JPH0246274B2 - - Google Patents
Info
- Publication number
- JPH0246274B2 JPH0246274B2 JP59146299A JP14629984A JPH0246274B2 JP H0246274 B2 JPH0246274 B2 JP H0246274B2 JP 59146299 A JP59146299 A JP 59146299A JP 14629984 A JP14629984 A JP 14629984A JP H0246274 B2 JPH0246274 B2 JP H0246274B2
- Authority
- JP
- Japan
- Prior art keywords
- tablet
- core
- powder
- core tablet
- mortar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000843 powder Substances 0.000 claims description 34
- 239000004570 mortar (masonry) Substances 0.000 claims description 23
- 239000003814 drug Substances 0.000 description 5
- 238000001514 detection method Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 230000007717 exclusion Effects 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 230000001360 synchronised effect Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
- B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
- B30B15/32—Discharging presses
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Sorting Of Articles (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Glanulating (AREA)
Description
【発明の詳細な説明】
(産業上の利用分野)
この発明は、核錠の有無を判別して無核錠剤を
完全に排除することができる医薬等の有核錠剤を
製造する回転式有核錠剤機に関するものである。Detailed Description of the Invention (Field of Industrial Application) This invention is a rotary cored tablet for producing cored tablets for pharmaceuticals, etc., which can determine the presence or absence of cored tablets and completely eliminate non-core tablets. It concerns tablet machines.
(従来の技術)
一般に、医薬等に用いる有核錠剤を製造するに
は、回転盤に多数配設された臼の中に、第1の粉
末を入れ、次にその粉末の上に核錠が核錠供給装
置により載置され、その核錠の上から更に第2の
粉末を充填した後、上杵と下杵とにより圧縮され
て成形品である有核錠剤を得るものである。(Prior art) Generally, in order to manufacture dry-coated tablets used for pharmaceuticals, etc., a first powder is placed in a number of dies arranged on a rotary disk, and then a cored tablet is placed on top of the powder. The core tablet is placed by a core tablet supply device, and after the second powder is further filled on top of the core tablet, it is compressed by an upper punch and a lower punch to obtain a core tablet as a molded product.
従来、この核錠が臼の中に供給されたというこ
とは全く確認できなかつたもので、もし確認しよ
うとすれば、製品である有核錠剤を錠剤機から取
り出した後、その全数を重量差等により、無核錠
ないことを選別しなければならず、また、その核
錠は小さくなる傾向にあり、重量差等の選別は不
可能となるものであり、臼の中に載置された核錠
を直接確認できる本発明は有効なものである。 In the past, it was impossible to confirm that the core tablets were fed into the mortar at all. Therefore, it is necessary to sort out whether there is a non-core tablet or not, and since the core tablet tends to be small, it is impossible to sort out the difference in weight, etc. The present invention, which allows the core tablet to be directly confirmed, is effective.
(発明が解決しようとする問題点)
医薬等に用いる有核錠剤は、その核錠と周りの
錠剤部とは異種の薬剤から形成されており、それ
を服用した場合に体内の2個所以上において作用
するものであるが、その有核錠剤を製造する回転
式有核錠剤機においては、高速で回転する回転盤
の臼の中に核錠を供給しなければならず、その方
法としては、回転盤と同期する多数の孔を有する
円板に予め核錠を保持しておき、臼の上方よりそ
の核錠を1個づつ落し込むようになつている。(Problems to be Solved by the Invention) In a core tablet used for medicine, etc., the core tablet and the surrounding tablet portion are made of different types of drugs, and when the core tablet is taken, two or more locations in the body may be affected. However, in a rotary dry-coated tablet machine that produces dry-coated tablets, the core tablet must be fed into the mortar of a rotary disc that rotates at high speed. The core locks are held in advance in a disk having a large number of holes that synchronize with the disk, and the core locks are dropped one by one from above the mortar.
しかしながら、その回転式有核錠剤機が停止し
た場合には慣性により核錠が円板の孔より飛び出
し、これは、円板の孔に核錠が予め保持されてい
ることを検出器等で確認した後においても起りう
るものであり、実際に核錠が臼の中に供給されて
いないにも係わらず正常な有核錠剤であると処理
される恐れがある。 However, if the rotary core tablet machine stops, the core tablet will fly out of the hole in the disc due to inertia, and this is because a detector etc. can be used to confirm that the core tablet is held in the hole in the disc in advance. This may occur even after the tablet has been processed, and there is a risk that the tablet may be treated as a normal tablet even though the tablet has not actually been fed into the mortar.
また、核錠の傷や静電気の影響の為に、予め円
板に供給された核錠が、正常に臼の中に供給され
ず、即ち全く供給されなかつたり、供給するタイ
ミングが狂い核錠が破壊されて飛び出してしまう
ものであり、このような核錠が入つていない無核
錠が製品である有核錠剤の中に混入することは、
その有核錠剤の性質上絶無にしなければならない
という問題があつた。 In addition, due to scratches on the core lock or the influence of static electricity, the core lock that has been supplied to the disk in advance may not be fed into the mortar properly, that is, it may not be fed at all, or the timing of feeding may be incorrect and the core lock may be It is something that can be broken and thrown out, and if such a non-core tablet that does not contain a core tablet gets mixed into the product with a cored tablet,
Due to the nature of the dry-coated tablet, there was a problem that it had to be completely eliminated.
(問題点を解決するための手段)
このような問題を解決するために、この発明の
構成は、回転盤1に配設された臼2の臼孔に、第
1の粉末5aを入れ、該粉末5aの上に核錠7を
載置し、該核錠7を被うように第2の粉末5bを
充填した後、上杵17と下杵3とにより圧縮して
有核錠剤11を製造する回転式有核錠剤機におい
て、第1の粉末5aの上に核錠7を載置した後、
第2の粉末5bを充填するまでの間に色別センサ
ー20を配設し、該色別センサー20で粉末5a
と核錠7の色差を検出することにより核錠7の有
無を判別して無核錠剤を排除するようにした事を
特徴とする回転式有核錠剤機である。(Means for Solving the Problems) In order to solve such problems, the configuration of the present invention is such that the first powder 5a is put into the mortar hole of the mortar 2 disposed on the rotary disk 1, A core tablet 7 is placed on top of the powder 5a, and the second powder 5b is filled so as to cover the core tablet 7, and then compressed with an upper punch 17 and a lower punch 3 to produce a core tablet 11. After placing the core tablet 7 on the first powder 5a in the rotary core tablet machine,
A color-specific sensor 20 is provided before filling the second powder 5b, and the color-specific sensor 20 detects the powder 5a.
This is a rotary tablet machine with a core, which is characterized in that the presence or absence of a core tablet 7 is determined by detecting the color difference between the core tablet 7 and the core tablet 7, and non-core tablets are rejected.
(作用) 上記の技術的手段は次の様に作用する。(effect) The above technical means works as follows.
第1の粉末5aが入つた臼2に核錠7が供給即
ち載置され、次に第2の粉末5bを供給すべく回
転盤1は回転するのであるが、その第2の粉末5
bが供給される前の位置において、粉末5aと核
錠7の色の差を色別センサー20によつて判別
し、所定の色差を有すれば正常と認識し、もし核
錠が載置されていなければ、その色差を有しない
ので無核錠と認識記憶して、良品である有核錠剤
とは別に不良品として排出するものである。 The core tablet 7 is supplied or placed on the mortar 2 containing the first powder 5a, and then the turntable 1 rotates to supply the second powder 5b.
At the position before the powder b is supplied, the color difference between the powder 5a and the core tablet 7 is determined by the color sensor 20, and if there is a predetermined color difference, it is recognized as normal. If not, the tablet is recognized as a non-coated tablet because it does not have that color difference, and is discharged as a defective product separately from the good tablets with a core.
なお、色別センサー20は、回転する臼2と同
期しており、たとえ核錠7に使用された粉末と第
1に臼2の中に入れられる粉末が同色であつたと
しても、核錠7に打錠されたものは少し濃い色と
なる為に、その色差を瞬間的に検知し得るもので
ある。 Note that the color-coded sensor 20 is synchronized with the rotating mortar 2, and even if the powder used for the core tablet 7 and the powder first put into the mortar 2 are of the same color, the core tablet 7 The tablets compressed into tablets have a slightly darker color, so the color difference can be instantly detected.
(実施例)
この発明の一実施例を図面について説明すれ
ば、1は円周上に臼2が等間隔に多数配設された
回転盤である。(Embodiment) An embodiment of the present invention will be described with reference to the drawings. Reference numeral 1 is a rotary disk on which a large number of dies 2 are arranged at equal intervals on the circumference.
6は核錠7を臼2の孔中に落し込んで供給する
ための回転盤1と同調する核錠供給円板であり、
該核錠供給円板6は、その孔中にフイダー12か
ら給送パイプ13を通つて送られてくる核錠7を
予め保持しておき、核錠7が保持されていること
を核錠検知光電管16により検出し、もし、この
核錠7が保持されていない場合には、タイミング
光電管15とタイミング孔14とによる信号が記
憶されることにより、この無核錠となる臼2の位
置が記憶され、無核錠剤は排除ダンパー18によ
り無核錠シユート23に取り出される。 6 is a core lock supply disc that is synchronized with the rotary disk 1 for dropping and supplying the core lock 7 into the hole of the mortar 2;
The core lock supply disk 6 holds in advance the core lock 7 sent from the feeder 12 through the feed pipe 13 in its hole, and detects that the core lock 7 is held. It is detected by the phototube 16, and if the core lock 7 is not held, the position of the mortar 2 that becomes the coreless lock is memorized by storing the signals from the timing phototube 15 and the timing hole 14. The coreless tablet is taken out into the coreless tablet chute 23 by the removal damper 18.
5aは臼2の孔中に入れられる第1の粉末であ
り、該粉末5aは、粉末落し口19より落下し、
第1フイドシユ4により定量を臼2の中に供給さ
れる。 5a is the first powder put into the hole of the mortar 2, and the powder 5a falls from the powder outlet 19,
A fixed amount is fed into the mortar 2 by the first feeder 4 .
5bは、臼2の孔中に上記第1の粉末5aが入
り、次に、核錠7が供給された後、第2フイドシ
ユ8により充填される第2の粉末である。 5b is a second powder that is filled by the second powder 8 after the first powder 5a enters the hole of the mortar 2 and the core tablet 7 is supplied.
3は下杵、17は上杵、9は下杵3と上杵17
を上下より圧縮する為の圧縮ロールである。 3 is the lower pestle, 17 is the upper pestle, 9 is the lower pestle 3 and the upper pestle 17
This is a compression roll for compressing from above and below.
11は正常に核錠7を有して成形された有核錠
剤であり、該有核錠剤11は、ダンパー10、シ
ユート21により回転盤1の外に取り出され受缶
22の中に落下する。 Reference numeral 11 denotes a dry-coated tablet which is normally molded with a core tablet 7. The dry-coated tablet 11 is taken out of the rotary disk 1 by a damper 10 and a chute 21 and falls into a receiving can 22.
20は核錠7が供給された後第2の粉末が充填
されるまでの間の位置に配設された色別センサー
であり、該色別センサー20は、色別信号を発信
し受信する検出部20bと、その信号を増幅した
り制御をおこなう制御部20aと、信号を照射す
るフアイバー部20cと、安定化電源20dとか
ら成るものである。 Reference numeral 20 denotes a color-coded sensor disposed at a position after the core tablet 7 is supplied until the second powder is filled, and the color-coded sensor 20 is a detection sensor that transmits and receives color-coded signals. 20b, a control section 20a that amplifies and controls the signal, a fiber section 20c that irradiates the signal, and a stabilized power source 20d.
この色別センサー20は、通常回転盤1の臼2
の孔に第1の粉末5aが入れられ、次に核錠7が
核錠供給円板6によりその粉末5aの上に供給即
ち載置された臼2の中を色別信号が照射すること
により、その粉末5aと核錠7との色差を受けて
判別し、核錠7が供給されていることを認識し、
もし、核錠7が載置されていない場合は、色差が
ないので核錠7が供給されていないと判別し、記
憶装置25に記憶させる。 This color-coded sensor 20 normally
The first powder 5a is put into the hole, and then the core tablet 7 is supplied by the core tablet supply disk 6, i.e., the inside of the mortar 2 is placed on top of the powder 5a. , discriminates based on the color difference between the powder 5a and the core tablet 7, and recognizes that the core tablet 7 is supplied;
If the core lock 7 is not placed, it is determined that the core lock 7 is not being supplied since there is no color difference, and this is stored in the storage device 25.
そして、この無核錠は、上記記憶装置25に接
続されたソレノイド24が作動することにより、
排除ダンパー18を作動させ、無核錠シユート2
3で回転盤1外に排除される。 This coreless lock is activated by the operation of the solenoid 24 connected to the storage device 25.
Activate the exclusion damper 18 and release the lockless lock shoot 2.
3, it is removed from the rotary disk 1.
(発明の効果)
以上に説明したように、本発明は、核錠が回転
盤の臼の中に供給されるその供給工程後に、色別
センサーによつて直接その臼の中を検知して核錠
の有無を判別し得るものであり、無核錠を完全に
排除できるので、他に無核錠と有核錠剤の選別装
置も必要なく、無核錠が有核錠剤の中に混入する
ことの全くないという医薬等に用いられる有核錠
剤の性質上重要な品質管理ができる等の効果を有
するものである。(Effects of the Invention) As explained above, the present invention is capable of directly detecting the inside of the mortar using a color-coded sensor after the feeding process in which the core lock is fed into the mortar of the rotary disk. It is possible to determine the presence or absence of a tablet, and it can completely eliminate non-coated tablets, so there is no need for any other device to separate non-coated tablets from non-coated tablets, and non-coated tablets can be mixed into coated tablets. This has the effect of enabling quality control, which is important due to the nature of dry-coated tablets used in medicine, etc., which are completely free of oxidation.
図面はこの発明による回転式有核錠剤機を示す
ものであり、第1図は平面図、第2図は正常に有
核錠剤が製造される場合の臼の中の状態等を説明
する断面図、第3図は不良品である無核錠が製造
される場合の臼の中の状態等を説明する断面図で
ある。
図面において、1は回転盤、2は臼、3は下
杵、4は第1フイドシユ、5a,5bは粉末、6
は核錠供給円板、7は核錠、8は第2フイドシ
ユ、9は圧縮ロール、10はダンパー、11は有
核錠剤、12はフイダー、13は給送パイプ、1
4はタイミング孔、15はタイミング光電管、1
6は核錠検知光電管、17は上杵、18は排除ダ
ンパー、19は粉末落し口、20は色別センサ
ー、20aは制御部、20bは検出部、20cは
フアイバー部、20dは安定化電源、21はシユ
ート、22は受缶、23は無核錠シユート、24
はソレノイド、25は記憶装置を示すものであ
る。
The drawings show a rotary dry-coated tablet machine according to the present invention, and FIG. 1 is a plan view, and FIG. 2 is a cross-sectional view illustrating the state inside the mortar when normally producing dry-coated tablets. , FIG. 3 is a sectional view illustrating the state inside the mortar when defective coreless tablets are manufactured. In the drawings, 1 is a rotary disk, 2 is a mortar, 3 is a lower punch, 4 is a first feeder, 5a and 5b are powders, and 6
1 is a core tablet supply disc, 7 is a core tablet, 8 is a second feed, 9 is a compression roll, 10 is a damper, 11 is a core tablet, 12 is a feeder, 13 is a feeding pipe, 1
4 is a timing hole, 15 is a timing photocell, 1
6 is a core lock detection phototube, 17 is an upper punch, 18 is an exclusion damper, 19 is a powder dropper, 20 is a color-coded sensor, 20a is a control section, 20b is a detection section, 20c is a fiber section, 20d is a stabilizing power source, 21 is a chute, 22 is a receiving can, 23 is a non-nuclear tablet chute, 24
2 is a solenoid, and 25 is a storage device.
Claims (1)
粉末5aを入れ、該粉末5aの上に核錠7を載置
し、該核錠7を被うように第2の粉末5bを充填
した後、上杵17と下杵3とにより圧縮して有核
錠剤11を製造する回転式有核錠剤機において、
第1の粉末5aの上に核錠7を載置した後、第2
の粉末5bを充填するまでの間に色別センサー2
0を配設し、該色別センサー20で粉末5aと核
錠7の色差を検出することにより核錠7の有無を
判別して無核錠剤を排除するようにした事を特徴
とする回転式有核錠剤機。1 Put the first powder 5a into the mortar hole of the mortar 2 disposed on the rotary disk 1, place the core tablet 7 on top of the powder 5a, and place the second powder so as to cover the core tablet 7. In a rotary dry-coated tablet machine that produces a dry-coated tablet 11 by compressing it with an upper punch 17 and a lower punch 3 after filling the powder 5b,
After placing the core tablet 7 on the first powder 5a, the second
Before filling the powder 5b, the color-coded sensor 2
The rotary type is characterized in that the presence or absence of the core tablet 7 is determined by detecting the color difference between the powder 5a and the core tablet 7 with the color-specific sensor 20, and the non-core tablets are excluded. Core tablet machine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14629984A JPS6125559A (en) | 1984-07-13 | 1984-07-13 | Nucleus tablet detector of rotary type nucleus provided tablet pressing machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14629984A JPS6125559A (en) | 1984-07-13 | 1984-07-13 | Nucleus tablet detector of rotary type nucleus provided tablet pressing machine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6125559A JPS6125559A (en) | 1986-02-04 |
| JPH0246274B2 true JPH0246274B2 (en) | 1990-10-15 |
Family
ID=15404535
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP14629984A Granted JPS6125559A (en) | 1984-07-13 | 1984-07-13 | Nucleus tablet detector of rotary type nucleus provided tablet pressing machine |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6125559A (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2802054B2 (en) * | 1996-02-06 | 1998-09-21 | 株式会社菊水製作所 | Rotary nucleated tablet machine |
| TWI690333B (en) * | 2015-06-29 | 2020-04-11 | 日商大賽璐股份有限公司 | Manufacturing method of easy-to-take solid preparation (with nuclear ingot) and easy-to-take solid preparation |
-
1984
- 1984-07-13 JP JP14629984A patent/JPS6125559A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6125559A (en) | 1986-02-04 |
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