JPH0637385B2 - Patch - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial field of application] The present invention relates to a patch, and more specifically, to a human body using a base fabric having equal stretchability in each direction (isotropic stretchability) as a base fabric portion. The present invention relates to a patch having excellent adhesiveness.

[Conventional technology]

The patch is generally widely used as a poultice for stiff shoulders, low back pain, bruise, sprains and the like. The composition generally consists of a base cloth part and a plaster part, and depending on the type of the plaster part, a drug such as methyl salicylate or menthol is used as a gelatin, sodium polyacrylate, a water-soluble polymer such as sodium alginate or the like. It is roughly classified into mineral powders such as titanium oxide, a patching agent kneaded with water, and a plastering agent that uses various gums as an adhesive instead of the water-soluble polymer. A cloth, a non-woven fabric, a polypropylene sheet, or the like is used as a base cloth for holding these plasters, and the above-mentioned plasters are applied to the base cloth to obtain a product.

[Problems to be solved by the invention]

However, although the plaster itself used for conventional patches is generally stretchable, the cloth, non-woven fabric, polypropylene sheet and other base fabrics holding it are lacking in stretchability. For this reason, when it is applied to the human body, the movement of the human body does not allow the base cloth to be synchronized, resulting in the peeling of the patch.
This phenomenon is more prominent in places where the movement of the human body is strong, such as joints.

Generally, such peeling is considered to be caused by insufficient adhesive force of the plaster, and various studies have been made on increasing the adhesive force of the plaster. However, in this way of thinking, there is a limit to the improvement in adhesive strength of the plaster, and if the adhesiveness is too strong, it will cause a feeling of tightness such as tightness and pain at the application site, and it will still be sufficiently satisfactory. I could not find the patch.

On the other hand, as a means for preventing such peeling, it has been devised to use a flexible material for the base cloth (Japanese Patent Laid-Open No. 57-57,572).
-42617, JP-A-57-181010), all of these were limited to a base fabric that stretches in only one direction or a base fabric that only stretches in the vertical and horizontal directions. It was limited, and the base cloth could not follow the movement of the skin and was peeled off at a site where the movement of the joint and the like was strong and the stretch and contraction occurred in both vertical and horizontal directions.

As described above, it has been earnestly desired to develop a patch that is difficult to peel off when applied to any part of the human body and has a good feeling in use.

[Means for solving problems]

Therefore, as a result of repeated studies to solve such problems, the present inventors have found that a base fabric having specific isotropic stretchability and a specific shrinkability in a direction orthogonal to the stretch direction. With the use of a specific plaster as a plaster part, it has sufficient adhesiveness to the human body even when using a plaster that was conventionally said to have insufficient adhesive strength, and has a feeling of use. The present invention has been completed by discovering that

That is, the present invention is a patch having a base cloth part and a plaster part, wherein the load when the base cloth part stretches the base cloth to 120% is 1 to 50 g / cm, and the load is 150% in one direction. It is an isotropic stretchable blended nonwoven fabric composed of thermoplastic fibers and non-thermoplastic fibers whose shrinkage in a direction forming 90 degrees with it is 50% or less, and the paste part is a polyacrylic acid alkali metal in the paste. It is intended to provide a patch comprising a salt, a copolymer of maleic anhydride and another monomer, and polybutene, and having an adhesive force of No. 4 or more of the pole tack method of the paste.

The requirements for the isotropic stretchable base fabric used in the patch of the present invention are found from the present inventors' study on the stretch and contraction of the skin of each part of the human body as shown in Reference Example 1 below. That is, among the various parts of the human body, the neck, shoulders, elbows, fingers,
It has high elasticity in the flank, knees, ankles, etc., and the maximum expansion and contraction rate of these parts is 1.4 of the original length (natural state).
It is about double. Therefore, in order to be able to follow the expansion and contraction of each part of the human body, the expansion / contraction ratio of the base cloth does not need to be doubled or tripled, but at least about 1.5 times. Then, it is desirable that the load (stress) for stretching to a length of 1.5 times the original length which is the maximum elongation should take a value as small as possible. Not only is it hardly felt, but it is also possible to follow the intense movements of the skin, and peeling is less likely to occur. On the other hand, in flexion and extension of joints such as elbows and knees, the length extends about 1.4 times and the width also extends 1.1 to 1.3 times. However, the base cloth generally used for the patch is expanded in one direction and contracted in the other direction. If this shrinkage ratio is large, the patch that has been stuck a long time may be peeled off in the shrinking direction, or a tight feeling may occur.

From the above facts, the base fabric used in the present invention is
Isotropic stretchability, 120% of the base cloth
The load when expanding and contracting is 1 to 50 g / cm, preferably 1
-30g / cm, and when one direction expands and contracts to 150%, the contraction in the direction that makes 90 degrees with it is 50% or less,
It is preferably 30% or less. If this shrinkage exceeds 50%, the base fabric cannot follow the movement of the skin,
It may cause peeling. Further, it is more preferable that the latter load is 1 to 100 g / cm when the base fabric is expanded and contracted in one direction by 150% and is expanded by 120% in a direction forming 90 degrees with it. The load when the above-mentioned base cloth is stretched may be measured, for example, by cutting the base cloth into 15 × 7 cm and extending the length 10 cm to a predetermined length with a tensilon meter.

The non-woven fabric used in the present invention is made by blending thermoplastic fibers and non-thermoplastic fibers, and especially thermoplastic fibers 50 to 9
It is preferably a blended yarn of 0% by weight and 10 to 50% by weight of non-thermoplastic fiber.

Examples of the thermoplastic fiber include polyester fiber, polyamide fiber, polyvinyl chloride fiber, polyvinyl alcohol fiber, polyethylene fiber, polypropylene fiber and the like, and these may be used alone or in combination of two or more. Non-thermoplastic fibers include rayon, hemp, silk,
Examples include Kyupra.

The method for producing a non-woven fabric using these fibers is not particularly limited, for example, a method of bonding with a binder, a method of imparting good strength by heat bonding, a method of entanglement of fibers by water needling to improve elasticity. It is preferable to use the method of holding.

In the plaster part of the patch of the present invention, a plaster conventionally used,
For example, a water-soluble polymer, a mineral powder, or a mixture of the medicinal component and water can be applied, but the plaster preferably has elasticity similar to that of the base cloth. However, in reality, it is difficult to make the plaster and the base cloth have the same elasticity, and it is acceptable if the expansion rate of the plaster is equal to or higher than the expansion rate of the base cloth. However, when the stretchability of the plaster and the stretchability of the base cloth are significantly different, if the adhesiveness between the paste and the base cloth is insufficient, peeling between the base cloth and the paste occurs, or when the paste is applied to the skin. It is not preferable because only the plaster remains on the surface.
Therefore, in the present invention, in order not to cause such a defect, as a paste, a paste containing a polyacrylic acid alkali metal salt such as sodium polyacrylate, a copolymer of maleic anhydride and another monomer, and polybutene. The body is used. As the other monomer copolymerized with maleic anhydride, vinyl monomers, particularly vinyl acetate, methoxyethylene and the like are preferable. In the paste, an alkali metal salt of polyacrylic acid is 1 to 10% by weight (hereinafter simply abbreviated as%), a copolymer of maleic anhydride and another monomer is 0.5 to 10%, and polybutene is 0. It is preferable to contain 5 to 10%.

In addition, a plaster having a strong adhesive force is generally required to prevent peeling, but in the present invention, a strong adhesive force is not particularly required, and a ball tack method of No. 4 or more is sufficient.

The patch of the present invention can be produced by applying the plaster to the above-mentioned base fabric according to a method known per se.

〔The invention's effect〕

The patch of the present invention can follow the movement of a human body even when it is attached to a site where the body moves rapidly, and has good adhesiveness and usability. Further, since the adhesiveness is increased, the release of the medicinal component from the plaster is improved and the therapeutic effect can be enhanced.

〔Example〕

 Next, the present invention will be described with reference to Reference Examples and Examples.

Reference Example We examined the expansion and contraction of the skin in each part of the human body. When the adult stomach (height: 165 to 175 cm) is flexed and stretched to the maximum in various directions for each of the 10 necks, shoulders, elbows, wrists, index fingers, back, flank, knees, calves, and ankles. The length changed to was measured. The results are shown in Table-1. The expansion rate in the table was obtained according to the following formula. In the formula, the original length means the length of the natural state.

Example 1 (1) 3D × 65 mm polyester and 3D × 51 mm rayon were made into a random wave with a basis weight of 70 g / m ² at a ratio of 70:30, and heat treated at about 200 ° C. and a moving speed of 3 m / min. An isotropic stretchable nonwoven fabric was obtained. This non-woven fabric has a thickness of 2.5 to 3.5 mm.
The sample was cut into a size of 7 cm in width and 7 cm in width, and a 10 cm lengthwise portion was stretched to 120% with a tensilon meter (manufactured by Toyo Baldwin Co., Ltd.) to obtain a load of 7 g / cm. Similarly, when the longitudinal 10 cm portion is expanded to 150%, the transverse contraction is 15%, and at the same time the transverse 5 cm portion is 1%.
The load when stretched by 20% was 21 g / cm.

The non-woven fabric was coated with a paste having the following composition so as to be 1100 g / m ² to obtain a stretchable patch agent (product 1 of the present invention).

Paste composition: Menthol 2 (wt%) Methyl salicylate 2 Glycol salicylate 1 Sodium polyacrylate 3 (0.2% aqueous solution viscosity: 400-600 cps) Polyacrylic acid 3 (40% aqueous solution viscosity: 100-300 cps) Glycerin 20 Aluminum hydroxide 0.3 Polysorbate 80 1 Carboxymethyl cellulose 0.5 Sodium alginate 0.5 Methoxyethylene-maleic anhydride copolymer 5 (Average degree of polymerization about 140) Polybutene 2.5 (Average molecular weight 1350) Water balance (2 ) (coated so that 1100 g / cm ² to the non-stretchable nonwoven or knitted a plaster obtained in 1) was prepared Comparative product 1 and 2. This comparative product and the product 1 of the present invention obtained in (1) were attached to the shoulders, elbows, backs, knees, and ankles of five healthy males, and the flexion and extension movements of each site were performed, and the number of times until peeling occurred was measured. . As a result, as shown in Table 2, the patch of the present invention had extremely excellent adhesiveness.

Example 2 (1) 60: 20: 2 3D × 51 mm polyester, 3D × 51 mm vinylon and 3D × 40 mm Kyupra
A random wave having a basis weight of 70 g / m ² was prepared at a ratio of 0 and heat-treated at about 200 ° C. at a moving speed of 3 m / min to obtain an isotropic stretchable nonwoven fabric. This non-woven fabric has a thickness of 3.0 to 3.5 mm, and when the load during expansion and contraction of the non-woven fabric was measured by the same method as in Example 1, the load at 120% elongation in the longitudinal direction was 8.5 g / cm. Atsuta The vertical direction is 15
The contraction in the transverse direction was 20% when stretched to 0%, and the latter load was 23 g / cm when stretched to 150% in the longitudinal direction and 120% in the transverse direction.

The non-woven fabric was coated with a paste having the following composition so as to be 1100 g / m ² to obtain a stretchable patch agent (Product 2 of the present invention).

Plaster composition: Menthol 1.5
(Wt%) methyl salicylate 2 glycol salicylate 1 sodium polyacrylate 2.5 (viscosity of 0.2% aqueous solution: 400 to 600 cps) polyacrylic acid 2.5 (viscosity of 40% aqueous solution: 100 to 300 cps glycerin 20 hydroxylation Aluminum 0.3 Polysorbate 1.5 Carboxymethylcellulose 0.5 Methoxyethylene-maleic anhydride copolymer 5 (Average degree of polymerization about 140) Polybutene 3 (Average molecular weight 1350) Water balance (2) As a plaster, the plaster of (1) A stretchable patch agent (each of the present invention or 4) is obtained in the same manner as in (1) except that a composition obtained by removing polybutene from the body composition or a composition obtained by removing methoxyethylene-maleic anhydride copolymer is used. As a result of performing an adhesive force test on these patches with the ball tack method (JIS), the product 2 of the present invention was No. .6, product 3 of the present invention
Was No. 5 and the product 4 of the present invention was No. 6.

These patches were affixed to the elbows of five healthy males, and bending and stretching exercises were performed to examine the adhesiveness in the same manner as in Example 1. Note that not only the adhesiveness between the skin and the patch but also the adhesiveness between the base cloth and the plaster was examined. As a result, as shown in Table 3, the products 2 to 4 of the present invention were all excellent in adhesiveness, but the product 2 of the present invention had the most favorable properties as a patch.

Claims (1)

[Claims] 1. A patch having a base cloth part and a plaster part, wherein the load when the base cloth part stretches the base cloth to 120% is 1 to 50 g / cm, and the load is 150% in one direction. It is an isotropic stretchable blended nonwoven fabric composed of thermoplastic fibers and non-thermoplastic fibers whose shrinkage in a direction forming 90 degrees with it is 50% or less, and the paste part is a polyacrylic acid alkali metal in the paste. An adhesive patch comprising a salt, a copolymer of maleic anhydride and another monomer, and polybutene, and having a ball tack adhesive strength of No. 4 or more of the plaster.