaben 0.20
18
Phenoxyethanol 0.20
19
Methylparaben 0.10
20
1,3-butylene glycol 10.00
twenty one
Glycerin 3.00
twenty two
Elastin 0.10
twenty two
Purified water 38.80
---------------------------------
(Preparation method)
No. 2 to 17 were heated to about 70 ° C. and dissolved uniformly (part A). Next, no. 1, 18-22 was heated to about 70 ° C. and dissolved uniformly (part B). To Part A, Part B was added with stirring and emulsified, and then cooled.

Example 34 Emulsion An emulsion having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
---------------------------------
A
Squalane 2.0
YOFCO MAS (Nippon Seika) 1.0
Neosolute-MP (Nippon Seika) 0.5
Stearic acid 2.0
Vaseline 3.0
Cetyl alcohol 1.0
Sorbitan monooleate 2.0
B
White jellyfish polysaccharide (Nihonsei) 0.05
Hydrolysis solutions of Examples 1 to 4 1.0
LIPIDURE-PMB (Japanese fats and oils) 0.01
Hydrolyzed collagen 0.01
Polyethylene glycol 1500 3.0
Platinum (Inovex) 1.0
1,3-butylene glycol 5.0
Triethanolamine 1.0
Perfume, preservatives Appropriate amount of purified water Total amount of 100 -----------------------------
(Preparation method)
B component is heated and dissolved at 80 ° C. (Aqueous phase) A component is mixed and dissolved by heating at 80 ° C (oil phase). The oil phase is gradually added and pre-emulsified while stirring in these aqueous phases. Further, the mixture is uniformly emulsified with an emulsifier and cooled to room temperature.

Example 35 Curling Agent A curling agent having the following formulation was produced using the hydrolyzate obtained in Examples 1-4.

(1 liquid)
Component Blending amount (% by weight)
---------------------------------
1 Cysteamine hydrochloride 2.00
2 DL cysteine 0.40
3 Monoethanolamine 0.90
4 Ammonia water (28%) 0.50
5 POE20 palm oil fatty acid sorbitan 0.50
6 Fragrance 0.10
7 Diallylammonium chloride / acrylic acid copolymer 1.00
8 Emmacol VT-20 (Sanei Chemical) 3.00
9 Ores-20 0.50
Ten
Ores-50 0.20
11 Hydrolysis solutions of Examples 1-4
0.50
12
Lanolin fatty acid octyldodecyl 0.30
13
Sorbitan monostearate 0.20
14
Edetate tetrasodium tetrahydrate 0.10
15
Ammonium phosphate 0.50
16
Purified water Total amount of 100 ---------------------------------
(Preparation method)
No. No. 16 in part (20%) 1 to 3 was added and dissolved, and No. 1 was previously stored in another container. No. 16 in part (10%) What was melt | dissolved by adding 14 and 15 was added at about 40 degreeC, and it was made to melt | dissolve uniformly (part A). In another container, no. The remainder of 16 was warmed to about 75 ° C. (Part B). In another container 8-13 were taken and heated to about 75 ° C. to dissolve (Part C). After adding part B to part C and emulsifying and stirring and mixing well, it was cooled to 40 ° C. and part A was added and stirred uniformly. Next, no. No. 7 was added and stirred. Nos. 5 and 6 were added. 4 was added, and the mixture was stirred and mixed uniformly to adjust the pH to 9.0 to 9.5, thereby obtaining the target curling agent 1 solution.

(2 liquids)
Component Blending amount (% by weight)
----------------------------------
1 EDTA-2Na 0.10
2 Na bromate 4.00
3 Ammonium phosphate 0.50
4 Cationic NH (Nippon Seika) 2.00
5 Cetrinium chloride (30%) 1.00
6 Ores-50 0.20
7 Dimethicone copolyol 0.50
8 Sodium benzoate 0.15
9 Purified water Total amount of 100 -----------------------------------
(Preparation method)
No. 4-7 were heated to about 80 ° C. and dissolved (part A). In another container 9 (70%) and No. 9 1 and 8 were added and heated to about 80 ° C. to dissolve (Part B). In another container, no. No. 9 and No. 9 A few were added and heated to about 50 ° C. to dissolve (Part C). Add part B to part A and mix and stir uniformly to emulsify, then add part C when the temperature reaches 40 ° C., mix well, and adjust the pH to 6.5 to 6.8 at room temperature. Curl agent 2 liquid was obtained.

Example 36 Hair Cream A hair cream having the following formulation was prepared using the hydrolyzate obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4 2.00
2 Cetanol 4.00
3 Dimethicone (500cs)
13.00
4 Glyceryl stearate 2.80
5 Ores-10 phosphate 0.80
6 Glyceryl stearate (SE) 1.60
7 Phenoxyethanol 0.40
8 Methylparaben 0.20
9 10% NaOH 0.60
Ten
Purified water 74.60
--------------------------------
(Preparation method)
No. 2 to 6 were heated to about 80 ° C. and dissolved (part A). No. in a separate container. 1, 7 to 10 were added and heated to about 80 ° C. to dissolve (Part B). Part B was added to part A and mixed with stirring.

Example 37 Hair Cream A hair cream having the following formulation was prepared using the hydrolyzate obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solutions of Examples 1 to 4 1.00
2 Cetanol 4.00
3 Isodecyl neopentanoate
15.00
4 Stearic acid PG (SE) 1.70
5 Glyceryl stearate 2.70
6 Ores-8 phosphate 0.70
7 Phenoxyethanol 0.40
8 Methylparaben 0.20
9 Purified water
74.30
--------------------------------
(Preparation method)
No. 2 to 6 were heated to about 80 ° C. and dissolved (part A). No. in a separate container. 1 and 7-9 were added, and it heated and melt | dissolved at about 80 degreeC (B part). Part B was added to part A and mixed with stirring.

Example 38 Rinse-in shampoo A rinse-in shampoo having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solutions of Examples 1 to 4 1.00
2 Cocamidopropyl betaine (30%) 20.00
3 Lauryl sulfate TEA (40%)
15.00
4 Cocamide DEA 2.00
5 Cocoa glutamate TEA (30%)
30.00
6 Ethylene glycol distearate 1.20
7 Polyquaternium-10 1.60
8 Stearyl trimonium bromide (70%) 0.60
9 Phenoxyethanol 0.20
Ten
Methylparaben 0.20
11
Benzoic acid Na 0.40
12
Purified water 27.80
--------------------------------
(Preparation method)
No. 7, 8 and 12 were heated to about 80 ° C. and mixed with stirring. Next, no. 3 is added and mixed. 2, 4 to 6 were added and mixed with stirring until uniform. 1, 9-11 were added and dissolved.

Example 39 Shampoo Using the hydrolysis liquid obtained in Examples 1 to 4, shampoos having the following formulation were prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4 0.80
2 Nalauryl sulfate (25%)
45.00
3 Olefin (C14-16) sulfonic acid Na (37%) 4.00
4 Cocamidopropyl betaine (30%) 6.00
5 Cocamide DEA 3.40
6 Ethylene glycol distearate 1.80
7 Phenoxyethanol 0.20
8 Methylparaben 0.20
9 Sodium benzoate 0.40
Ten
Concentrated glycerin 2.40
11
10% citric acid
12
Polyquaternium-10 0.80
13
Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 12-13 were heated to about 80 ° C. and dissolved uniformly. Next, no. Add 2-6 and stir and mix at about 80 ° C. until uniform. 1, 7-10 were added and dissolved. 11 to pH 6-7.

Example 40 Treatment A treatment having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4 0.80
2 Setanol
6.00
3 Trioctanoin 1.60
4 Cetyl octanoate 1.60
5 Stearyl trimonium bromide (70%) 0.60
6 Dimethylaminopropylamide stearate 1.00
7 10% citric acid 2.00
8 Purified water
86.40
--------------------------------
(Preparation method)
No. 2 to 6 were heated to about 80 ° C. and dissolved uniformly. Next, No. 2 was heated to about 80 ° C. No. 1 and 8 were added and mixed uniformly. 7 was dissolved.

Example 41 Treatment Using the hydrolyzed liquid obtained in Examples 1 to 4, a treatment having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solutions of Examples 1 to 4 1.00
2 Setanol
6.00
3 Squalane 2.00
4 Trioctanoin 2.00
5 Dimethylaminopropylamide stearate 2.00
6 Cocoamphoacetate Na (30%) 1.60
7 Phenoxyethanol 0.40
8 Lactic acid 0.80
9 Purified water
84.20
--------------------------------
(Preparation method)
No. 2 to 6 were heated to about 80 ° C. and dissolved uniformly (part A). Next, no. 1 and 7-9 were added and it was made to melt | dissolve uniformly (B part). Part B was added to part A and dissolved uniformly.

Example 42 Liquid Foundation A liquid foundation having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4
2 Glyceryl stearate (SE) 1.00
3 Stearic acid PG (SE) 1.00
4 Cetyl octanoate 6.00
5 Tocopherol 0.10
6 Propylparaben 0.10
7 Titanium oxide / iron oxide mixture
18.00
(Toyo Pigment Co., Ltd. FDP-W-007)
8 Mica 7.00
9 Trimethylsiloxysilicate 3.00
Ten
Cyclomethicone 7.00
11
Phenylmethicone 5.00
12
Cellulose gum 0.10
13
Xanthan gum 0.20
14
1,3-butylene glycol 5.00
15
Methylparaben 0.20
16
Purified water 41.30
--------------------------------
(Preparation method)
No. 12 is a part of No. 12. 16 and stirred to give a viscous liquid (Part A). No. 13 for some No. 13 16 and stirred to give a viscous liquid (Part B). Next, no. 2 to 6 and 9 to 11 were added, and the mixture was heated to about 70 ° C. and dissolved (part C). No. 1, 7, 8, 14, 15 and the remaining No. 16 was heated to about 70 ° C. and dissolved (part D). Part D was added to part C with stirring and emulsified, then cooled to about 50 ° C., part A and part B were added and stirred until uniform.

Example 43 Treatment A treatment having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4 2.00
2 Setanol
5.00
3 Olive oil 2.00
4 Behentrimonium chloride (80%) 2.40
5 Distearyldimonium chloride (75%) 0.80
6 Glyceryl stearate 1.00
7 Methylparaben 0.10
8 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 2 to 6 were heated to about 80 ° C. and dissolved uniformly (part A). In another container 1, 7-8 were heated to about 80 ° C. and dissolved uniformly (Part B). B part was gradually added to part A and mixed uniformly.

Example 44 Treatment Using the hydrolyzed liquid obtained in Examples 1 to 4, a treatment having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solutions of Examples 1 to 4 1.00
2 Setanol
5.00
3 Oleyl alcohol 1.00
4 Behentrimonium chloride (80%) 2.40
5 Distearyldimonium chloride (75%) 0.80
6 Glyceryl stearate 1.00
7 Dimethicone (10000cs) 0.20
8 Aminopropyl dimethicone 0.10
9 Methylparaben 0.10
Ten
Citric acid 0.10
11
Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 2 to 8 were heated to about 80 ° C. and dissolved uniformly (part A). In another container 1, 9-11 were heated to about 80 ° C. and dissolved uniformly (Part B). B part was gradually added to part A and mixed uniformly.

Example 45 Leave-on treatment A leave-on treatment (for hair) having the following formulation was prepared using the hydrolyzate obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1 to 4 0.50
2 Diethyl sebacate 1.00
3 Myristyl alcohol 5.00
4 Behenyl alcohol 1.00
5 Oleyl alcohol 1.00
6 Dimethylpropylamide stearate 2.00
7 Cocoamphoacetate Na (30%) 2.00
8 Glyceryl stearate 0.40
9 Myristic acid 0.60
Ten
Phenoxyethanol 0.40
11
Lactic acid 0.60
12
Purified water Total amount of 100 -------------------------------
(Preparation method)
No. 2 to 10 were heated to about 80 ° C. and dissolved (part A). In another container 1, 11, 12 were taken and heated to about 80 ° C. to dissolve (Part B). Part B was gradually added to part A and mixed uniformly.

Example 46 Leave-on treatment A leave-on treatment (for hair) having the following formulation was prepared using the hydrolyzed liquid obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1 to 4 0.50
2 Isopropyl palmitate 4.00
3 Cetanol 5.00
4 Steertrimonium chloride (63%) 3.20
5 Behentrimonium chloride (80%) 1.00
6 Squalane 1.00
7 Glycerin 1.00
8 Methylparaben 0.10
9 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 2 to 7 were heated to about 80 ° C. and dissolved (part A). In another container 1, 8 and 9 were taken and heated to about 80 ° C. to dissolve (Part B). Part B was gradually added to part A and mixed uniformly.

Example 47 Hair Essence Using the hydrolyzate obtained in Examples 1 to 4, a hair essence having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1 to 4 0.50
2 Diethyl sebacate 1.00
3 Cetanol 1.00
4 Steartrimonium chloride (63%) 0.80
5 Zicococomonium chloride (75%) 2.80
6 Solveste tetraoleate-60 1.00
7 PEG-40 hydrogenated castor oil 0.20
8 Methylparaben 0.10
9 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 2 to 7 were heated to about 80 ° C. and dissolved (part A). In another container 1, 8 and 9 were taken and heated to about 80 ° C. to dissolve (Part B). Part B was gradually added to part A and mixed uniformly.

Example 48 Rinse-in Shampoo A rinse-in shampoo having the following formulation was prepared using the hydrolyzate obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solutions of Examples 1 to 4 1.00
2 Cocamidopropyl betaine (30%) 20.00
3 Lauryl sulfate TEA (40%)
15.00
4 Cocamide DEA 2.00
5 Cocoa glutamate TEA (30%)
30.00
6 Ethylene glycol distearate 1.20
7 Dimethicone (10000cs) 0.10
8 Aminopropyl dimethicone 0.10
9 Polyquaternium-10 1.60
Ten
Polyquaternium-7 1.60
11
Stearyl trimonium bromide (70%) 0.60
12
Phenoxyethanol 0.20
13
Methylparaben 0.20
14
Benzoic acid Na 0.40
15
Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 9 to 11 and 15 were heated to about 80 ° C. and mixed with stirring. Next, no. No. 3 was added and stirred. No. 2, 4 to 8 were added and mixed with stirring until uniform. 1, 12-14 were added and dissolved.

Example 49 Hair restorer The hair restorer of the following prescription was prepared using the hydrolysis liquid obtained in Examples 1-4.

Component Blending amount (% by weight)
----------------------------------
Hydrolysis solutions of Examples 1 to 4 0.05
Diethyl sebacate 0.45
Menthol 0.10
Pepper tincture 0.50
Assembly extract 2.00
Ethanol 30.00
Preservative Appropriate amount of perfume Appropriate amount PPG-6 Decyltetradeceth-30 0.30
Purified water Total amount of 100 ----------------------------------
(Production method)
Each component was stirred and mixed uniformly.

Example 50 Anti-aging cream The anti-aging cream of the following prescription was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
----------------------------------
A
Cetyl octanoate 7.00
Batyl isostearate 2.00
PEG-60 glyceryl isostearate 1.50
Hydrogenated palm oil 3.70
Ceramide 2 0.10
Elastin 0.10
Oil-soluble chamomile extract 0.10
Hydrolyzed collagen 0.10
Ethylparaben 0.20
Stearyl alcohol 3.50
Glyceryl stearate (SE) 1.00
Steerless-6 1.50
Distearic acid PEG-8 1.00
Cetanol 1.00
Dimethicone 1.00
Cetyl dimethicone copolyol 0.50
Tocopherol 0.20
B
Nishi Healing Extract 0.05
C
Hydrolysis solutions of Examples 1-4
15.00
Arbutin 0.50
3-O-ethylascorbic acid 0.50
EDTA-3Na 0.10
Polyglutamic acid (Ichimaru Falcos, Bio PGA solution) 0.10
Glycerin 4.00
Bisulfite Na 0.05
Low molecular weight hyaluronic acid (Kupie) 0.05
Methylparaben 0.10
Phenoxyethanol 0.10
BG 6.00
Hydroxide K Appropriate amount of purified water Total amount of 100 ----------------------------------
(Production method)
A was heated to about 80 ° C. and dissolved uniformly (part A). C was heated to about 80 ° C. and dissolved (part C). While stirring with a homomixer at about 80 ° C., part C was gradually added to part A, mixed uniformly after emulsification, cooled to about 40 ° C., B was added and mixed uniformly.

Example 51 Lotion Toner lotion having the following formulation was prepared using the hydrolyzate obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
Glycerin 3.0
Sorbitol 0.01
Trehalose 0.01
Keratosulfuric acid 0.01
Fucoidan 0.01
PCA-2Na 0.01
Proline 0.01
Aspartic acid 0.01
Hydrolyzed collagen 0.01
Low molecular hyaluronic acid (Kupie) 0.01
Wheat proteolytic peptide 0.01
Oligopeptide 0.01
Elastin 0.01
1,2-hexanediol 1.0
Allantoin 0.01
Cephalanthin 0.01
Citric acid 0.01
Na citrate 0.1
Glycyrrhizic acid 2K 0.1
Cellulose gum 0.05
Xanthan gum 0.05
Guar gum 0.05
p-GEMA (Nippon Seika) 0.05
Carbomer
0.05
Hydroxide K
0.04
Sorbitan sesquioleate
0.1
Polyoxyethylene hydrogenated castor oil
0.1
Neosole-Aqua (Nippon Seika)
5.0
White jellyfish polysaccharide (manufactured by Nippon Seika)
0.1
Hyaluronic acid Na
0.1
Tuberose polysaccharide
0.05
Tamarind polysaccharide
0.1
EDTA2Na
0.1
Kinginga extract 0.01
Saiheyan extract
0.01
Arbutin
2.0
Ascorbic acid Na
3.0
Ascorbyl glucoside
2.0
Astaxanthin solution
0.2
Phytopresome-Q10
0.2
Phytopresome-Cera-2
0.2
Phytopresome-Cera-3 0.2
Chamomile extract
0.01
Kumazasa Extract
0.01
Jatoba extract
0.01
Egg shell membrane extract
0.01
Lycopene 0.01
ethanol
10.0
Hydrolysis solutions of Examples 1 to 4 5.0
Preservative
Appropriate amount
Trace purified water
Total amount of 100 --------------------------------
(Preparation method)
Stir and mix each component uniformly.

Example 52 Sunscreen Cosmetics Using the hydrolyzed solutions obtained in Examples 1 to 4, sunscreen cosmetics having the following formulation were prepared.

Component Blending amount (% by weight)
--------------------------------
A
Quaternium-18 Hectorite 1.00
B
Cyclomethicone 13.70
Diphenyl dimethicone 7.00

Dimethicone copolyol 5.50
YOFCO MAS (Nippon Seika) 1.00
C
Silicone-treated fine particle titanium oxide 3.90
Silicone-treated zinc oxide
2.10
D
Stearic acid Al
0.70
Hydroxide Al
0.50
Isononyl isononanoate 2.50
Isodecyl neopentanoate 2.50
E
Trimethylsiloxysilicate 1.20
Dimethicone 0.80
Meticon 0.10
Stearyl glycyrrhetinate 0.02
Sorbitan sesquioleate 2.00
Tocopherol 0.02
F
Hydrolysis solutions of Examples 1-4 2.00
Na chloride 1.00
Methylparaben 0.15
Purified water Total amount of 100 --------------------------------
(Preparation method)
Add A to B and stir. Further, C is added and dispersed using a roller mill. D is heated and melted and added to the mixture of A, B, and C, and E is further added to about 70 ° C. F is warmed and emulsified gradually with stirring into a mixture of A to E. Cool with stirring, stop stirring at 40-35 ° C. and let stand.

Example 53 Bath agent (bubble bath)
Using the hydrolyzed solutions obtained in Examples 1 to 4, bath preparations having the following formulation were prepared.

Component Blending amount (% by weight)
--------------------------------
A
(C12,13) Palace-3 sulfate Na 5.00
Cocamide DEA 2.00
Sulfosuccinic acid (C12-14) Palace-2Na 2.00
1,3-butylene glycol 2.00
Hydrolysis solutions of Examples 1 to 4 1.00
PEG-20 glyceryl triisostearate 1.00
B
Citric acid 0.05
Sodium benzoate 0.20
Blue No. 1
Trace yellow 4
Trace amount C
Purified water Total amount of 100 --------------------------------
(Preparation method)
A is dissolved in a part of C to make it uniform. Add the remaining C and B and knead well.

Example 54 Hair Wax Using the hydrolyzed liquid obtained in Examples 1 to 4, a hair wax having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4 4.00
2 Candelilla Row
2.00
3 Cetanol
8.00
4 mineral oil
18.00
5 Trioctanoin
4.00
6 Microcrystalline wax 2.00
7 Diethyl sebacate 2.00
8 Dimethicone (100cs) 2.00
9 Laureth-2
2.00
Ten
Glyceryl stearate
3.00
11
PEG-40 hydrogenated castor oil 2.00
12
Polyglyceryl diisostearate-3 2.00
13
Concentrated glycerin 6.00
14
1,3-butylene glycol 4.00
15
Phenoxyethanol
0.60
16
Methylparaben 0.20
17
Alcox E-240 (Meisei Chemical Industry) 0.20
18
purified water
38.00
--------------------------------
(Preparation method)
No. 2 to 14 were heated to about 80 ° C. and dissolved (part A). Next, no. 1, 15-18 were heated to about 80 ° C. and dissolved (Part B). While stirring Part B into Part A, it was gradually added and dissolved uniformly.

Example 55 Liquid Face Wash Using the hydrolyzed liquid obtained in Examples 1 to 4, a liquid face wash having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Lauroyl sarcosine Na
12.00
2 Myristoyl methyl taurine Na 2.00
3 Isethionate Na 1.00
4 Polyglyceryl laurate-6 2.00
5 Cocamide DEA 2.00
6 Sorbitol 8.00
7 PEG-30 4.00
8 1,3-butylene glycol 8.00
9 Hydrolysis solution of Examples 1-4 2.00
Ten
Glycerin 5.00
11
Phenoxyethanol 0.80
12
(HEMA glucoside / ethyltrimonium methacrylate chloride)
Copolymer (10%) (Nippon Seika)
1.00
13
Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 3 and 10 were heated to about 80 ° C. and dissolved (part A). No. in part A 1, 2, 4-9, 11-13 were added, heated to about 80 ° C. to dissolve uniformly, and then cooled. No. The prescription excluding only 9 was blank.

Example 56 Body Shampoo A body shampoo having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
1 (HEMA glucoside / ethyltrimonium methacrylate methacrylate)
Copolymer (10%) (Nippon Seika)
2.00
2 Cocoyl Methyl Taurine Na
10.00
3 Lauroyl hydrolyzed silk Na 6.00
4 Lauroylmethylalanine Na
10.00
5 Cocoamphoacetate Na (30%) 4.00
6 Cocamidopropyl betaine (30%)
10.00
7 Cocamide DEA 3.00
8 Hydrolysis solution of Examples 1 to 4 3.00
9 1,3-butylene glycol 5.00
Ten
Methylparaben 0.20
11
Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 8 and a part of No. 11 were heated at about 80 ° C. and mixed uniformly (part A). No. 2-No. 10. The remaining 11 was heated at about 80 ° C. and mixed uniformly (Part B). While stirring, part A was gradually added to part B and mixed uniformly.

Example 57 Body Shampoo A body shampoo having the following formulation was prepared using the hydrolyzate obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1 to 4 0.50
2 Cetealess-60 myristyl glycol 2.00
3 DEA Lauric acid (1: 1 type) 5.00
4 Propylparaben 0.10
5 Methylparaben 0.20
6 Potassium soap base solution
40.00
7 Lauroylmethylalanine Na (30%)
10.00
8 Lactic acid
0.70
9 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1-No. 5 was heated at about 70 ° C. and mixed uniformly (part A). No. No. 8 9 was dissolved in part (B part). While stirring, No. 6, no. 7, no. The remainder of 9 and part B were gradually added and mixed uniformly. No. The prescription except 1 was used as a blank.

Example 58 Body Shampoo A body shampoo having the following formulation was prepared using the hydrolyzate obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
1 (HEMA glucoside / ethyltrimonium methacrylate methacrylate)
Copolymer (10%) (Nippon Seika)
2.00
2 Lauryl phosphate
20.00
3 Cocamidopropyl betaine (30%)
10.00
4 Lauroylmethylalanine Na 6.00
5 Cocamide DEA 2.00
6 Hydrolysis solution of Examples 1-4 2.00
7 Distearic acid PEG-150 1.00
8 Glycerin 4.00
9 Sodium benzoate 0.40
Ten
Phenoxyethanol 0.20
11
Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 and a part of No. 11 were heated at about 80 ° C. and mixed uniformly (part A). No. 2-No. 10. The remaining 11 was heated at about 80 ° C. and mixed uniformly (Part B). While stirring, part A was gradually added to part B and mixed uniformly.

Example 59 Face Wash Liquid Using the hydrolyzate obtained in Examples 1 to 4, a face wash liquid having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
Lipidure PMB (Japanese fat)
1.00
Hydrolysis solutions of Examples 1 to 4 1.00
Dipotassium glycyrrhizinate
0.05
Palm oil fatty acid diethanolamide 4.00
N-coconut oil fatty acid acyl-L-glutamic acid triethanolamine 1.50
Coconut oil fatty acid amidopropyl betaine

8.10
N-coconut oil fatty acid acyl-DL-alanine triethanolamine 1.50
Preservative Appropriate amount Sodium monohydrogen phosphate anhydrous 1.00
citric acid
0.15
purified water
Total amount of 100 --------------------------------
(Preparation method)
Warm to 40-50 ° C and stir to homogenize.

Example 60 Face Wash Foam A face wash foam having the following formulation was prepared using the hydrolyzate obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
1
(Coconut fatty acid / hydrogenated beef tallow fatty acid) glutamic acid Na 20.00
2
1,3-butylene glycol 14.00
Three
Plandool-H (Nippon Seika) 1.00
Four
PEG-8 5.00
Five
PEG-30 10.00
6
Lauric acid diethanolamide
2.00
7
Propylparaben 0.10
8
Methylparaben 0.20
9
Lipidure PMB (Japanese fat)
1.00
10 Crystalline cellulose 10.00
11 Hydrolysis solutions of Examples 1-4
5.00
12 Tocopherol 0.20
13 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1-8 are heated to about 80 ° C. and dissolved. No. after dissolution Add 11-13 and dissolve. While stirring at about 60 ° C., no. Add 9, 10 and cool to about 40 ° C.

Example 61 Soap A soap having the following formulation was prepared using the hydrolyzed liquid obtained in soap examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
Shiken base
Amount of lauric acid that totals 100

5.00
1,3-butylene glycol 3.00
Hydrolysis solutions of Examples 1-4
5.00
Plandool-H (Nippon Seika) 0.05
Titanium oxide 1.00
Etidronic acid
0.10
Edetate
0.10
Yellow No. 205
Trace amount --------------------------------
(Preparation method)
All components are dissolved by heating to 80 ° C., cooled with stirring, poured into molds and left to stand.

Example 62 A facial cleanser having the following formulation was prepared using the hydrolyzate obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
A
Plandool-H (Nippon Seika)
0.20
Jojoba oil 0.10
Squalane 0.10
Cocamide DEA 2.00
Lauramide DEA 3.00
Tocopherol 0.20
Propylparaben 0.10
B
Hydrolysis solutions of Examples 1 to 4 0.50
Distearate glycol 1.00
Lauroylmethylalanine Na (30%) 10.00
Coconut fatty acid K, myristic acid K (40%)
40.00
BG 3.50
1,5-pentanediol 0.50
1,2-hexanediol 0.30
PEG-20 5.00
PEG-400 5.00
Citric acid 0.50
Methylparaben 0.20
Cetealess 60 myristyl glycol
2.00
purified water
Total amount of 100 --------------------------------
(Preparation method)
A was heated to about 80 ° C. and dissolved. B was heated to about 80 ° C. and dissolved. B was added to A with stirring and emulsified, and then cooled to about 40 ° C.

Example 63 Body Soap A body soap having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4
0.50
2 Potassium soap base solution
40.00
3 Lauroylmethylalanine Na (30%)
10.00
4 Lauramide DEA 5.00
5 Ethylene glycol distearate 1.50
6 BG 5.00
7 Propylparaben 0.10
8 Methylparaben 0.20
9 Lactic acid
0.70
Ten
Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1-No. 10 was dissolved by heating at about 80 ° C. and cooled with stirring.

Example 64 Styling Gel A styling gel having the following formulation was prepared using the hydrolyzate obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4
2 Diethoxyethyl succinate 2.00
3 STRUCTURE 2001 (made by NSC Japan) 7.00
4 TEA (50%)
3.00
5 AMPHOMER SH-10 (made by NSC Japan) 3.00
6 Ethanol (95%)
1.00
7 Methylisothiazoline
0.01
8 Glycolic acid
Appropriate amount
9 TEA
Appropriate amount
Ten
purified water
Total amount of 100 --------------------------------
(Preparation method)
No. 1, no. 2, No. 7 and No. 10 are heated to about 60 ° C. and dissolved. Furthermore, no. 3 is added and dispersed, then No. 4 is added to increase the viscosity and cooled to 40 ° C. (Part A). No. 5, no. 6 is mixed uniformly, added to part A, and mixed uniformly. No. 8 or No. 9 to adjust the pH to 7.2-7.5.

Example 65 Tablet Using the hydrolyzed liquid obtained in Examples 1 to 4, tablets having the following formulation were prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1 to 4 0.05
2 dried corn starch
29.0
3 Carboxymethylcellulose
20.0
4 Microcrystalline cellulose

40.0
5 Polyvinylpyrrolidone 7.0
6 Talc
3.0
7 White jellyfish polysaccharide (Nippon Seika) 0.05
--------------------------------
(Preparation method)
No. Mix 1-5, then add 10% water as binder, extrude granulate and dry. No. of the molded granules. Add 6 and mix to tablet.

Example 66 Ointment A styling gel having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1 to 4 1.0
2 Polyoxyethylene cetyl ether (30E.O.)
2.0
3 Glycerol monostearate
10.0
4 Liquid paraffin
5.0
5 Cetanol 6.0
6 Methyl paraoxybenzoate
0.1
7
Propylene glycol
10.0
8
White jellyfish polysaccharide (Nihonsei) 0.05
9
Purified water Amount to be 100 in total --------------------------------
(Preparation method)
No. 2 to 5 are dissolved by heating and mixed, and kept at 70 ° C. to obtain an oil phase. No. 1, 6-8 are dissolved by heating and mixed, and kept at 75 ° C. to obtain an aqueous phase. The aqueous phase is added to the oil phase to emulsify, and cooled to 30 ° C. while mixing.

Example 67 A styling gel having the following formulation was prepared using the hydrolyzate obtained in Beverage Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4
2 White jellyfish polysaccharide (Nippon Seika) 0.02
3 Stevia

29.0
4 Malic acid
20.0
5 Fragrance
40.0
6 Purified water Amount to be 100 in total amount --------------------------------
(Preparation method)
No. Dissolve 2 and 3 in a small amount of water. No. 1, 4-5 were added and mixed.

Example 68 Foundation Using the hydrolyzed solutions obtained in Examples 1 to 4, foundations having the following formulation were prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1 to 4 6.00
2 Cyclomethicone 3.50
3 Dimethicone (5cs) 2.00
4 Trimethylsiloxysilicic acid 1.50
5 Octyl methoxycinnamate 1.00
6 Phenoxyethanol 0.40
7 Tocopherol 0.10
8 Mica
39.60
9 Talc
24.00
Ten
Titanium oxide 20.00
11
Iron oxide 1.90
--------------------------------
(Preparation method)
Each component was stirred at high speed and mixed uniformly.

Example 69 Solid Powdery Foundation Using the hydrolyzed liquid obtained in Examples 1 to 4, a solid powdered foundation having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4
10.00
2 Perfluoropolyether 5.00
3 Silicone-treated sericite
60.00
4 Titanium oxide
10.00
5 Powdered synthetic hydrocarbon wax 1.00
6 Yellow iron oxide 1.00
7 Bengala 0.50
8 Methylparaben 0.50
9 Black iron oxide 0.05
Ten
Talc Total amount of 100 --------------------------------
(Preparation method)
No. 1 and 2 are heated to about 70 ° C. and mixed (part A). No. in a separate container. Take 3 to 10 and mix and disperse (Part B). Add part A to part B and mix evenly.

Example 70 Foundation Using the hydrolyzate obtained in Examples 1 to 4, a foundation having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1 to 4 6.00
2 Mica
39.50
3 Talc
24.00
4 Titanium oxide
20.00
5 Iron oxide 1.90
6 Cyclomethicone 3.50
7 Trimethylsiloxysilicic acid 1.50
8 Octyl methoxycinnamate 1.00
9 Dimethicone (10cs) 2.00
Ten
Tocopherol 0.20
11
Phenoxyethanol 0.40
--------------------------------
(Preparation method)
No. 1 to 11 were mixed uniformly.

Example 71 Tablets Tablets having the following formulation were prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1-4 0.10
2 dried corn starch
50.00
3 Erythritol
40.00
4 Citric acid
5.00
5 Sucrose fatty acid ester 3.00
6 Perfume appropriate amount
7 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. Mix 1-4 and 7 and granulate. No. of the molded granules. Add 5 and 6 and tablet.

Example 72 Pack Using the hydrolyzate obtained in Examples 1 to 4, a pack having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Hydrolysis solution of Examples 1 to 4 6.00
2 Polyvinyl alcohol
39.50
3 Ethanol
24.00
4 1,3-butylene glycol
20.00
5 Methyl paraoxybenzoate 1.90
6 Polyoxyethylene hydrogenated castor oil (20E.O.)
3.50
7 Citric acid 1.50
8 Sodium citrate 1.00
9 Fragrance 2.00
Ten
White jellyfish polysaccharide (Nippon Seika) 1.00
11
Purified water 0.20
--------------------------------
(Preparation method)
No. 1 to 11 were dissolved uniformly.

Example 73 Cream A cream having the following formulation was prepared using the hydrolyzate obtained in Examples 1-4.

Component Blending amount (% by weight)
--------------------------------
(Part A)
BG 8.0
Glycerin 5.0
Phytocompo-PP (Nippon Seika Co., Ltd.) 0.5
(Part B)
Neosolute-MP 1.0
YOFCO MAS (Nippon Seika Co., Ltd.) 6.0
Purified olive squalane (Nikko Chemicals) 0.1
Retinol palmitate 0.5
Isocetyl myristate 4.0
Cetyl palmitate 1.5
Batyl isostearate 1.5
Hardened oil 3.0
Stearyl alcohol 2.8
Cetanol 0.8
Polyoxyethylene glyceryl isostearate 1.2
Polyoxyethylene stearyl ether 1.2
Self-emulsifying glyceryl monostearate0.8
Polyethylene glycol distearate0.8
Cetyl dimethicone copolyol 0.4
Methylpolysiloxane 1.5
δ-tocopherol 0.2
Ethylparaben 0.15
(C section)
Hydrolysis solutions of Examples 1-4
L-Hydroxyproline 0.05
Marine Collagen Peptide (Nikko Chemicals) 0.05
NIKKOL OCELASTIN (manufactured by Nikko Chemicals)
0.05
Pomegranate extract 0.05
Plantage <White> (Maruzen Pharmaceutical) 0.05
Soiact-W (Nikko Chemicals) 0.05
Hydrolyzed collagen 0.1
Citric acid 0.01
Na citrate 0.09
Methylparaben 0.1
Arbutin (Nippon Seika) 1.0
Blueberry extract B 0.1
Kinginga extract-J 0.1
Phenoxyethanol 0.2
Methylparaben 0.1
Carbomer 0.25
Hydroxide K 0.2
Perfume Small amount of purified water Total amount of 100 --------------------------------
(Preparation method)
Part A is heated to about 70 ° C. and dispersed uniformly. Part B is heated to about 80 ° C. and dissolved uniformly. Add part C and stir well to make uniform. Add Part B to Part A, gradually add Part C heated to about 80 ° C. while stirring with a homomixer at about 80 ° C., mix uniformly after emulsification, and cool to about 40 ° C.

Example 74 Whitening beauty essence Using the hydrolysis liquid obtained in Examples 1 to 4, a whitening beauty essence having the following formulation was prepared.

Component Blending amount (% by weight)
--------------------------------
1 Arbutin 3.00
2 Glycerin
8.00
3 1,3-Butylene glycol 2.00
4 Hydrogenated lecithin
0.05
5 Hydrolysis solutions of Examples 1-4
0.10
6 Hydroxyethyl cellulose
0.06
7 PEG-50 hydrogenated castor oil 0.50
8 Sodium citrate
9 Methyl benzoate
0.21
Ten
Phenoxyethanol
0.08
11
EDTA-4Na 0.10
12
Tocopherol
0.05
13
Low molecular hyaluronic acid (Kupie) 0.50
14
3-0-ethylascorbic acid 0.50
15
Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 15 were dissolved uniformly.

Example 75 Anti-aging cream An anti-aging cream having the following formulation was prepared using the hydrolyzate obtained in Examples 1 to 4.

Component Blending amount (% by weight)
--------------------------------
A
Plandool-G (Nippon Seika) 10.0
Neosole-Aqua (Nippon Seika)
5.0
Cetyl octanoate 5.0
Trioctanoin (Nippon Seika)
2.0
Batyl isostearate
2.0
PEG-60 glyceryl isostearate
1.5
Jojoba oil
1.0
Hydrogenated jojoba oil
1.0
Squalane
1.0
Hydrogenated palm oil
3.7
Ceramide 3
0.1
Lauroyl sarcosine isopropyl 0.5
Retinol
0.1
Oil soluble licorice extract
0.5
Oil-soluble chamomile extract
0.5
Ethyl paraben
0.2
Stearyl alcohol
3.5
Glyceryl stearate (SE)
1.0
Steerless-6
1.5
PEG-8 distearate
1.0
Cetanol
1.0
Dimethicone
1.0
Polyether modified silicone
0.5
Tocopherol
0.2
B
Saiheyan extract
0.05
Peach leaf extract
0.05
Kashiwa leaf extract
0.05
Egg shell membrane extract
0.05
C
Arbutin
3.0
3-O-ethylascorbic acid 3.0
Glycyrrhizic acid 2K
0.05
Glycyrrhetinic acid
0.05
Allantoin
0.05
Butyl resorcinol
0.5
β-cyclodextrin
0.5
Serine
0.1
Alanine
0.1
Arginine
0.1
Betaine
0.1
Sohakuhi extract
0.1
Pyrrolidone carboxylic acid
0.1
Chondroitin sulfate Na
0.01
α-Lipoic acid
0.1
EDTA-3Na
0.1
Polyglutamic acid (Ichimaru Falcos, Bio PGA solution) 0.1
Phytopresome Cera-2 (Nippon Seika)
(Phospholipid / phytosterol / ceramide complex) 0.3
Glycerin
1.0
Diglycerin
1.0
Polyglycerin-10
0.2
Trehalose
0.5
Sulfurous acid Na
0.05
Bisulfite Na
0.05
1,2-hexanediol
0.5
1,2-pentanediol
0.5
BG
5.0
β-glucan
0.1
Heparin and derivatives
0.1
Albumin 0.1
Methylcellulose
0.1
citric acid
0.05
Fumaric acid
0.05
White jellyfish polysaccharide (Nippon Seika)
0.05
Hydrolysis solutions of Examples 1-4
10.00
Platinum (Inovex) 1.0
Hydroxide K
Appropriate amount of purified water
Total amount of 100 --------------------------------
(Preparation method)
A was heated to about 80 ° C. and dissolved uniformly (part A). C was heated to about 80 ° C. and dissolved (part C). While stirring with a homomixer at about 80 ° C., part C was gradually added to part A, mixed uniformly after emulsification, cooled to about 40 ° C., B was added and mixed uniformly.

Example 76 Cream An anti-aging cream having the following formulation was prepared using the hydrolyzate obtained in Examples 1 to 4.

Component Blending amount (% by weight)
----------------------------------
A
Neosolue-DE (Nippon Seika) 2.0
Cetyl octanoate 7.00
Batyl isostearate 2.00
PEG-60 glyceryl isostearate 1.50
Hydrogenated palm oil 3.70
Ceramide 2 0.10
Elastin 0.10
Oil-soluble chamomile extract 0.10
Hydrolyzed collagen 0.10
Ethylparaben 0.20
Stearyl alcohol 3.50
Glyceryl stearate (SE) 1.00
Steerless-6 1.50
Distearic acid PEG-8 1.00
Cetanol 1.00
Dimethicone 1.00
Cetyl dimethicone copolyol 0.50
Tocopherol 0.20
B
Nishi Healing Extract 0.05
C
White jellyfish polysaccharide (Nihonsei) 0.05
Hydrolysis solutions of Examples 1-4
15.00
Arbutin 0.50
3-O-ethylascorbic acid 0.50
EDTA-3Na 0.10
Polyglutamic acid (Ichimaru Falcos, Bio PGA solution) 0.10
Glycerin 4.00
Bisulfite Na 0.05
Low molecular weight hyaluronic acid (Kupie) 0.05
Methylparaben 0.10
Phenoxyethanol 0.10
BG 6.00
Hydroxide K Appropriate amount of purified water Total amount of 100 ----------------------------------
(Production method)
A was heated to about 80 ° C. and dissolved uniformly (part A). C was heated to about 80 ° C. and dissolved (part C). While stirring with a homomixer at about 80 ° C., part C was gradually added to part A, mixed uniformly after emulsification, cooled to about 40 ° C., B was added and mixed uniformly.

Example 77 Cosmetic liquid The cosmetic liquid of the following prescription was prepared using the hydrolyzate obtained in Examples 1-4.
Component Blending amount (% by weight)
----------------------------------
Glycerin 5.0
BG 8.0
Phytopresome (Nippon Seika) 0.2
Phytopresome Q10 (Nippon Seika) 0.5
Phytopresome Cera-2 (Nippon Seika) 0.2
Phytopresome Cera-3 (Nippon Seika) 0.2
Neosole-Aqua (Nippon Seika)
5.0
Phenoxyethanol 0.2
Methylparaben 0.1
Dipotassium glycyrrhizinate 0.2
Xanthan gum 0.2
Carbomer 0.25
Hydroxide K 0.2
White jellyfish polysaccharide (manufactured by Nippon Seika) 0.2
Hydrolysis solutions of Examples 1 to 4 3.0
KPA-CU (Grape Seed Extract) (Nikko Chemicals) 0.05
Hydrolyzed collagen 0.05
Low molecular weight hyaluronic acid 0.1
Citric acid 0.01
Na citrate 0.09
Blueberry extract B 0.1
Kinginga extract-J 0.1
L-Hydroxyproline 0.05
Marine Collagen Peptide (Nikko Chemicals) 0.05
NIKKOL OCELASTIN (Nikko Chemicals) 0.05
Pomegranate extract 0.05
Plantage <White> (Maruzen Pharmaceutical) 0.05
Soiact-t (Nikko Chemicals) 0.05
Platinum (Platinum Gensui, Inovex) 0.05
Purified water Total amount of 100 ----------------------------------
(Preparation method)
Stir and mix each component uniformly.

Example 78 Milky lotion Using the hydrolyzate obtained in Examples 1 to 4, a cosmetic liquid having the following formulation was prepared.
Component Blending amount (% by weight)
----------------------------------
A
Plandool-G (Nippon Seika) 1.0
Neosolute-MP (Nippon Seika) 2.0
Presome CS2-101 (Nippon Seika) 1.4
Presome Cera-2 (Nippon Seika) 0.1
Ceramide 2 0.01
Stearic acid 2.0
Vaseline 3.0
Cetyl alcohol 1.0
Sorbitan monooleate 2.0
Polyethylene glycol 1500 3.0
B
1,3-butylene glycol 3.0
Glycerin 1.5
Hydrolyzate of Examples 1 to 4 1.5
3-O-ethylascorbic acid 1.0
Maltose 1.0
Sorbitol 0.5
Trehalose 0.5
Triethanolamine 1.0
Perfume, preservatives Appropriate amount of purified water Total amount of 100 -----------------------------
(Preparation method)
The component B is heated and dissolved at 80 ° C. (aqueous phase). A component is mixed and it heat-dissolves at 80 degreeC (oil phase). The oil phase is gradually added and pre-emulsified while stirring in these aqueous phases. Further, the mixture is uniformly emulsified with an emulsifier and cooled to room temperature.

Claims (3)

  Antioxidant characterized by containing hydrolyzate of water-soluble polysaccharide extracted from fruit body or fungus body of white jellyfish   The antioxidant according to claim 1, which has an action of removing active oxygen or scavenging or scavenging free radicals. The antioxidant according to claim 1 or 2, wherein the hydrolyzate has a weight average molecular weight of 1,000 to 100,000.