JPS6046083B2 - cosmetics - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a cosmetic composition, in particular a skin astringent cosmetic composition, which is characterized by blending an extract of staghorn grass with vitamin C. hydrochloride and/or L-ascorbic acid.

Conventionally, the following methods have been used to impart a skin astringent effect to cosmetics. 5 A physical product that uses the phenomenon of lowering the skin surface temperature due to the heat of evaporation of ethanol, isopropyl alcohol, etc.

5. Cationic (e.g. aluminum chloride, basic aluminum, chlorohydroxyaluminum, etc.) or anionic (aluminum chloride, etc.) that binds to protein functional groups on the skin surface.
Contains an astringent (for example, organic acids such as citric acid and tartaric acid) to tighten the skin.

Contains Hamamelis extract, Hypericum perforatum extract, horse chestnut extract, etc. containing 6 tannin compounds.

Stimulating peripheral nerves with gunfer, menthol, etc.
Something that makes the effect feel sensual. Among these astringents, 5 is not very effective when used in small amounts, but when used in large amounts, it causes temporary but strong irritation, and the astringent effect is short-lasting.

The amount of the cationic astringent (5) must be kept as low as possible from the viewpoint of skin safety, and sufficient effects cannot be expected.

Furthermore, since anionic astringents are considerably more acidic than the pH range of the skin, it is common practice to combine them with pH adjusters and buffers, but the astringent effect is not fully satisfactory. do not have. Furthermore, when using tannin-based compounds contained in Hamamelis extract, etc., as an active ingredient, they are often unstable to light and temperature, and may cause significant discoloration due to contamination with iron ions, etc. may occur,
It cannot be blended in a large enough amount to achieve sufficient effects. It can be said that it is a matter of feeling. On the other hand, Odoricum extract is used in Fragrance Journal Rooster, 1
01-105 (1978), it is known that it has effects such as astringency and blood contraction, and is used in general cosmetics such as hair tonics and lotions.

Also, in Europe, it has been used as a decoction for gynecological diseases and as a sputum medicine since the Middle Ages. However, when the extract of Odoricum is added alone to cosmetics, its astringent effect is small, and even when trying to obtain a certain degree of astringent effect, a large amount (usually about 5% by weight or more) must be added. Moreover, even if the amount added is increased beyond this amount, the effect will not increase, and it will not be possible to impart a significant astringent effect to cosmetics.

In view of the current situation, the present inventors have developed a method that is safe for the skin and that is effective for the skin by combining and formulating a specific drug with an extract of Odoricum in order to exhibit its effect significantly with as little amount as possible. In addition, we thought that it would be possible to exert sufficient effects as a skin astringent, and as a result of systematically and repeatedly conducting a huge number of experiments on the combination of Nederopsis extract and various drugs, we found that Nederroum extract and vitamin B6 hydrochloric acid. We have obtained new knowledge that the astringent effect can be significantly improved when combined with salt and/or L-ascorbic acid, and based on this knowledge, we have completed the present invention.

That is, the present invention provides a cosmetic composition with an excellent skin astringent effect, which is characterized in that it contains an extract of sterilium extract and vitamin B6 hydrochloride and/or L-ascorbic acid.

The extract used in the present invention is prepared by grinding the stems, leaves, and flowers of the sterilium in a mixed extract of water and a polar solvent such as 1,3 butylene glycol, propylene glycol, or ethanol, and then adding the extract to the solution. It is extracted at room temperature and then concentrated, and contains active ingredients such as polyphenols, sugars, and amino acids.

As a commercially available product, for example, French SOMCI-CHIM
EXTRAITD″0RTIEBLANC1 from IE
It is available under the name 1E. This extract should be added in a range of 0.01% to 1% by weight (preferably 0% by weight) based on cosmetics.
．． 2 to 1% by weight), and further contains vitamin octahydrochloride and/or L-ascorbic acid. If the amount of Odoricum extract is less than 0.01% by weight, it will not be effective.
If the amount exceeds 1%, the coloring of the cosmetic will become noticeable, which is not preferable. Vitamin B6 used in the present invention
Hydrochloride is a derivative of vitamin B6, and vitamin 8 is a derivative of vitamin B6,
Animal's. It exists in the skin and serum, and its deficiency is said to cause seborrheic dermatitis, hypopigmentary anemia, peripheral neuritis, etc.

The amount of vitamin B6 hydrochloride is 0.0 of the extract
0.001 to 1 for cosmetics containing 1 to 1%
Weight% (preferably 0.01 to 0.3%)! It is.
If it is less than 0.001% by weight, the effect of improving the astringent effect is small, and if it is more than 1% by weight, the coloring of the cosmetic due to light and temperature becomes noticeable, which is not preferable.

The weight ratio of Odoricum extract to vitamin octahydrochloride is 1:100 to 100:1 (preferably 5:1 to 20:1).
). When the amount of vitamin B6 hydrochloride increases from 1:100, the coloring of cosmetics due to light and temperature due to vitamin octahydrochloride becomes noticeable, and when the amount of vitamin octahydrochloride decreases from 100:1, the astringent The effect of improving the effect is not fully exerted.

L-ascorbic acid used in the present invention is contained in citrus fruits and various raw vegetables as vitamin C, and has an antiscurvy effect.

It is also used as a melanin production inhibitor due to its strong reducing power. This is added in an amount of 0.001 to 1% by weight (preferably 0.05 to 0.00%) to a cosmetic containing 0.01 to 1% of the extract. 0.00
If it is less than 1% by weight, the effect will be poor, and if it is more than 1% by weight, the cosmetic will become noticeably colored by light and temperature, which is not preferable.

The weight ratio of Odoricum extract to L-ascorbic acid is 1:100 to 100:1 (preferably 5:1 to 20:
1). When the amount of ascorbic acid increases from 1:100, the coloring of cosmetics due to light and temperature caused by ascorbic acid becomes intense, and when the amount of ascorbic acid blended decreases from 100:1, the astringent effect of doriko grass improves. The effect is not fully exerted.

Note that when vitamin octahydrochloride and L-ascorbic acid are used together, the total amount of both may be adjusted to be the same as the amount of each used alone.

The same effect as using each alone can be obtained. In the skin astringent cosmetics according to the present invention, the astringent effect of Odoricum extract is combined with vitamin B6 hydrochloride and/or L-
The combination of a drug called ascorbic acid dramatically improves skin texture, improves the finish of makeup, prevents makeup from fading due to sweating, and reduces bleeding from small cuts after shaving. It is said to be a very useful skin astringent cosmetic because it has a suppressing effect, is safe for the skin, is also safe from light and temperature, and is resistant to deterioration such as discoloration even after long-term storage. can.

Next, the configuration and effects of the present invention will be explained in more detail by extracting some of the numerous experimental examples conducted by the present inventors.

Experimental Example 1
EXTRAITD″0RTIEBLANC1IE manufactured by E company
) Alone, e Odoricum extract + vitamin octahydrochloride 0.1
Weight %, f.
1% by weight, i. Odoricum extract + vitamin octahydrochloride 0.
05% by weight + 0.05% by weight of acorbic acid, g vitamin B6 hydrochloride alone, and HL-ascorbic acid alone were each dissolved in a 10% by weight aqueous solution of 95% ethanol, and the astringent effect of each was tested for protein cohesion with an albumin aqueous solution. Comparison was made by

The protein aggregation test using an aqueous albumin solution is commonly used in this industry and the pharmaceutical industry to measure the astringent action of various astringents (Fragrance ● Journal? 10 (1981), Kawaken Fine Chemical Co., Ltd. Pamphlet RPCA Armyo, Cape 12, Showa 5, manufactured by Co., Ltd.
Monthly issue, etc.)

(1) A 0.5% by weight albumin aqueous solution is uniformly stirred and dissolved. (2) Odoricum extract 011, 5, 1
0% by weight is weighed into each container, 0.1% by weight of the combined drug is added thereto, and the mixture is made up to 10 parts by weight with a 1% by weight aqueous solution of 95% ethanol.

(3) Weigh 1 part by weight of the adjustment solution in (1) and 4 parts by weight of the mixed solution in (2) in a test tube and mix.

(4) Measure the turbidity (white plate method) using an integrating sphere turbidity meter manufactured by Nippon Precision Engineering KK and use it as the protein cohesive force.

When the turbidity is high, the astringent effect is strong, and when the turbidity is low, the astringent effect is weak.

The results of these measurements are shown in FIG. The horizontal axis in Figure 1 is the blended amount (wt%) of Odoricum extract, vitamin B6 hydrochloride, or L-ascorbic acid, and the vertical axis is the blank (95% ethanol 1%) based on the actually measured turbidity value.
This is the value obtained by subtracting the turbidity of a 0.5% by weight aqueous albumin solution when only the nominal volume % aqueous solution is mixed. From Figure 1, the astringency is much higher in e1 when vitamin octahydrochloride is added, in f1 when ascorbic acid is added, and in case 1 when vitamin octahydrochloride + L-ascorbic acid is added than in d, which is the case of only Odoricum grass. It can be seen that the effect increases.

Experimental Example 2 Next, 20 adult women were asked about the skin cosmetics of the present invention.
We conducted tests on the skin astringent effect during application and the effect on preventing makeup from fading after application.

That is, an astringent lotion K containing 0.5% by weight of Adoricum extract and 0.1% by weight of vitamin B6 hydrochloride in the following normal astringent lotion formulation J for control, and 0.5 Astringent Lotion in j. Weight% and L
- Astringent lotion 1 containing 0.1% by weight of ascorbic acid was prepared, and j < 15k was given to a panel of 10 people, and j and 1 were given to another panel of 10 people for one week as usual. It was used in combination with makeup cosmetics and the results were compared. (Production method) Mix and dissolve (1), (2), (3), and (9) at room temperature.

This was also mixed and dissolved at room temperature (4), (5), (6)
), (7), and (8) to obtain a transparent lotion. (5), (6), (7), (
8) Dissolve in the aqueous phase in advance. The test results are shown in Table 1, and the results prove that the skin cosmetic of the present invention has an excellent astringent effect and is useful in preventing make-up from fading.

The scope of application of the present invention includes lotions, pre-cheap lotions, after-cheap lotions, hair tonics,
Water-alcohol based cosmetics such as emulsions and powdered lotions can be considered, but all of them are effective in tightening the skin, improving the finish of makeup, and preventing makeup from fading.

It also has an excellent hemostasis effect on small cuts when shaving. Next, examples of the present invention will be given.

Example 1 (Astringent lotion 1) (wt%) (
1) Ion exchange water 81.82 (2)
Dipropylene glycol 2.0 (3) Citric acid 0.03 (4) Sodium citrate 0.05 (5) Odoricum extract 0.3 (6) L-Ascorbic acid 0.05 (7) Denatured 95% ethanol 15.0(8) Methylvarapen
0.1(9)P. O. E. (15) Oleyl alcohol ether
0.5 (10) fragrance
0.1 ((1) UV inhibitor 0.0
5 (12) Pigment Appropriate amount (manufacturing method) (7), (8), (9), (10 mixed and dissolved at room temperature, (1), (2), (3), also mixed and dissolved at room temperature,
Add to (4), (5), (6), (11), and (12) with stirring.

Example 2 (Astringent lotion 2) (wt%) (
1) Ion exchange water 82.331 (2
) Dipropylene glycol 2.0 (3) Citric acid 0.03 (4) Sodium citrate 0.05 (5) Odoricum extract 0.3 (6) Vitamin octahydrochloride 0.05 (7) L-ascorbine Acid 0.05(8) Denatured 95% ethanol 15.0(9) P. O. E. (15) Oleyl alcohol ether
0.05 [phase] fragrance
0.1 (11 Rin external radiation absorber
0.05 (12) 8 elements Appropriate amount (manufacturing method) (8), (9), AO mixed and dissolved at room temperature, (1), (2), (3), (also mixed and dissolved at room temperature) 4),
Add to (5), (6), (7), (11), and (12) with stirring.

Example 3 (Aftershave lotion) (wt%) (
1) Ion exchange water 57.75 (2)
Glycerin 1.0 (3) Monobasic sodium phosphate 0.1 (4) Sodium citrate 0.1 (5) Allantoin
0.05(6) Odoricum extract
0.5(7) Vitamin octahydrochloride
0.2(8) Denatured 95% ethanol
40.0(9)P. O. E. (60) Hydrogenated castor oil adduct 0.5 (10) Ultraviolet absorber
0.05 (after 11) 0.1 (12) dye
Appropriate amount (manufacturing method) (9), (10, (11)) were mixed and dissolved at room temperature, and (1), (2), (3) (4) were also mixed and dissolved at room temperature.
, (5), (6), (7), (8), and (12) with stirring.

Example 4 (hair tonic) (wt%) (
1) Ion exchange water 37.89 (2)
PEG4OOl. O(3) hinokitiol
0.01(4) Odoricum extract
1.0 (5) Vitamin octahydrochloride 1.0
(6) Denatured 95% ethanol 60.0 (7
) POE hydrogenated castor oil adduct 0.5(8)e-
Menthol 0.05 (9) Ultraviolet absorber 0.1 (10) Fragrance
0.1 (11 Additives Appropriate amount (manufacturing method) (3), (6), (7), (8) were mixed and dissolved at room temperature, and (1), (2), ( 4)
, (5), (9), [phase], and (11) with stirring.

Example 5 (Aftershave cream) (wt%) (
1) Ion exchange water 85.07 (2)
PEG4OO2. O(3) glycerin
3.0(4) Allantoin
0.05(5) Odoricum extract 0
．． 2 (6) Vitamin octahydrochloride 0.5 (7
) Liquid paraffin 4.0 (8) Stearic acid 0.5 (9) Cetanol
2.0 (10) POE (25) Cetyl alcohol ether
2.0 (11) Glycerin monostearate 1.0 (12) Butylbarapen 0
．． 2(13)e-menthol 0.0
1 (14 sowing 0.1 (manufacturing method) (7), (8), (9), (10), (11), (12
), (13), and (14) were mixed and dissolved at 70°C, and (1), (2), (3), and (4) were also mixed and dissolved at 70°C.
), (5), and (6) with stirring to emulsify.

The emulsified particles are prepared using a homogenizer, and then cooled to room temperature using a heat exchanger. Example 6 (Powdered lotion) (wt%)
(1) Ion exchange water 91.59 (2
) Glycerin 1.0 (3) Odoricum extract 0.2 (4) L-ascorbic acid 0.05 (5) Denatured 95% ethanol 5.0 (6) Zinc white
1.5 (7) Kaolin
0.5(8)e-menthol
0.01(9) Methylvarapen
0.05 [Phase] Fragrance 0
．． 1 (Production method) After mixing and dissolving (1), (2), (3), and (4) at room temperature, (6) and (7) are added and stirred to disperse at room temperature.

(5), (8), (9) mixed and dissolved in this at room temperature
Stir and add.

[Brief explanation of the drawing]

FIG. 1 shows the results of a protein aggregation test of the present invention and a comparative example in Experimental Example 1. d...Odoriko grass extract, e...Odoriko grass extract vitamin octahydrochloride 0.1Wt%, f...
...Odoricum extract L-ascorbic acid 0.1Wt
%, g... Vitamin B6 hydrochloride, h...
-L-ascorbic acid, i...Odoricum extract Vitamin B6 hydrochloride 0.1wt% L-ascorbic acid 0.1wt%.

Claims (1)

[Claims] 1. A cosmetic product characterized by blending an extract of Odoricum and vitamin B6 hydrochloride and/or L-ascorbic acid.