JP6534100B2 - Feed additive and feed containing the additive - Google Patents

Description

  The present invention relates to a feed additive which is conveniently obtained using a volcanic foam foam and is added for the purpose of promoting the health of livestock and preventing diseases, and a feed containing the same.

Rearing of livestock was often left undisturbed until the middle of Showa, and was often reared on a spacious area. Starting from the 1940's, the breeding of broilers began, and fattening pigs were also increasingly being wielded to improve productivity. In addition, grazing has become severe from the viewpoint of environmental problems, and it has almost been bred in livestock houses. If the animals are kept secretly, the area of the livestock stalls can be small, and the number of breeding and cleaning operations can be reduced, so production efficiency can be improved and costs can be reduced. In grazing, polluted water from livestock manure and the like often flows into rivers and the like due to rainwater etc. Currently, almost all of them are reared in livestock houses.
However, the stockbreeding of livestock such as broilers and fattening pigs gives the livestock animals a high degree of stress, resulting in lack of exercise and deterioration of hygiene.
In order to improve productivity under such conditions, efforts have been made to clean and disinfect the inside of livestock buildings, to perform temperature control frequently, to make maximum efforts not to apply stress, and to alleviate environmental deterioration. However, even if hygiene, breeding, and environmental management are thoroughly followed, the current situation is that we can never escape from the fight against each disease. For example, diarrhea caused by E. coli, when a piglet is affected, increases the number of days of fattening, which significantly increases the production cost and puts pressure on management. In addition, chicken flu, swine epidemic diarrhea (PED), foot-and-mouth disease, etc. pose a threat not only domestically but worldwide. All of these are diseases involving viruses, and there is currently no effective treatment available.

  In order to prevent the occurrence of the above-mentioned diseases caused by the deterioration of hygiene, feed containing antibiotics and antibacterial growth promoting substances is used, but antibiotics remaining in livestock's excrement inhibit composting, There is also the problem of causing the emergence of resistant bacteria (Non-Patent Document 1). Furthermore, antibiotics and the like can not effectively suppress the occurrence of viral diseases.

  In addition, in the case of rearing in a livestock house, in the case of free-ranging, minerals naturally consumed from the soil naturally run short in order to be reared on concrete. A particularly striking example is that sows that have finished parturition and have been weaned can not walk. When this sow is released to the soil playground for 7 to 10 days, almost all of the cows stand up and start walking, so each farm mixes minerals with feed.

At present, various mineral additives such as minerals are blended in feed. As the inorganic additive, for example, powder of zeolite, shellfish fossil, scallop, etc. is used.
However, since these additives supplement minerals and are not expected to have antibacterial effects, they can not suppress the growth of bacteria such as Escherichia coli and viruses.

As with all livestock production, it is important how to maintain postnatal health to prevent the delay of growth due to death or disease of livestock and to improve productivity. For example, in pig farming, it is no exaggeration to say that if you can maintain good health for 60 days after birth, you will hardly get sick after that.
Therefore, while being able to supplement the mineral which tends to run short to livestock kept in livestock housing, it is possible to effectively prevent diseases caused by bacteria and viruses, especially in young and young livestock. Is required.

Takahashi Toshio et al .; Journal of Infectious Diseases Vol. 80, No. 3, pp. 185-195 2006

  Therefore, it is an object of the present invention to provide a feed additive which is effective for mineral replacement, has an antibacterial action and an antiviral action, can prevent livestock diseases, and can dramatically improve fattening efficiency. Do.

  As a result of intensive studies to solve the above-mentioned problems, the present inventor has found that a composition containing a volcanic effervescent foam particle and an inorganic alkaline substance in a specific weight ratio has antibacterial activity and antiviral activity, The present invention has been found to be able to prevent diseases caused by bacteria and viruses when fed to livestock, and to also function as a source of minerals necessary for livestock.

That is, the present invention is as follows.
[1] (A) volcano product foam and (B) inorganic alkaline substance, the weight ratio of (A) to (B) ([A]: [B]) is 1: 0.01 to 1: 0 . 5. A feed additive comprising the composition contained to be 5.
[2] The additive for feed according to [1], wherein the volcanic product foam is at least one selected from the group consisting of shirasu foam, obsidian foam and pearlite foam.
[3] The inorganic alkaline substance is sodium hydroxide, potassium hydroxide, magnesium hydroxide, calcium hydroxide, sodium silicate, potassium silicate, magnesium silicate, calcium silicate, sodium carbonate, sodium carbonate, potassium carbonate, magnesium carbonate and carbonate The feed additive according to [1] or [2], which is at least one selected from the group consisting of calcium.
[4] The feed additive according to any one of [1] to [3], wherein the composition containing (A) the volcanic product foam and (B) the inorganic alkaline substance is solidified by carbon dioxide .
[5] The feed additive according to any one of [1] to [4], which is powdery or granular.
[6] The feed additive according to [5], having an average particle size of 50 μm to 1,000 μm.
[7] The feed additive according to any one of [1] to [6], which is added to feed for breeding pig or fattening pig.
[8] A feed comprising the feed additive according to any one of [1] to [6].
[9] The feed according to [8], which is for breeding pigs or fattening pigs.
[10] [8] A method of raising a livestock, which comprises feeding the feed according to [8] to the livestock.
[11] The breeding method according to [10], wherein the domestic animal is a pig.

The feed additive of the present invention is excellent in antibacterial activity and antiviral activity against bacteria such as E. coli, and by taking it into livestock, it can prevent diseases caused by bacteria and viruses, and it is possible to use minerals necessary for livestock. It is also useful as a source.
In addition, the feed additive of the present invention can be easily produced, and can be provided at low cost because it uses a volcanic spray foam.

  The feed additive of the present invention comprises (A) volcanic foam foam and (B) inorganic alkaline substance in a weight ratio of (A) to (B) ([A]: [B]) of 1: 0. It contains a composition contained so as to be 01 to 1: 0.5 (hereinafter sometimes referred to as “the composition for an additive of the present invention”).

The (A) volcanic substance foam used in the composition for additives according to the present invention heats fine particles or powder of volcanic substance to about 700 ° C. to about 1,100 ° C., preferably about 850 ° C. to about 1,000 ° C. Can be obtained by foaming.
The volcanic ejecta used for preparation of the said volcanic ejecta foam is a substance which erupted on the surface at the time of the volcanic activity, and volcanic ash such as volcanic ash and volcanic debris etc. are included. For the purpose of the present invention, shirasu, pumice, bora soil, obsidian, pearlite and the like are preferably used as volcanic products. Among them, shirasu, obsidian and pearlite are more preferable.

  In the present invention, as the (A) volcanic product foam, one or two or more types can be selected and used from the above-mentioned volcanic product foam. (Shirath balloon), obsidian foam (perlite) and perlite foam (perlite) are preferable, and shiras foam is more preferable in that the strength for maintaining the porosity of the additive composition is excellent.

The average particle diameter of the foam of the volcanic spray product (A) used in the composition for additives of the present invention is usually 5 μm to 300 μm for shirasu foam, 50 μm to 3,000 μm for obsidian foam, 50 μm to 50 μm for pearlite foam It is 3,000 μm, preferably 30 μm to 200 μm for Shirasu foam, 50 μm to 300 μm for obsidian foam, and 50 μm to 300 μm for pearlite foam.
In addition, the said average particle diameter is the value which measured and calculated by the sieving method mentioned later.

As the inorganic alkaline substance (B) used in the composition for additives according to the present invention, hydroxides of alkali metals such as sodium hydroxide and potassium hydroxide, and water of alkaline earth metals such as magnesium hydroxide and calcium hydroxide Oxides, alkali metal salts of silicic acid such as sodium silicate, potassium silicate etc., alkaline earth metal salts of silicic acid such as magnesium silicate, calcium silicate etc, alkali metal salts of carbonate such as sodium carbonate, potassium carbonate etc, Examples thereof include alkaline earth metal salts of carbonic acid such as magnesium carbonate and calcium carbonate, etc. From these, one kind may be selected and used alone or in combination of two or more kinds.
For the purpose of the present invention, an alkali metal salt of silicic acid is preferably used as the (B) inorganic alkaline substance, and sodium silicate and potassium silicate are more preferably used.
In addition, (B) inorganic alkaline substance may be used in the state of powder, and may be used as aqueous solution.

The additive composition of the present invention comprises (A) a volcanic foam foam and (B) an inorganic alkaline substance in a weight ratio of (A) to (B) ([A]: [B]) of 1: 0. .01 to 1: 0.5 to be contained. The weight ratio ([A]: [B]) of (A) to (B) is preferably 1: 0.02 to 1: 0.4, and 1: 0.02 to 1: 0.3. It is more preferable that
When the weight ratio ([B] / [A]) of the (B) inorganic alkaline substance to the (A) volcanic foam foam is smaller than 0.01, the antibacterial activity and the antiviral activity are unfavorably reduced. On the other hand, when the weight ratio ([B] / [A]) of (B) inorganic alkaline substance to (A) volcanic foam foam is larger than 0.5, the basicity of the composition for additives becomes strong, Feeding livestock may cause loss of appetite and digestive tract problems. In addition, the cost increases, which is not preferable in terms of economy.

To the additive composition of the present invention, adsorbents such as activated carbon, charcoal, bamboo charcoal and the like can be further added as long as the features of the present invention are not impaired.
The additive composition of the present invention may be introduced into a container, a bag or the like, sealed, injected with carbon dioxide gas, and solidified.

The additive composition of the present invention can be used as a feed additive as it is or by adding other additives.
For the feed additive of the present invention, additives which are usually used as feed additives can be used without particular limitation as long as the characteristics of the present invention are not impaired.
As feed additives, for example, additives for preventing deterioration of feed quality, additives for supplementation of nutritional components of feed and other active ingredients, and effective utilization of nutritional components contained in feed Feed additives such as feed additives specified by the Minister of Agriculture, Forestry and Fisheries based on the provisions of Article 2, Paragraph 3 of the Act on Ensuring Food Safety and Improvement of Quality.
One or two or more of the above-described feed additives can be used in the feed additive of the present invention.

  Additives to prevent deterioration of feed quality include antioxidants such as dibutyl hydroxytoluene and butyl hydroxyanisole; fungicides such as propionic acid and sodium propionate; sodium alginate, sodium carboxymethylcellulose, polyacrylic acid Binders such as sodium; glycerin fatty acid esters, sucrose fatty acid esters, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, emulsifiers such as polyoxyethylene glycerin fatty acid esters, and regulators such as formic acid.

  Additives for supplementation of nutritional components and other active ingredients of feed include amino acids such as aminoacetic acid, DL-alanine, sodium L-glutamate; L-ascorbic acid, ergocalciferol, thiamine hydrochloride, cholecalciferol, vitamins A powder, vitamin D powder, vitamins such as riboflavin; minerals such as potassium chloride, iron citrate, calcium gluconate; pigments such as astaxanthin and canthaxanthin.

  Additives for promoting the effective utilization of nutritional components contained in feed include synthetic antibacterial agents such as molanter citrate and decokinate; antibiotics such as zinc acitracin, chlortetracycline and tyrosin phosphate; flavoring agents; Flavoring agents such as sodium saccharin; Enzymes such as amylase, alkaline protease, cellulase, lipase, etc .; Probiotic agents such as Enterococcus faecalis, Bacillus subtilis, Bifidobacterium pseudolongum etc. Etc.

The feed additive of the present invention may be in the form of solid, such as granular, powder, granular, gel, etc., or semi-solid, such as paste, but it is in granular or powdered form. Is preferred.
The average particle size of the feed additive in the form of particles or powder is usually 50 μm to 1,000 μm, preferably 100 μm to 500 μm, and more preferably 150 μm to 150 μm, as a value measured and calculated by a sieving method described later. It is 300 μm.

  The content of the composition for the above-mentioned additive in the additive for feed of the present invention is preferably 1% by weight to 100% by weight, and 3% by weight to 100% by weight with respect to the total amount of the additive for feed Is more preferred.

Further, in the present invention, the above-described feed additive of the present invention can be mixed with an excipient substance for feed or a diluted substance to make a feed.
As the excipient and diluent for feed, the excipient and diluent generally used for feed preparation can be used without limitation as long as the features of the present invention are not impaired. For example, components of feed and feed additives The ones listed in 3 of the Ministerial Ordinance Appendix 2 regarding standards etc. may be mentioned.
For the feed of the present invention, one or two or more can be selected and used from the above-mentioned excipient and diluent and the like.

  As excipients and diluents for feed, polysaccharides such as gum arabic, carrageenan, agar, xanthan gum, chitosan, cellulose, locust bean gum; monosaccharides or disaccharides such as glucose, lactose, maltose, sucrose, etc .; glycerin, sorbitol, Sugar alcohols such as D-mannitol; Proteins such as albumin, casein, gluten, gelatin, etc .; Cereal flours such as wheat flour, wheat flour, soy flour, corn flour etc. Yeasts such as Torula yeast, baker's yeast, brewer's yeast; Fats and oils, fats and oils such as animal fats and oils; clay minerals such as kaolin, zeolite, talc, vermiculite and bentonite; diatomaceous earth, hydrous silicon dioxide, metasilicic acid, silicic acid such as light anhydrous silicic acid, anhydrous silicic acid; light liquid paraffin, fluid Hydrocarbons such as paraffin; Wax such as carnauba wax etc. That.

  The content of the additive for feed in the feed of the present invention varies depending on the type of livestock, adult livestock, distinction of offspring, sex, growth stage, etc., but as the content of the composition for the above additive relative to the total amount of feed, In the case of an animal feed, it is preferably 0.05% by weight to 10% by weight, more preferably 0.1% by weight to 7% by weight, and in the case of an animal feed, 0.01% by weight It is preferably 10% by weight, and more preferably 0.03% by weight to 7% by weight.

  The additive for feed of the present invention is prepared by mixing (A) volcanic foam foam and (B) inorganic alkaline substance in the above weight ratio, and optionally adding and mixing other additives such as feed additives After the preparation, it can be prepared by drying, pulverizing, granulating, granulating etc., if necessary.

  The mixing of the (A) volcanic foam foam and (B) the inorganic alkaline substance or the other additive components can be carried out by a general mixing method used for the mixing of powders and particles, and a horizontal cylindrical mixer Various mixers such as V-type mixer, double conical mixer, swing rotary mixer, single-axis ribbon mixer, double-axis paddle mixer, rotary working mixer, conical screw mixer, etc. It carries out using a mixing stirrer etc.

Grinding of the above mixture can be carried out by a common grinding method, and either dry grinding or wet grinding can be used depending on the state of the (B) inorganic alkaline substance at the time of mixing. That is, when (B) inorganic alkaline substance is mixed in a solid state, dry grinding is preferably adopted, and when mixed in the state of an aqueous solution, wet grinding is preferably adopted.
Dry grinding includes jet milling and mechanochemical grinding, and wet grinding includes colloid milling.

Granulation of the mixture can be carried out by a general granulation method, and either dry granulation or wet granulation can be used depending on the state of the (B) inorganic alkaline substance at the time of mixing. That is, dry granulation is preferably employed when (B) inorganic alkaline substance is mixed in a solid state, and wet granulation is preferably employed when mixing in the state of an aqueous solution.
As dry granulation, slug method, roller compactor method etc. may be mentioned, and as wet granulation, stirring mixing granulation method, spray drying granulation method, fluidized bed granulation method, rolling granulation method, rolling flow method Layer granulation method, extrusion granulation method and the like can be mentioned.

  A general sizing method can also be adopted for the sizing of the above mixture. As such a sizing method, grinding, sizing with classification function, crushing, wet continuous sizing, rotary centrifugal crushing, high speed or low speed rotation, spherical sizing, etc. It can be mentioned.

  Drying of the above mixture is preferably carried out by natural drying such as air drying or sun drying.

In the above preparation method of the additive for feed of the present invention, (A) a volcanic foam foam and (B) an inorganic alkaline substance and, if necessary, other additive components are mixed, and if necessary, dried, crushed and granulated. After carrying out, etc., it can be put into a container made of plastic etc., a bag, etc. and sealed, and it can be solidified by injecting and reacting carbon dioxide gas.
In particular, when an alkali metal salt of silicic acid such as sodium silicate or potassium silicate is used in the form of an aqueous solution as (B) an inorganic alkaline substance, a mixture of (A) a volcanic product foam is carbonated By reacting with gas and solidifying, it can be uniformly mixed with the above-mentioned feed additives, and the dispersibility in feed is also improved, which is preferable.

  Further, the feed of the present invention can be prepared by adding an excipient substance for feed or a dilution substance to the above-described additive for feed as required, and mixing, granulating, etc. in the same manner as described above.

  The feed additive of the present invention or the feed of the present invention is a domestic animal, for example, mammals raised for meat such as cows, pigs, sheep, goats and rabbits; Meats such as ducks, chickens, geese, turkeys and quails Or birds reared for collecting eggs; companion animals such as dogs, cats, hamsters, guinea pigs and chipmunk; feed additives or feeds for mammals reared for labor such as alpaca, horses, mules, camels and donkeys However, it is preferably used as a feed additive or feed for livestock for meat such as cattle, pigs and chickens, and is particularly suitable as a feed additive or feed for pigs such as breeding pig and fattening pig .

  Moreover, the additive for feed of the present invention or the feed of the present invention can be suitably used in any of adult livestock, female livestock in the parturition and lactation, and offspring in the weaning to fattening stages, bacteria and viruses It can be more suitably used in parturition and lactation females and weaning offspring highly in need of preventing diseases caused by

The present invention also provides a method of feeding livestock with the feed to which the feed additive of the present invention has been added, and rearing the livestock.
In the breeding method of the present invention, it is preferable to select the form of the feed additive to be added to the feed depending on the type of livestock to be bred, the growth stage and the like. For example, it is preferable to use a granular feed additive for adult breeding such as breeding stock, and to use a powdery or granular feed additive for fattening period live stock.

  Although the feed amount of the feed additive of the present invention varies depending on the type and sex of the livestock to be fed, the growth stage, etc., for example, in the case of a sow during the parturition period or lactation period, the additive composition of the present invention Usually, 5 g to 70 g, preferably 10 g to 50 g, is fed per day as weight, and in the case of piglets in the weaning period to fattening period (fertile pig), the weight per composition of the additive composition of the present invention is usually per day 1 g to 30 g, preferably 5 g to 20 g are fed.

The composition for additives according to the present invention, as described later, contains calcium, phosphorus, iron and the like in addition to silicon dioxide and aluminum oxide etc. which are main components of the volcanic foam, and has antibacterial activity against bacteria and antiviral It shows activity.
Therefore, the feed additive of the present invention containing the additive composition of the present invention functions as a source of mineral which tends to be deficient for livestock reared in a barn, and also has antibacterial and antiviral activity. Thus, it is possible to prevent the occurrence of bacterial diseases such as diarrhea caused by E. coli and salmonellosis, and viral diseases such as foot-and-mouth disease, avian influenza and PED.

  Next, the present invention will be more specifically described by way of examples.

Measurement Method of Average Particle Size The measurement of the average particle size of the composition of (A) volcanic foam described in the specification and the additive composition of the present invention was performed by the following method (sieving method).
Five to ten standard sieves were mounted on an electromagnetic sieve shaker (manufactured by As One Corporation), and the sample was classified by sieve shaking to determine the weight ratio of each particle size classification. That is, the standard sieves were stacked one on top of the large sieve one, 20 g of the sample was placed on the upper stage and shaken for 15 minutes, and the weight of the sample remaining on each sieve was measured to determine the particle size distribution.
Next, for each sieved sample, the ratio (wt%) to the total amount of sample is calculated, and the ratio (wt%) for each sieve is added sequentially from the top, and the sum of the weight ratio of the samples is Assuming that the total value (% by weight) before exceeding 50% by weight is [d] and the above total value (% by weight) after exceeding 50% by weight is [e], the total proportion of the sample weight is 50% by weight The under value (μm or mm) of the particle size class not exceeding is taken as [a]. Then, a section including a particle size having a total sample weight ratio exceeding 50% by weight is identified, and the over value (μm or mm) of the particle size section is [b], the under value (μm or mm) is [c ], The weight average particle diameter was calculated | required from following formula (I).
Average particle size (μm or mm) = a-[(bc) × {(50-d) / e}] (I)

[Example 1] Additive for feed: Shirasu foam ("Shirasu balloon": average particle diameter = 40 μm, manufactured by Toyowa Nao Co., Ltd.) in a mixing and stirring machine ("Mortar mixer" manufactured by Tokai Machinery Co., Ltd.) 1,000 g Then, 100 g of water glass (“Soda Silica No. 3”, manufactured by Nippon Chemical Industrial Co., Ltd.) is mixed and stirred while being sprayed with a sprayer, put in a plastic bag and sealed, and 30 g of carbon dioxide gas is injected It was made to react and the composition for additives (average particle diameter = 100 micrometers) was obtained, and it was set as the additive for feed.

[Example 2] Feed additive Additive Mixing mixer ("Mortar mixer", manufactured by Tokai Kikai Seisakusho Co., Ltd.) Shirasu foam ("Shirasu balloon": average particle diameter = 150 μm, manufactured by Toyowa Nao Co., Ltd.) 1,000 g Then, an aqueous solution of potassium silicate (silicon dioxide (SiO ₂ ) concentration = 27 wt% to 29 wt%, potassium oxide (K ₂ O) concentration = 21 wt% to 23 wt%, manufactured by Nippon Chemical Industrial Co., Ltd.) Mix and stir 100g while spraying with a sprayer, put in a plastic bag and seal, inject 30g of carbon dioxide gas and make it react to obtain a composition for additive (average particle diameter = 300μm), add it as an additive for feed did.

The results of component analysis of the additive composition obtained in Example 2 are shown in Table 1.
The component analysis was entrusted to the Kagoshima Industrial Technology Center, and was performed by a fluorescent X-ray analysis method (instrument used: “fluorescent X-ray analyzer RIX 3000”, manufactured by Rigaku Corporation, calibration curve method). In addition, the ignition loss shown in Table 1 is a gravimetric analysis method (calculated from a decrease in weight when the sample is ignited at 1,000 ° C. for 1 hour in an electric muffle furnace (manufactured by Ito Seisakusho Co., Ltd.)) It measured by.

As shown in Table 1, the additive composition obtained in Example 2 contains various types of minerals including calcium and phosphorus which are known to cause leg weakness in pigs when lacking. contains.
Thus, the feed additive of Example 2 is expected to function as a mineral source.

Test Example 1 Evaluation of Antibacterial Activity The feed additive of Example 2 was evaluated for antibacterial activity against E. coli as follows.
(1) Evaluation method of antibacterial activity (i) E. coli (Escherichia coli NBRC 12734) was used as a test microbe.
(Ii) The test bacterium is inoculated into lecithin / polysorbate 80 / soybean / casein / digest (SCDLP) broth medium (manufactured by Eiken Chemical Co., Ltd.) and cultured at 35 ± 1 ° C., and the culture solution is approximately 10 ⁷ cells / mL. The solution was diluted with sterile saline so as to be a stock solution of bacteria.
(Iii) 600 mL of sterile physiological saline was placed in a 1,000 mL glass beaker, and 1 mL of the above-mentioned stock solution was added to make the number of bacteria per mL 10 ⁴ or so. 50 g of a feed additive was immersed to prepare a test solution.
On the other hand, 600 mL of sterile physiological saline was put in a 1,000 mL stoppered medium bottle, and 1 mL of the above-mentioned stock solution was added to make the number of bacteria per 1 mL 10 ⁴ or so.
(Iv) The above-mentioned test solution and control solution were measured by the mixed culture method at the time of preparation and the number of viable bacteria after being allowed to stand at room temperature for 15, 30 and 60 minutes. Culturing was performed at 35 ± 1 ° C. for 24 hours using a standard agar medium (manufactured by Eiken Chemical Co., Ltd.).
(2) Evaluation results The evaluation results are shown in Table 2 below.

  In Table 2, E. coli in the control solution did not decrease at all even after 60 minutes, while in the test solution in which the feed additive of Example 2 of the present invention was soaked, E. coli decreased with time. After 60 minutes, it decreased to about 1 / 1,000 at the time of preparation, and it was found that the feed additive of Example 2 had antibacterial activity against E. coli.

[Test Example 2] Pig breeding test The feed additive obtained in Example 2 was used to carry out pig breeding test.
The additive for feed of Example 2 is added to 10 sows per day for every 5 cows from May 2013 to October 2013 at Nagatoku Pig Farm (Kagoshima Prefecture), It was fed from 7 days before parturition until weaning. After the lactation, the sows were transferred from the distribution stable to the sows. A total of 25 sows were the subjects of this breeding test. In addition, 30 piglets were added to 5 g of feed per animal per day, and fed from weaning to shipment to conduct a breeding test, and the breeding condition was observed. Sawdust was used as bedding for this test.
The test results are shown in Table 3.

As shown in Table 3, in the case of sows (25 in total), the occurrence of difficulty in walking due to leg paralysis was not observed when transferring from a distribution stable to sows. Out of piglets (total piglet number = 271) which sows (total 25 cows) gave birth to, 10 died (6 pressure death: 4 dead death) by the breeding test. For 30 piglets, none were piglets that died. The average fattening days until shipment was approximately six months as usual.
In addition, no outbreak of PED was found in sows and piglets subjected to the breeding test.

[Example 3] Additive for feed Add 100 kg of Shirasu foam ("Shirasu balloon": average particle diameter = 70 μm, Toyokazu Nao Co., Ltd.) to a mixing and stirring machine ("Mortar mixer", manufactured by Tokai Machinery Co., Ltd.) Next, 30 kg of 21 wt% to 23 wt% aqueous potassium silicate solution (manufactured by Nippon Chemical Industrial Co., Ltd.) is added and mixed, put into a plastic bag and sealed, and then 300 g of carbon dioxide gas is injected to react An additive composition (average particle diameter = 150 μm) was obtained and used as an additive for feed.

  10 g of the composition for an additive obtained in Example 3 was put in 50 mL of distilled water, stirred at 30 ° C., and after 1 hour, the pH was measured with a pen type pH meter (manufactured by Sato Meter Co., Ltd.), The pH was 12.2, and the composition for the additive showed strong basicity.

[Test Example 3] Pig breeding test The feed additive obtained in Example 3 was used to carry out pig breeding test.
Add the feed additive of Example 3 to 10 sows at 10 g a day for each pig from July 2013 to November 2013 at A pig farm in Narita City, Chiba Prefecture , We were fed until weaning from 7 days before parturition. After the lactation, the sows were transferred from the distribution stable to the sows. A total of 50 sows were the subjects of this breeding test. In addition, 50 piglets were added to 5 g of feed per pig per day, fed from weaning to shipping, and conducted a breeding test, and the breeding condition was observed. Sawdust was used as bedding for this test.
The test results are shown in Table 4.

As shown in Table 4, in 2 of the sows (total of 50), the occurrence of difficulty in walking due to leg paralysis was observed when transferring from a distribution stable to sows. For piglets, three died during the fattening period (21 to 90 days after birth), but the average number of days for fattening before shipment was approximately 6 months as usual.
In addition, no outbreak of PED was found in sows and piglets subjected to the breeding test.

[Test Example 4] Pig breeding test The feed additive obtained in Example 3 was used to carry out pig breeding test.
Additive for feed of Example 3 is added to 10 pig feed a day for every 5 cows from June 2013 to November 2013 at No. B pig farm in Shibushi city, Kagoshima , We were fed until weaning from 7 days before parturition. After the lactation, the sows were transferred from the distribution stable to the sows. A total of 25 sows were the subjects of this breeding test. In addition, 30 piglets were added to 5 g of feed per animal per day, and fed from weaning to shipment to conduct a breeding test, and the breeding condition was observed. Sawdust was used as bedding for this test.
The test results are shown in Table 5.

As shown in Table 5, in one of the sows (25 in total), the occurrence of difficulty in walking due to leg paralysis was observed when transferring from the distribution stable to the sows. As for piglets, one pig died before shipping, but the average number of days for fattening was usually about 6 months.
In addition, no outbreak of PED was found in sows and piglets subjected to the breeding test.

As described in detail above, the present invention is excellent in antibacterial activity and antiviral activity against bacteria such as Escherichia coli, can prevent diseases caused by bacteria and viruses, and is also useful as a source of minerals necessary for livestock. Feed additives and feeds can be provided.
Further, according to the present invention, it is possible to provide a method for rearing livestock which can prevent livestock diseases and dramatically improve the fattening efficiency.

Claims (11)

  The weight ratio ([A]: [B]) of (A) to (B) is set to 1: 0.01 to 1: 0.5 for (A) volcanic product foam and (B) inorganic alkaline substance A feed additive comprising the composition to be contained as follows.   The feed additive according to claim 1, wherein the volcanic spray foam is at least one selected from the group consisting of shirasu foam, obsidian foam and pearlite foam.   The inorganic alkaline substance consists of sodium hydroxide, potassium hydroxide, magnesium hydroxide, calcium hydroxide, sodium silicate, potassium silicate, magnesium silicate, calcium silicate, sodium carbonate, potassium carbonate, potassium carbonate, magnesium carbonate and calcium carbonate The feed additive according to claim 1 or 2, which is at least one selected from the group. Inorganic alkaline material is an aqueous solution of an alkali metal salt of silicic acid, (A) volcanic ejecta foam and (B) a composition containing an inorganic alkaline substance, Ru composition der the state of being solidified by carbon dioxide The feed additive according to any one of claims 1 to 3.   The feed additive according to any one of claims 1 to 4, which is powdery or granular.   The additive for feed according to claim 5, wherein the average particle size is 50 m to 1,000 m.   The feed additive according to any one of claims 1 to 6, which is added to feed for breeding pig or fattening pig.   A feed comprising the additive for feed according to any one of claims 1 to 6.   The feed according to claim 8, which is for breeding pigs or fattening pigs.   A method of rearing livestock, wherein the livestock is fed with the feed according to claim 8 and bred.   The breeding method according to claim 10, wherein the livestock is a pig.