JPH0653157B2 - Blood sampling device for measuring blood sampling weight - Google Patents

Description

TECHNICAL FIELD The present invention relates to a blood collecting apparatus for measuring the weight of collected blood.

[Prior Art] Conventionally, a blood collecting device as described in Japanese Patent Publication No. 51-3153 has been proposed. A conventional blood collection device stores a blood bag in a blood collection chamber, detects by a limit switch that the thickness of the blood bag that expands with blood collection reaches a predetermined level, and stops the blood collection operation based on this detection result, As a result, a predetermined amount of blood is collected in the blood bag.

Further, in the conventional blood collecting device, the blood bag tray is swung during blood collection into the blood bag, whereby the blood and the anticoagulant such as heparin preloaded in the blood bag are stirred. This prevents blood from coagulating.

[Problems to be Solved by the Invention] However, in the above-described conventional blood collection device, the blood collection amount is measured when the thickness of the blood bag reaches a certain level, and therefore the measurement accuracy is poor.

Therefore, in order to improve the measurement accuracy of the blood collection amount, it is possible to measure the blood collection amount by measuring the weight change of the blood bag during blood collection. However, at this time, when the blood bag and its pan are placed on the weight measuring means while rocking the blood bag being collected to agitate the anticoagulant and blood, the blood bag and its pan are shaken. The load state of these loads on the weight measuring means changes depending on the dynamic angle position, and stable measurement of the weight of collected blood cannot be performed.

It is an object of the present invention to stably improve the accuracy of measuring the amount of blood collected when collecting blood while rocking the blood container to prevent blood coagulation.

[Means for Solving the Problem] The present invention according to claim 1 provides a container support part for supporting a blood container, a swinging means for rocking the container support part during blood collection into the blood container, and a blood collecting process. In the blood collecting device having a weight measuring means for measuring the weight of blood collected in the blood container in, the measurement result of the weight measuring means in a state where the container supporting part is at the turning point of the swinging process by the swinging means. A control means for taking in and obtaining the amount of blood collected or the amount of blood collected in the blood container based on the measurement result is provided.

According to a second aspect of the present invention, in addition to the first aspect of the present invention, the container support portion is at a turning point of a swinging process by the swinging means at least at a stage of ending blood collection into the blood container. When the measurement result of the weight measuring means is taken in, the swinging operation of the container support portion by the swinging means is temporarily stopped.

[Operation] The inventor of the present invention, at the stage before establishing the present invention, "when collecting blood while rocking the blood container, in order to stabilize the measurement accuracy of the blood collection amount, rock the container support part by the rocking means. In the state of temporarily stopping at an intermediate position sandwiched between the upper and lower turning points of the process, the measurement result of the weight measuring means is taken and the weight of the blood container is determined based on this measurement result. "

However, as a result of the experimental study by the inventor, the inventor found that
The inventors of the present invention have found that the blood collecting device based on the above-mentioned idea has the following disadvantages.

Since the container support is suddenly decelerated and stopped during the intermediate swinging process, the blood in the container is greatly shaken, which makes it difficult to perform accurate weight measurement.

Since the container support portion is temporarily stopped during the swinging intermediate process, insufficient mixing of the anticoagulant and blood in the container is caused.

Then, the inventor of the present invention has completed the present invention as described above which can solve the above inconvenience.

That is, according to the present invention described in claim 1, it is possible to collect blood while rocking the blood container by the rocking means, and to measure the weight of the blood sample when the solution container is at the turning point of the rocking process. Become. Therefore, there are the following actions (1) and (2).

(1) The weight of the collected blood is measured when the container support part has the least swaying motion (the turning point above or below the oscillating process or in the vicinity thereof), and the swaying of the blood in the container is minimized. Accurate weight measurement is possible because the measurement is performed at a certain timing.

(2) Since the container support is not temporarily stopped in the intermediate process of rocking, the anticoagulant in the container and blood can be mixed well in the rocking process and blood coagulation can be prevented.

Further, according to the present invention as set forth in claim 2, at least at the end stage of blood collection, the container support portion is at the turning point of swinging,
When taking in the measurement result of the weight measuring means, the swinging operation by the swinging means is temporarily stopped. Therefore,
It has the function of (3).

(3) The weight of the collected blood is measured while the container support is gently stopped, and the shaking caused by the blood in the container is calmed. .

[Embodiment] FIG. 1 is a front view showing a blood collecting device according to an embodiment of the present invention, FIG. 2 is a side view showing a main portion of FIG.
1 is a plan view of FIG. 1, FIG. 4 is a side view showing a scale, FIG. 5 is a vacuum circuit diagram, FIG. 6 is a rocking state diagram, and FIG. 7 is a control block diagram.

As shown in FIGS. 1 to 3, the blood collecting device 10 includes a display panel 12 on the front surface of the housing 11, and the housing 11
A vacuum blood collection chamber 13 is formed inside the chamber. Reference numeral 14 is an opening / closing lid of the blood collection chamber 13, 15 is a hinge of the lid 14, 16 is the blood collection chamber 1.
3 is a sealing rubber for hermetically sealing 3. 14A is a handle of the lid 14. Further, the blood collection device 10 has a vacuum pump 17 and a control device 18 built-in at the bottom of the housing 11.

The vacuum blood collection chamber 13 of the blood collection device 10 is connected to the intake port 17A of the vacuum pump 17 to enable decompression, and includes a bag tray 19 for supporting the blood bag (blood solution) 1 made of polyvinyl chloride or the like. There is. The mounting device 10 is
While the vacuum blood collection chamber 13 is depressurized, a predetermined negative pressure is applied to the blood bag 1 supported by the bag tray 19 to collect blood. At this time, the blood collecting device 10 shakes the bag tray 19 to stir the anticoagulant such as heparin loaded in the blood bag 1 in advance and the blood, and measures the weight of the blood bag 1 to collect the blood. Measure the quantity.

The structure of rocking the bag tray 19 in the blood collecting device 10 and the structure of measuring the weight of the blood bag 1 are as follows.

First, a pedestal 20 is installed at the bottom of the vacuum blood collection chamber 13,
A swing frame 22 that is rotatable is supported on the frame 20 via a support shaft 21. A swing motor 23 is fixed to the gantry 20, and a driving shaft 24 driven by the swing motor 23 is supported. A crank wheel 28 is fixed to one end of the drive shaft 24.
One end of the link 29 is connected on the radius of rotation of, and the other end of the link 29 is connected to the swing frame 22.

On the other hand, a scale mounting member 31 is fixed to the upper surface of the swing frame 22, and a scale (weight measuring means) 33 is cantilevered on the scale mounting member 31. The scale 33 is composed of a substantially rectangular (parallelogram) frame as shown in FIG. The scale 33 is provided with strain gauges 34 as weight sensors that are attached to the two positions on the upper surface and the two positions on the lower surface, respectively, and form a Wheatstone bridge circuit.
5, the bag tray 19 is fixed via the receiving plate 36. The scale 33 has a weight sensor amplification unit 38.

That is, the blood collecting apparatus 10 rotates the driving shaft 24 and the crank wheel 28 by the operation of the rocking motor 23, thereby rocking the rocking frame 22, and the scale 33 on the rocking frame 22.
The bag tray 19 supported via the table is rocked. At this time, as shown in FIGS. 2 and 6, the bag tray 19 has a maximum rising point of + α degrees with respect to the horizontal and −β.
Two points above and below the lowest descent point can be rocked as turning points in the rocking process. Further, one cycle time of the rocking that the rocking motor 23 imparts to the bag tray 19 is the power supply frequency.
It is about 1.0 to 2.6 seconds in the 60Hz area and about 1.2 to 3 seconds in the power supply frequency 50Hz area. If the one cycle time is too long, the mixing of the anticoagulant in the blood bag 1 with the blood becomes weak, but if it is too short, the blood in the blood bag 1 will not move against the movement of the bag tray 19. It exhibits a phenomenon that the tracking is poor and it becomes difficult to mix. The blood collecting device 10 also supports the bag tray 19 on a scale 33 that is cantilevered on the swing frame 22 via a scale attachment member 31.
The weight of the blood bag 1 is measured by the change in the output of the strain gauge 34 based on the flexural deformation of the blood, and thus the blood collection amount is measured.

The blood sampling device 10 detects the rotational position of the detection cam 39 provided at the other end of the driving shaft 24 by the optical sensor 40,
The control device 18 recognizes the current swing angle position of the bag tray 19 by the swing motor 23, and the bag tray 19 is at the turning point of either the highest point or the lowest point. The weight of the blood bag 1 is measured by taking in the measurement result of the scale 33 described above.

At this time, in the control device 18 of the blood collection device 10, the bag tray 19 is at the turning point at the initial or intermediate stage of blood collection into the blood bag 1, and when the measurement result of the scale 33 is taken in, the swing motor is used. The swing motion of the bag tray 19 by 23 is not completely stopped, or is temporarily stopped for about 0.2 seconds.
In addition, when the bag tray 19 is at the folding point and the measurement result of the scale 33 is to be taken in at the end stage of blood collection when the remaining amount of blood collected in the blood bag 1 is, for example, 50 ml or less, the swing motor 23
The swinging motion of the bag tray 19 due to is temporarily stopped for about 0.5 seconds so that the weight of the blood bag 1 can be accurately measured at the end stage of blood collection.

Further, in the blood collecting device 10, the blood bag 1 is reliably rocked so as to prevent blood coagulation, and the rocking space of the bag tray 19 is made as small as possible to make the blood collecting device 10 compact. In order to realize this, the appropriate swing angle range of the highest rising point or the lowest falling point of the bag tray 19 "[+ α
[Degrees] to [-[beta] degrees] "is defined as follows: That is, [+ [alpha] degrees] that determines the above-mentioned maximum rise point of the bag tray 19 is
[+10 degrees to +40 degrees], more preferably [+10 degrees to +30 degrees]
[Degrees], most preferably within an angle range of [+15 degrees to +25 degrees], and in this example, [+20 degrees]. In addition, the [-β degree] that determines the above-mentioned lowest descent point of the bag tray 19 is [-10 degrees to -40 degrees], more preferably [-
10 degrees to -30 degrees], and most preferably within the angle range of [-15 degrees to -25 degrees].
Degree].

In addition, the swing angle range of the above-mentioned bag tray 19 "[+ α
Degree] to [-β degree] "is experimentally changed to" [+8 degrees] to [-
8 degrees] ”,“ [+12 degrees] ~ [-12 degrees] ”,“ [+15 degrees]
~ [-15 degrees] "," [+18 degrees] ~ [-18 degrees] "," [+
21 degrees]-[-21 degrees] "," [+24 degrees]-[-24 degrees] ",
[+30 degrees]-[-10 degrees] "," [+25 degrees]-[-15
]], "[+25 degrees] ~ [-5 degrees]", "[+20 degrees] ~
Blood bag 1
As a result of comparing the degree of mixing of anticoagulant and blood with
[+20 degrees] to [-20 degrees] "was found to be optimal.

As shown in FIG. 5, the blood collection device 10 connects the intake port 17A of the vacuum pump 17 and the vacuum blood collection chamber 13 with a vacuum pipe 41, and is closed in the middle of the vacuum pipe 41 by turning on an exhaust solenoid 42. An exhaust valve 43 that opens by gravity when the exhaust solenoid 42 is turned off is provided. Blood collection device 10
Creates a constant negative pressure (vacuum level) in the vacuum blood collection chamber 13 by controlling the on / off of the vacuum pump 17, and opens the exhaust valve 43 at the end of blood collection to open the vacuum blood collection chamber 13 to the atmosphere.

The blood collection device 10 includes a tube holder 4 at a portion adjacent to the vacuum blood collection chamber 13 at an upper portion on the front side of the housing 11.
4, the blood collection tube 2 connected to the hematology bag 1 housed in the vacuum blood collection chamber 13 can be drawn out. The tube holder 44 includes a tube clamp (blood collection stopping means) 46 driven by a tube clamp solenoid 45. The tube clamp 46 closes the blood collection tube 2 by clamping and stops the blood collection operation of the blood bag 1. Reference numeral 47 is a clamp release button for the tube clamp 46, and 48 is a clamp button for operating the tube clamp 46 in an emergency.

The display panel 12 of the blood collection device 10 includes a blood collection amount / vacuum degree switching display lamp 49, blood collection amount / vacuum degree switching switches 50, 40.
0ml / 200ml switching indicator lamp 51, 400ml / 200ml
Changeover switch 52, stop switch 53, start switch 5
4, a use bag display lamp 55, a use bag changeover switch 56, and a blood collection amount / vacuum degree display portion 57. The blood collection device 10 includes a power switch 58 and a fuse holder 59 at the lower front portion of the housing 11, and a power connector 60 at the lower rear portion of the housing 11.

Next, the control device 18 of the blood collection device 10 will be described.
As shown in FIG. 7, the control device 18 mainly includes a main control circuit 61, a drive circuit 62, and a display circuit 63. In addition, 64 is a power supply unit.

The main control circuit 61 is a CPU (central processing unit) [device 10
Including a memory in which a control program for a series of operations is written] 65, a memory (storage means) 66, an input / output control unit 67, an LED (light emitting diode) drive circuit 6
8, a buzzer 69, and a fail safe circuit 70. It should be noted that the detection signals of the above-mentioned optical sensor 40 for detecting the swing position of the bag tray 19 and the blood leak sensor 71 for detecting blood leak from the blood bag 1 are transferred to the input / output control unit 67. Has become.

The memory 66 is composed of a non-volatile memory such as EA-BOM and EEP-ROM. The stored data can be rewritten and read, and the stored data can be held without applying a power supply voltage. The stored data of the memory 66 includes the negative pressure generated in the vacuum blood collection chamber 13, the set blood collection amount in the blood bag 1, the swing extension time of the bag tray 19 after the blood collection is completed, and the like.

The buzzer 69 sounds differently depending on the completion of blood collection, the error of the negative pressure formed in the vacuum blood collection chamber 13, the rotation error of the rocking motor 23, the blood leak detection of the blood leak sensor 71, and the like.

The fail-safe circuit 70 monitors the occurrence of runaway of the CPU 65 and stops the device on the safe side when the runaway occurs.

The drive circuit 62 is connected to the main control circuit 61, and
A / D conversion circuit 72 is provided. A weight sensor amplification unit 38 in which the strain gauge 34 is connected to the A / D conversion circuit 72.
And a pressure sensor 73, which is provided in the above-mentioned vacuum pipe 41 and detects the negative pressure of the vacuum blood collection chamber 13, is connected via a pressure sensor amplifier circuit 74.

At this time, the CPU 65 of the control device 18 calculates the blood sampling weight by assuming that the output y of the strain gauge 34 constitutes a linear function of y = aw + b with respect to the measured blood sampling weight w. Also, C
The PU 65 calculates the pressure by assuming that the output z of the pressure sensor 73 constitutes a linear function of z = cp + d with respect to the measured pressure p.

The drive circuit 62 includes a solenoid drive circuit 75 that controls the tube clamp solenoid 45, a solenoid drive circuit 76 that controls the exhaust solenoid 42,
A pump drive circuit 78 for turning on / off the power supply switch 77 of the vacuum pump 17 and a motor drive circuit 80 for turning on / off the power supply switch 79 of the swing motor 23 are provided.

The CPU 65 of the control device 18 controls the pressure sensor 7
3 and the set pressure of the vacuum blood collection chamber 13 which is the data stored in the memory 66 are obtained, and the power supply switch 77 of the vacuum pump 17 is turned on as described above so that the detected pressure matches the set pressure. Turn on / off. This allows
The negative pressure of the vacuum blood collection chamber 13 slightly changes within a certain range of the set pressure, and as a result, a constant pressure state is obtained.

Next, a blood collection operation procedure by the blood collection device 10 will be described.

The power switch 58 is turned on.

Select the blood sampling amount with the 400ml / 200ml selector switch 52. The selection result is displayed on the switching display lamp 51.

A bag to be used is selected by using the bag changeover switch 56. The selection result is displayed on the display lamp 55. The types of action bags include a single (S) for the parent bag only, a double (D) that also includes one or more small bags,
There are Triple (T) and Quadruple (Q).

The blood collecting needle provided at the end of the blood collecting tube 2 is punctured in the donor to collect blood to some extent.

Put the blood bag 1 into the vacuum blood collection chamber 13 and fill the bag pan 1
9 and the blood collection tube 2 is set in the tube holder 44.

The start switch 54 is turned on. The control device 18 drives and controls the vacuum pump 17 and the swing motor 23, and the vacuum blood collection chamber 1
Blood collection by decompression of 3 and shaking of the bag tray 19 are performed. Further, the control device 18 obtains the output of the weight sensor amplifying unit 38 at the timing as described above when the bag tray 19 is at the turning point of either the highest point or the lowest point in the swinging process, and the blood bag is obtained. The detected blood collection amount of 1 is detected, and the set blood collection amount written in the memory 66,
Using the specific gravity of blood and the preregistered weight of blood bag 1,
The remaining blood sampling volume (volume) is calculated by the following equation (1).

Residual blood collection amount (ml) = [set blood collection amount (g) + pre-registered weight (g) -measured blood collection amount (g)] / specific gravity (g / ml) (1) The control device 18 is the above calculation result. On condition that the residual blood collection amount has reached zero, the blood collection tube 2 is closed by the tube clamp 46 and the blood collection operation for the blood bag 1 is stopped. At this time, the controller 18 stops the vacuum pump 17 and opens the exhaust valve 43 to open the vacuum blood collection chamber 13 to the atmosphere.

After the blood collection is completed, the control device 18 extends and drives the swing motor 23 for a certain period of time to swing the bag tray 19. After that, the buzzer notifies the end of blood collection.

The clamp release button 47 is turned on, the blood collection tube 2 is removed from the tube holder 44, and the blood bag 1 is taken out from the vacuum blood collection chamber 13.

In the blood collection device 10, the upper opening 11A of the housing 11 for loading and unloading the blood bag 1 into and from the bag tray 19 is set so as to have a downward slope from the rear side of the housing 11 toward the front side. ing.

Next, the operation of the above embodiment will be described.

According to the above-described embodiment, blood can be collected while rocking the blood bag 1 by the rocking motor 23, and when the blood bag 1 is at the turning point of the rocking process, the blood collection weight is measured. Therefore, there are the following actions (1) and (2).

(1) The blood collecting weight is measured when the bag saucer 19 has the least swinging motion (the turning point above or below the swinging process or in the vicinity thereof), and the shaking occurring in the blood in the blood bag 1 is measured. Accurate weight measurement is possible because the measurement is performed at the minimum timing.

(2) Since the bag tray 19 is not temporarily stopped in the intermediate process of rocking, the anticoagulant in the blood bag 1 and blood can be mixed well in the rocking process and blood coagulation can be prevented.

Further, according to the above-described embodiment, at least at the end stage of blood collection, the bag tray 19 is at the turning point of the swing, and when the measurement result of the scale 33 is taken in, the swing operation by the swing motor 23 is temporarily stopped. It will be. Therefore, there is the effect of (3) below.

(3) The weight of the collected blood is measured under the condition where the bag saucer 19 is gently stopped, and the shake occurring in the blood in the blood bag 1 is measured in a calmed state. You can

[Effects of the Invention] As described above, according to the present invention, when blood is collected while rocking the blood container in order to prevent blood from coagulating, the accuracy of measuring the amount of blood collected can be stably improved.

[Brief description of drawings]

FIG. 1 is a front view showing a blood collecting device according to one embodiment of the present invention, FIG. 2 is a side view showing a main portion of FIG.
1 is a plan view of FIG. 1, FIG. 4 is a side view showing a scale, FIG. 5 is a vacuum circuit diagram, FIG. 6 is a rocking state diagram, and FIG. 7 is a control block diagram. 1 ... Blood bag (blood container), 10 ... Blood collection device, 19 ... Bag saucer (container support part), 22 ... Swing frame (swing platform), 23 ... Swing motor, 33 ... Scale (Weight measuring means), 65 ... CPU (control means).

Claims (2)

[Claims] 1. A container support part for supporting a blood container, an oscillating means for oscillating the container support part during blood collection to the blood container, and a weight measurement for measuring the weight of blood collected in the blood container during blood collection. In the blood collecting apparatus having the means, in the state where the container support portion is at the turning point of the swinging process by the swinging means,
A blood sampling device for measuring a blood sampling weight, comprising control means for taking a measurement result of the weight measuring means and determining a blood sampling weight or a blood sampling residual amount in a blood container based on the measurement result. 2. The blood vessel container is at the turning point of the swinging process by the swinging means at least at the end stage of collecting blood, and when the measurement result of the weight measuring means is taken in,
The blood sampling apparatus according to claim 1, wherein the swinging operation of the container support portion by the swinging means is temporarily stopped.