JPH0346239B2 - - Google Patents

Description

Detailed Description of the Invention (Field of Industrial Application) The present invention relates to a rotary core tablet machine that compresses and molds powder to cover a core tablet to form a core tablet for pharmaceuticals, etc. The present invention relates to a method for detecting the position of a core lock that automatically detects the presence and position of a core lock previously supplied to the mortar hole.

(Prior art) Generally, in order to manufacture dry-coated tablets used for pharmaceuticals, etc., a first powder is placed in a large number of dies arranged on a rotary disk, and then a core tablet is placed on top of the powder. The core tablet is placed on the core tablet by a feeding device, and then the second powder is filled from above, and then compressed with an upper punch and a lower punch to obtain a core tablet as a molded product.

Conventionally, it has been impossible to detect the position in the mortar at which the core tablet is fed, and even non-core tablets to which the core tablet is not fed, during the operation of the tablet machine. After taking out the product, the dry-coated tablet, from the tablet machine, either conduct a destructive inspection of the dry-coated tablet to confirm the position of the cored tablet, or check all the tablets to determine whether there are any non-coated tablets, based on weight differences, etc. It is necessary to sort the core locks, and no one has been developed that allows the position of the core lock placed in the mortar by the feeding device to be detected even during operation.

(Problems to be Solved by the Invention) In a core tablet used for medicine, etc., the core tablet and the surrounding tablet portion are made of different types of drugs, and when the core tablet is taken, two or more locations in the body may be affected. However, in a rotary dry-coated tablet machine that produces dry-coated tablets, the core tablet must be fed into the mortar of a rotary disc that rotates at high speed. The core locks are held in advance in a disk having a large number of holes that synchronize with the disk, and the core locks are dropped one by one from above the mortar.

However, if the rotary core tablet machine stops, the core tablet will fly out of the hole in the disc due to inertia, and this is because a detector etc. can be used to confirm that the core tablet is held in the hole in the disc in advance. This may occur even after the tablet has been processed, and there is a risk that the tablet may be treated as a normal tablet even though the tablet has not actually been fed into the mortar.

In addition, due to scratches on the core tablet, surface condition (such as when the surface is coated with a film, etc.), or changes in the powder properties (such as fine powder or granules), the timing of supply of the core tablet may be disrupted, or the core tablet may not be supplied onto the powder. As the core tablet slips, etc., the supply position is distorted, so the core tablet is not located in the center of the core tablet, and the product core tablet easily cracks, and it becomes difficult to take the tablet. When the core tablet is eccentric, the temporal changes that occur in the body become unstable. There was an important problem in the manufacturing control of dry-coated tablets, which required the detection of

(Means for Solving the Problems) In order to solve such problems, the configuration of the present invention is such that a first mortar hole is provided in the mortar hole of the mortar 2 disposed on the rotary disk 1.
A core tablet 7 is placed on top of the powder 5a by a core tablet supply device 6, and a second powder 5b is filled so as to cover the core tablet 7. In a rotary dry-coated tablet machine that produces a dry-coated tablet by compressing it with a punch 3, a cored tablet 7 is placed on top of the first powder 5a.
After placing the powder and before filling the second powder 5b, a multi-optical axis color-coded sensor 20 that illuminates the inside of the mortar hole of the mortar 2 is installed, and the color-coded sensor 20 The position of the core tablet in the rotary core tablet machine is characterized in that the core tablet position in the mortar hole is detected by detecting the color difference between the powder 5a and the core tablet 7 at a plurality of locations in the mortar hole. This is a detection method.

(effect) The above technical means works as follows.

The core tablet 7 is supplied to the mortar 2 containing the first powder 5a, that is, it is placed on the powder 5a, and then the second powder 5a is placed on top of the powder 5a.
The turntable 1 rotates to supply b,
At a position before the second powder 5b is supplied, the color difference between the powder 5a and the core tablet 7 is detected at multiple locations by a multi-optical axis color sensor 20 that illuminates the inside of the mortar hole of the mortar 2 at multiple locations. For example, as shown in FIG.
If the optical axes of the O direction sensor C and the S direction sensor D have a predetermined color difference between the powder 5a and the core tablet 7, it is recognized as normal. If the lock 7 is eccentric in the direction of the arrow R or the direction of the arrow S, the respective sensors A,
Since the color difference detected by B or sensors C and D changes, the color difference is recognized, stored, displayed, etc., and if it is determined to be defective, it is discharged as a defective product different from the good core tablet. It is something.

Furthermore, if each sensor A, B, C,
If none of D detects a color difference between the powder 5a and the core tablet 7, the tablet is recognized as a non-core tablet and is discharged as a defective product separately from the core tablet, which is a good product as described above.

Note that the color-coded sensor 20 is synchronized with the rotating mortar 2, and the color-coded sensor 20 is synchronized with the rotating mortar 2.
Even if the powders put into the mortar 2 are of the same color, the powder compressed into the core tablet 7 will be a little darker in color, so the color difference can be instantly detected.

(Embodiment) An embodiment of the present invention will be described with reference to the drawings. Reference numeral 1 is a rotary disk on which a large number of dies 2 are arranged at equal intervals on the circumference.

6 is a core lock supply device synchronized with the rotary disk 1 for dropping and supplying the core lock 7 into the hole of the mortar 2;
The core lock supply device 6 holds the core lock 7 sent from the feeder 12 through the feeding pipe 13 in advance in the hole of the disc, and detects that the core lock 7 is held. It is detected by the lock detection phototube 16, and if the core lock 7 is not held, the position of the mortar 2 that becomes the coreless lock is determined by storing the signals from the timing phototube 15 and the timing hole 14. is memorized, and the coreless tablet is taken out to the coreless tablet chute 23 by the removal damper 18.

5a is the first powder put into the hole of the mortar 2, and the powder 5a falls from the powder outlet 19,
A fixed amount is fed into the mortar 2 by the first feed system 4 .

5b is a second powder that is filled by the second feeder 8 after the first powder 5a enters the hole of the mortar 2, and then the core tablet 7 is supplied.

3 is the lower pestle, 17 is the upper pestle, 9 is the lower pestle 3 and the upper pestle 17
This is a compression roll for compressing from above and below.

Reference numeral 11 denotes a dry-coated tablet which is normally molded with a core tablet 7, and the dry-coated tablet 11 is taken out of the rotary disk 1 by a damper 10 and a chute 21 and falls into a receiving can 22.

20 is a multi-optical axis color-coded sensor disposed at a position after the core tablet 7 is supplied until the second powder is filled, and the color-coded sensor 20 receives a plurality of color-coded signals. a detection unit 20b that transmits and receives signals, a control unit 20a that amplifies and controls each signal, and four arrow R direction sensors A, L direction sensors B, O direction sensors C, and S direction sensors D. Fiber part 20c that irradiates signals
and a stabilized power supply 20d.

Reference numeral 25 denotes a storage device for storing defective or good products such as non-nucleated tablets or eccentric cored tablets of the nuclear tablet 7 detected and recognized by the color-coded sensor 20; Of course, it is intended to display and record the degree to which the core lock 7 is eccentric.

The color-coded sensor 20 is normally used for the mortar 2 of the turntable 1.
The first powder 5a is put into the hole, and then the core tablet 7 is fed into the mortar 2, which is placed on top of the powder 5a by the core tablet supply device 6. , B, C, and D irradiate,
Detecting color differences between the powder 5a and the core tablet 7 at four locations,
If it is recognized that the core lock 7 is normally supplied as shown in FIG. 3, it is taken out by the damper 10 through the chute 21 into the receiving can 22 as a good product.

If the core lock 7 is eccentric from the predetermined position as shown in Figures 4 and 5, or if it is a coreless lock,
The color difference of each of the above-mentioned sensors A, B, C, and D changes, and for example, when the core lock 7 is eccentric in the direction of the arrow R as shown in FIG. 4, the sensor A detects more colors of the core lock 7. Therefore, the amount of eccentricity of the core tablet 7 is recognized based on the detected amount of color difference, and if it exceeds a predetermined amount, it is judged as defective, and each sensor A, B,
When C and D are recognized as non-nuclear tablets that do not detect color difference, the solenoid 24 connected to the storage device 25 operates, and the exclusion damper 1
8, and the non-nuclear lock chute 23 is rejected as a defective product.
This is the one that is removed from the rotary disk 1.

(Effects of the Invention) As explained above, the present invention allows the core lock to be directly fed into the mortar using a multi-optical axis color sensor after the feeding process. By detecting the presence and location of core tablets, it is possible to determine whether the tablet is good or defective. Not only can non-core tablets be completely eliminated, but core tablets that are defective can also be completely eliminated. It can be eliminated, and there is no need for any other sorting equipment for non-coated tablets or destructive inspection of the product, and defective non-coated tablets or eccentric cored tablets are mixed into good cored tablets. This has the advantage that quality control, which is important due to the nature of dry-coated tablets used in medicines, etc., can be easily carried out.

[Brief explanation of drawings]

The drawings show a method for detecting the position of a core tablet in a rotary core tablet machine according to the present invention, and FIG. 1 is a plan view, and FIG. 2 is a state inside the mortar when a normal core tablet is manufactured. Cross-sectional diagrams, Figures 3 and 4 to explain the
FIG. 5 is an enlarged plan view of the main part for explaining the detection state of the color-based sensor. In the drawings, 1 is a rotary disk, 2 is a mortar, 3 is a lower pestle, 4 is a first feedstock, 5a and 5b are powder,
6 is a core tablet feeding device, 7 is a core tablet, 8 is a second feed, 9 is a compression roll, 10 is a damper, 11 is a core tablet, 12 is a feeder, 13 is a feeding pipe,
14 is a timing hole, 15 is a timing photocell,
16 is a core lock detection phototube, 17 is an upper punch, 18 is an exclusion damper, 19 is a powder dropper, 20 is a color-coded sensor, 20a is a control section, 20b is a detection section, 20c is a fiber section, 20d is a stabilizing power source, 21 is a chute, 22 is a receiving can, 23 is a non-nuclear tablet chute, 24
2 is a solenoid, and 25 is a storage device.

Claims (1)

[Claims] 1 Put the first powder 5a into the mortar hole of the mortar 2 disposed on the rotary disk 1, and place the core tablet supply device 6 on top of the powder 5a.
A rotary type cored tablet for manufacturing a cored tablet by placing the tablet 7 thereon, filling the second powder 5b so as to cover the cored tablet 7, and then compressing it with an upper punch 17 and a lower punch 3. In the tablet machine, after placing the core tablet 7 on the first powder 5a and before filling the second powder 5b,
A color-coded sensor 20 with a multi-hole shaft that illuminates the inside of the mortar hole of the mortar 2 is arranged, and the color-coded sensor 20 illuminates the inside of the mortar hole of the mortar 2.
Detecting the position of a core tablet in a rotary core tablet machine, characterized in that the core tablet position in the mortar hole is detected by detecting color differences between the powder 5a and the tablet 7 at a plurality of locations in the mortar hole. Method.