JP7425657B2 - drug administration equipment - Google Patents

Description

FIELD OF THE INVENTION The present invention relates to drug administration devices.

A syringe (a syringe with a needle) is used to administer medicine to patients. BACKGROUND ART As a method for storing a medicinal solution to be administered to a patient in a syringe, for example, there is a method of sucking out the medicinal solution from an ampoule or a vial in which the medicinal solution is stored. An ampoule is a container that is filled with a drug solution and then sealed by melting the end of the container with heat. When using the drug solution, the neck of the container is broken, a syringe needle is inserted through the broken part, and the drug solution is sucked out. Is required. A vial is a container (bottle) containing a drug solution with a rubber stopper, and when using the drug solution, it is necessary to insert a needle into the rubber stopper and suck out the drug solution.
On the other hand, there is a prefilled syringe, which is stored in a syringe filled with a drug solution in advance. With a prefilled syringe, there is no need to suck out the drug solution from the container in which it is stored before administering the drug solution. However, some prefilled syringes do not have injection needles attached to them, and it is necessary to attach the injection needle when using them.

US Pat. No. 5,300,303 discloses a drug injection device that provides an automatic mechanism for inserting a needle into a drug cartridge and that reduces manual handling of the needle by the user prior to injection. Patent Document 1 includes: a drug cartridge holder fixed to a main body and configured to hold a drug cartridge; a needle carrier supporting a needle and movable in an axial direction relative to the main body; a rotatable cap at the distal end of the device including a first prestressing spring coupled to the carrier, the cap being such that rotational movement thereof releases the first prestressing spring, thereby causing the needle to The carrier is arranged to move axially toward the proximal end of the device.

Special table 2018-535042 publication

However, with the drug injection device of Patent Document 1, there is a risk that the user may misjudge the puncture depth of the needle during injection. This is because as the needle (needle carrier) moves in the axial direction relative to the main body, the positional relationship between the main body and the needle, which constitutes the outermost part of the device, changes before and after inserting the needle into the drug cartridge. . When administering drug solutions by injection, there is an appropriate puncture depth depending on the drug solution and purpose (intradermal injection, subcutaneous injection, intramuscular injection, etc.); if the puncture depth is not correct, the expected drug effect may not be obtained. There is sex.
SUMMARY OF THE INVENTION Accordingly, the present invention provides a drug administration device that is easy to prepare immediately before administering the drug and can quickly administer the drug at an appropriate puncture depth.

The following will achieve the above objectives:
(1) A hollow double-ended needle having a tip needle portion and a rear needle portion, a prefilled syringe, and a cylindrical case that houses the prefilled syringe so that its tip side faces the rear needle portion of the double-ended needle. A drug administration device comprising: a drug administration device; and a storage body for storing the drug administration device,
The cylindrical case has a side opening at the rear end, stores the double-ended needle in such a way that it is immovable and the tip portion including the distal needle portion protrudes, and the prefilled syringe is housed in the cylindrical case. is stored so as to be movable in the direction of the double-ended needle,
The prefilled syringe includes an outer cylinder having an outer surface protrusion at its rear end, a sealing member that seals the tip of the outer cylinder and allows the rear end needle part of the double-ended needle to pass through, and the outer cylinder. A gasket member capable of sliding in a cylinder in a liquid-tight state, and a gasket pressing member whose rear part protrudes from the cylindrical case,
The storage body is capable of storing the drug administration device and includes a storage main body portion having an opening, and a lid portion that can be attached to the opening of the storage main body portion,
The drug administration tool includes a biasing member that contacts the outer cylinder and biases the prefilled syringe in the direction of the double-ended needle,
The storage body is provided on the inner surface of the storage main body or the lid, removably enters the side opening of the cylindrical case, comes into contact with the front surface of the outer surface protrusion, and holds the prefilled syringe. comprising a stopper portion that restricts movement of the double-ended needle in the direction of the double-ended needle;
The storage main body includes a rectangular main body plate, two opposing side plates that stand up from both longitudinal sides of the main body plate, and an upper plate that stands up from one short side of the main body plate. and an opposing opening that faces the main body plate, and a lower opening that faces the upper plate, and the lid includes a base plate that can be attached to the opposing opening of the storage main body; a lower plate portion that can be attached to the lower opening of the storage body, and the drug administration device is housed in the storage body such that the gasket pressing member is located inside the lower part of the storage body. , furthermore, the stopper part is provided in the storage body, and further,
The biasing member is configured to cause the sealing member of the prefilled syringe to be pierced by the rear end needle portion of the double-ended needle after the drug administration tool is detached from the storage main body portion or the lid portion having the stopper portion. A drug administration device that presses the prefilled syringe so that it becomes open.

(2) The double-ended needle includes a needle tube having the tip needle portion and the rear needle portion, a hub attached to an intermediate portion of the needle tube, a rear end attached to the hub, and a tip closed, The drug administration device according to (1) above, comprising a double-ended needle cap that encloses the tip needle portion.
(3) The storage body is described in ( 2 ) above, wherein the storage body is provided with a cap holding portion for holding the double-ended needle cap on the upper inner surface of the main body plate portion of the storage main body portion or the inner surface of the upper plate portion. drug administration equipment.
The following also achieves the above objectives.
(4) A hollow double-ended needle having a tip end needle portion and a rear end needle portion, a prefilled syringe, and a cylindrical case that houses the prefilled syringe so that its tip side faces the rear end needle portion of the double ended needle. A drug administration device comprising: a drug administration device; and a storage body for storing the drug administration device,
The cylindrical case has a side opening at the rear end, stores the double-ended needle in such a way that it is immovable and the tip portion including the distal needle portion protrudes, and the prefilled syringe is housed in the cylindrical case. is stored so as to be movable in the direction of the double-ended needle,
The prefilled syringe includes an outer cylinder having an outer surface protrusion at its rear end, a sealing member that seals the tip of the outer cylinder and allows the rear end needle part of the double-ended needle to pass through, and the outer cylinder. A gasket member capable of sliding in a cylinder in a liquid-tight state, and a gasket pressing member whose rear part protrudes from the cylindrical case,
The storage body is capable of storing the drug administration device and includes a storage main body portion having an opening, and a lid portion that can be attached to the opening of the storage main body portion,
The drug administration tool includes a biasing member that contacts the outer cylinder and biases the prefilled syringe in the direction of the double-ended needle,
The storage body is provided on the inner surface of the storage main body or the lid, removably enters the side opening of the cylindrical case, comes into contact with the front surface of the outer surface protrusion, and holds the prefilled syringe. comprising a stopper portion that restricts movement of the double-ended needle in the direction of the double-ended needle;
The storage main body includes a rectangular main body plate, two opposing side plate parts that stand up from both longitudinal sides of the main body plate, an upper plate that stands up from both lateral sides of the main body plate, and The drug administration device includes a lower plate portion and an opposing opening facing the main body plate portion, the lid portion includes a base plate portion that can be attached to the opposing opening of the storage main body portion, and the drug administration device The pressing member is housed in the housing so as to be located inside a lower part of the housing, and the stopper portion is provided on the housing, and further,
The biasing member is configured to cause the sealing member of the prefilled syringe to be pierced by the rear end needle portion of the double-ended needle after the drug administration tool is detached from the storage main body portion or the lid portion having the stopper portion. A drug administration device that presses the prefilled syringe so that it becomes open.
(5) The double-ended needle includes a needle tube having the tip needle portion and the rear needle portion, a hub attached to an intermediate portion of the needle tube, a rear end attached to the hub, and a tip closed. The drug administration device according to (4) above, comprising a double-ended needle cap that encloses the tip needle portion.
(6) The drug administration device according to ( 5 ) above, wherein the storage body includes a cap holding portion that protrudes inward from the upper inner surface of the lid portion and holds the double-ended needle cap.
(7) The double-ended needle includes a needle tube having the tip needle portion and the rear needle portion, a hub attached to an intermediate portion of the needle tube, a rear end attached to the hub, and a tip closed, The drug administration device includes a double-ended needle cap that encloses the tip needle portion, and the drug administration device includes a cap connecting member that includes a removable cylindrical case mounting portion and a connecting portion with the double-ended needle cap. The drug administration device according to any one of 1) to ( 6 ).
(8) The stopper portion includes a base portion, two extending portions extending forward from the base portion and facing each other, and a main body of the outer cylinder formed between the two extending portions and the base portion. The cylindrical case includes a notch portion, and the cylindrical case includes an engaging portion with the two extension portions, and when the stopper portion is attached to the cylindrical case, the base portion according to any one of (1) to (7) above, wherein the cylindrical case is engaged with the side opening of the cylindrical case, and the tips of the two extending portions are engaged with the engaging portion of the cylindrical case. drug administration equipment.
(9) The double-ended needle includes a needle tube having the tip needle portion and the rear needle portion, a hub attached to an intermediate portion of the needle tube, one end attached to the hub, and the rear end closed. and an elastic sleeve that envelops the rear end needle, the elastic sleeve being pressed in the direction of the hub to enable penetration by the rear end needle. 8) The drug administration device according to any one of 8).

(10) The cylindrical case includes two side openings facing each other, and the stopper portion includes a base, two extending portions extending forward from the base and facing each other, and the two extending portions facing each other. and a notch for passing through the main body of the outer cylinder formed between the stopper part and the base part, and when the stopper part is attached to the drug administration device, the base part The drug administration according to any one of (1) to ( 9 ) above, which engages with the side opening, and the tip ends of the two extensions engage with the other side opening. utensils.
(11) The cylindrical case is arranged such that after the stopper part is detached from the drug administration device and the sealing member of the prefilled syringe is pierced by the rear end needle part of the double-ended needle, The drug administration device according to any one of (1) to (10) above, further comprising an abutment portion that abuts the distal end surface of the outer surface protrusion of the prefilled syringe to restrict movement.
(12) The cylindrical case includes a guide portion that protrudes inward from the inner surface of the cylindrical case and guides sliding of the prefilled syringe at a position corresponding to the cylindrical body of the stored prefilled syringe. The drug administration device according to any one of (1) to (11) above.
(13) The tip of the biasing member contacts the rear surface of the outer surface protrusion of the prefilled syringe, the rear end contacts the end of the biasing member storage portion of the cylindrical case, and the biasing member The drug administration device according to any one of (1) to (12) above, which is a compressed coil spring through which the gasket pressing member passes.
(14) The gasket pressing member includes a pressing operation part at the base end, and after the stopper part is removed, the sealing member of the prefilled syringe is pierced by the rear end needle part of the double-ended needle. The drug administration device according to any one of (1) to (13) above, wherein the base end portion including the pressing operation portion protrudes from the cylindrical case in this state.
(15) The drug administration device is removably attached to the side of the gasket pressing member, and has a distal end spaced apart from the rear end of the cylindrical case, and when the gasket pressing member moves forward, The drug administration device according to any one of (1) to (14) above, comprising a gasket pressing member movement distance regulating member whose distal end portion can come into contact with the rear end of the cylindrical case.
(16) The drug administration device is attached to the distal end of the cylindrical case, is slidable in the distal direction, and is configured to cover the distal end needle of the double-ended needle protruding from the cylindrical case. The drug administration device according to any one of (1) to (15) above, comprising a cylindrical member.
(17) The drug administration device includes a cylindrical member attached to the distal end of the cylindrical case and for enclosing the distal end needle of the double-ended needle that protrudes from the cylindrical case, and the cylindrical member. the drug administration device according to any one of (1) to (15) above, wherein the cylindrical member is slidable rearward when pressed. .

The drug administration device of the present invention includes a hollow double-ended needle having a tip end needle portion and a rear end needle portion, a prefilled syringe, and a cylindrical case that houses the prefilled syringe so that its tip side faces the rear end needle portion of the double ended needle. and a storage body that houses the drug administration tool. The cylindrical case has a side opening at the rear end, stores the double-ended needle in such a way that it is immovable and the distal end including the distal needle part protrudes, and the prefilled syringe is placed in the direction of the double-ended needle within the cylindrical case. Store it in a movable manner. A prefilled syringe has an outer cylinder with an outer protrusion at the rear end, a sealing member that seals the tip of the outer cylinder and allows the rear end needle of the double-ended needle to penetrate, and a liquid-tight interior inside the outer cylinder. The gasket member is provided with a gasket member that is slidable in this state, and a gasket pressing member whose rear portion protrudes from the cylindrical case. The storage body is capable of storing a drug administration device and includes a storage main body portion having an opening, and a lid portion that can be attached to the opening of the storage main body portion. The drug administration device includes a biasing member that contacts the outer cylinder and biases the prefilled syringe in the direction of the double-ended needle, and the storage body is provided on the inner surface of the storage body or the lid, and the storage body is provided with a side opening of the cylindrical case. A stopper part is provided which removably enters into the part, comes into contact with the front surface of the outer surface protrusion part, and restricts movement of the prefilled syringe in the direction of the double-ended needle. The biasing member presses the prefilled syringe so that the sealing member of the prefilled syringe is pierced by the rear end needle portion of the double-ended needle after the drug administration tool is removed from the storage main body portion or the lid portion having the stopper portion. It has become something to do.

In this drug administration device, the stopper portion is detached from the drug administration device by taking the drug administration device out of the storage body and separating it. Then, the prefilled syringe in the drug administration device is pressed by the biasing member and moves toward the double-ended needle, and the sealing member of the prefilled syringe is pierced by the rear end needle part of the double-ended needle, and the two are connected. . Therefore, the preparation of the drug administration device for administering a drug (making the communication needle communicate with the cylindrical body and making it possible to administer the drug from the puncture needle) can be performed extremely easily and quickly.
Further, the double-ended needle is immovably housed in the cylindrical case, and a distal end portion of the double-ended needle including the distal needle portion protrudes a predetermined length from the distal end of the cylindrical case member. Therefore, the positional relationship between the tip needle and the tip of the cylindrical case does not change throughout preparation for administration, so the preset puncture depth (projection length of the puncture needle) is maintained, and the puncture needle is moved to the predetermined depth. In other words, the drug can be administered at a predetermined puncture depth.

FIG. 1 is a front view of one embodiment of the drug administration device of the present invention. FIG. 2 is a perspective view of the drug administration device shown in FIG. 1 with the storage body removed. FIG. 3 is an explanatory diagram of the constituent members of the drug administration device used in the drug administration device shown in FIG. FIG. 4 is a longitudinal sectional view of the drug administration device shown in FIG. 1. FIG. 5 is a cross-sectional view taken along line AA in FIG. 4. FIG. 6 is a front view of the cylindrical case used in the drug administration device shown in FIG. 1 in an exploded state. FIG. 7 is a bottom view of the cylindrical case shown in FIG. 6 in an exploded state. FIG. 8 is an inner view of the constituent members of the cylindrical case shown in FIG. 6. FIG. 9 is a front view of the lid used in the drug administration device shown in FIG. 1. 10 is a left side view of the lid shown in FIG. 9. FIG. FIG. 11 is a perspective view of the lid shown in FIG. 9. FIG. 12 is a front view of the storage main body used in the drug administration device shown in FIG. 1. FIG. 13 is a perspective view of the storage main body shown in FIG. 12. FIG. 14 is a perspective view of the storage main body shown in FIG. 12. FIG. 15 is a front view of the drug administration device shown in FIG. 1 with the storage body removed. FIG. 16 is an explanatory diagram for explaining the action of the drug administration device of the present invention. FIG. 17 is a longitudinal sectional view of a drug administration device used in the drug administration device of FIG. 16. FIG. 18 is a sectional view taken along line BB in FIG. 17. FIG. 19 is a sectional view of a drug administration device used in a drug administration device according to another embodiment of the present invention. FIG. 20 is a cross-sectional view of a drug administration device according to another embodiment of the present invention. FIG. 21 is an explanatory diagram for explaining the action of the drug administration device of the embodiment shown in FIG. 20. FIG. 22 is an explanatory diagram for explaining the action of the drug administration device of the embodiment shown in FIG. 20. FIG. 23 is a longitudinal sectional view of a drug administration device according to another embodiment of the present invention. FIG. 24 is a front view of a drug administration device according to another embodiment of the present invention. FIG. 25 is an inner view (right side view) of the storage main body used in the drug administration device of the embodiment shown in FIG. 24. FIG. 26 is a sectional view taken along the line CC in FIG. 25. FIG. 27 is an explanatory diagram for explaining the action of the drug administration device of the embodiment shown in FIG. 24. FIG. 28 is an explanatory diagram for explaining the action of the drug administration device of the embodiment shown in FIG. 24. FIG. 29 is an explanatory diagram for explaining the action of the drug administration device of the embodiment shown in FIG. 24. FIG. 30 is a partially enlarged longitudinal cross-sectional view of a storage main body used in a drug administration device according to another embodiment of the present invention. FIG. 31 is a front view of a drug administration device used in a drug administration device according to another embodiment of the present invention. FIG. 32 is a front view of the gasket pressing member movement distance regulating member used in the drug administration device shown in FIG. 31. FIG. 33 is a right side view of the gasket pressing member movement distance regulating member shown in FIG. 32. FIG. 34 is a plan view of the gasket pressing member movement distance regulating member shown in FIG. 32. FIG. 35 is a sectional view taken along line DD in FIG. 33. FIG. 36 is a front view of a drug administration device used in a drug administration device according to another embodiment of the present invention. FIG. 37 is a right side view of the gasket pressing member movement distance regulating member used in the drug administration device shown in FIG. 36. FIG. 38 is a bottom view of the gasket pressing member movement distance regulating member used in the drug administration tool shown in FIG. 37. FIG. 39 is a front view of a drug administration device used in a drug administration device according to another embodiment of the present invention. FIG. 40 is a front view of a drug administration device used in a drug administration device according to another embodiment of the present invention. FIG. 41 is an explanatory diagram for explaining the action of the drug administration tool shown in FIG. 40. FIG. 42 is a front view of a drug administration device used in a drug administration device according to another embodiment of the present invention. FIG. 43 is a front view of a drug administration device according to another embodiment of the present invention. FIG. 44 is a right side view of the drug administration device shown in FIG. 43.

The drug administration device of the present invention will be explained using an embodiment shown in the drawings.
The drug administration device 1 of the present invention includes a hollow double-ended needle 3 having a tip needle part (injection needle part) 31a and a rear end needle part (communicating needle part) 31b, a prefilled syringe 2, and a double-ended needle 3. The device includes a cylindrical case 4 that accommodates the prefilled syringe 2 so that its tip side faces the rear end needle portion 31b, a drug administration device 10, and a storage body 5 that accommodates the drug administration device 10.
The cylindrical case 4 has side openings 43a and 43b at its rear end, accommodates the double-ended needle 3 in such a way that it is immovable and the distal end including the distal needle portion 31a protrudes, and the prefilled syringe 2 is housed in a cylindrical shape. The double-ended needle is housed in a case 4 so as to be movable in three directions.

The prefilled syringe 2 includes an outer cylinder 21 having an outer surface protrusion 26 at the rear end, and a sealing member 24 that seals the tip of the outer cylinder 21 and allows the rear end needle part 31b of the double-ended needle 3 to penetrate. , a gasket 22 that can slide inside the outer cylinder 21 in a liquid-tight state, and a gasket pressing member 23 whose rear portion protrudes from the cylindrical case 4.
The storage body 5 is capable of storing the drug administration device 10 and includes a storage main body 6 having a side opening, and a lid 7 that can be attached to the side opening of the storage main body 6. The drug administration device 10 includes a biasing member 11 that contacts the outer cylinder 21 and biases the prefilled syringe 2 in the direction of the double-ended needle 3 . The storage body 5 is provided on the inner surface of the storage main body 6 or the lid 7, removably enters side openings 43a and 43b at the rear end of the cylindrical case 4, and is connected to the front surface of the outer surface protrusion 26. A stopper portion 50 is provided which abuts against and restricts movement of the prefilled syringe 2 in the direction of the double-ended needle 3. The biasing member 11 is configured such that after the drug administration device 10 is detached from the storage main body 6 or the lid 7 having the stopper portion 50, the sealing member 24 of the prefilled syringe 2 is pierced by the rear end needle portion 31b of the double-ended needle 3. The prefilled syringe 2 is pressed so that it is in the open state.

The drug administration device 1 of the embodiment shown in the drawings consists of a drug administration device 10 and a storage body 5 that houses the device.
As shown in FIGS. 1 to 5, the drug administration device 10 includes a prefilled syringe 2, a double-ended needle 3, a cylindrical case 4, and a biasing member 11.
The storage body 5 includes a storage main body part 6 and a lid part 7 that can be attached to a side opening of the storage main body part 6, and a stopper part 50 is provided on either of them.

As shown in FIGS. 3 and 4, the prefilled syringe 2 includes an outer cylinder 21, a sealing member (seal cap) 24 attached to the nozzle portion of the outer cylinder 21, and a sealing member (seal cap) 24 that is slidably housed within the outer cylinder. The gasket 22 includes a gasket 22 and a gasket pressing member 23 attached to the gasket 22.
The outer cylinder 21 is a cylindrical body made of a transparent or translucent material, preferably a material with low oxygen permeability and water vapor permeability. The outer cylinder 21 includes an outer cylinder main body, a nozzle part 21a provided on the front end side of the outer cylinder main body, and an outer surface protrusion 26 provided on the rear end side of the outer cylinder main body. As shown in FIGS. 3 and 4, the outer surface protrusion 26 is preferably a flat annular protrusion that is formed to protrude in the vertical direction from the entire circumference of the rear end of the outer cylinder main body. In this embodiment, the outer surface protrusion 26 includes opposing widened portions as shown in FIG.

The nozzle portion 21a is located at the tip of the outer cylinder 21, and is provided with an opening at the tip for discharging the chemical solution, etc. inside the outer cylinder, and is formed to taper in diameter toward the tip. The nozzle portion 21a includes a sealing member mounting portion.
Examples of materials for forming the outer cylinder 21 include polypropylene, polyethylene, polystyrene, polyamide, polycarbonate, polyvinyl chloride, poly-(4-methylpentene-1), acrylic resin, acrylonitrile-butadiene-styrene copolymer, and polyethylene terephthalate. Among them, resins such as polypropylene and cyclic polyolefin are preferred because they are easy to mold and have heat resistance.

As shown in FIGS. 3 and 4, the sealing member 24 includes a cylindrical sealing member body and a sealing member 27 housed within the sealing member body. The sealing member 24 includes a nozzle housing portion and a sealing member side outer cylinder mounting portion 24a. In this embodiment, the cylindrical sealing member main body is a cylindrical member that is open at one end and the other end, and has a tapered side opening 24b on the distal end side for attaching the rear end needle 31b. We are prepared. A seal member 27 is housed behind this side opening 24b. One end of the seal cap is closed by the seal member 27.

The seal member 27 is for liquid-tightly sealing the tip opening of the nozzle portion. The nozzle portion 21a is liquid-tightly sealed by the abutment of the nozzle portion tip opening against the sealing member 27. Further, the seal member 27 is made of an elastic material that can be pierced by the rear end needle portion 31b.
Examples of the material for forming the seal member 27 include natural rubber, isoprene rubber, butadiene rubber, fluorine rubber, synthetic rubber such as silicone rubber, styrene elastomer such as SBS elastomer and SEBS elastomer, and ethylene-α-olefin copolymer. It is preferable to use a thermoplastic elastomer such as a polyolefin elastomer.

Examples of materials for forming the sealing member include polypropylene, polyethylene, polystyrene, polyamide, polycarbonate, polyvinyl chloride, poly-(4-methylpentene-1), acrylic resin, acrylonitrile-butadiene-styrene copolymer, and polyethylene terephthalate. Among them, resins such as polypropylene and cyclic polyolefin are preferred because they are easy to mold and have heat resistance.

As shown in FIG. 4, the gasket 22 includes a main body extending with approximately the same outer diameter and a plurality of annular ribs provided on the main body, and these ribs are in liquid-tight contact with the inner surface of the outer cylinder 21. .
Materials for forming the gasket 22 include elastic rubber (for example, butyl rubber, latex rubber, silicone rubber, etc.), synthetic resin (for example, styrene elastomer such as SBS elastomer and SEBS elastomer, ethylene-α olefin copolymer elastomer, etc.). It is preferable to use olefin elastomers (such as olefin elastomers).

The drug administration device 1 of this embodiment includes a gasket pressing member 23 whose rear portion protrudes from the cylindrical case 4. The drug administration device 1 of this embodiment includes a gasket pressing member 23 that can be attached to a gasket member 22 and whose rear portion protrudes from the cylindrical case when attached. Note that the gasket pressing portion may be integrated with the gasket or may be fixed to the gasket member.
Note that the gasket pressing member 23 may be attached after the drug administration device 10 is assembled. In this embodiment, the gasket 22 is provided with a recess that extends inward from its rear end, and this recess has a female thread shape and is formed on the outer surface of a protrusion formed at the tip of the gasket pressing member 23. It can be screwed into the male threaded part. By screwing the two together, the gasket pressing member 23 does not separate from the gasket 22. The above-mentioned types of gaskets and gasket pressing members can be installed after the drug administration device 10 is assembled.

The gasket pressing member 23 has a cylindrical protrusion at its tip, and a male thread is formed on the outer surface of the protrusion. Further, the gasket pressing member 23 includes a main body portion having a cross-shaped cross section and extending in the axial direction, a pressing disk portion provided at the rear end portion, and a rib provided midway through the main body portion.

The prefilled syringe 2 is filled with a drug (medicinal solution) 25 . Drugs (medicinal solutions) 25 include epinephrine injection preparations (vasoconstrictors) that are anti-anaphylactic shock drugs, antiarrhythmic agents (e.g., lidocaine), anticholinergic agents (e.g., atropine), and anticonvulsants (e.g., diazepam). Possible emergency drugs such as

As shown in FIGS. 3 and 4, the double-ended needle 3 includes a needle tube 31 having a tip end needle portion 31a and a rear end needle portion 31b, a hub 32 attached to the intermediate portion of the needle tube 31, and one end attached to the hub 32. an elastic sleeve 33 that is attached to the hub 32, has its rear end closed, and covers the rear end needle portion 31b; and a double-ended needle cap 34 that has its rear end attached to the hub 32, has its tip closed, and covers the tip needle portion 31a. It is equipped with
Preferably, the drug administration device 1 of the present invention includes a cap that encloses the tip end portion of the double-ended needle 3. In this embodiment, the double-ended needle cap 34 constitutes a cap that encloses the tip needle portion 31a. Note that the cap may be one that is attached to the tip of the cylindrical case 4 and covers the tip needle portion 31a of the double-ended needle 3.
The elastic sleeve 33 is elastically deformed by being pressed in the direction of the hub 32 and can be pierced by the rear end needle portion 31b, and the rear end needle portion 31b protrudes by piercing the sleeve 33. .

The double-ended needle 3 includes a hub 32 near the middle of the needle tube 31 (on the rear end needle portion side from the center), through which the needle tube 31 passes. The double-ended needle 3 is attached to the double-ended needle attachment part 47 of the cylindrical case 4 at the hub 32 portion, with axial movement and rotation thereof being restricted. When the double-ended needle 3 is attached to the cylindrical case 4, it protrudes by a predetermined length in the distal direction from the distal end opening 40 of the cylindrical case 4, as shown in FIG. The hub 32 includes an outer surface protrusion 32a that is accommodated in the recess 47a of the double-ended needle attachment part 47 of the cylindrical case 4, and an annular protrusion 32b that engages with the rear end surface of the rear rib recess 47b of the double-ended needle attachment part 47. ing.

A double-ended needle cap 34 for protecting the tip needle portion 31a of the needle tube 31 is detachably attached to the double-ended needle 3. The cap 34 of this embodiment is made of a transparent material or a semi-transparent material, so that the protrusion of the needle tube 31 including the tip needle portion 31a can be visually recognized when the cap 34 is attached to the hub 32. . As the transparent material and semi-transparent material forming the cap 34, polyolefins such as polyethylene and polypropylene, polycarbonate, polystyrene, etc. can be suitably used.

In the double-ended needle 3, an elastic sleeve 33 is attached to the rear end needle part side (rear end part) of the hub 32, and covers the rear end needle part 31b of the needle tube 31. This elastic sleeve 33 is folded into a bellows shape between the hub 32 and the prefilled syringe when the prefilled syringe is inserted into the sealing member. The elastic sleeve 33 may be made of synthetic rubber such as natural rubber, isoprene rubber, butadiene rubber, fluororubber, or silicone rubber, styrene elastomer such as SBS elastomer or SEBS elastomer, or polyolefin elastomer such as ethylene-α-olefin copolymer. It is preferable to use a thermoplastic elastomer or the like.

As shown in FIGS. 1 to 8, the cylindrical case 4 is formed by a connected body of a first case member 41 and a second case member 41, and has an elliptical cylindrical shape.
The first case member 41 and the second case member 42 are semi-cylindrical members, and have a plurality of protrusions 49a and a recess 49b on the inner peripheral edge that serves as the abutting part, as shown in FIG. , by engaging the two, they form a connected body.

The cylindrical case 4 has an elliptical cylindrical shape that can accommodate the outer surface protrusion 26 of the prefilled syringe 2. The cylindrical case 4 includes a double-ended needle storage section and a prefilled syringe storage section inside, and a double-ended needle mounting section 47 that protrudes inward from the inner surface, contacts the outer surface of the outer cylinder 21 of the prefilled syringe 2, and has a prefilled syringe storage section. Guide parts 14a and 14b are provided to guide the sliding movement of the syringe 2. The guide parts 14a and 14b are formed to protrude inward from the inner surface of the cylindrical case 4 at a position corresponding to the cylindrical body of the stored prefilled syringe 2, and their inner shape matches the outer shape of the prefilled syringe 2. It is preferable that the size is slightly larger than that of the actual size.
The cylindrical case 4 includes an engagement portion with a stopper portion 50, which will be described later. In this embodiment, the engagement portion of the cylindrical case with the stopper portion 50 is formed by two side openings (through openings) 43a and 43b formed to face each other. Note that the engaging part with the stopper part 50 may have only one side opening and a recessed part provided at a position facing the side opening and capable of engaging with the stopper part (one end part); A side opening is provided, and on the inner surface of the cylindrical case facing it and slightly toward the distal end, an inner rib is provided that can be engaged with the stopper part (one end) and does not interfere with the movement of the prefilled syringe. It's okay.

The cylindrical case 4 has a first storage part 45 that stores the outer surface protrusion 26 of the prefilled syringe, the biasing member 11 in a compressed state, and the stopper part 50 when the prefilled syringe is locked by the stopper part 50. , after the stopper portion 50 is detached and the prefilled syringe moves forward, a second storage portion 46 is provided that stores the outer surface protrusion 26 of the prefilled syringe. Further, the second storage portion stores the extended tip end portion of the biasing member.

The cylindrical case 4 also allows the outer surface of the prefilled syringe 2 to protrude after the stopper portion 50 is removed and the sealing member 24 of the prefilled syringe 2 is pierced by the rear end needle portion 31b of the double-ended needle 3. It is provided with an abutting portion 46a that abuts against the distal end surface of the portion 26 to restrict movement. In this embodiment, the movement restricting abutment portion 46a is formed by the distal end surface of the second storage portion 46.

Further, as shown in FIG. 4, the cylindrical case 4 includes two opposing slit-shaped side openings 43a and 43b provided on both sides of the rear end. A stopper portion 50 is inserted so as to pass through the side openings 43a, 43b. The stopper portion 50 is removable. The rear surface of the stopper portion 50 comes into contact with the front surface of the outer surface protrusion 26 of the prefilled syringe 2 to restrict forward movement of the prefilled syringe 2.

The cylindrical case 4 preferably has transparency or translucency that allows the double-ended needle 3 and prefilled syringe 2 housed therein to be visually recognized. Materials for forming the cylindrical case 4 include transparent or translucent resins such as polypropylene, polyethylene, polystyrene, polyamide, polycarbonate, polyvinyl chloride, poly(4-methylpentene-1), acrylic resin, Examples include various resins such as acrylonitrile-butadiene-styrene copolymers, polyesters such as polyethylene terephthalate, and cyclic polyolefins.

Further, as shown in FIG. 4, the biasing member 11 housed in the first storage portion of the cylindrical case 4 is connected to the rear end portion 48 of the cylindrical case 4 and the rear surface of the outer surface protrusion 26 of the prefilled syringe 2. It is in a compressed state depending on the time. In this embodiment, a coil spring is used as the biasing member 11, and the gasket pressing member 23 of the prefilled syringe 2 passes through the biasing member 11. Further, in this embodiment, the rear end portion of the biasing member 11 is housed and fixed within an annular recess provided at the rear end portion of the cylindrical case 4.

In the embodiment shown in FIGS. 1 to 5, the storage body 5 includes a storage main body part 6 and a lid part 7 that can be attached to a side opening of the storage main body part 6, and a stopper part 50 is attached to the lid part 7. It is provided.
In this embodiment, as shown in FIGS. 12 to 14, the storage main body 6 of the storage body 5 includes a rectangular main body plate 61 and two opposing side plates that stand up from both sides of the main body plate 61 in the longitudinal direction. portions 62 and 63, an upper plate portion 64 standing up from one end in the transverse direction of the main body plate portion 61, an opposing opening 65 facing the main body plate 61, and a lower opening 66 facing the upper plate portion 64. We are prepared. Therefore, the storage main body part 6 of this embodiment has a rectangular parallelepiped shape, and is provided with a storage part for the drug administration tool 10 inside.

In this embodiment, the lid part 7 of the storage body 5 includes a base plate part 71 that can be attached to the opposing opening 65 of the storage body part 6 and a lower plate part 72 that can be attached to the lower part of the storage body part 6. Be prepared.
The drug administration tool 10 is configured such that the gasket pressing member 23 is located inside the lower part of the storage body 5 (specifically, so that the pressing operation part 23a of the gasket pressing member 23 faces the lower plate part 72). It is stored in the storage body 5.

As shown in FIGS. 9 to 11, the lid portion 7 includes a stopper portion 50 that protrudes from the lower side surface of the base plate portion 71. As shown in FIGS.
As shown in FIGS. 9 to 11, the stopper part 50 includes a base part 54 that projects from the lower side surface of the base plate part 71, two extending parts 52 and 53 that extend forward from the base part 54 and face each other, and two opposing parts. A cutout 55 is provided between the extensions 52 and 53 and the base 54 to allow the main body of the outer cylinder 21 to pass through.
The cylindrical case 4 includes two engaging parts 52 and 53, and when the stopper part 50 is attached to the cylindrical case 4, the base 54 is connected to one side opening of the cylindrical case 4. The distal end portions of the two extending portions 52 and 53 are engaged with the engaging portion of the cylindrical case 4. Further, the base end portion of the base portion 54 protrudes from the side opening of the cylindrical case.
In this embodiment, the stopper part 50 has a U-shape, passes through the cylindrical case 4, sandwiches the outer cylinder 21 of the prefilled syringe 2 on the inside of the U-shape, and has two side openings. By being inserted into the case so as to penetrate through the section, axial movement of the prefilled syringe is suppressed.

As shown in FIGS. 4 and 5, when the stopper part 50 is attached to the cylindrical case 4, one end of the base is inserted from the side opening 43b of one of the two side openings of the cylindrical case 4. The tip portions of the two protruding portions 52 and 53 protrude from the other side opening 43a. Further, as shown in FIGS. 4 and 5, the bottom surface of the base 54 and the two extensions 52 and 53 of the stopper part 50 abuts the top surface of the outer surface protrusion 26 of the prefilled syringe 2, and the bottom surface of the stopper part 50 The upper surface of the base 54 is in contact with the upper edge of one side opening 43b of the cylindrical case 4, and the upper surface of the two extensions 52, 53 is in contact with the other side opening 43a of the cylindrical case 4. It is in contact with the upper edge of. As a result, the stopper part 50 is easily held between the upper edges of the side openings 43a and 43b of the cylindrical case 4 and the outer surface protrusion 26 of the prefilled syringe 2 in the cylindrical case 4. It is designed not to be withdrawn.

Next, the functions of the drug administration device 1 according to the embodiment of the present invention will be explained.
In the drug administration device 1 of the present invention, as shown in FIGS. 1, 2, and 4, when the stopper portion 50 is inserted into the drug administration device 10 of the present invention (installed state), The tip portion including 31a protrudes from the tip of the cylindrical case 4, and the rear part of the gasket pressing member 23 attached to the gasket 22 protrudes from the rear end of the cylindrical case 4. The protrusion length of the distal end portion of the double-ended needle 3 including the distal needle portion 31a from the distal end of the cylindrical case 4 is preferably 2 to 20 mm, particularly preferably 12 to 17 mm.

Then, as shown in FIG. 15, the storage body 6 is removed from the drug administration device 1, and as shown in FIG. 16, the lid 7 is removed from the drug administration device 10. The stopper portion 50 is detached from the drug administration device 1. As a result, the locking state of the outer surface protrusion 26 of the prefilled syringe 2 by the stopper portion 50 is released. As a result, the outer surface protrusion 26 of the prefilled syringe 2 is pressed from the rear by the urging member 11, and the prefilled syringe 2 moves forward (in the direction of the double-ended needle 3).

The prefilled syringe 2 (specifically, the sealing member 24) and the double-ended needle 3 of this embodiment are housed in the cylindrical case 4 so that their central axes are substantially the same. Furthermore, even when the prefilled syringe 2 is moved by the pressure of the biasing member 11, the central axis of the prefilled syringe 2 (specifically, the sealing member 24) is aligned with the double-ended needle by the guide portions 14a, 14b, etc. 3 slides forward (in the direction of the double-ended needle 3) while maintaining almost the same state.

The biasing force of the prefilled syringe 2 by the biasing member 11 is such that at least after the stopper portion 50 is removed, the sealing member 27 of the sealing member 24 of the prefilled syringe 2 is pierced by the rear end needle portion 31b of the double-ended needle 3. Press the prefilled syringe so that the Further, the biasing force of the prefilled syringe 2 by the biasing member 11 is applied until the outer surface protrusion 26 of the prefilled syringe 2 comes into contact with the movement regulating abutment part 46a of the second storage part 46 of the cylindrical case 4. 2 can be moved forward (in the direction of the double-ended needle 3), and furthermore, after the outer surface protrusion 26 of the prefilled syringe 2 comes into contact with the movement-restricting contact part 46a of the second storage part 46 of the cylindrical case 4. In this case, it is preferable that the prefilled syringe 2 is further pressed.

The biasing force of the prefilled syringe 2 by the biasing member 11 varies depending on the piercing resistance of the seal member 27 by the rear end needle portion 31b of the double-ended needle 3, but is preferably 2.7N to 4.7N, preferably 3. It is preferably 0N to 4.3N, more preferably 3.4N to 4.0N. Further, the thickness of the sealing member 27 is preferably 0.7 to 1.5 mm, particularly preferably 0.8 to 1.2 mm. Further, the distance between the tip of the rear end needle portion 31b of the double-ended needle 3 and the upper surface of the sealing member 27 is preferably 2 to 6 mm, particularly preferably 3 to 5 mm. Further, the distance until the entire rear end needle portion 31b of the double-ended needle 3 penetrates the sealing member 27 (in other words, the distance moved by the biasing member toward the distal end of the prefilled syringe in the cylindrical case) is 4. ~10 mm is preferred, and 5 ~ 8 mm is particularly preferred.
The coil spring used in the biasing member 11 is preferably a spring that has a set spring constant of 0.1 N/mm or more and can be compressed by 40 mm or more. Further, it is preferable that the inner diameter of the spring is 10 mm to 20 mm, the height when the spring is compressed is 5 mm or less, and the height when the spring is released is 40 mm to less than 50 mm.

Next, the operation of the drug administration device 1 according to the embodiment of the present invention will be explained.
When the lid part 7 equipped with the stopper part 50 is removed from the drug administration device 1 from the state in which the stopper part is attached as shown in FIGS. When the state is released, the outer surface projection 26 of the prefilled syringe 2 is pressed from the rear by the urging member 11, and the prefilled syringe 2 moves forward (in the direction of the double-ended needle 3).

Then, as shown in FIGS. 16 and 17, the sealing member 27 of the sealing member 24 of the prefilled syringe 2 that has moved forward is pierced by the rear end needle portion 31b of the double-ended needle 3. Thereby, the inside of the needle tube 21 of the double-ended needle 3 communicates with the inside of the prefilled syringe 2. Further, the moved outer surface protrusion 26 enters into the second storage part 46 of the cylindrical case 4 and comes into contact with the contact part 46a of the second storage part 46, as shown in FIGS. 16 to 18. contact, and further forward movement is restricted. As shown in FIG. 17, when the sealing member 24 of the prefilled syringe 2 shown in FIGS. 12 and 13 is pierced by the rear end needle portion 31b of the double-ended needle 3, the gasket pressing member 23 is The rear portion including the pressing operation portion 23a protrudes from the cylindrical case 4 by a predetermined length.

Then, by removing the cap 34 of the double-ended needle 3, preparations for drug administration are completed. Further, the gasket pressing member 23 can be pressed until the pressing operation portion 23a comes into contact with the rear end surface of the cylindrical case 4, and the medicine can be discharged by the amount of movement of the gasket pressing member 23.
The movable distance of the gasket pressing member 23 (the distance between the rear end surface of the cylindrical case 4 and the distal end surface of the pressing operation part 23a of the gasket pressing member 23) varies depending on the capacity of the prefilled syringe used, the drug to be administered, etc. However, it is preferably 4 to 10 mm, more preferably 5 to 7 mm, and particularly preferably 5.5 to 6.5 mm.

Further, the drug administration device used in the drug administration device of the present invention may be as shown in FIG. 19.
The basic configuration of the drug administration device 10a used in this embodiment is the same as the drug administration device 10 described above, and the only difference is that it includes a cap connecting member 35.
In the drug administration device 10a of this embodiment, similarly to the drug administration device 10 described above, the double-ended needle 3 is attached to a needle tube 31 having a tip end needle portion 31a and a rear end needle portion 31b, and an intermediate portion of the needle tube 31. The needle cap 34 includes a hub 32 with a rear end attached to the hub 32, a closed tip, and a double-ended needle cap 34 that covers the tip needle portion 31a.

The drug administration device 10a includes a cap connecting member 35 having a connecting portion 35a with the double-ended needle cap 34 and a cylindrical case mounting portion 35b. The cylindrical case mounting portion 35b is a short cylindrical portion having an inner surface shape corresponding to the outer surface shape of the tip of the cylindrical case 4. The cap connecting portion 35a is a short, small-diameter cylindrical portion having an inner surface shape corresponding to the outer surface shape of the side portion of the double-ended needle cap 34. A cap connecting member 35 is provided. The cylindrical case mounting portion 35b is a short cylindrical portion having an inner surface shape corresponding to the outer surface shape of the tip of the cylindrical case 4.

Further, the cap connecting portion 35a includes a connecting portion 35c that connects the cylindrical case mounting portion 35b and the cap connecting portion 35a. The cylindrical case mounting portion 35b of the cap connecting portion 35a is removable from the cylindrical case 4, and the cap connecting portion 35a is substantially not removable from the double-ended needle cap 34. Further, it is preferable that the connecting portion 35c seals the tip opening 40 of the cylindrical case 4.
In the drug administration device 10a of this embodiment, when the cap connecting member 35 is removed from the cylindrical case 4, the double-ended needle cap 34 is also removed from the double-ended needle 3 at the same time, so that the work of removing the double-ended needle cap 34 is simplified. It's easy.

Next, a drug administration device 1a according to another embodiment of the present invention shown in FIG. 20 will be described.
FIG. 21 is an explanatory diagram for explaining the action of the drug administration device of the embodiment shown in FIG. 20. FIG. 22 is an explanatory diagram for explaining the action of the drug administration device of the embodiment shown in FIG. 20.
The basic structure of the drug administration device 1a of this embodiment is the same as the drug administration device 1 described above, and the difference is that the tip of the double-ended needle cap 34a is held on the inner surface of the upper plate portion 64 of the storage main body portion 6a. The point is that there is.

The drug administration device 1a of this embodiment includes a mounting portion for attaching the double-ended needle cap 34a to the storage main body portion 6a. Specifically, the mounting portion is formed by a recess 34b extending downward from the tip of the double-ended needle cap 34a, and a protrusion 64a of the storage body 6a that enters into the recess 34b of the double-ended needle cap 34a and engages with the recess 34b. It is formed. Note that the tip of the double-ended needle cap 34a only needs to be held on the inner surface of the upper plate portion 64 of the storage main body portion 6a, and may have any form, and may not be fixed. It's okay.

Next, the operation of the drug administration device 1a of this embodiment will be explained.
When the lid part 7 equipped with the stopper part 50 is removed from the drug administration device 1a from the state in which the stopper part is attached as shown in FIG. The locked state of the side protrusion 26 is released, the prefilled syringe 2 moves forward, and the sealing member 27 of the sealing member 24 is pierced by the rear end needle portion 31b of the double-ended needle 3.
Then, as shown in FIG. 22, when the drug administration device 10 is moved downward, the double-ended needle cap 34a remains in the storage main body 6, and the double-ended needle cap 34 is detached from the drug administration device 10. This completes preparation for administration.

Next, a drug administration device 1b according to another embodiment of the present invention shown in FIG. 23 will be described.
The basic structure of the drug administration device 1b of this embodiment is the same as the drug administration device 1 described above, and the difference is that the tip of the double-ended needle cap 34a is held on the inner surface of the main body plate portion 61 of the storage main body portion 6b. The point is that there is.

The drug administration device 1b of this embodiment includes a holding portion 61a for holding the double-ended needle cap 34 to the storage body portion 6b. Specifically, the holding part 61a is formed by a protrusion that protrudes from the inner surface of the main body plate part 61 of the storage main body part 6b, and at least a part of the outer part of the double-ended needle cap 34 is attached to the tip of the protrusion. It is equipped with a gripping part that holds the . For example, the cap holding portion 61a may be formed of two protrusions, and a portion of the outer side of the double-ended needle cap 34 may be held between the tips of the two protrusions. Note that the tip of the double-ended needle cap 34 only needs to be held on the inner surface of the main body plate section 61 of the storage main body section 6b, and may have any form, and may not be fixed. It's okay.

Next, the operation of the drug administration device 1b of this embodiment will be explained.
When the lid part 7 equipped with the stopper part 50 is removed from the drug administration device 1b from the state in which the stopper part is attached as shown in FIG. The locking state of the outer surface protrusion 26 is released, the prefilled syringe 2 moves forward, and the sealing member 27 of the sealing member 24 is pierced by the rear end needle part 31b of the double-ended needle 3. .
22, when the drug administration device 10 is moved downward, the double-ended needle cap 34 remains in the storage main body 6, and the double-ended needle cap 34 is separated from the drug administration device 10. This completes preparation for administration.

Next, a drug administration device 1c according to another embodiment of the present invention shown in FIG. 24 will be described.
FIG. 25 is an inner view (right side view) of the storage main body used in the drug administration device of the embodiment shown in FIG. 24. FIG. 26 is a sectional view taken along the line CC in FIG. 25.
The basic configuration of the drug administration device 1c of this embodiment is the same as the drug administration device 1 described above, and the only difference is the form of the storage body 5a.

In the drug administration device 1c of this embodiment, as shown in FIGS. 24 to 26, the storage body 5a includes a storage main body portion 6c and a lid portion 7a.
The storage main body part 6c includes a rectangular main body plate part 61, two opposing side plate parts 62 and 63 that stand up from both sides of the main body plate part 61 in the longitudinal direction, and stand up from both ends of the main body plate part 61 in the short direction. It includes an upper plate part 64, a lower plate part 68, and an opposing opening 65 facing the main body plate part 61. Further, the storage main body section 6c includes a stopper section 50a at a lower portion of the main body plate section 61 (a predetermined distance above the lower plate section 68). Furthermore, the storage main body 6c of this embodiment includes an internal protrusion 61b that can come into contact with the distal end portion of the outer cylinder main body of the prefilled syringe 2. This internal protrusion 61b suppresses the inclination of the stored prefilled syringe into which the stopper portion 50a has entered. In this storage main body section 6c, only the portion facing the main body plate section 61 has a side opening 65.

As described above, the stopper portion 50a includes a base portion 54 protruding from the lower side surface of the main body plate portion 61, two extending portions 52 and 53 extending forward from the base portion 54 and facing each other, and two extending portions 52 and 53 facing each other. A notch 55 is provided between the parts 52 and 53 and the base 54 to allow the main body of the outer cylinder 21 to pass through. In this embodiment, the stopper part 50a has a U-shaped form, and has a penetrating side opening that penetrates the cylindrical case 4 and sandwiches the outer cylinder 21 of the prefilled syringe 2 inside the U-shape. By inserting it into the syringe, the axial movement of the prefilled syringe is suppressed.

As shown in FIGS. 24, 27, and 28, the lid 7a is a plate-like member and includes a base plate 71 that can be attached to the opposing opening 65 of the storage main body 6c. As shown in FIGS. 27 and 28, the lid portion 7a also includes a cap holding portion 73 that protrudes inward from the upper inner surface, specifically, a cap holding portion 73 that protrudes from the base plate portion 71, and an outer cylinder guide portion 74. , 75. A portion of the side portion of the double-ended needle cap 34 is held by the cap holding portion 73 . Specifically, the cap holding part 73 is a protruding part and includes a gripping part at its distal end that grips a part of the outer side of the double-ended needle cap 34. In this embodiment, the cap holding part 73 is formed of two protrusions, and a part of the outer side of the double-ended needle cap 34 is held between the tips of the two protrusions. Note that the tip of the double-ended needle cap 34 only needs to be held by the lid 7a, and may have any form, or may be fixed.

Next, the operation of the drug administration device 1c of this embodiment will be explained.
When the storage body section 6c equipped with the stopper section 50a is removed from the drug administration device 1c with the stopper section attached as shown in FIG. The locked state of the outer surface protrusion 26 is released, the prefilled syringe 2 moves forward, and the sealing member 27 of the sealing member 24 is pierced by the rear end needle portion 31b of the double-ended needle 3.
In the state shown in FIGS. 27 and 28, the drug administration tool 10 is held by the lid 7a. Then, as shown in FIG. 29, when the drug administration device 10 is moved downward, the double-ended needle cap 34a remains on the lid portion 7a, and the double-ended needle cap 34 is separated from the drug administration device 10. This completes preparation for administration.

In addition, when providing a stopper part in a storage main body part, as shown in FIG. 30, a stopper part 50b may be a separate member. In the storage main body part 6e of this embodiment, the stopper part 50b includes a base part 84, two extending parts 81 extending forward from the base part 84 and facing each other, and an outer cylinder 21 formed between the two extending parts 81. A stopper member 80 is provided with a notch for passing through the main body.
In this embodiment, the storage main body portion 6e includes a slit 91 for storing the base portion 84 of the stopper member 80, and an engagement recess 92. The stopper member 80 includes an engagement protrusion 85 on the side of the base 84 that engages with the engagement recess 92 . Further, the storage main body 6e includes two opposing protrusions 93 each having an inclined surface for guiding the base 84 of the stopper member 80 into the slit 91.
When such a separate stopper member 80 is used, the stopper member 80 may be attached to the drug administration device 10 and then its base 84 may be attached to the storage main body portion 6d.

Furthermore, the drug administration device used in the drug administration device of the present invention may be of the type shown in FIG. 31 and subsequent figures. When used in the drug administration device 1a shown in FIG. 20, the double-ended needle cap 34a shown in FIGS. 20 to 22 is used as the double-ended needle cap.

First, a drug administration device 10b according to another embodiment of the present invention shown in FIG. 31 will be described.
FIG. 32 is a front view of the gasket pressing member movement distance regulating member used in the drug administration tool shown in FIG. 30. FIG. 33 is a right side view of the gasket pressing member movement distance regulating member shown in FIG. 32. FIG. 34 is a plan view of the gasket pressing member movement distance regulating member shown in FIG. 32. FIG. 35 is a sectional view taken along line DD in FIG. 33.

The basic configuration of the drug administration device 10b of this embodiment is the same as the drug administration device 10 described above, and the difference is in the protruding length of the gasket pressing member 23 from the rear end of the cylindrical case 4 and the length of the gasket pressing member 23. The only difference is that the gasket pressing member movement distance regulating member 9 is detachably attached to the gasket pressing member.
The drug administration device 10b of this embodiment is detachably attached to the side of the gasket pressing member 23, and the distal end is spaced apart from the rear end of the cylindrical case 4, and when the gasket pressing member 23 moves forward, A gasket pressing member movement distance regulating member 9 is provided, the tip of which can come into contact with the rear end of the cylindrical case 4.

As shown in FIGS. 32 to 35, the gasket pressing member movement distance regulating member 9 of this embodiment has a gasket pressing member mounting portion 91, a gripping portion 92, a tip side contact portion 93, and a rear end side contact portion 94. We are prepared. As shown in FIGS. 34 and 35, the gasket pressing member mounting portion 91 is an axially penetrating plate that is removably mounted on one flat plate portion of the axially extending main body portion of the gasket pressing member 23 that has a cross-shaped cross section. A recessed portion 91a is provided.
The gripping part 92 is a flat plate-like part that extends in the lateral direction from the side of the gasket pressing member mounting part 91, and is used to grip and hold the gasket pressing member movement distance regulating member 9 when removing it from the gasket pressing member 23. It can be used as a part.

The distal end contact portion 93 restricts further movement of the gasket pressing member 23 toward the distal end after contact with the rear end surface of the cylindrical case 4 . The distal end contact portion 93 is capable of contacting the rear end surface of the cylindrical case 4 after the gasket pressing member moves. In this embodiment, the distal end contact portion 93 has a flat plate shape connected to the distal end of the gasket pressing member mounting portion 91. As shown in FIG. 34, the tip side contact portion 94 is preferably semicircular.

The rear end contact portion 94 is in contact with the distal end surface of the pressing operation portion 23a of the gasket pressing member 23, and is for regulating rearward movement of the gasket pressing member movement distance regulating member 9. In this embodiment, the rear end side abutting portion 94 is in the form of a flat plate connected to the rear end of the gasket pressing member mounting portion 91 . As shown in FIG. 35, the rear end side contact portion 94 is preferably semicircular.

In the drug administration tool 10b of this embodiment, by pressing the pressing operation part 23a of the gasket pressing member 23, the distal end contact part 93 of the gasket pressing member movement distance regulating member 9 is brought into contact with the rear end surface of the cylindrical case 4. It can be moved until it abuts, and a predetermined amount of medicine can be ejected (administered). Furthermore, when it is necessary to eject (administer) the drug, the gasket pressing member movement distance regulating member 9 is removed from the gasket pressing member and the pressing operation portion 23a of the gasket pressing member 23 is pressed. The pressing operation part 23a can be moved until it comes into contact with the rear end surface of the cylindrical case 4, and a predetermined amount of medicine can be additionally ejected (additional administration).

Next, a drug administration device 10c according to another embodiment of the present invention shown in FIG. 36 will be described. FIG. 37 is a right side view of the gasket pressing member movement distance regulating member used in the drug administration device shown in FIG. 36. FIG. 38 is a bottom view of the gasket pressing member movement distance regulating member used in the drug administration device shown in FIG. 36.

The basic configuration of the drug administration device 10c of this embodiment is the same as the drug administration device 10 described above, and the differences are the protrusion length of the gasket pressing member 23 from the rear end of the cylindrical case 4 and the length of the gasket pressing member 23. The only difference is that the first gasket pressing member movement distance regulating member 9a and the second gasket pressing member movement distance regulating member 9b are detachably attached to the gasket pressing member.
The basic structure of this drug administration device 10c is the same as the drug administration device 10 described above, and the difference is the length of the gasket pressing member 23 protruding from the rear end of the cylindrical case 4, and the ability to be attached to and detached from the gasket pressing member 23. The only difference is that a first gasket pressing member movement distance regulating member 9a and a second gasket pressing member movement distance regulating member 9b are provided.

The drug administration tool 10c of this embodiment is detachably attached to the side of the gasket pressing member 23, and the distal end is separated from the rear end of the cylindrical case 4, and when the gasket pressing member 23 moves forward, A first gasket pressing member movement distance regulating member 9a and a second gasket pressing member movement distance regulating member 9b are provided, the distal end of which can come into contact with the rear end of the cylindrical case 4.

The first gasket pressing member movement distance regulating member 9a and the second gasket pressing member movement distance regulating member 9b of this embodiment are the same as the gasket pressing member movement distance regulating member 9 shown in FIGS. 32 to 35. It includes a mounting part 91, a gripping part 92, a distal end contacting part 93, and a rear end contacting part 94.

The second gasket pressing member movement distance regulating member 9b is provided with a protrusion 95 provided on the rear end surface of the rear end side abutting portion 94, as shown in FIGS. 36 to 38, and as shown in FIG. In the state in which the first gasket pressing member movement distance regulating member 9a and the second gasket pressing member movement distance regulating member 9b are attached to the gasket pressing member 23, the second gasket pressing member movement distance regulating member 9b on the rear end side is It is intended to restrict withdrawal.

When the first gasket pressing member movement distance regulating member 9a is pulled out in the side direction to remove it from the state shown in FIG. However, the second gasket pressing member comes into contact with the protrusion 95 of the movement distance regulating member 9b, has a high detachment resistance, and regulates detachment. Therefore, in the drug administration tool 10c of this embodiment, the gasket pressing member movement distance regulating member is removed in the order of the second gasket pressing member movement distance regulating member 9b and the first gasket pressing member movement distance regulating member 9a.

In the drug administration tool 10c of this embodiment, by pressing the pressing operation part 23a of the gasket pressing member 23, the distal end side abutting part 93 of the second gasket pressing member movement distance regulating member 9b located on the distal side It can be moved until it comes into contact with the rear end surface of the shaped case 4, and a predetermined amount of medicine can be ejected (administered). Further, when ejection (administration) of the drug is required, the second gasket pressing member movement distance regulating member 9b is removed from the gasket pressing member and the pressing operation portion 23a of the gasket pressing member 23 is pressed. The gasket pressing member can be moved until the distal end contact portion 93 of the moving distance regulating member 9a comes into contact with the rear end surface of the cylindrical case 4, and a predetermined amount of medicine can be ejected (administered). Further, when ejection (administration) of the drug is required, the first gasket pressing member movement distance regulating member 9a is removed from the gasket pressing member and the pressing operation portion 23a of the gasket pressing member 23 is pressed, thereby pressing the gasket. The pressing operation portion 23a of the member can be moved until it comes into contact with the rear end surface of the cylindrical case 4, and a predetermined amount of medicine can be additionally ejected (additional administration).

Next, a drug administration device 10d according to another embodiment of the present invention shown in FIG. 39 will be described.
The basic configuration of the drug administration device 10d of this embodiment is the same as the drug administration device 10 described above, and the only difference is the form of the biasing member storage section.
In the drug administration device 10d of this embodiment, the rear end of the cylindrical case 4 is provided with a cylindrical urging member storage part that communicates with the first storage part 45 and has a smaller diameter than the first storage part 45. ing. The biasing member 11 is configured as a biasing member storage portion, and its rear end portion is not fixed to the cylindrical case 4.

Further, the drug administration device used in the drug administration device of the present invention may be as shown in FIG. 40.
A drug administration device 10e according to another embodiment of the present invention shown in FIG. 40 will be described. FIG. 41 is an explanatory diagram for explaining the action of the drug administration tool shown in FIG. 40.

The basic structure of the drug administration device 10e of this embodiment is the same as the drug administration device 10 described above, and the difference is that the drug administration device 10e of this embodiment has a tube for enclosing the tip needle portion 31a of the double-ended needle 3 protruding from the cylindrical case 4. The only difference is that a shaped member 101 is provided.
The drug administration device 10e of this embodiment is attached to the distal end of the cylindrical case 4, is slidable in the distal direction, and is designed to cover the distal end needle portion 31a of the double-ended needle 3 protruding from the cylindrical case 4. A cylindrical member 101 is provided.

The cylindrical member 101 is a short cylindrical body having an inner surface shape corresponding to the outer surface shape of the tip of the cylindrical case 4 . The cylindrical member 101 has a rib 102 on the inner surface of the rear end. The rib 102 is an annular rib. Note that the ribs 102 may be a plurality of ribs arranged circumferentially.
In the drug administration device 10e of the embodiment, the outer surface of the distal end of the cylindrical case 4 includes a first movement regulating rib 103 provided on the rear end side by a predetermined distance from the distal end of the cylindrical case 4; A second movement regulating rib 105 is provided on the distal end side of the movement regulating rib 103 by a predetermined length. The first movement regulating rib 103 and the second movement regulating rib 105 are annular ribs. Note that the ribs may be a plurality of ribs arranged circumferentially. Further, the second movement regulating rib 105 is provided with an annular recess 106 into which the rib 102 of the cylindrical member 101 can engage (enter into).

In the drug administration device 10e of this embodiment, by sliding the cylindrical member 101 in the distal direction after using the drug administration device 10e, the tip needle portion 31a of the double-ended needle 3 protruding from the cylindrical case 4 is covered. can do. Furthermore, the rib 102 of the slid cylindrical member 101 enters and engages the annular recess 106 of the second movement regulating rib 105 of the cylindrical case 4, thereby moving the rib 102 of the cylindrical member 101 toward the rear end side. The movement of the cylindrical member 101 can be restricted, and the state in which the distal needle portion 31a is covered by the cylindrical member 101 can be maintained.

Next, a drug administration device 10f according to another embodiment of the present invention shown in FIG. 42 will be described.
The basic structure of the drug administration device 10f of this embodiment is the same as the drug administration device 10 described above, and the difference is that the drug administration device 10f of this embodiment has a tube for enclosing the tip needle portion 31a of the double-ended needle 3 protruding from the cylindrical case 4. The only difference is that it includes a biasing member 114 that biases the shaped member 110 and the cylindrical member 110 in the distal direction.
The drug administration device 10f of this embodiment includes a cylindrical member 110 that is attached to the distal end of a cylindrical case 4 and for enclosing the distal end needle portion 31a of the double-ended needle 3 that protrudes from the cylindrical case 4; The cylindrical member 110 is provided with a biasing means 114 for biasing the member 110 toward the distal end, and the cylindrical member 110 can be slid rearward by being pressed toward the distal end.

The drug administration device 10f of this embodiment is attached to the distal end of the cylindrical case 4, is slidable in the distal direction, and is designed to cover the distal needle portion 31a of the double-ended needle 3 protruding from the cylindrical case 4. A cylindrical member 110 is provided.
The cylindrical member 110 is a short cylindrical body having an inner surface shape corresponding to the outer surface shape of the tip of the cylindrical case 4 . The cylindrical member 110 has a rib 102 on the inner surface of the rear end. The rib 102 is an annular rib. Note that the ribs 102 may be a plurality of ribs arranged circumferentially.

In the drug administration device 10f of the embodiment, on the outer surface of the distal end of the cylindrical case 4, a first movement regulating rib 103 provided on the rear end side by a predetermined distance from the distal end of the cylindrical case 4; A second movement regulating rib 116 is provided on the distal end side of the movement regulating rib 103 by a predetermined length. The first movement regulating rib 103 and the second movement regulating rib 116 are annular ribs. Note that the ribs may be a plurality of ribs arranged circumferentially.

The drug administration device 10f of this embodiment includes a biasing member 114 disposed on the outer periphery of the distal end of the cylindrical case 4. The biasing member 114 is disposed between the rear end of the cylindrical member 110 and the first movement regulating rib 103 of the cylindrical case 4, and biases the cylindrical member 110 in the distal direction and The distal end needle portion 31a of the double-ended needle 3 protruding from the cylindrical member 110 remains covered by the cylindrical member 110. In this embodiment, a coil spring is used as the biasing member 116, and the tip of the cylindrical case 4 passes through the biasing member 116.

Further, the inner rib 102 of the cylindrical member 110 contacts the second movement regulating rib 11 of the cylindrical case 4 and restricts further movement toward the tip and separation from the cylindrical case 4. .
In the drug administration device 10f of this embodiment, when the cylindrical member 110 is pushed backward (for example, when the tip needle part 31a punctures), it moves to the rear of the cylindrical case 4, and the tip of the double-ended needle 3 The needle portion 31a is exposed, and when the rearward pressure of the cylindrical member 110 is released, the tip needle portion 31a of the double-ended needle 3 protruding from the cylindrical case 4 is exposed again to the cylindrical member. 110 to return to the encapsulated state.

Further, in all the embodiments described above, the pressing operation portion 23a of the gasket pressing member 23 may be able to enter into the cylindrical case 4. By doing this, when the gasket pressing member 23 is pushed all the way, the pressing operation part 23a of the gasket pressing member is housed in the cylindrical case 4, thereby preventing the gasket pressing member 23 from being pulled out and completing the administration. It becomes a landmark.

Next, a drug administration device 1d according to another embodiment of the present invention shown in FIGS. 43 and 44 will be described.
FIG. 43 is a front view of a drug administration device 1d according to another embodiment of the present invention. FIG. 44 is a right side view of the drug administration device 1d shown in FIG. 43.
The drug administration device is preferably one that is sealed after the drug administration device 10 and a predetermined amount of hydrogen peroxide are put into the storage body 5b, like the drug administration device 1d. By adding hydrogen peroxide, bacteria on the surface of the internal drug administration device can be killed.

As shown in FIGS. 43 and 44, the storage body 5b includes a storage main body portion 6d and a lid portion 7b. Similar to the storage main body 6c described above, the storage main body 6d includes a rectangular main body plate 61, two opposing side plates 62 and 63 standing up from both sides of the main body plate 61 in the longitudinal direction, and a main body plate. 61 , a lower plate portion 68 facing the upper plate portion 64 , and an opposing opening 65 facing the main body plate portion 61 . Furthermore, the storage main body part 6d also includes a stopper part 50a at the lower part of the main body plate part 61 (a predetermined distance above the lower plate part 68). Furthermore, the storage main body 6d of this embodiment includes an internal protrusion 61b that can come into contact with the distal end portion of the outer cylinder main body of the prefilled syringe 2. This internal protrusion 61b suppresses the inclination of the stored prefilled syringe into which the stopper portion 50a has entered.

Also, in this storage main body part 6d, only the portion facing the main body plate part 61 is a side opening. The stopper portion 50a is the same as that described above. Further, in the storage body 5b of this embodiment, as shown in FIGS. 43 and 44, the storage main body portion 6d has a space behind the gasket pressing member 23 for taking out the drug administration tool 10 into which a finger or the like can enter. 79. Further, the storage main body 6d includes an outer surface protrusion 69 for joining the lid around the entire circumference of the side opening.

A functional sheet for adjusting the permeation amount of hydrogen peroxide is preferably used for the lid portion 7b. The functional sheet for adjusting the hydrogen peroxide permeation amount refers to a sheet that allows and regulates the permeation of hydrogen peroxide by diffusion. Specifically, it refers to a material that allows hydrogen peroxide gas to permeate through diffusion, but suppresses the permeation in a short period of time. If hydrogen peroxide is allowed to permeate for a short period of time, it will not be possible to create an atmosphere with a sufficiently high concentration of hydrogen peroxide during the external sterilization process of medical products after packaging. If it does not transmit at all, hydrogen peroxide will remain in the sheet. Therefore, the functional sheet for adjusting hydrogen peroxide permeation amount does not include materials such as paper and porous films that have pores through which hydrogen peroxide can easily pass.

The hydrogen peroxide passing function of the lid portion 7b can be evaluated by measuring the transpiration of an aqueous solution containing hydrogen peroxide (hydrogen peroxide solution). When a hydrogen peroxide solution is enclosed in a sheet film and left in an environment above room temperature, water and hydrogen peroxide gradually evaporate within the packaging film and fill the packaging film. In parallel with the vaporization and filling of hydrogen peroxide, hydrogen peroxide permeates into the sheet film body and then permeates therethrough, and the extent of this can be determined by the amount of reduction in hydrogen peroxide water droplets in the package. In other words, with a porous film that allows hydrogen peroxide to easily pass through, the hydrogen peroxide droplets will decrease and disappear in a short time, but with a sheet film that allows and restricts the permeation of hydrogen peroxide through diffusion, the hydrogen peroxide droplets will disappear. It takes a certain amount of time for the amount to decrease and disappear.

The lid part 7b had a hydrogen peroxide permeation amount adjustment function, and was adjusted so that the amount of hydrogen peroxide per the inner volume of the sheet was 300 mg/L in a container having an inner capacity of 0.2 mL per 1 cm ² of surface area of the sheet. After adding the hydrogen peroxide solution and sealing the container, the period during which the hydrogen peroxide droplets disappear under conditions of 55° C. and 25% RH is preferably in the range of 3 to 72 hours. In particular, it is preferable to have a hydrogen peroxide droplet disappearance period (transpiration) of 6 to 24 hours. Further, the lid portion 7b may be any material as long as it has the function of adjusting the amount of hydrogen peroxide permeation as a whole.

In the drug administration device 1d of this embodiment, the lid part 7b has a peelable fixing part 77 on the surface of the outer surface protrusion 69 provided around the entire periphery of the side opening of the storage main body part 6d. Fixed. The fixed portion 77 is formed by heat sealing, for example. Further, the drug administration device 1d of the embodiment includes a non-adhering portion 78 for starting peeling of the lid portion outside one end of the adhering portion 77.

1 Drug administration device 2 Prefilled syringe 3 Double-ended needle 4 Cylindrical case 5 Storage body 6 Storage main body portion 7 Lid portion 10 Drug administration device 11 Biasing member 50 Stopper portion

Claims (17)

A drug administration device comprising a hollow double-ended needle having a tip needle portion and a rear needle portion, a prefilled syringe, and a cylindrical case housing the prefilled syringe so that its tip side faces the rear needle portion of the double-ended needle. A drug administration device comprising a device and a storage body for storing the drug administration device,
The cylindrical case has a side opening at the rear end, stores the double-ended needle in such a way that it is immovable and the tip portion including the distal needle portion protrudes, and the prefilled syringe is housed in the cylindrical case. is stored so as to be movable in the direction of the double-ended needle,
The prefilled syringe includes an outer cylinder having an outer surface protrusion at its rear end, a sealing member that seals the tip of the outer cylinder and allows the rear end needle part of the double-ended needle to pass through, and the outer cylinder. A gasket member capable of sliding in a cylinder in a liquid-tight state, and a gasket pressing member whose rear part protrudes from the cylindrical case,
The storage body is capable of storing the drug administration device and includes a storage main body portion having an opening, and a lid portion that can be attached to the opening of the storage main body portion,
The drug administration tool includes a biasing member that contacts the outer cylinder and biases the prefilled syringe in the direction of the double-ended needle,
The storage body is provided on the inner surface of the storage main body or the lid, removably enters the side opening of the cylindrical case, comes into contact with the front surface of the outer surface protrusion, and holds the prefilled syringe. comprising a stopper portion that restricts movement of the double-ended needle in the direction of the double-ended needle;
The storage main body includes a rectangular main body plate, two opposing side plates that stand up from both longitudinal sides of the main body plate, and an upper plate that stands up from one short side of the main body plate. and an opposing opening that faces the main body plate, and a lower opening that faces the upper plate, and the lid includes a base plate that can be attached to the opposing opening of the storage main body; a lower plate portion that can be attached to the lower opening of the storage body, and the drug administration device is housed in the storage body such that the gasket pressing member is located inside the lower part of the storage body. , furthermore, the stopper part is provided in the storage body, and further,
The biasing member is configured to cause the sealing member of the prefilled syringe to be pierced by the rear end needle portion of the double-ended needle after the drug administration tool is detached from the storage main body portion or the lid portion having the stopper portion. A drug administration device, characterized in that the prefilled syringe is pressed so that it is in the open state. The double-ended needle includes a needle tube having the tip needle portion and the rear needle portion, a hub attached to the intermediate portion of the needle tube, a rear end attached to the hub, a tip closed, and the tip needle 2. The drug administration device of claim 1 , further comprising a double-ended needle cap enclosing the needle. The drug administration device according to claim 2 , wherein the storage body includes a cap holding portion for holding the double-ended needle cap on the upper inner surface of the main body plate portion of the storage body portion or on the inner surface of the upper plate portion. . A drug administration device comprising a hollow double-ended needle having a tip needle portion and a rear needle portion, a prefilled syringe, and a cylindrical case housing the prefilled syringe so that its tip side faces the rear needle portion of the double-ended needle. A drug administration device comprising a device and a storage body for storing the drug administration device,
The cylindrical case has a side opening at the rear end, stores the double-ended needle in such a way that it is immovable and the tip portion including the distal needle portion protrudes, and the prefilled syringe is housed in the cylindrical case. is stored so as to be movable in the direction of the double-ended needle,
The prefilled syringe includes an outer cylinder having an outer surface protrusion at its rear end, a sealing member that seals the tip of the outer cylinder and allows the rear end needle part of the double-ended needle to pass through, and the outer cylinder. A gasket member capable of sliding in a cylinder in a liquid-tight state, and a gasket pressing member whose rear part protrudes from the cylindrical case,
The storage body is capable of storing the drug administration device and includes a storage main body portion having an opening, and a lid portion that can be attached to the opening of the storage main body portion,
The drug administration tool includes a biasing member that contacts the outer cylinder and biases the prefilled syringe in the direction of the double-ended needle,
The storage body is provided on the inner surface of the storage main body or the lid, removably enters the side opening of the cylindrical case, comes into contact with the front surface of the outer surface protrusion, and holds the prefilled syringe. comprising a stopper portion that restricts movement of the double-ended needle in the direction of the double-ended needle;
The storage main body includes a rectangular main body plate, two opposing side plate parts that stand up from both longitudinal sides of the main body plate, an upper plate that stands up from both lateral sides of the main body plate, and The drug administration device includes a lower plate portion and an opposing opening facing the main body plate portion, the lid portion includes a base plate portion that can be attached to the opposing opening of the storage main body portion, and the drug administration device The pressing member is housed in the housing so as to be located inside a lower part of the housing, and the stopper portion is provided on the housing, and further,
The biasing member is configured to cause the sealing member of the prefilled syringe to be pierced by the rear end needle portion of the double-ended needle after the drug administration tool is detached from the storage main body portion or the lid portion having the stopper portion. A drug administration device, characterized in that the prefilled syringe is pressed so that it is in the open state. The double-ended needle includes a needle tube having the tip needle portion and the rear needle portion, a hub attached to the intermediate portion of the needle tube, a rear end attached to the hub, a tip closed, and the tip needle 5. The drug administration device of claim 4, further comprising a double-ended needle cap enclosing the needle. 6. The drug administration device according to claim 5 , wherein the storage body includes a cap holding part that protrudes inward from the upper inner surface of the lid part and holds the double-ended needle cap. The double-ended needle includes a needle tube having the tip needle portion and the rear needle portion, a hub attached to the intermediate portion of the needle tube, a rear end attached to the hub, a tip closed, and the tip needle 7. The drug administration device includes a cap connecting member that includes a removable cylindrical case mounting portion and a connecting portion with the double-ended needle cap. The drug administration device according to any one of the above. The stopper portion includes a base, two extending portions extending forward from the base and facing each other, and a notch formed between the two extending portions and the base for penetrating the main body of the outer cylinder. The cylindrical case includes an engaging part with the two extension parts, and when the stopper part is attached to the cylindrical case , the base part is attached to the side of the cylindrical case. 8. The drug administration device according to claim 1, wherein the distal end portions of the two extending portions are engaged with the engaging portion of the cylindrical case. The double-ended needle includes a needle tube having the tip needle portion and the rear needle portion, a hub attached to an intermediate portion of the needle tube, one end attached to the hub, a rear end closed, and a hub attached to the intermediate portion of the needle tube. 9. An elastic sleeve enveloping the needle, the elastic sleeve being pressed in the direction of the hub to allow the rear end needle to penetrate. Drug administration device as described. The cylindrical case includes two side openings facing each other, and the stopper portion includes a base, two extending portions extending forward from the base and facing each other, and the two extending portions and the stopper portion. a notch formed between the base parts for passing through the main body of the outer cylinder, and when the stopper part is attached to the drug administration device, the base part is connected to one side of the cylindrical case. The drug administration device according to any one of claims 1 to 9 , wherein the distal end portions of the two extension portions are engaged with the other side opening. The cylindrical case is configured to allow the prefilled syringe to be inserted into the prefilled syringe after the stopper portion is detached from the drug administration tool and the sealing member of the prefilled syringe is pierced by the rear end needle portion of the double-ended needle. The drug administration device according to any one of claims 1 to 10, further comprising an abutment portion that abuts the distal end surface of the outer surface protrusion to restrict movement. The cylindrical case includes a guide portion that protrudes inward from an inner surface of the cylindrical case at a position corresponding to the cylindrical body of the stored prefilled syringe and guides sliding of the prefilled syringe. Item 12. The drug administration device according to any one of Items 1 to 11. The biasing member has a tip contacting the rear surface of the outer surface protrusion of the prefilled syringe, a rear end contacting an end of the biasing member storage portion of the cylindrical case, and a gasket pressing member of the prefilled syringe. 13. The drug administration device according to any one of claims 1 to 12, wherein the drug administration device is a compressed coil spring having a through-hole. The gasket pressing member includes a pressing operation part at the base end, and after the stopper part is removed, the sealing member of the prefilled syringe is pierced by the rear end needle part of the double-ended needle. The drug administration device according to any one of claims 1 to 13, wherein a base end portion including the pressing operation portion protrudes from the cylindrical case in the state. The drug administration device is removably attached to the side of the gasket pressing member, and has a distal end spaced apart from a rear end of the cylindrical case, and a forward movement of the gasket pressing member causes the distal end to be removed. The drug administration device according to any one of claims 1 to 14, further comprising a gasket pressing member movement distance regulating member that can come into contact with the rear end of the cylindrical case. The drug administration device includes a cylindrical member that is attached to the distal end of the cylindrical case, is slidable in the distal direction, and is configured to cover the distal end needle of the double-ended needle that protrudes from the cylindrical case. The drug administration device according to any one of claims 1 to 15, comprising: The drug administration device includes a cylindrical member attached to the distal end of the cylindrical case and for enclosing the distal end needle portion of the double-ended needle that protrudes from the cylindrical case, and a cylindrical member that is attached to the distal end of the cylindrical case and that extends in the distal direction. 16. The drug administration device according to claim 1, further comprising a biasing means for biasing the cylindrical member, wherein the cylindrical member is slidable rearward when pressed.

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