JPS6335257B2 - - Google Patents

Description

Detailed Description of the Invention The present invention separates blood collected from a donor into physical components such as red blood cells, white blood cells, platelets, and liquid components such as plasma. This invention relates to a blood component reduction device for blood component transfusion, which extracts and supplies blood components and returns other excess blood components to the donor himself/herself.

Conventionally, in such blood component transfusions, for example,
When supplying only plasma from the blood collected from the donor to the recipient and returning other excess blood components to the donor himself/herself, a reduction device such as the one shown in Figure 1 is used. This is the most common method. That is, in FIG. 1, 1 is a blood sampling syringe needle, and 2 is a blood sampling bag having a blood component discharge tube 3 in the upper part, which is formed by polymerizing a flexible synthetic resin film and welding its periphery. This blood collection bag 2 is connected to a blood collection injection needle 1 and a blood collection tube 4. 5 is a plasma storage bag made of a transparent resin film similar to the blood collection bag 2, and this plasma storage bag 5 is similar to the blood collection bag 2.
and is connected by a plasma supply tube 6.

Reference numeral 7 denotes a filtration mixer for filtering and mixing blood components and physiological saline, which consists of a filtration tank 9 housing a net 8 therein and a mixing tank 10 arranged vertically in communication with each other. At the top, there is a blood component supply tube 13 having a blood component supply needle 12 attached to the tip 11 for connecting to the blood component discharge tube 3 provided at the top of the blood collection bag 2, and a physiological saline solution 15 at the tip 14. A physiological saline feed pipe 18 having a physiological saline feed needle 17 connected to the container body 16 containing the filtration mixer 7 is provided oppositely. A mixed liquid supply pipe 21 of mixed blood components and physiological saline 15 is provided, which communicates the part 19 with the blood collecting tube 4 through a branch pipe 20 disposed in the blood collecting tube 4. There is.

When blood components are reduced in blood component transfusion using the apparatus configured as described above, as shown in the figure, blood 23 is aspirated with the blood collection injection needle 1 inserted into the vein of the blood donor 22. is supplied into the blood collection bag 2 through the blood collection tube 4 to collect blood. Next, when a predetermined amount of blood has been collected, the blood collection tube 4 is closed at a certain width between the branch tube 20 and the blood collection bag 2, and the blood collection tube 4 is cut at this closed tube portion. Next, the blood collection bag 2 containing the blood 23 is
The plasma is passed through a centrifugal sedimentation machine in which the plasma storage bag 5 is connected with a plasma supply tube 6, as shown in FIG. Other blood components 25 consisting of the like are precipitated and separated into upper and lower parts. Next, by pressurizing and deforming the blood collection bag 2, only the separated and floated plasma 24 is transferred to the plasma supply tube 6.
After pressure-feeding the plasma through the blood collection bag 2 and the plasma storage bag 5, the plasma supply tube 6 is closed at a constant width between the blood collection bag 2 and the plasma storage bag 5, and the plasma supply tube 6 is cut at this closed tube portion.

Next, as shown in FIG. 3, the blood collection bag 2 containing the blood components 25 is inverted, and the blood component feeding needle 12 is press-fitted and connected to the blood component discharge pipe 3 provided at the top. , the blood component 25 is supplied to the filtration tank 9 of the filtration mixer 7 through the blood component supply pipe 13, and the physiological saline supply needle 17 is inserted into the container body 1.
Physiological saline 15 is supplied to the filtration tank 9 of the filtration mixer 7 through the saline supply pipe 18 connected to the filtration mixer 7. Then, there is a filter tank 9 in which a net 8 is stored.
The blood component 25 and physiological saline 15 that have passed through the filter are mixed inside the mixing tank 10 of the filtration mixer 7 to prevent coagulation of the blood component 25, and the mixed liquid is poured into the lower part of the filtration mixer 7. Excess plasma 24 is separated from the collected blood 23 by feeding it into the vein of the blood donor 22 through the branch pipe 20, blood collection tube 4, and blood collection injection needle 1 from the provided mixed liquid supply pipe 21. The blood component 25 is returned to the donor 22 itself.

According to the blood component reduction device for blood component transfusion as described above, when there is only one blood donor and
When operations such as centrifugation of collected blood and reduction of excess blood components are performed continuously, the donor's own excess blood components can be accurately returned to the donor and there is no room for problems. However, for example, when blood is collected from a large number of donors, as is the case when blood donors donate blood in groups, many blood collection bags containing the blood collected from these donors are simultaneously centrifuged and precipitated. When blood is centrifuged in a machine and then the separated and precipitated excess blood components are returned to individual blood donors, when centrifuging the collected blood, a blood collection syringe needle 1 and a blood collection bag 2 are used.
Because the blood collection tube 4 that connects the blood collection tube 4 must be cut, the name and blood type of the donor 22 are written on the surface of the blood collection bag 2 prior to blood collection, and the blood collection and centrifugation are performed. After the blood collection bag 2
Name and blood type written on the front of the blood donor 2
By checking the name and blood type of the person 2, the blood component feeding needle 12 is press-fitted into the blood component discharge pipe 3 of the blood collection bag 2, and the blood component 2 is collected.
5 must be returned to each donor 22 accurately, which is a cumbersome process, and even in this case, if multiple blood donors with similar names and blood types are In cases where there is a donor, if work such as verification of the donor's name and blood type is not carried out more carefully, blood components from other donors may be erroneously returned to the donor. Naturally, danger can occur.

The purpose of the present invention is to eliminate the drawbacks of the conventional reducing device, and it is an object of the present invention to provide a blood component discharging tube provided in a blood collection bag and a blood component supplying tube having a specified structure. By forming a connector that connects only in the case of a combination of blood collection bags and connecting the blood component discharge tube and blood component supply tube of the blood collection bag, and reducing the blood components through this connector, when blood is collected, It simplifies the process of reducing blood components by eliminating the need to write names and blood types on the surface of blood collection bags, and it also accurately returns the separated blood components collected from the donor to the donor. To provide a blood component reducing device for blood component transfusion, which can prevent blood components from being erroneously reduced by another person.

The blood component reduction device for blood component transfusion of the present invention is characterized by a blood collection bag 2 connected to a blood collection injection needle 1 and a blood collection tube 4 and having a blood component discharge tube 3 at the top thereof; 2 and a plasma storage bag 5 connected by a plasma supply pipe 6, a filter tank 9, and a mixing tank 10.
are arranged vertically in communication with each other, and at the top thereof there is a blood component supply pipe 13 for connecting to the blood component discharge pipe 3, and a physiological saline supply pipe connected to a container body 16 containing physiological saline 15. A mixed liquid supply tube 21 is provided opposite to the tube 18, and a mixed liquid supply tube 21 whose end 19 is connected to the blood sampling tube 4 via a branch tube 20 disposed in the conduit of the blood sampling tube 4 is provided at the bottom. A guide pin 2 is attached to the abutment surface 26 provided on the blood component discharge tube 3 of the blood collection bag 2.
7 and a male connector 28 having a blood component supply tube 1
a female connector 31 having a guide pin fitting hole 30 into which the guide pin 27 fits into an abutting surface 29 provided at the tip 11 of the male connector 2;
A virgin membrane 33 is provided on the end surface of the blood component discharge tube 3 provided at 8, and a male connector 28 is provided on the end surface of the blood component supply tube 13 provided with the female connector 31.
an abutting surface 26 provided with a guide pin 27 and an abutting surface 2 provided with a guide pin fitting hole 30 of a female connector 31;
9 and the virgin film 33 immediately before they come into close contact with each other.
In the case of a specified combination, a connecting nozzle pipe 34 with a sharpened tip is provided to penetrate into the blood component discharge pipe 3 through the blood component discharge pipe 3 and communicate the blood component discharge pipe 3 and the blood component supply pipe 13. Only in this case, the male connector 28 and the female connector 31 fit together to form a connector 32 that connects the blood component discharge tube 3 and the blood component supply tube 13.

Hereinafter, a preferred embodiment of the present invention will be described with reference to the drawings. FIGS. 4 to 7 show a reducing device of the present invention, which is installed in the blood component discharge pipe 3 of the blood collection bag 2 and guided to the abutting surface 26. Male connector 28 with pin 27
and a female connector 31 having a guide pin fitting hole 30 in which the guide pin 27 fits in an abutting surface 29 provided at the tip 11 of the blood component supply tube 13, and a male connector. A virgin membrane 33 is provided on the end surface of the blood component discharge tube 3 provided with the connector 28, and a guide pin 27 of the male connector 28 is provided on the end surface of the blood component supply tube 13 provided with the female connector 31. Immediately before the provided abutment surface 26 and the abutment surface 29 provided with the guide pin fitting hole 30 of the female type connector 31 come into close contact with each other, the blood component discharge tube 3 enters the blood component discharge tube 3 through the virgin membrane 33. , the male type connector 28 and the female type only in the case of a specified combination in which a connecting nozzle pipe 34 with a sharp tip for communicating the blood component discharge pipe 3 and the blood component supply pipe 13 is provided. A connector 32 that is fitted with the connector 31 and connects the blood component discharge pipe 3 and the blood component supply pipe 13.
has been formed.

In the illustrated embodiment, the combination of the male connector 28 and the female connector 31 of the connector 32 is made up of a guide pin 27 provided at an arbitrary position on the abutting surface 26 of the male connector 28, and a female connector 31. Although it is specified by a guide pin fitting hole 30 provided in the abutment surface 29 of the connecting tool 31 to correspond to the guide pin 27,
In this way, it is not necessarily necessary to provide the guide pin fitting hole 30 on the abutting surface 26 of the male connector 28 and the guide pin fitting hole 30 on the abutting surface 29 of the female connector 31, for example, A guide pin 27 and a guide pin fitting hole 30 are provided at arbitrary positions on the abutting surface 26 of the female connector 31, while a guide pin 27 and a guide pin fitting hole 30 are provided on the abutting surface 29 of the female connector 31. Accordingly, the male connector 28 and the female connector 31
It is also possible to specify the combination of guide pin 2.
7 and the guide pin fitting hole 30 provided to correspond to the guide pin 27, by varying the cross-sectional shape, length, position, number, etc. of the male connector 28 and the female connector 31. It is arbitrary to obtain a connector 32 with a specified combination of In contrast to the male type connector 28 and female type connector 31 of the specified combination of connectors 32 obtained by variously changing the position, number, etc., of the connector 32 of other specified combinations. When the male type connector 28 and the female type connector 31 are fitted, it is sufficient to make it impossible to fit them together so that the blood component discharge pipe 3 and the blood component supply pipe 13 do not communicate with each other. As shown in the figure, a guide groove 36 is provided inside the ring wall 35 of the male connector 28, and a guide key 38 that fits into the guide groove 36 is provided on the outer peripheral surface 37 of the female connector 31. Accordingly, the guide pin 27 provided on the abutting surface 26 of the male connector 28 and the guide pin fitting hole 30 provided on the abutting surface 29 of the female connector 31 may be easily aligned.

Next, to explain the blood collection and the reduction of excess blood components according to the present invention, as shown in FIG. 4 to the blood collection bag 2 for blood collection. Next, when a predetermined amount of blood has been collected, the blood collection tube 4 is closed at a certain width between the branch tube 20 and the blood collection bag 2, and the blood collection tube 4 is cut at this closed tube portion. Next, the blood collection bag 2 containing the blood 23 is passed through a centrifugal sedimentation machine in which a plasma storage bag 5 is connected with a plasma supply tube 6, to float the plasma 24, which has a light specific gravity, in the collected blood 23, and to float the plasma 24, which has a heavy specific gravity. Other blood components 25 consisting of red blood cells, white blood cells, platelets, etc. are precipitated and separated into upper and lower parts (see FIG. 2). Next, by deforming the blood collection bag 2 under pressure, only the separated and floated plasma 24 is fed under pressure to the plasma storage bag 5 through the plasma supply pipe 6.
The plasma supply tube 6 is closed at a constant width between the blood collection bag 2 and the plasma storage bag 5, and the plasma supply tube 6 is cut at this closed tube portion.

Next, as shown in FIG. 5, the blood collection bag 2 containing the blood component 25 is inverted, and as shown in FIGS.
As shown in the figure, the male connector 28 provided on the blood component discharge tube 3 and the female connector 31 provided at the tip 11 of the blood component supply tube 13 are fitted together, and the blood components in the blood collection bag 2 are connected. The discharge pipe 3 and the plasma supply pipe 6 are communicated with each other to supply the blood component 25 of the blood collection bag 2 to the filtration tank 9 of the filtration mixer 7, and the physiological saline supply needle 1
Physiological saline supply pipe 1 connecting 7 to the container body 16
Physiological saline 15 is supplied through 8 to the filtration layer 9 of the filtration mixer 7 . Then, the blood component 25 that has passed through the filter layer 9 containing the net 8 therein and the physiological saline 15 are mixed inside the mixing tank 10 of the filtration mixer 7 to prevent the blood component 25 from coagulating. ,
Blood is collected by feeding this mixed solution into the vein of the blood donor 22 from the mixed solution supply pipe 21 provided at the lower part of the filtration mixer 7 through the branch pipe 20, the blood collection tube 4, and the blood collection injection needle 1. Plasma 2 from blood 23
The excess blood component 25 from which 4 has been separated is returned to the blood donor 22 itself.

In this way, the present invention allows the blood component discharge tube and the tip of the blood component supply tube provided in the blood collection bag to be fitted together only in a specified combination, and to be connected to the blood component discharge tube of the blood collection bag. Since a connector is formed to communicate with the blood component supply tube, after blood is collected from a large number of blood donors, a large number of blood collection bags containing the blood collected from these donors are simultaneously placed in a centrifugal sedimentation machine for centrifugal separation of the blood. Even in cases where only plasma is separated and extracted, and then the separated and precipitated excess blood components are returned to individual blood donors, as in the past, prior to blood collection, the donor's blood is placed on the surface of the blood collection bag. By filling in the name and blood type, etc., and carefully checking the donor's name and blood type, etc., with the name and blood type displayed on the blood collection bag when returning blood components. Blood components can be reliably returned to a blood donor while preventing erroneous return of blood components, without requiring the trouble of returning the blood components to the donor himself/herself.

Therefore, according to the present invention, the blood component transfusion work can be simplified, so that the blood component transfusion work can be carried out efficiently, and the excess blood components collected and separated from the blood donor himself can be accurately returned to the donor. Since the risk of erroneously returning blood components of another person to a blood donor can be prevented, the blood components can be safely and reliably returned in blood component transfusion.

[Brief explanation of the drawing]

Figure 1 is a cutaway front view of a blood component reduction device in conventional blood component transfusion, Figure 2 is a front view of a blood collection bag and plasma storage bag showing the state of blood separation in the same as above, and Figure 3 is a front view of blood components in the same as above. FIG. 4 is a partially cutaway front view showing the connected state of the discharge tube and the blood component supply tube. FIG. 4 is a partially cutaway front view of the blood component reduction device in component transfusion of the present invention. FIG. 5 is the blood component discharge according to the present invention. A cutaway side view showing the state of communication between the tube and the blood component supply tube, FIG. 6 is an enlarged sectional view taken along line A-A in FIG. 5, and FIG. 7 is a male connector and a female connector. FIG. 8 is an enlarged front view of the male connector, and FIG. 9 is an enlarged front view of the female connector. 1... Blood sampling needle, 2... Blood sampling bag, 3...
Blood component discharge tube, 4... Blood collection tube, 5... Plasma storage bag, 6... Plasma supply tube, 7... Filtration mixer, 9
...Filter layer, 10...Mixing tank, 11...Tip, 1
3... Blood component supply tube, 15... Physiological saline, 1
6... Container body, 18... Physiological saline supply pipe, 19
... end, 20 ... branch pipe, 21 ... mixed liquid supply pipe, 26 ... abutment surface, 27 ... guide pin, 28
...Male type connector, 29...Abutting surface, 30...Guide pin fitting hole, 31...Female type connector, 32...Connector, 33...Virgin membrane, 34...Connection nozzle pipe.

Claims (1)

[Claims] 1 A blood collection bag 2 having a blood component discharge tube 3 on the upper part connected by a blood collection injection needle 1 and a blood collection tube 4, a plasma storage bag 5 connected to the blood collection bag 2 and a plasma supply tube 6, and a filtration bag 2. The tank 9 and the mixing tank 10 are arranged vertically in communication with each other, and the upper part thereof is connected to a blood component supply pipe 13 for connecting to the blood component discharge pipe 3 and a container body 16 containing physiological saline 15. A physiological saline supply pipe 18 is disposed opposite to the pipe 18, and an end portion 1 is provided at the bottom.
A mixed liquid supply pipe 21 is connected to the blood collection tube 4 through a branch pipe 20 which is arranged in the blood collection tube 4.
A male connector 28 having a guide pin 27 on the abutment surface 26 provided on the blood component discharge pipe 3 of the blood collection bag 2, and a blood component supply A female connector 31 having a guide pin fitting hole 30 into which the guide pin 27 fits into an abutment surface 29 provided at the tip 11 of the tube 13, and a blood component provided in the male connector 28. A virgin membrane 33 is provided on the end surface of the discharge pipe 3, and a blood component supply pipe 13 is provided with a female connector 31.
The guide pin 27 of the male connector 28 is attached to the end surface of the tube.
Immediately before the abutment surface 26 provided with the guide pin fitting hole 30 of the female connector 31 comes into close contact with each other, the abutment surface 26 enters the blood component discharge tube 3 through the virgin membrane 33, Only in the case of a specified combination in which a connecting nozzle pipe 34 with a sharpened tip for communicating the blood component discharge pipe 3 and the blood component supply pipe 13 is provided, the male connector 28 and the female connector are connected. A connector 32 that is fitted with the fitting 31 and connects the blood component discharge pipe 3 and the blood component supply pipe 13.
A blood component reduction device for blood component transfusion formed by forming a blood component.