JP5753466B2 - Liquid cosmetics - Google Patents
Liquid cosmetics Download PDFInfo
- Publication number
- JP5753466B2 JP5753466B2 JP2011200427A JP2011200427A JP5753466B2 JP 5753466 B2 JP5753466 B2 JP 5753466B2 JP 2011200427 A JP2011200427 A JP 2011200427A JP 2011200427 A JP2011200427 A JP 2011200427A JP 5753466 B2 JP5753466 B2 JP 5753466B2
- Authority
- JP
- Japan
- Prior art keywords
- oil
- mass
- acid
- cosmetic
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000002537 cosmetic Substances 0.000 title claims description 45
- 239000007788 liquid Substances 0.000 title claims description 25
- 239000003921 oil Substances 0.000 claims description 47
- WNWHHMBRJJOGFJ-UHFFFAOYSA-N 16-methylheptadecan-1-ol Chemical compound CC(C)CCCCCCCCCCCCCCCO WNWHHMBRJJOGFJ-UHFFFAOYSA-N 0.000 claims description 32
- -1 polyoxyethylene Polymers 0.000 claims description 31
- 238000002156 mixing Methods 0.000 claims description 25
- 239000004094 surface-active agent Substances 0.000 claims description 23
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 21
- 239000004359 castor oil Substances 0.000 claims description 13
- 235000019438 castor oil Nutrition 0.000 claims description 13
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 13
- 229940079593 drug Drugs 0.000 claims description 9
- 239000003814 drug Substances 0.000 claims description 9
- CUNWUEBNSZSNRX-RKGWDQTMSA-N (2r,3r,4r,5s)-hexane-1,2,3,4,5,6-hexol;(z)-octadec-9-enoic acid Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O CUNWUEBNSZSNRX-RKGWDQTMSA-N 0.000 claims description 4
- 229960005078 sorbitan sesquioleate Drugs 0.000 claims description 4
- JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical compound OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 claims description 3
- 235000019198 oils Nutrition 0.000 description 45
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 18
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 14
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical class OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 13
- 238000011156 evaluation Methods 0.000 description 13
- 239000000203 mixture Substances 0.000 description 13
- 150000003839 salts Chemical class 0.000 description 13
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 description 12
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 12
- 239000006210 lotion Substances 0.000 description 12
- 235000011187 glycerol Nutrition 0.000 description 9
- 239000000843 powder Substances 0.000 description 9
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 description 8
- 230000000052 comparative effect Effects 0.000 description 8
- 239000000284 extract Substances 0.000 description 8
- 230000008014 freezing Effects 0.000 description 8
- 238000007710 freezing Methods 0.000 description 8
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical class NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 description 8
- 229960005070 ascorbic acid Drugs 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- 229960000401 tranexamic acid Drugs 0.000 description 7
- 239000001993 wax Substances 0.000 description 7
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 6
- 239000002211 L-ascorbic acid Substances 0.000 description 6
- 235000000069 L-ascorbic acid Nutrition 0.000 description 6
- 239000004166 Lanolin Substances 0.000 description 6
- 239000008346 aqueous phase Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 235000019388 lanolin Nutrition 0.000 description 6
- 229940039717 lanolin Drugs 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 229920000642 polymer Polymers 0.000 description 6
- 238000003860 storage Methods 0.000 description 6
- 239000002253 acid Substances 0.000 description 5
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 5
- 239000012071 phase Substances 0.000 description 5
- 239000000049 pigment Substances 0.000 description 5
- 229920001223 polyethylene glycol Polymers 0.000 description 5
- 206010016322 Feeling abnormal Diseases 0.000 description 4
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 4
- 235000015278 beef Nutrition 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 238000007796 conventional method Methods 0.000 description 4
- 235000014113 dietary fatty acids Nutrition 0.000 description 4
- 239000000839 emulsion Substances 0.000 description 4
- 239000000194 fatty acid Substances 0.000 description 4
- 229930195729 fatty acid Natural products 0.000 description 4
- 230000007774 longterm Effects 0.000 description 4
- 239000002304 perfume Substances 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 239000001509 sodium citrate Substances 0.000 description 4
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 4
- 239000004711 α-olefin Substances 0.000 description 4
- HOVAGTYPODGVJG-UVSYOFPXSA-N (3s,5r)-2-(hydroxymethyl)-6-methoxyoxane-3,4,5-triol Chemical compound COC1OC(CO)[C@@H](O)C(O)[C@H]1O HOVAGTYPODGVJG-UVSYOFPXSA-N 0.000 description 3
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 3
- IZZIWIAOVZOBLF-UHFFFAOYSA-N 5-methyloxysalicylic acid Natural products COC1=CC=C(O)C(C(O)=O)=C1 IZZIWIAOVZOBLF-UHFFFAOYSA-N 0.000 description 3
- 239000004386 Erythritol Substances 0.000 description 3
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 229920002472 Starch Polymers 0.000 description 3
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 239000002585 base Substances 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 229920002678 cellulose Polymers 0.000 description 3
- 239000001913 cellulose Substances 0.000 description 3
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 3
- 235000019414 erythritol Nutrition 0.000 description 3
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 description 3
- 229940009714 erythritol Drugs 0.000 description 3
- 150000002148 esters Chemical class 0.000 description 3
- 150000004665 fatty acids Chemical class 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- HOVAGTYPODGVJG-UHFFFAOYSA-N methyl beta-galactoside Natural products COC1OC(CO)C(O)C(O)C1O HOVAGTYPODGVJG-UHFFFAOYSA-N 0.000 description 3
- 239000010445 mica Substances 0.000 description 3
- 229910052618 mica group Inorganic materials 0.000 description 3
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 229960005323 phenoxyethanol Drugs 0.000 description 3
- 229940105297 polyglyceryl-2 diisostearate Drugs 0.000 description 3
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical group OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 3
- 239000008107 starch Substances 0.000 description 3
- 235000019698 starch Nutrition 0.000 description 3
- 235000000346 sugar Nutrition 0.000 description 3
- 239000003760 tallow Substances 0.000 description 3
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 3
- WXTMDXOMEHJXQO-UHFFFAOYSA-N 2,5-dihydroxybenzoic acid Chemical compound OC(=O)C1=CC(O)=CC=C1O WXTMDXOMEHJXQO-UHFFFAOYSA-N 0.000 description 2
- AUZQQIPZESHNMG-UHFFFAOYSA-N 3-methoxysalicylic acid Chemical compound COC1=CC=CC(C(O)=O)=C1O AUZQQIPZESHNMG-UHFFFAOYSA-N 0.000 description 2
- MRIXVKKOHPQOFK-UHFFFAOYSA-N 4-methoxysalicylic acid Chemical compound COC1=CC=C(C(O)=O)C(O)=C1 MRIXVKKOHPQOFK-UHFFFAOYSA-N 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- OVBJJZOQPCKUOR-UHFFFAOYSA-L EDTA disodium salt dihydrate Chemical compound O.O.[Na+].[Na+].[O-]C(=O)C[NH+](CC([O-])=O)CC[NH+](CC([O-])=O)CC([O-])=O OVBJJZOQPCKUOR-UHFFFAOYSA-L 0.000 description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical group C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 description 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 2
- MLSJBGYKDYSOAE-DCWMUDTNSA-N L-Ascorbic acid-2-glucoside Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)=C1O MLSJBGYKDYSOAE-DCWMUDTNSA-N 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- 235000019482 Palm oil Nutrition 0.000 description 2
- 235000002953 Saxifraga stolonifera Nutrition 0.000 description 2
- 244000288377 Saxifraga stolonifera Species 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 235000009108 Urtica dioica Nutrition 0.000 description 2
- 244000274883 Urtica dioica Species 0.000 description 2
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 2
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 125000003545 alkoxy group Chemical group 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
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- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
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- NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 description 2
- UKMSUNONTOPOIO-UHFFFAOYSA-N docosanoic acid Chemical compound CCCCCCCCCCCCCCCCCCCCCC(O)=O UKMSUNONTOPOIO-UHFFFAOYSA-N 0.000 description 2
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- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 description 2
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- 150000002632 lipids Chemical class 0.000 description 2
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 2
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 2
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- YRJKYHIIYRGTCC-UHFFFAOYSA-M potassium;2-hydroxy-4-methoxybenzoate Chemical compound [K+].COC1=CC=C(C([O-])=O)C(O)=C1 YRJKYHIIYRGTCC-UHFFFAOYSA-M 0.000 description 2
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- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/26—Optical properties
- A61K2800/262—Transparent; Translucent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Description
本発明は、透明から半透明の液状化粧料に関する。より詳細には、べたつきがなくやわらかな使用感触を有し、なおかつ凍結、高温などの過酷な条件下での安定性にも優れた液状化粧料に関する。 The present invention relates to a transparent to translucent liquid cosmetic. More specifically, the present invention relates to a liquid cosmetic that has a soft feel without stickiness and is excellent in stability under severe conditions such as freezing and high temperature.
近年、油分を微粒子化して配合した化粧料は、肌に優しい感触を与え、皮膚への高い浸透性を示すことから、嗜好に応じた使用感触と肌改善効果を幅広く実現できるという利点を有している。しかしながら、かかる構成の化粧料は、経時安定性及び製造の簡便性という点で問題があった。 In recent years, cosmetics formulated with finely divided oils have the advantage of being able to realize a wide range of use feelings and skin improvement effects according to tastes because they give skin-friendly feel and show high permeability to the skin. ing. However, cosmetics having such a configuration have problems in terms of stability over time and ease of production.
特許文献1は、油分を微粒子化した外観上半透明から透明の液状化粧料を開示しており、(a)常温で液状の分岐飽和脂肪酸が1.0〜80.0重量%を占める油分を0.01〜3重量%と、(b)親水性界面活性剤とを配合することにより、長期安定性及び振動安定性に優れる化粧水状の化粧料が得られると記載している。 Patent Document 1 discloses a liquid cosmetic material which is semitransparent to transparent in appearance with finely divided oil, and (a) an oil in which a branched saturated fatty acid which is liquid at room temperature accounts for 1.0 to 80.0% by weight. It describes that a lotion-like cosmetic having excellent long-term stability and vibration stability can be obtained by blending 0.01 to 3% by weight and (b) a hydrophilic surfactant.
特許文献2には、(a)イソステアリン酸が34質量%以上を占める油分を0.01〜2質量%、(b)特定の親水性界面活性剤を0.04〜1.0質量%、及び(c)特定の親油性界面活性剤を0.001〜0.75質量%配合した、外観上白濁した液状化粧料が記載されており、白濁を維持しながら界面活性剤の配合量を抑制してさっぱりした使用感を持ち、なおかつ長期安定性及び振動安定性に優れるとされている。 In Patent Document 2, (a) 0.01 to 2% by mass of an oil component in which isostearic acid accounts for 34% by mass or more, (b) 0.04 to 1.0% by mass of a specific hydrophilic surfactant, and (C) The liquid cosmetics which became cloudy on the appearance which mix | blended 0.001-0.75 mass% of specific lipophilic surfactant are described, and the compounding quantity of surfactant is suppressed, maintaining white turbidity. It has a refreshing feel and is excellent in long-term stability and vibration stability.
特許文献3には、油性成分を微細に乳化した皮膚外用剤において、(a)常温で液状の高級アルコール及び/又は高級脂肪酸、(b)非イオン性親水性界面活性剤、(c)水溶性二価アルコール及び(d)水を混合してラメラ液晶相を形成し、それを水性溶媒で希釈することにより得られる皮膚外用剤が記載されている。この皮膚外用剤は脂肪滴の50重量%以上を(a)成分が占め、その粒子径から白濁系と考えられるが、製造方法の簡便さ、長期安定性及びべたつかない使用性の向上に特徴を有している。 Patent Document 3 discloses a skin external preparation in which an oily component is finely emulsified: (a) a higher alcohol and / or higher fatty acid that is liquid at normal temperature, (b) a nonionic hydrophilic surfactant, and (c) a water-soluble agent. A topical skin preparation obtained by mixing a dihydric alcohol and (d) water to form a lamellar liquid crystal phase and diluting it with an aqueous solvent is described. In this external preparation for skin, the component (a) accounts for 50% by weight or more of the lipid droplets, and it is considered to be a cloudy system due to its particle size, but it is characterized by easy manufacturing method, long-term stability and non-sticky usability. Have.
上述した特許文献1及び2に記載された化粧料では、常温で液状の分岐飽和脂肪酸、特にイソステアリン酸を油分中に所定量配合することにより、長期安定性及び振動安定性における向上は確認されているが、例えば凍結時あるいは高温での安定性に劣る場合があり、使用感のやわらかさも不十分であった。また、特許文献3に皮膚外用剤は、凍結時あるいは高温での安定性、及び使用感のやわらかさは評価されておらず、例えば二価アルコールをグリセリンに置換した場合(比較例6)、あるいは界面活性剤を置換した場合(比較例5)に所望の特性が得られない等、その処方の幅が限られていた。 In the cosmetics described in Patent Documents 1 and 2 described above, improvement in long-term stability and vibration stability has been confirmed by blending a predetermined amount of a branched saturated fatty acid, particularly isostearic acid, at a normal temperature into the oil. However, for example, the stability at freezing or at a high temperature may be inferior, and the softness of use is insufficient. Patent Document 3 does not evaluate the external preparation for skin when frozen or at a high temperature, and the softness of the feeling of use. For example, when dihydric alcohol is substituted with glycerin (Comparative Example 6), or When the surfactant is substituted (Comparative Example 5), the range of the formulation is limited, such as failure to obtain desired characteristics.
よって本発明は、特に透明から半透明の液状化粧料において、凍結や高温保存といった過酷な条件を経ても透明性(L値)が安定に維持され、べたつきがなくやわらかな使用感を有する液状化粧料を提供することを目的とする。 Therefore, the present invention provides a liquid makeup that is transparent and translucent and has a soft feeling without being sticky and having a stable transparency (L value) even under severe conditions such as freezing and high-temperature storage. The purpose is to provide a fee.
上記課題を解決するために、本発明者等は鋭意検討を重ねた結果、イソステアリルアルコールを油分の60質量%以上を占めるように配合し、特定の親水性界面活性剤と組み合わせることにより、過酷な条件下でも優れた安定性を示し、やわらかな使用感を有する液状化粧料が得られることを見出し、本発明を完成するに至った。 In order to solve the above-mentioned problems, the present inventors have conducted intensive studies, and as a result, blended isostearyl alcohol so as to occupy 60% by mass or more of oil, and combined with a specific hydrophilic surfactant, The present inventors have found that a liquid cosmetic material that exhibits excellent stability even under mild conditions and has a soft feeling of use can be obtained, thereby completing the present invention.
すなわち本発明は、(a)0.01〜3質量%の油分と、(b)ポリオキシエチレン硬化ヒマシ油及びポリオキシエチレンフィトステロールから選択される親水性界面活性剤とを含有し、L値が60以上である透明から半透明の液状化粧料であって、イソステアリルアルコールが前記(a)油分の60質量%以上を占めることを特徴とする化粧料を提供する。 That is, the present invention contains (a) 0.01 to 3% by mass of oil and (b) a hydrophilic surfactant selected from polyoxyethylene hydrogenated castor oil and polyoxyethylene phytosterol, and has an L value. A transparent to translucent liquid cosmetic material having 60 or more, wherein isostearyl alcohol occupies 60% by mass or more of the (a) oil content.
本発明の化粧料は、油分を微粒子化して配合した液状化粧料が有する利点、即ち、嗜好に応じた使用感触と肌改善効果の幅広く実現という利点を有している上、凍結や高温などの過酷な条件下でも安定性を保ち、べたつきがなくやわらかな使用感を得ることができる。 The cosmetics of the present invention have the advantages of liquid cosmetics formulated with finely divided oils, that is, the benefits of wide use feeling and skin improvement effect according to taste, as well as freezing and high temperature, etc. Maintains stability even under harsh conditions, and can provide a soft feeling without stickiness.
本発明の化粧料は、微粒子化した油分を水性媒体中に含む液状化粧料であり、より具体的には、化粧水を代表例とする透明又は半透明の液状化粧料である。化粧水は一般に、水不溶性物質を可溶化して熱力学的に安定化させ外観を透明液状としたもの指すが、本発明における液状化粧料は、前記の透明可溶化型以外にも、マイクロエマルション、リピッドナノスフィア技術を採用した透明から半透明の化粧水、あるいは、化粧水タイプの透明から半透明のエッセンス(美容液)を含む。 The cosmetic of the present invention is a liquid cosmetic containing finely divided oil in an aqueous medium. More specifically, the cosmetic is a transparent or translucent liquid cosmetic containing skin lotion as a representative example. Skin lotion generally refers to a water-insoluble substance solubilized and thermodynamically stabilized to have a transparent liquid appearance. The liquid cosmetic in the present invention is not limited to the above-mentioned transparent solubilized type, but a microemulsion. , Including a transparent to translucent lotion using lipid nanosphere technology, or a lotion type transparent to translucent essence (beauty serum).
本明細書における「透明から半透明」とは、そのL値が60以上のものを意味する。L値とはLab表色系におけるLの値を意味し、例えば、Color−EYE7000(GretagMacbeth社製)等の公知の色差計、又は公知の分光光度計を用いて測定することができる値である。
水性媒体中に分散される油分微粒子の粒径は、化粧料が透明から半透明の外観を有する範囲であれば特に限定されないが、通常は約100nm以下の平均粒径とするのが好ましい。
In the present specification, “transparent to translucent” means that the L value is 60 or more. The L value means the value of L in the Lab color system, and is a value that can be measured using a known color difference meter such as Color-EYE7000 (manufactured by GretagMacbeth) or a known spectrophotometer. .
The particle size of the oil fine particles dispersed in the aqueous medium is not particularly limited as long as the cosmetic has a transparent to translucent appearance, but it is usually preferable to have an average particle size of about 100 nm or less.
本発明の化粧料は、(a)油分及び(b)親水性界面活性剤を必須成分として含有する。
本発明の化粧料における(a)油分は、その60質量%以上をイソステアリルアルコールが占めている。イソステアリルアルコールが占める割合が60質量%未満であると、使用性のやわらかさに欠けるものとなり、凍結時又は高温での安定性も低下する。
The cosmetic of the present invention contains (a) an oil component and (b) a hydrophilic surfactant as essential components.
Isostearyl alcohol accounts for 60 mass% or more of the (a) oil in the cosmetic of the present invention. When the proportion of isostearyl alcohol is less than 60% by mass, the usability is not soft, and the stability at freezing or at high temperature is also lowered.
本発明で使用されるイソステアリルアルコール以外の油分としては、化粧料等に従来から使用されている油分から選択でき、特に限定されるものではない。例えば、油脂類、ロウ類、炭化水素油、高級脂肪酸、高級アルコール、エステル油、シリコーン油、さらには油溶性薬剤等が挙げられる。
具体例を挙げれば、アボガド油、ツバキ油、タートル油、マカデミアナッツ油、トウモロコシ油、ミンク油、オリーブ油、ナタネ油、卵黄油、ゴマ油、パーシック油、小麦胚芽油、サザンカ油、ヒマシ油、アマニ油、サフラワー油、綿実油、エノ油、大豆油、落花生油、茶実油、カヤ油、コメヌカ油、シナギリ油、日本キリ油、ホホバ油、胚芽油、トリイソオクタン酸グリセリン、トリイソパルミチン酸グリセリン、イソパルミチン酸オクチル、イソステアリン酸イソプロピル、イソステアリン酸イソステアリル、イソステアリン酸イソセチル、イソステアリン酸ヘキシル、イソステアリン酸ミリスチル、オクタン酸イソセチル、イソオクタン酸セチル、オクタン酸イソステアリル、イソノナン酸イソデシル、ジメチルオクタン酸オクチルドデシル、ミリスチン酸オレイル、エルカ酸イソステアリル、ステアリン酸イソセチル、ステアリン酸オクチル、パルミチン酸イソステアリル、パルミチン酸イソセチル、パルミチン酸オクチル、ミリスチン酸イソステアリル、ミリスチン酸イソセチル、ミリスチン酸オクチルドデシル、ミリスチン酸デシル、パルミチン酸イソプロピル、ミリスチン酸イソプロピル、トリイソステアリン酸トリメチロールプロパン、ジカプリン酸ネオペンチルグリコール、セバシン酸ジオクチル、12−ステアロイルオキシステアリン酸オクチルドデシル、ステアロイルグルタミン酸ジオクチルドデシル、アジピン酸ジオクチル、リンゴ酸ジイソステアリル、メトキシケイ皮酸オクチル、乳酸オクチルドデシル、乳酸イソステアリル、パラジメチルアミノ安息香酸オクチル、流動パラフィン、スクワラン、イソパラフィン、α−オレフィンオリゴマー、ポリブテン、揮発性環状シリコーン、揮発性ジメチルポリシロキサン、メチルフェニルシリコーン、オレイルアルコール、2−オクチルドデカノール、カカオ脂、ヤシ油、馬脂、硬化ヤシ油、パーム油、牛脂、羊脂、硬化牛脂、パーム核油、豚脂、牛骨脂、モクロウ核油、硬化油、牛脚脂、モクロウ、硬化ヒマシ油、ミツロウ、カンデリラロウ、綿ロウ、カルナウバロウ、ベイベリーロウ、イボタロウ、鯨ロウ、モンタンロウ、ヌカロウ、ラノリン、カポックロウ、酢酸ラノリン、液状ラノリン、サトウキビロウ、ラノリン脂肪酸イソプロピル、ラウリン酸ヘキシル、還元ラノリン、ジョジョバロウ、硬質ラノリン、セラックロウ、コレステロール、フィトステロール、マイクロクリスタリンワックス、ベヘニルアルコール、ステアリルアルコール、セチルアルコール、ベヘニン酸、ステアリン酸、イソステアリン酸、オレイン酸、ミリスチン酸等である。これらは一種を単独でまたは二種以上を組み合わせて用いることができる。
The oil other than isostearyl alcohol used in the present invention can be selected from oils conventionally used in cosmetics and the like, and is not particularly limited. Examples thereof include oils and fats, waxes, hydrocarbon oils, higher fatty acids, higher alcohols, ester oils, silicone oils, and oil-soluble drugs.
Specific examples include avocado oil, camellia oil, turtle oil, macadamia nut oil, corn oil, mink oil, olive oil, rapeseed oil, egg yolk oil, sesame oil, persic oil, wheat germ oil, sasanca oil, castor oil, flaxseed oil, Safflower oil, cottonseed oil, eno oil, soybean oil, peanut oil, tea seed oil, kaya oil, rice bran oil, cinnagari oil, Japanese kiri oil, jojoba oil, germ oil, triisooctanoic acid glycerin, triisopalmitic acid glycerin, iso Octyl palmitate, isopropyl isostearate, isostearyl isostearate, isocetyl isostearate, hexyl isostearate, myristyl isostearate, isocetyl octanoate, cetyl isooctanoate, isostearyl octanoate, isodecyl isononanoate, octyl dimethyloctanoate Syl, oleyl myristate, isostearyl myelate, isocetyl stearate, octyl stearate, isostearyl palmitate, isocetyl palmitate, octyl palmitate, isostearyl myristate, isocetyl myristate, octyldodecyl myristate, decyl myristate, Isopropyl palmitate, isopropyl myristate, trimethylolpropane triisostearate, neopentyl glycol dicaprate, dioctyl sebacate, octyldodecyl 12-stearoyloxystearate, dioctyldecyl stearoylglutamate, dioctyl adipate, diisostearyl malate, methoxy Octyl cinnamate, octyl dodecyl lactate, isostearyl lactate, paradimethylaminobenzoate Octyl acid, liquid paraffin, squalane, isoparaffin, α-olefin oligomer, polybutene, volatile cyclic silicone, volatile dimethylpolysiloxane, methylphenyl silicone, oleyl alcohol, 2-octyldodecanol, cocoa butter, coconut oil, horse fat, Hardened palm oil, palm oil, beef tallow, sheep fat, hardened beef tallow, palm kernel oil, pork tallow, beef bone oil, owl kernel oil, hardened oil, beef leg oil, owl, hardened castor oil, beeswax, candelilla wax, cotton wax, Carnauba wax, bayberry wax, ibota wax, whale wax, montan wax, nuka wax, lanolin, kapok wax, lanolin acetate, liquid lanolin, sugar cane wax, lanolin fatty acid isopropyl, hexyl laurate, reduced lanolin, jojoballow, hard lanolin, shellac wax, cholesterol, Itosuteroru, microcrystalline wax, behenyl alcohol, stearyl alcohol, cetyl alcohol, behenic acid, stearic acid, isostearic acid, oleic acid, myristic acid and the like. These can be used individually by 1 type or in combination of 2 or more types.
本発明の化粧料においては、イソステアリルアルコールが油分の60質量%以上を占めることが必須であり、他の油分の配合量は必然的に油分の40質量%未満となる。従って、上記したような各種油分、例えば、イソステアリン酸等の高級脂肪酸等の各々の配合量は、最大で40質量%、例えば30質量%未満、あるいは20質量%未満、あるいは10質量%未満、あるいは1質量%未満等となる。 In the cosmetic of the present invention, it is essential that isostearyl alcohol occupies 60% by mass or more of the oil component, and the blending amount of other oil components is inevitably less than 40% by mass of the oil component. Therefore, the blending amount of each of the various oils as described above, for example, higher fatty acids such as isostearic acid, is at most 40% by mass, for example, less than 30% by mass, or less than 20% by mass, or less than 10% by mass, or It becomes less than 1 mass%.
本発明の化粧料における油分の配合量は、0.01〜3質量%、好ましくは0.1〜1質量%、より好ましくは0.2〜0.8質量%である。油分の配合量が0.01質量%未満では所定の効果が得られず、3質量%を越えると、それを乳化するための界面活性剤も増加して、べたついた使用感となる傾向がある。 The compounding quantity of the oil in the cosmetics of this invention is 0.01-3 mass%, Preferably it is 0.1-1 mass%, More preferably, it is 0.2-0.8 mass%. When the oil content is less than 0.01% by mass, the predetermined effect cannot be obtained. When the oil content exceeds 3% by mass, the surfactant for emulsifying the oil tends to increase, resulting in a sticky feeling. .
本発明の化粧料における(b)親水性界面活性剤は、ポリオキシエチレン硬化ヒマシ油及びポリオキシエチレンフィトステロールから選択される1種又は2種の混合物である。
ポリオキシエチレン硬化ヒマシ油は、20〜100のエチレンオキサイド単位を持つ硬化ヒマシ油誘導体であり、例えば、POE(40)硬化ヒマシ油、POE(60)硬化ヒマシ油、POE(100)硬化ヒマシ油等が挙げられる。ニッコールHCO(日光ケミカルズ)、EMALEX HC(日本エマルジョン)、ユニオックスHC(日油)等の市販品を使用してもよい。
ポリオキシエチレンフィトステロールは、10〜50のエチレンオキサイド単位を持つフィトステロール誘導体であり、例えばPOE(10)フィトステロール、POE(20)フィトステロール、POE(30)フィトステロール等が挙げられる。ニッコールBPS(日光ケミカルズ)等の市販品を使用することもできる。
The hydrophilic surfactant (b) in the cosmetic of the present invention is one or a mixture of two selected from polyoxyethylene hydrogenated castor oil and polyoxyethylene phytosterol.
Polyoxyethylene hydrogenated castor oil is a hardened castor oil derivative having 20 to 100 ethylene oxide units, such as POE (40) hydrogenated castor oil, POE (60) hydrogenated castor oil, POE (100) hydrogenated castor oil, etc. Is mentioned. Commercial products such as Nikkor HCO (Nikko Chemicals), EMALEX HC (Nihon Emulsion), and UNIOX HC (Nippon Oil) may be used.
Polyoxyethylene phytosterol is a phytosterol derivative having 10 to 50 ethylene oxide units, and examples thereof include POE (10) phytosterol, POE (20) phytosterol, and POE (30) phytosterol. Commercial products such as Nikkor BPS (Nikko Chemicals) can also be used.
本発明の化粧料における(b)親水性界面活性剤の配合量は、好ましくは0.01〜3質量%、より好ましくは0.05〜1質量%、さらに好ましくは0.1〜0.2質量%である。0.01質量%未満であると安定な乳化が困難になり、3質量%を越えて配合するとべたつきを生ずる場合がある。 The amount of the (b) hydrophilic surfactant in the cosmetic of the present invention is preferably 0.01 to 3% by mass, more preferably 0.05 to 1% by mass, and still more preferably 0.1 to 0.2%. % By mass. If it is less than 0.01% by mass, stable emulsification becomes difficult, and if it exceeds 3% by mass, stickiness may occur.
本発明の化粧料は、(c)親油性界面活性剤を更に含有するのが好ましい。親油性界面活性剤を配合することにより特に高温保存時の安定性が更に向上する。
本発明における(c)親油性界面活性剤は、ジイソステアリン酸ポリグリセリル、セスキイソステアリン酸ソルビタン、及びセスキオレイン酸ソルビタンから選択される1種又は2種以上の混合物である。
The cosmetic of the present invention preferably further contains (c) a lipophilic surfactant. By blending a lipophilic surfactant, stability during high temperature storage is further improved.
The (c) lipophilic surfactant in the present invention is one or a mixture of two or more selected from polyglyceryl diisostearate, sorbitan sesquiisostearate, and sorbitan sesquioleate.
ジイソステアリン酸ポリグリセリルは、親油性界面活性剤として作用するジイソステアリン酸ジグリセリル、ジイソステアリン酸トリグリセリル等を含み、例えば、WOGEL−18DV (マツモトファインケミカル)、コスモール42V(日清オイリオ)、EMALEX DISG(日本エマルジョン)、リソレックス PGIS(高級アルコール工業)等の市販品が使用できる。
セスキイソステアリン酸ソルビタンとしては、エステモール182V(日清オイリオ)、EMALEX SPIS−150(日本エマルジョン)、ニッコール SI−15RV(日光ケミカルズ)等、セスキオレイン酸ソルビタンとしては、EMALEX SPO−150(日本エマルジョン)、ニッコール SO−15V(日光ケミカルズ)、NOFABLE SO−852S(日油)、コスモール82(日清オイリオ)等の市販品も好ましく使用される。
Polyglyceryl diisostearate includes diglyceryl diisostearate acting as a lipophilic surfactant, triglyceryl diisostearate, and the like. For example, WOGEL-18DV (Matsumoto Fine Chemical), Cosmol 42V (Nisshin Oillio), EMALEX DISG (Japan Emulsion) Commercial products such as Risolex PGIS (higher alcohol industry) can be used.
Examples of sorbitan sesquiisostearate include esthetic mall 182V (Nisshin Oilio), EMALEX SPIS-150 (Nihon Emulsion), Nikkor SI-15RV (Nikko Chemicals), etc., and sorbitan sesquioleate, EMALEX SPO-150 (Nihon Emulsion) Commercial products such as Nikkor SO-15V (Nikko Chemicals), NOFABLE SO-852S (Nissho), and Cosmol 82 (Nisshin Oilio) are also preferably used.
本発明の化粧料における(c)親油性界面活性剤の配合量は、好ましくは0.01〜2質量%、より好ましくは0.01〜1.5質量%、さらに好ましくは0.05〜1質量%である。 The amount of the (c) lipophilic surfactant in the cosmetic of the present invention is preferably 0.01 to 2% by mass, more preferably 0.01 to 1.5% by mass, and still more preferably 0.05 to 1. % By mass.
また、本発明の化粧料は、塩型薬剤を安定に配合することができる。従って、本発明の化粧料は、(d)塩型薬剤を更に含有するのが好ましい。
本発明における(d)塩型薬剤は、塩を形成可能な水溶性の薬剤を意味し、化粧料等に通常配合されうる水溶性薬剤であれば特に限定されない。L−アスコルビン酸およびその誘導体の塩、トラネキサム酸およびその誘導体の塩、アルコキシサリチル酸およびその誘導体の塩、グルタチオンおよびその誘導体の塩などが好ましい例として挙げられるが、これら例示に限定されるものでない。
Moreover, the cosmetics of this invention can mix | blend a salt type chemical | medical agent stably. Therefore, it is preferable that the cosmetic of the present invention further contains (d) a salt-type drug.
The (d) salt-type drug in the present invention means a water-soluble drug capable of forming a salt, and is not particularly limited as long as it is a water-soluble drug that can be usually blended in cosmetics and the like. Preferable examples include salts of L-ascorbic acid and its derivatives, salts of tranexamic acid and its derivatives, salts of alkoxysalicylic acid and its derivatives, salts of glutathione and its derivatives, but are not limited to these examples.
L−アスコルビン酸は、一般にビタミンCと言われ、強い還元作用により細胞呼吸作用、酵素賦活作用、膠原形成作用を有し、かつメラニン還元作用を有する。L−アスコルビン酸誘導体としては、L−アスコルビン酸モノリン酸エステル、L−アスコルビン酸−2−硫酸エステルなどのL−アスコルビン酸モノエステル類;L−アスコルビン酸トリリン酸エステルなどのL−アスコルビン酸トリエステル類;L−アスコルビン酸2−グルコシドなどのL−アスコルビン酸グルコシド類などが挙げられる。本発明ではL−アスコルビン酸、L−アスコルビン酸リン酸エステル、L−アスコルビン酸−2−硫酸エステル、L−アスコルビン酸2−グルコシドの各塩の形で好適に用いられる。 L-ascorbic acid is generally referred to as vitamin C, and has a cell respiration effect, an enzyme activation effect, a collagen formation action by a strong reduction action, and a melanin reduction action. L-ascorbic acid derivatives include L-ascorbic acid monoesters such as L-ascorbic acid monophosphate and L-ascorbic acid-2-sulfate; L-ascorbic acid triesters such as L-ascorbic acid triphosphate And L-ascorbic acid glucosides such as L-ascorbic acid 2-glucoside. In this invention, it uses suitably in the form of each salt of L-ascorbic acid, L-ascorbic acid phosphate ester, L-ascorbic acid-2-sulfate ester, and L-ascorbic acid 2-glucoside.
トラネキサム酸誘導体としては、トラネキサム酸の二量体、(例えば、塩酸トランス−4−(トランス−アミノメチルシクロヘキサンカルボニル)アミノメチルシクロヘキサンカルボン酸、等)、トラネキサム酸とハイドロキキノンのエステル体(例えば、4−(トランス−アミノメチルシクロヘキサンカルボン酸4’−ヒドロキシフェニルエステル、等)、トラネキサム酸とゲンチシン酸のエステル体(例えば、2−(トランス−4−アミノメチルシクロヘキシルカルボニルオキシ)−5−ヒドロキシ安息香酸、等)、トラネキサム酸のアミド体(例えば、トランス−4−アミノメチルシクロヘキサンカルボン酸メチルアミド、トランス−4−(p−メトキシベンゾイル)アミノメチルシクロヘキサンカルボン酸、トランス−4−グアニジノメチルシクロヘキサンカルボン酸、等)などが挙げられる。本発明ではトラネキサム酸の塩あるいはトラネキサム酸誘導体の塩の形で好適に用いられる。 Examples of the tranexamic acid derivative include a dimer of tranexamic acid (for example, trans-4- (trans-aminomethylcyclohexanecarbonyl) aminomethylcyclohexanecarboxylic acid, etc.), an ester of tranexamic acid and hydroxyquinone (for example, 4- (trans-aminomethylcyclohexanecarboxylic acid 4′-hydroxyphenyl ester, etc.), ester form of tranexamic acid and gentisic acid (for example, 2- (trans-4-aminomethylcyclohexylcarbonyloxy) -5-hydroxybenzoic acid ), Amides of tranexamic acid (for example, trans-4-aminomethylcyclohexanecarboxylic acid methylamide, trans-4- (p-methoxybenzoyl) aminomethylcyclohexanecarboxylic acid, trans-4-guanidi Methylcyclohexane carboxylic acid, etc.) is preferably used in the form of a salt of a salt or tranexamic acid derivative of tranexamic acid in the like. The present invention.
アルコキシサリチル酸は、サリチル酸の3位、4位または5位のいずれかの水素原子がアルコキシ基にて置換されたものであり、置換基であるアルコキシ基は、好ましくはメトキシ基、エトキシ基、プロポキシ基、イソプロポキシ基、ブトキシ基、イソブトキシ基のいずれかであり、さらに好ましくはメトキシ基またはエトキシ基である。具体的に化合物名を例示すれば、3−メトキシサリチル酸、3−エトキシサリチル酸、4−メトキシサリチル酸、4−エトキシサリチル酸、4−プロポキシサリチル酸、4−イソプロポキシサリチル酸、4−ブトキシサリチル酸、5−メトキシサリチル酸、5−エトキシサリチル酸、5−プロポキシサリチル酸などが挙げられる。本発明ではアルコキシサリチル酸およびその誘導体(エステルなど)の各塩の形で好適に用いられる。 Alkoxysalicylic acid is one in which the hydrogen atom at the 3-position, 4-position or 5-position of salicylic acid is substituted with an alkoxy group, and the alkoxy group as the substituent is preferably a methoxy group, an ethoxy group or a propoxy group. , An isopropoxy group, a butoxy group or an isobutoxy group, more preferably a methoxy group or an ethoxy group. Specific examples of compound names include 3-methoxysalicylic acid, 3-ethoxysalicylic acid, 4-methoxysalicylic acid, 4-ethoxysalicylic acid, 4-propoxysalicylic acid, 4-isopropoxysalicylic acid, 4-butoxysalicylic acid, 5-methoxysalicylic acid. , 5-ethoxysalicylic acid, 5-propoxysalicylic acid and the like. In this invention, it uses suitably in the form of each salt of alkoxy salicylic acid and its derivatives (ester etc.).
上記薬剤の塩としては、特に限定されないが、例えば、ナトリウム塩、カリウム塩、カルシウム塩のようなアルカリ金属塩またはアルカリ土類金属塩のほか、アンモニウム塩、アミノ酸塩等の塩が挙げられる。 Although it does not specifically limit as a salt of the said chemical | medical agent, For example, salts, such as ammonium salt and an amino acid salt other than alkali metal salt or alkaline-earth metal salt like sodium salt, potassium salt, calcium salt, are mentioned.
(d)塩型薬剤は1種または2種以上を組み合わせて配合することができ、その配合量は任意である。通常は、液状化粧料全量に対して、0.1〜30.0質量%程度の範囲で配合される。 (D) One or more salt-type drugs can be blended, and the blending amount is arbitrary. Usually, it mix | blends in about 0.1-30.0 mass% with respect to liquid cosmetics whole quantity.
また、本発明においては、上記以外にも、液状化粧料に通常用いられる各種成分を、本発明の効果を阻害しない範囲で適宜配合してもよい。具体例を挙げれば、プロピレングリコール、ジプロピレングリコール、1,3−ブチレングリコール、1,4−ブチレングリコール、ジエチレングリコール、トリエチレングリコール、ポリエチレングリコール等のグリコール類;グリセリン、ジグリセリン、ポリグリセリン等のグリセリン類;ソルビトール、マンニトール、マルチトール、キシリトール、エリスリトール等の糖アルコール類;フルクトース、グルコース、ガラクトース、マルトース、ラクトース、トレハロース等の糖類;タルク、カオリン、雲母、シリカ、ゼオライト等の無機粉末;ポリアミド樹脂粉末(ナイロン粉末)、ポリエチレン粉末、ポリメタクリル酸メチル粉末、ポリスチレン粉末、スチレンとアクリル酸の共重合体樹脂粉末、セルロース粉末等の有機粉末;二酸化チタン、酸化亜鉛等の無機白色顔料;酸化鉄(ベンガラ)等の無機赤色系顔料;黄酸化鉄、黄土等の無機黄色系顔料;黒酸化鉄、カーボンブラック等の黒色系顔料;酸化クロム、水酸化クロム、チタン酸コバルト等の無機緑色系顔料;群青、紺青等の無機青色系顔料;酸化チタンコーテッドマイカ、着色酸化チタンコーテッドマイカ、オキシ塩化ビスマス、魚鱗箔等のパール顔料;アルミニウムパウダー、カッパーパウダー等の金属粉末顔料;赤色201号、赤色202号、赤色204号、赤色205号、赤色220号、赤色226号、赤色228号、赤色405号、橙色203号、橙色204号、黄色205号、黄色401号、及び青色404号等の有機顔料;赤色3号、赤色104号、赤色106号、赤色227号、赤色230号、赤色401号、赤色505号、橙色205号、黄色4号、黄色5号、黄色202号、黄色203号、緑色3号及び青色1号などのジルコニウム、バリウム又はアルミニウムレーキ等の有機顔料;クロロフィル、β−カロチン等の天然色素;アラビアガム、トラガントガム、ガラクタン、グアガム、キャロブガム、カラヤガム、ジェランガム、カラギーナン等の植物系高分子;キサンタンガム、デキストラン、サクシノグルカン、プルラン等の微生物系高分子;コラーゲン、カゼイン、アルブミン、ゼラチン等の動物系高分子;カルボキシメチルデンプン、メチルヒドロキシプロピルデンプン等のデンプン系高分子;メチルセルロース、エチルセルロース、メチルヒドロキシプロピルセルロース、ヒドロキシエチルセルロース、セルロース硫酸ナトリウム、ヒドロキシプロピルセルロース、カルボキシメチルセルロースナトリウム、結晶セルロース等のセルロース系高分子;アルギン酸ナトリウム、アルギン酸プロピレングリコールエステル等のアルギン酸系高分子;ポリビニルアルコール、ポリビニルアセテート、ポリビニルメチルエーテル、ポリビニルピロリドン、ビニルピロリドンとビニルアセテート共重合物、カルボキシビニルポリマー等のビニル系高分子;ポリアクリル酸ナトリウム、ポリエチルアクリレート、ポリアクリル酸アルカノールアミン、アルキルメタクリレートとジメチルアミノエチルメタクリレート共重合物、ポリ2−アクリルアミド−2−メチルプロパンスルホン酸、ポリメタクリロイルオキシトリメチルアンモニウム等のアクリル系高子;ビタミンB6塩酸塩、パントテニルエチルエーテル等のビタミン類;紫外線吸収剤、キレート剤、殺菌剤、消炎剤、防腐剤、植物抽出液、アミノ酸、清涼剤等の薬剤;エタノール、イソプロピルアルコール等の低級アルコール等が含まれる。 Moreover, in this invention, you may mix | blend suitably the various components normally used for liquid cosmetics in the range which does not inhibit the effect of this invention besides the above. Specific examples include glycols such as propylene glycol, dipropylene glycol, 1,3-butylene glycol, 1,4-butylene glycol, diethylene glycol, triethylene glycol, and polyethylene glycol; glycerin such as glycerin, diglycerin, and polyglycerin. Sugar sugars such as sorbitol, mannitol, maltitol, xylitol, erythritol; sugars such as fructose, glucose, galactose, maltose, lactose, trehalose; inorganic powders such as talc, kaolin, mica, silica, zeolite; polyamide resin powder (Nylon powder), polyethylene powder, polymethyl methacrylate powder, polystyrene powder, copolymer resin powder of styrene and acrylic acid, organic powder such as cellulose powder; Inorganic white pigments such as titanium oxide and zinc oxide; inorganic red pigments such as iron oxide (Bengara); inorganic yellow pigments such as yellow iron oxide and ocher; black pigments such as black iron oxide and carbon black; chromium oxide; Inorganic green pigments such as chromium hydroxide and cobalt titanate; inorganic blue pigments such as ultramarine and bitumen; pearl pigments such as titanium oxide coated mica, colored titanium oxide coated mica, bismuth oxychloride, fish scale foil; aluminum powder, copper Metal powder pigments such as powder: Red 201, Red 202, Red 204, Red 205, Red 220, Red 226, Red 228, Red 405, Orange 203, Orange 204, Yellow 205 Organic pigments such as yellow 401 and blue 404; red 3, red 104, red 106, red 227, red 230, Organic pigments such as zirconium, barium or aluminum lakes such as color 401, red 505, orange 205, yellow 4, yellow 5, yellow 202, yellow 203, green 3 and blue 1; chlorophyll, Natural pigments such as β-carotene; plant polymers such as gum arabic, tragacanth gum, galactan, guar gum, carob gum, caraya gum, gellan gum, carrageenan; microbial polymers such as xanthan gum, dextran, succinoglucan, pullulan; collagen, casein Animal polymers such as albumin and gelatin; starch polymers such as carboxymethyl starch and methylhydroxypropyl starch; methylcellulose, ethylcellulose, methylhydroxypropylcellulose, hydroxyethylcellulose, cellulose sulfate Cellulose polymers such as lithium, hydroxypropylcellulose, sodium carboxymethylcellulose, crystalline cellulose; alginic polymers such as sodium alginate and propylene glycol alginate; polyvinyl alcohol, polyvinyl acetate, polyvinyl methyl ether, polyvinyl pyrrolidone, vinyl pyrrolidone and vinyl Vinyl polymers such as acetate copolymer and carboxyvinyl polymer; sodium polyacrylate, polyethyl acrylate, alkanolamine polyacrylate, alkyl methacrylate and dimethylaminoethyl methacrylate copolymer, poly-2-acrylamido-2-methylpropane Acrylic high molecules such as sulfonic acid and polymethacryloyloxytrimethylammonium; Vitamin B6 salt Vitamins such as salt and pantothenyl ethyl ether; UV absorbers, chelating agents, bactericides, anti-inflammatory agents, antiseptics, plant extracts, amino acids, refreshing agents, etc .; lower alcohols such as ethanol and isopropyl alcohol It is.
本発明の透明から半透明の液状化粧料は、スキンケアを目的とした化粧水、美容液等として用いられる他、サンスクリーン基剤、サンタン基剤、洗浄基剤として用いることができる。このうち特に化粧水として用いるのが好ましい。
本発明の化粧料は、化粧水等の液状化粧料に通常用いられる方法に従って製造することができる。具体的には、水溶性成分を水に溶解して水相とし、油分等の水不溶性成分を両親媒性成分(界面活性剤)と混合し、それを水相に添加して攪拌することにより調製される。
The transparent to translucent liquid cosmetic composition of the present invention can be used as a skin lotion, cosmetic liquid and the like for skin care, as well as a sunscreen base, a suntan base, and a cleaning base. Among these, it is particularly preferable to use as a lotion.
The cosmetic of the present invention can be produced according to a method usually used for liquid cosmetics such as lotions. Specifically, by dissolving a water-soluble component in water to form an aqueous phase, mixing a water-insoluble component such as oil with an amphiphilic component (surfactant), adding it to the aqueous phase, and stirring. Prepared.
本発明について以下に実施例を挙げてさらに詳述するが、本発明はこれらの実施例により何ら限定されるものではない。なお、配合量は特記しない限り質量%を意味する。 The present invention will be described in more detail with reference to the following examples, but the present invention is not limited to these examples. The blending amount means mass% unless otherwise specified.
(実施例1〜11及び比較例1〜8)
下記の表1〜表4に示す処方で液状化粧料(化粧水)を調製し、それらの特性を下記の評価方法、評価基準に従って評価した。それらの結果を表に併せて示す。
「使用性の評価方法」
実施例及び比較例の各サンプルを、10名の専門パネルに実際に使用してもらい、使用性(べたつきのなさ、及びやわらかさ)について評価した。下記評価点基準に従って各パネルに5段階官能評価してもらい、その合計点により下記評価基準に基づいて判定した。
「評価点基準」
5:非常に優れている
4:優れている
3:普通
2:劣る
1:非常に劣る
「評価基準」
◎:合計点が40点以上
○:合計点が30〜39点
△:合計点が20〜29点
×:合計点が19点以下
(Examples 1-11 and Comparative Examples 1-8)
Liquid cosmetics (skin lotions) were prepared according to the formulations shown in Tables 1 to 4 below, and their properties were evaluated according to the following evaluation methods and evaluation criteria. The results are also shown in the table.
"Usability evaluation method"
Each sample of the examples and comparative examples was actually used by 10 professional panels and evaluated for usability (non-stickiness and softness). Each panel was subjected to a five-step sensory evaluation according to the following evaluation point criteria, and the total score was determined based on the following evaluation criteria.
“Evaluation criteria”
5: Very good 4: Excellent 3: Normal 2: Inferior 1: Very inferior “Evaluation criteria”
◎: Total score of 40 or more ○: Total score of 30-39 △: Total score of 20-29 ×: Total score of 19 or less
「安定性の評価方法」
各サンプルの安定性を以下の条件で評価した。
・60℃保管品の安定性:60℃に1週間保管後にL値の変動を評価。
・50℃保管品の安定性:50℃に2ヶ月間保管後にL値の変動を評価。
・凍結・融解後の安定性:凍結後、室温にて融解して室温に戻った後にL値の変動を評価。
「評価基準」
○:L値の変動が±3未満
○△:L値の変動が±3以上かつ±4未満
△:L値の変動が±4以上かつ±10未満
×:L値の変動が±10以上
"Stability evaluation method"
The stability of each sample was evaluated under the following conditions.
-Stability of products stored at 60 ° C: Evaluation of L value fluctuation after storage at 60 ° C for 1 week.
-Stability of products stored at 50 ° C: Evaluation of L value fluctuation after storage at 50 ° C for 2 months.
・ Stability after freezing and thawing: After freezing, thawing at room temperature and returning to room temperature, the change in L value was evaluated.
"Evaluation criteria"
○: L value fluctuation is less than ± 3 ○ △: L value fluctuation is ± 3 or more and less than ± 4 Δ: L value fluctuation is ± 4 or more and less than ± 10 ×: L value fluctuation is ± 10 or more
表1〜表4に示した結果から明らかなように、イソステアリルアルコールを油分の60質量%以上を占めるように配合し、特定の親水性界面活性剤と組み合わせて調製した液状化粧料(実施例1〜11)は、極めて良好な使用性(べたつきのなさ、やわらかさ)を有し、50℃又は60℃の高温保存あるいは凍結・溶解という過酷な条件を経ても安定性に優れたものであった。それに対して、イソステアリルアルコールを含まない、又はその配合量が油分の60質量%未満である比較例1〜6及び8では、特にやわらかな使用性が得られず、安定性も格段に劣るものとなった。一方、イソステアリルアルコールが油分の60質量%以上を占めていても、油分の配合量が3質量%を越えている比較例7は、べたつきを生じ、使用性において劣っていた。 As is apparent from the results shown in Tables 1 to 4, liquid cosmetics prepared by combining isostearyl alcohol so as to occupy 60% by mass or more of oil and combining with a specific hydrophilic surfactant (Examples) 1 to 11) have extremely good usability (non-stickiness, softness) and have excellent stability even under severe conditions such as high-temperature storage at 50 ° C. or 60 ° C. or freezing / dissolving. It was. On the other hand, in Comparative Examples 1 to 6 and 8 which do not contain isostearyl alcohol or whose blending amount is less than 60% by mass of the oil component, particularly soft usability is not obtained and the stability is remarkably inferior. It became. On the other hand, even if isostearyl alcohol accounted for 60% by mass or more of the oil component, Comparative Example 7 in which the blending amount of the oil component exceeded 3% by mass produced stickiness and was inferior in usability.
(実施例12〜13及び比較例9)
塩型薬剤(4−メトキシサリチル酸カリウム塩)を配合した下記表5に示す処方で液状化粧料を調製し、前記と同様の評価を行った。結果を表5に併記する。
(Examples 12 to 13 and Comparative Example 9)
A liquid cosmetic was prepared according to the formulation shown in Table 5 below, which was formulated with a salt-type drug (4-methoxysalicylic acid potassium salt), and the same evaluation as described above was performed. The results are also shown in Table 5.
表5に示した結果から、イソステアリルアルコールが油分の60質量%以上を占めるように配合された実施例12及び13では、塩型薬剤である4−メトキシサリチル酸カリウムを安定に配合することができ、やわらかな使用感も維持されるが、イソステアリルアルコールの配合量が所定量に満たない比較例9では、その使用性は劣化し、特に高温保存時の安定性が格段に低下した。 From the results shown in Table 5, in Examples 12 and 13 in which isostearyl alcohol was blended so as to occupy 60% by mass or more of the oil, potassium 4-methoxysalicylate, which is a salt-type drug, could be stably blended. Although a soft feeling of use is maintained, in Comparative Example 9 in which the blending amount of isostearyl alcohol is less than a predetermined amount, the usability is deteriorated, and the stability at high temperature storage is particularly lowered.
実施例14:半透明化粧水
配合成分 配合量(質量%)
エタノール 5
グリセリン 5
ジプロピレングリコール 7
ブチレングリコール 5
エリスリトール 1
キシリトール 1
PEG/PPG−17/4ジメチルエーテル 3
POE(30)フィトステロール 0.14
セスキオレイン酸ソルビタン 0.02
イソステアリルアルコール 0.3
α‐オレフィンオリゴマー 0.2
キサンタンガム 0.1
クエン酸 適量
クエン酸ナトリウム 適量
メタリン酸ナトリウム 適量
フェノキシエタノール 適量
香料 適量
イオン交換水 残余
Example 14: Translucent lotion blending component Blending amount (% by mass)
Ethanol 5
Glycerin 5
Dipropylene glycol 7
Butylene glycol 5
Erythritol 1
Xylitol 1
PEG / PPG-17 / 4 dimethyl ether 3
POE (30) phytosterol 0.14
Sorbitan sesquioleate 0.02
Isostearyl alcohol 0.3
α-Olefin oligomer 0.2
Xanthan gum 0.1
Citric acid Appropriate amount Sodium citrate Appropriate amount Sodium metaphosphate Appropriate amount Phenoxyethanol Appropriate perfume Appropriate amount Ion-exchanged water Residue
製造方法:常法に従って水に水溶性成分を順次溶解し水相を調整した。水不溶性成分は両親媒性成分と混合後に水相に添加した。 Production method: A water phase was prepared by sequentially dissolving water-soluble components in water according to a conventional method. The water-insoluble component was added to the aqueous phase after mixing with the amphiphilic component.
実施例15:半透明化粧水
配合成分 配合量(質量%)
グリセリン 10
ジプロピレングリコール 7
ブチレングリコール 5
POE(10)メチルグルコシド 2
エリスリトール 1
PEG−400 1
PEG/PPG−14/7ジメチルエーテル 1
ポリオキシエチレン硬化ヒマシ油(60EO) 0.16
ジイソステアリン酸ポリグリセリル−2 0.08
イソステアリルアルコール 0.3
ヒドロキシエチルセルロース 0.1
クエン酸 適量
クエン酸ナトリウム 適量
エデト酸2ナトリウム 適量
フェノキシエタノール 適量
香料 適量
イオン交換水 残余
Example 15: Translucent lotion blending component Blending amount (% by mass)
Glycerin 10
Dipropylene glycol 7
Butylene glycol 5
POE (10) methyl glucoside 2
Erythritol 1
PEG-400 1
PEG / PPG-14 / 7 dimethyl ether 1
Polyoxyethylene hydrogenated castor oil (60EO) 0.16
Polyglyceryl-2 diisostearate 0.08
Isostearyl alcohol 0.3
Hydroxyethyl cellulose 0.1
Citric acid appropriate amount sodium citrate appropriate amount edetate disodium appropriate amount phenoxyethanol appropriate amount perfume appropriate amount ion-exchanged water remainder
製造方法:常法に従って水に水溶性成分を順次溶解し水相を調整した。水不溶性成分は両親媒性成分と混合後に水相に添加した。 Production method: A water phase was prepared by sequentially dissolving water-soluble components in water according to a conventional method. The water-insoluble component was added to the aqueous phase after mixing with the amphiphilic component.
実施例16:美白用半透明化粧水
配合成分 配合量(質量%)
エタノール 7
グリセリン 4
ジプロピレングリコール 5
ブチレングリコール 3
POE(10)メチルグルコシド 1
PEG−20 1
PEG/PPG−14/7ジメチルエーテル 1
ポリオキシエチレン硬化ヒマシ油(60EO) 0.16
ジイソステアリン酸ポリグリセリル−2 0.08
イソステアリルアルコール 0.18
イソステアリン酸 0.06
α‐オレフィンオリゴマー 0.06
グリチルリチン酸ジカリウム 0.1
酢酸トコフェロール 0.1
トラネキサム酸 2
オウゴンエキス 0.1
ジオウエキス 0.1
ユキノシタエキス 0.1
オドリコソウエキス 0.1
クエン酸 適量
クエン酸ナトリウム 適量
エデト酸3ナトリウム 適量
フェノキシエタノール 適量
香料 適量
イオン交換水 残余
Example 16: Translucent lotion blending component for whitening Blending amount (% by mass)
Ethanol 7
Glycerin 4
Dipropylene glycol 5
Butylene glycol 3
POE (10) methyl glucoside 1
PEG-20 1
PEG / PPG-14 / 7 dimethyl ether 1
Polyoxyethylene hydrogenated castor oil (60EO) 0.16
Polyglyceryl-2 diisostearate 0.08
Isostearyl alcohol 0.18
Isostearic acid 0.06
α-Olefin oligomer 0.06
Dipotassium glycyrrhizinate 0.1
Tocopherol acetate 0.1
Tranexamic acid 2
Ogon Extract 0.1
Giant extract 0.1
Yukinoshita extract 0.1
Nettle extract 0.1
Citric acid appropriate amount sodium citrate appropriate amount edetate trisodium appropriate amount phenoxyethanol appropriate amount perfume appropriate amount ion-exchanged water remainder
製造方法:常法に従って水に水溶性成分を順次溶解し水相を調整した。水不溶性成分は両親媒性成分と混合後に水相に添加した。 Production method: A water phase was prepared by sequentially dissolving water-soluble components in water according to a conventional method. The water-insoluble component was added to the aqueous phase after mixing with the amphiphilic component.
実施例17:美白用半透明化粧水
配合成分 配合量(質量%)
エタノール 8
グリセリン 3
ジプロピレングリコール 5
ブチレングリコール 3
POE(10)メチルグルコシド 1
PEG−20 1
PEG/PPG−14/7ジメチルエーテル 1
ポリオキシエチレン硬化ヒマシ油(60EO) 0.16
ジイソステアリン酸ポリグリセリル−2 0.08
イソステアリルアルコール 0.18
イソステアリン酸 0.06
α‐オレフィンオリゴマー 0.06
グリチルリチン酸ジカリウム 0.1
アスコルビン酸グルコシド 2
塩酸アルギニン 0.1
水酸化カリウム 0.4
オウゴンエキス 0.1
ジオウエキス 0.1
ユキノシタエキス 0.1
オドリコソウエキス 0.1
クエン酸 適量
クエン酸ナトリウム 適量
エデト酸2ナトリウム 適量
パラベン 適量
香料 適量
イオン交換水 残余
Example 17: Translucent lotion blending component for whitening Blending amount (% by mass)
Ethanol 8
Glycerin 3
Dipropylene glycol 5
Butylene glycol 3
POE (10) methyl glucoside 1
PEG-20 1
PEG / PPG-14 / 7 dimethyl ether 1
Polyoxyethylene hydrogenated castor oil (60EO) 0.16
Polyglyceryl-2 diisostearate 0.08
Isostearyl alcohol 0.18
Isostearic acid 0.06
α-Olefin oligomer 0.06
Dipotassium glycyrrhizinate 0.1
Ascorbic acid glucoside 2
Arginine hydrochloride 0.1
Potassium hydroxide 0.4
Ogon Extract 0.1
Giant extract 0.1
Yukinoshita extract 0.1
Nettle extract 0.1
Citric acid appropriate amount sodium citrate appropriate amount edetate disodium appropriate amount paraben appropriate amount perfume appropriate amount ion-exchange water remainder
製造方法:常法に従って水に水溶性成分を順次溶解し水相を調整した。水不溶性成分は両親媒性成分と混合後に水相に添加した。 Production method: A water phase was prepared by sequentially dissolving water-soluble components in water according to a conventional method. The water-insoluble component was added to the aqueous phase after mixing with the amphiphilic component.
Claims (4)
(b)ポリオキシエチレン硬化ヒマシ油及びポリオキシエチレンフィトステロールから選択される親水性界面活性剤と、
(c)ジイソステアリン酸ポリグリセリル、セスキイソステアリン酸ソルビタン、及びセスキオレイン酸ソルビタンから選択される親油性界面活性剤と
を含有し、L値が60以上である透明から半透明の液状化粧料であって、
イソステアリルアルコールが前記(a)油分の60質量%以上を占めることを特徴とする化粧料。 (A) 0.01-3 mass% oil component,
(B) a hydrophilic surfactant selected from polyoxyethylene hydrogenated castor oil and polyoxyethylene phytosterol ;
(C) a transparent to translucent liquid cosmetic comprising an oleophilic surfactant selected from polyglyceryl diisostearate, sorbitan sesquiisostearate, and sorbitan sesquioleate, and having an L value of 60 or more. Because
Cosmetics characterized in that isostearyl alcohol accounts for 60% by mass or more of the (a) oil content.
Priority Applications (6)
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| JP2011200427A JP5753466B2 (en) | 2011-09-14 | 2011-09-14 | Liquid cosmetics |
| CN201280044322.5A CN103781462B (en) | 2011-09-14 | 2012-08-14 | Liquid cosmetic |
| PCT/JP2012/070673 WO2013038861A1 (en) | 2011-09-14 | 2012-08-14 | Liquid cosmetic material |
| KR1020147009535A KR101589476B1 (en) | 2011-09-14 | 2012-08-14 | Liquid cosmetic material |
| HK14110793.2A HK1197188B (en) | 2011-09-14 | 2012-08-14 | Liquid cosmetic material |
| TW101133182A TWI530298B (en) | 2011-09-14 | 2012-09-11 | Liquid cosmetic |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011200427A JP5753466B2 (en) | 2011-09-14 | 2011-09-14 | Liquid cosmetics |
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| JP2013060398A JP2013060398A (en) | 2013-04-04 |
| JP5753466B2 true JP5753466B2 (en) | 2015-07-22 |
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| JP (1) | JP5753466B2 (en) |
| KR (1) | KR101589476B1 (en) |
| CN (1) | CN103781462B (en) |
| TW (1) | TWI530298B (en) |
| WO (1) | WO2013038861A1 (en) |
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| JP2016013507A (en) * | 2014-07-01 | 2016-01-28 | 株式会社タイホーコーザイ | Oil-in-water type emulsion defoaming agent composition |
| JP6629035B2 (en) * | 2015-10-15 | 2020-01-15 | 日本メナード化粧品株式会社 | Liquid oily lip cosmetic |
| KR102598477B1 (en) | 2016-09-21 | 2023-11-06 | (주)아모레퍼시픽 | Oil-in-water cosmetic composition |
| KR101904155B1 (en) | 2018-06-01 | 2018-10-05 | 주식회사 엘지생활건강 | Nanoemulsion compositions having improved thermal stability |
| JP7162544B2 (en) * | 2019-01-29 | 2022-10-28 | 株式会社 資生堂 | Cloudy cosmetics |
| CN115942871A (en) * | 2020-04-23 | 2023-04-07 | 阿奇英国生物灭杀剂有限公司 | Synergistic preservative/personal care composition with polyglycerides |
| JP7550451B2 (en) * | 2021-04-13 | 2024-09-13 | 株式会社みらい中央研究所 | Translucent cosmetic material with radiance |
| FR3138871A1 (en) * | 2022-08-18 | 2024-02-23 | L'oreal | COMPOSITION INCLUDING SELECTED OIL AND DIOL |
| KR20250012679A (en) * | 2022-07-12 | 2025-01-24 | 로레알 | Cosmetic composition containing selected oils and diol |
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| JPH04160264A (en) | 1990-10-23 | 1992-06-03 | Seiko Epson Corp | Small size gear for analog watch |
| JP2005255667A (en) * | 2004-02-12 | 2005-09-22 | Shiseido Co Ltd | Liquid cosmetic |
| JP5508682B2 (en) * | 2007-07-27 | 2014-06-04 | 株式会社 資生堂 | Oil-in-water emulsion composition and method for producing the same |
| JP2010120857A (en) | 2008-11-17 | 2010-06-03 | Doctor Program Kk | Skin external preparation |
| JP2010173999A (en) * | 2009-02-02 | 2010-08-12 | Shiseido Co Ltd | Liquid cosmetic |
| JP5348784B2 (en) * | 2009-12-28 | 2013-11-20 | 株式会社 資生堂 | Cosmetics |
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| Publication number | Publication date |
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| JP2013060398A (en) | 2013-04-04 |
| CN103781462A (en) | 2014-05-07 |
| TWI530298B (en) | 2016-04-21 |
| KR101589476B1 (en) | 2016-01-28 |
| WO2013038861A1 (en) | 2013-03-21 |
| KR20140069134A (en) | 2014-06-09 |
| TW201317008A (en) | 2013-05-01 |
| CN103781462B (en) | 2016-02-24 |
| HK1197188A1 (en) | 2015-01-09 |
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