JPH0635144B2 - Infusion container manufacturing method - Google Patents
Infusion container manufacturing methodInfo
- Publication number
- JPH0635144B2 JPH0635144B2 JP2239555A JP23955590A JPH0635144B2 JP H0635144 B2 JPH0635144 B2 JP H0635144B2 JP 2239555 A JP2239555 A JP 2239555A JP 23955590 A JP23955590 A JP 23955590A JP H0635144 B2 JPH0635144 B2 JP H0635144B2
- Authority
- JP
- Japan
- Prior art keywords
- synthetic resin
- thermoplastic synthetic
- parison
- present
- liquid storage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Landscapes
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Blow-Moulding Or Thermoforming Of Plastics Or The Like (AREA)
Description
本発明は輸液容器の製造方法に関するものである。更に
詳しくは複数の薬液を臨床で用いられる場合に適当とさ
れる一体化した容器（以下、マルチバツクという）の製
造方法に関するものである。The present invention relates to a method for manufacturing an infusion container. More specifically, the present invention relates to a method for producing an integrated container (hereinafter referred to as a multi bag) that is suitable when a plurality of liquid medicines are clinically used.
第３図は現行マルチバツグの説明図である。 一般にマルチバツグは周縁部４で袋状に仕上げられた上
下に継合する２個の液体収納部１，２にアミノ酸又は葡
萄糖などの薬液，すなわち，輸液が各々収納され，これ
を吊下部５を利用してスタンド（図示されてない）など
から患者に輸液を注入するために用いられるものであ
る。 このように使用されるマルチバツグは軟質熱可塑性合成
樹脂で作られている。そして上下にポート３と３′（液
体を容器に充填したり，容器から排出するとき用いられ
る口をポートという）を有し下方のポート３′だけから
液体収納部１の輸液も液体収納部２の輸液と共に患者に
注入できるように液体流通部６がもうけられてある。 この液体流通部６は患者に薬液を注入するまでは流体が
連通してはならないので熱融着性フイルム７を挿入し，
その部分を熱圧着しておく方法が見受けられるようにな
った。その場合は，使用にあたり薬液の充填された液体
収納部１や２を手で押し熱融着性フイルム７を剥離させ
流体を連通させて使用するものである。FIG. 3 is an explanatory diagram of the current multi-bag. In general, multi-bags are stored in a bag-like shape at the peripheral portion 4 and are joined in two liquid storage parts 1 and 2 that are vertically joined to each other, and liquid chemicals such as amino acids or glucose, that is, infusion liquids are stored in each of them, and the suspension 5 is used. It is used to inject an infusion solution into a patient from a stand (not shown) or the like. The multi-bag used in this way is made of a soft thermoplastic synthetic resin. The upper and lower ports 3 and 3 '(ports used to fill and discharge the liquid from the container are called ports) are provided and only the lower port 3'can be used for infusion of the liquid storage unit 1 as well. A liquid circulation part 6 is provided so that it can be injected into a patient together with the infusion solution. Since the fluid must not be in communication with the liquid circulation portion 6 until the medical fluid is injected into the patient, the heat-fusible film 7 is inserted.
It has become possible to find a method of thermocompression bonding that part. In that case, in use, the liquid storage parts 1 and 2 filled with a chemical solution are manually pushed to separate the heat-fusible film 7 and the fluid is used for communication.
このようなマルチバツグを作るには，フイルムを得るこ
と・バツグ用に裁断すること・製袋のための熱プレス及
び冷プレス・熱融着性フイルムの挿入・ポート投入・ポ
ート部溶着・仕上げのための最終的熱プレス及び冷プレ
ス・薬液充填・ポート部溶着という連綿たる工程を経る
ことになる。 本発明は製袋・薬液充填・ポート部溶着という簡単な工
程だけでマルチバツグを作ることが目的である。To make such a multi-bag, obtain the film, cut it for the bag, hot press and cold press for bag making, insert the heat-fusible film, insert the port, weld the port, and finish. The final hot press and cold press, chemical filling, and port welding will be repeated. An object of the present invention is to produce a multi bag by only simple steps of bag making, filling with a chemical solution, and welding of a port portion.
本発明は，軟質の熱可塑性合成樹脂と該合成樹脂とは異
なる第２の熱可塑性合成樹脂とを共押出しして，内層の
一部に第２の熱可塑性合成樹脂が存在するようにパリソ
ンを形成し，次いで該パリソンをブロー成形してパリソ
ンの軸方向に継合部をはさんで２個の液体収納部を直列
に形成するとともに，この２個の液体収納部のそれぞれ
にポートを突設させ，前記継合部を流体が連通しないよ
うに熱圧着することを特徴とする輸液容器の製造方法を
要旨とする。 本発明を図面を用いて詳しく説明する。 第１図は本発明のパリソンの斜視図であり，第２図は本
発明製造方法の輸液容器の説明図である。 本発明において，パリソン本体11は主として軟質の熱可
塑性合成樹脂からなるが，この素材としては，100℃以
上の高温での加熱殺菌処理に耐えるもので医用に現在使
用されている軟質熱可塑性合成樹脂を指し，ポリ塩化ビ
ニル・ポリプロピレン・ポリエチレン・ポリプロピレン
−ポリエチレンの共重合物などをあげることができる。 本発明において，２個の液体収納部１及び２を作るのは
アミノ酸又は葡萄糖などの薬液をおのおの別々に収納さ
せるためである。また，液体収納部１及び２の継合部13
に対向して，おのおのにポート３と３′を突設させるの
は薬液を投入するためと臨床で使用するときに排出する
ために当然必要とするものである。 本発明において継合部13は，２個の液体収納部１と２に
充填される２種の薬液が臨床で使用されるまでは全く混
じり合わないように，第２図の点線で示す第２の熱可塑
性合成樹脂を介して流体が連通しないように熱圧着され
ている。しかし，マルチバツグを臨床で使用する場合，
継合部13を連通させるために薬液が充填された液体収納
部１や２を手でおしつけ，第２の熱可塑性合成樹脂を継
合部13の内部で剥離させ，両薬液が混じり合って使用さ
れる。このようにマルチバツグの２種の薬液が臨床で使
用されるまでは全く混じり合わないで，臨床で使用する
場合，継合部13が連通するための接着性は，ほどよいも
のでなければならない。この適度の接着性は剥離方法で
評価すれば30〜250g/cmの値が好ましい。 上記のようなマルチバツグを得るために，本発明におい
て，該パリソンから２個の液体収納部が上記第２の熱可
塑性合成樹脂の存在部分を継合部13としてパリソンの軸
方向に直列にブロー成形により作られ，継合部13を流体
が連通しないように熱圧着する。この熱圧着条件は使用
する樹脂により決められるが，例えば，軟質熱可塑性合
成樹脂をポリエチレンとし，第２の熱可塑性合成樹脂を
ポリプロピレンとした場合，温度を180〜250℃，時間を
３〜５秒の条件にするのが好ましい。 その第２の熱可塑性合成樹脂としては，医療用用途であ
ることを考慮してポリエチレン・ポリプロピレンのよう
なポリオレフイン系樹脂が好ましい。そして上記の適度
の接着性を得るために，本発明におけるパリソンの素材
は軟質の熱可塑性合成樹脂を主とし，それとは異種の第
２の熱可塑性合成樹脂とからなる複合素材にするのであ
る。 また，複合素材のパリソンにおいて第２の熱可塑性合成
樹脂12の投入量は継合部13を連通させたときの口の大き
さと関係し，少なくとも連通部の巾の分だけは必要であ
る。 本発明のように，複合素材のパリソンを共押出しで作る
のは周知の方法でよい。例えば，二つのエクストルーダ
を用い，軟質熱可塑性合成樹脂のパリソン本体の押出し
中に，第２の熱可塑性合成樹脂を連続して注入すると得
られる。 なお本発明のマルチバツグは２個の液体収納部を上下に
連ねたもので，これらの継合部13は臨床で使用されるま
では熱融着されたままであるが，この部分にクリツプな
どで熱融着部分の剥離を防止しておくことも好ましいこ
とである。 以上のように本発明で作られたマルチバツグは液体収納
部１と２に薬液が充填され，各ポート部の溶着がなされ
る。必要なれば継合部13にクランプを念入りに付けて使
用までの両薬液間の連通を防止しておくこともある。In the present invention, a soft thermoplastic synthetic resin and a second thermoplastic synthetic resin different from the synthetic resin are co-extruded to form a parison so that the second thermoplastic synthetic resin is present in a part of the inner layer. After forming the parison, the parison is blow-molded to form two liquid storage parts in series with a joint part in the axial direction of the parison, and a port is provided on each of the two liquid storage parts. A method of manufacturing an infusion container is characterized in that the joint is thermocompression-bonded so that fluid is not communicated. The present invention will be described in detail with reference to the drawings. FIG. 1 is a perspective view of a parison of the present invention, and FIG. 2 is an explanatory view of an infusion container of the manufacturing method of the present invention. In the present invention, the parison body 11 is mainly made of a soft thermoplastic synthetic resin, and as the material, a soft thermoplastic synthetic resin that is resistant to heat sterilization treatment at a high temperature of 100 ° C. or more and is currently used for medical purposes is used. And polyvinyl chloride / polypropylene / polyethylene / polypropylene / polyethylene copolymers and the like. In the present invention, the reason why the two liquid storage parts 1 and 2 are made is to store the chemical liquid such as amino acid or glucose individually. In addition, the joint portion 13 of the liquid storage portions 1 and 2
It is of course necessary to project the ports 3 and 3 ′ facing each other in order to inject the drug solution and to discharge the drug solution in clinical use. In the present invention, the joint portion 13 is the second portion shown by the dotted line in FIG. 2 so that the two kinds of liquid medicines filled in the two liquid storage portions 1 and 2 do not mix at all until clinical use. Are thermocompression bonded so that fluids do not communicate with each other via the thermoplastic synthetic resin. However, when clinically using multi-bag,
In order to connect the joints 13, the liquid storage parts 1 and 2 filled with the chemicals are put on by hand, the second thermoplastic synthetic resin is peeled off inside the joints 13, and both chemicals are mixed and used. To be done. As described above, the two types of multi-bug drug solutions do not mix at all until clinical use, and when used clinically, the adhesiveness for the joint portion 13 to communicate with each other must be appropriate. This moderate adhesiveness is preferably 30 to 250 g / cm when evaluated by a peeling method. In order to obtain the multi-bag as described above, in the present invention, two liquid storage parts from the parison are blow-molded in series in the axial direction of the parison using the existing part of the second thermoplastic synthetic resin as the joint part 13. The joint 13 is thermocompression-bonded so that the fluid does not communicate. The thermocompression bonding conditions are determined depending on the resin used. For example, when the soft thermoplastic synthetic resin is polyethylene and the second thermoplastic synthetic resin is polypropylene, the temperature is 180 to 250 ° C and the time is 3 to 5 seconds. It is preferable that the condition As the second thermoplastic synthetic resin, a polyolefin resin such as polyethylene / polypropylene is preferable in view of its medical use. In order to obtain the above-described appropriate adhesiveness, the material of the parison in the present invention is a soft thermoplastic synthetic resin as a main component and a composite material composed of a second thermoplastic synthetic resin different from the soft thermoplastic synthetic resin. In addition, in the parison of the composite material, the input amount of the second thermoplastic synthetic resin 12 is related to the size of the mouth when the joining portion 13 is communicated, and at least the width of the communicating portion is necessary. Coextrusion of the composite parison, as in the present invention, may be accomplished by well known methods. For example, it is obtained by using two extruders and continuously injecting the second thermoplastic synthetic resin during extrusion of the parison body of the soft thermoplastic synthetic resin. In the multi-bag of the present invention, two liquid storage parts are connected in a vertical direction, and the joint part 13 remains heat-sealed until clinically used, but this part is heated by a clip or the like. It is also preferable to prevent peeling of the fused portion. As described above, in the multi-bag made according to the present invention, the liquid storage portions 1 and 2 are filled with the chemical liquid, and the respective port portions are welded. If necessary, a clamp may be carefully attached to the joint portion 13 to prevent communication between both chemical liquids until use.
本発明によれば，マルチバツグの製造方法が製袋・薬液
充填・ポート部溶着だけの工程であるので，従来の製造
方法に比し簡単な工程だけでマルチバツグを作ることに
なる。According to the present invention, since the manufacturing method of the multi-bag is only the steps of bag making, filling with the chemical liquid, and welding of the port portion, the multi-bag is manufactured by a simpler process than the conventional manufacturing method.
第１図は本発明のパリソンの斜視図であり，第２図は本
発明の輸液容器の説明図である。 第３図は現行マルチバツグの説明図である。 １及び２……液体収納部、３と３′……ポート、４……
周縁部、５……吊下部、６……液体流通部、７……熱融
着性フイルム、11……パリソン本体、12……第２の熱可
塑性合成樹脂、13……継合部。FIG. 1 is a perspective view of a parison of the present invention, and FIG. 2 is an explanatory view of an infusion container of the present invention. FIG. 3 is an explanatory diagram of the current multi-bag. 1 and 2 ... Liquid storage part, 3 and 3 '... Port, 4 ...
Peripheral part, 5 ... Hanging part, 6 ... Liquid distribution part, 7 ... Thermal fusion film, 11 ... Parison body, 12 ... Second thermoplastic synthetic resin, 13 ... Splicing part.
Claims (1)
異なる第２の熱可塑性合成樹脂とを共押出しして，内層
の一部に第２の熱可塑性合成樹脂が存在するようにパリ
ソンを形成し，次いで該パリソンをブロー成形してパリ
ソンの軸方向に継合部をはさんで２個の液体収納部を直
列に形成するとともに，この２個の液体収納部のそれぞ
れにポートを突設させ，前記継合部を流体が連通しない
ように熱圧着することを特徴とする輸液容器の製造方
法。1. A parison such that a soft thermoplastic synthetic resin and a second thermoplastic synthetic resin different from the synthetic resin are coextruded so that the second thermoplastic synthetic resin is present in a part of the inner layer. Then, the parison is blow-molded, and two liquid storage parts are formed in series with the joint part in the axial direction of the parison, and a port is projected in each of the two liquid storage parts. A method for manufacturing an infusion container, wherein the joint portion is thermocompression-bonded so that fluid is not communicated.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2239555A JPH0635144B2 (en) | 1990-09-10 | 1990-09-10 | Infusion container manufacturing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2239555A JPH0635144B2 (en) | 1990-09-10 | 1990-09-10 | Infusion container manufacturing method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH04118216A JPH04118216A (en) | 1992-04-20 |
| JPH0635144B2 true JPH0635144B2 (en) | 1994-05-11 |
Family
ID=17046546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2239555A Expired - Lifetime JPH0635144B2 (en) | 1990-09-10 | 1990-09-10 | Infusion container manufacturing method |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0635144B2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2570071B2 (en) * | 1992-09-01 | 1997-01-08 | 東洋製罐株式会社 | Multilayer container with light-transmitting window, method for producing the same, and multilayer coextrusion apparatus |
-
1990
- 1990-09-10 JP JP2239555A patent/JPH0635144B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH04118216A (en) | 1992-04-20 |
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