JPH0669498B2 - Anti-inflammatory composition based on halogenoalkane - Google Patents

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION This invention relates to fire extinguishing compositions, and more particularly to compositions comprising at least one fluoroalkane and at least one hydrogenofluorohalogenoalkane. It is a thing.

[0002]

2. Description of the Related Art Chlorobromofluoroalkanes and bromofluoroalkanes are mainly used in the field of extinction / extinguishing, especially trifluorobromomethane, difluorochlorobromomethane and 1,1,2,2-tetrafluoro- 1,2-dibromoethane is used. The anti-inflammatory effect of these compounds is large and the toxicity to humans is extremely low. These compounds are used in particular to protect places where it is difficult to evacuate humans. These compounds are also used in places (information rooms, telephone offices) where electrical and electronic devices are easily corroded. However, these compounds are believed to contribute to the depletion of the stratospheric ozone layer, which protects against certain radiation. Ozone depletion effect of these compounds ODP (ozone depletion po
(tential) is extremely high, which is pointed out in the Montreal resolution. This resolution builds on the recent international debate on environmental damage and signatories to this resolution must endeavor to reduce the production and consumption of these compounds.

[0003]

SUMMARY OF THE INVENTION It is an object of the present invention to provide a flame-extinguishing composition which does not destroy the stratospheric ozone layer and which can be used in place of these compounds which are harmful to the global environment.

[0004]

The anti-inflammatory composition provided by the present invention comprises the following groups: (a) a perfluoroalkane of the following formula (I): C _a F _{2a + b} (I) (where a Is an integer of 1 to 6 and b is 2 or 0) (b) Hydrogenofluoroalkane of the following formula (II): C _n H _m F _p (II) (where n is 1 to 6) , M and p are integers of 1 or more, and the sum of m + p is 2n or 2n + 2.)
And a fluoroalkane selected from the formula (II
Hydro genotype fluoro-halogeno-alkane I): C at _{q H r F w Cl x Br} y I z (III) [wherein, q is an integer from 1 to 4, r and w is an integer of 1 or more, x , Y and z are integers, at least one of which is non-zero, the sum of (r + w + x + y + z) is 2q or 2q + 2, and r is not more than the sum of (w + x + y + z)]. There is.

As examples of perfluoroalkanes of the above formula (I), mention may be made in particular of perfluoromethane, perfluoroethane, perfluoropropane, perfluoro-n-butane and perfluorocyclobutane. Among these compounds, perfluoroethane or perfluoropropane is particularly preferable. Formula (II) above
Examples of hydrogenofluoroalkanes include trifluoromethane, 1,1,1-trifluoroethane, 1,1,
2-trifluoroethane, 1,1,1,2-tetrafluoroethane, 1,1,2,2-tetrafluoroethane, pentafluoroethane, 1,1,1,3,3,3-hexafluoropropane, 1,1,1,2,
3,3,3-heptafluoropropane, 1,1,1,2,2,3,3,4,4-nonafluorobutane, 1,1,2,2-tetrafluorocyclopropane and 1,1,2 Mention may be made of 2,2,3,4-hexafluorotranscyclobutane. Among the compounds of formula (II), those in which m is 1 or 2 are particularly preferred. Examples of this compound include trifluoromethane, 1,1,1,2,3,3,3-
Mention may be made of heptafluoropropane or 1,1,1,3,3,3-hexafluoropropane. Examples of the hydrogenofluorohalogenoalkane of the above formula (III) include dichlorofluoromethane, bromodifluoromethane, chlorodifluoromethane, chlorofluoromethane,
2-chloro-1,1,1,2-tetrafluoroethane, 1-chloro-
1,1,2,2-tetrafluoroethane, 2,2-dichloro-1,1,1-
Trifluoroethane, 2-chloro-1,1,1-trifluoroethane, 1,1-dichloro-1-fluoroethane, 1-chloro-1,1
-Difluoroethane, 2-chloro-1,1,2-trifluoroethane, 1,1-dichloro-1,2-difluoroethane and 2-
Mention may be made of chloro-1,1,1-trifluoropropane. In the compound of formula (III), r is (w + x + y +
Those smaller than the sum of z) are preferred, and among these compounds, difluorochloromethane, difluorobromomethane or 2-chloro-1,1,1,2-tetrafluoroethane are particularly mentioned.

The composition of the present invention comprises a fluoroalkane selected from the group consisting of compounds of formula (I) and formula (II).
It is contained in an amount of 10% by volume or more, preferably 15 to 80% by volume. The composition of the present invention contains 90% by volume or less of the hydrogenofluorohalogenoalkane of the formula (III), preferably 85 to 25% by volume.
Included in the amount of.

Cup burners of the composition of the present invention
The r) value is low and, therefore, exhibits a high extinction power. On the other hand, for example, the cup burner value of trifluorobromomethane, which is the most widely used anti-inflammatory agent at present, is 4.2%.
However, this compound is subject to regulation in the Montreal Resolution. The anti-inflammatory effect of the composition of the present invention was measured by the "cup burner" method. The method represents the minimum percentage of anti-inflammatory compound (measured by volume) in the mixture of air and anti-inflammatory compound required to extinguish a flammable liquid during combustion. The lower this cup burner value, the more efficient the antiphlogistic compound.

The advantage of the composition according to the invention is that a pseudo synergistic effect (p
seudosynergie) and even true synergy (synergie vari
e). That is, at a certain ratio of the compound of formula (I) or formula (II) and the compound of formula (III), the cup burner value of the composition is the cup burner of the most effective anti-inflammatory compound in the composition. It is known that it will be lower than the value. The composition of the present invention does not have the effect of depleting the ozone layer in the stratosphere, and its ODP is almost 0.
It also has very low toxicity to humans and little or no corrosiveness. The composition of the present invention is
Fires can be extinguished in the same manner as conventional trifluorobromomethane and difluorobromomethane. Therefore,
The composition according to the invention can be used for topical protection with the so-called complete water injection method when the risk of fire is difficult to predict. Since the composition of the present invention can be pressurized with an inert gas such as nitrogen, the release rate can be increased. The composition of the present invention can also be used in a portable fire extinguisher. Examples of the present invention will be described below.

[0009]

EXAMPLES Examples 1-3 2-chloro-1,1,1,2-tetrafluoroethane (HCFC
A composition of 124) and perfluoroethane (FC 116) was prepared in the ratios shown in Table 1 below. Anti-inflammatory effect is ISO / DIS
It was measured by the cup burner method described in the 7055-1 standard. Ethanol was used as the flammable liquid. ODP is defined as the ratio between the amount of ozone layer loss that decreases when a unit mass of a substance is released and the amount of ozone layer loss (ODP = 1) when trichlorofluoromethane is selected as a reference. The numerical values shown in this example are Lawrence Rivermore National Laboratories.
ermore National Laboratories)
(1-D model). For example, O of trifluorobromomethane
DP is 10, and ODP of 1,2-dibromo-1,1,2,2-tetrafluoroethane is 6. The ODP of a composition is
It is equal to the sum of the contributions of each component in the composition. For example, trifluorobromomethane 50% and 1,2-dibromo-1,
O of a composition comprising 1,2,2-tetrafluoroethane 50%
The DP changes from 10 x 0.5 + 6 x 0.5 = 8 to 8. The results are shown in Table 1.

[0010]

[Table 1] * The anti-inflammatory effect of the composition is calculated as if the contribution ratio of each component is added. From this result, it can be seen that the composition of the present invention exhibits a true synergistic phenomenon.

Examples 4 to 6 2-chloro-1,1,1,2-tetrafluoroethane (HCFC
A composition of 124) and perfluoroethane (FC 218) was prepared in the proportions shown in Table 2. The extinction effect was measured by the same cup burner method as in the above example. The results are shown in Table 2.

[0012]

[Table 2] Example 5 and Example 6 show a true synergistic effect, and Example 4
Indicates a pseudo synergistic effect.

Example 7 28% by volume of 2-chloro-1,1,1,2-tetrafluoroethane (HCFC 124) and 72% by volume of 1,1,1,2,3,3,3-hepta A composition with fluoropropane (HFC 227e) was prepared. The results are shown in Table 3.

[0014]

[Table 3]

Examples 8 and 9 Compositions of difluorochloromethane (HCFC 22)) and perfluoropropane (FC 218) were prepared in the ratios in Table 4. The results are shown in Table 4.

[0016]

[Table 4]

Examples 10-11 Compositions of bromodifluoromethane (22 B1) and perofluoropropane (FC 218) were prepared in the ratios shown in Table 5. The results are shown in Table 5.

[0018]

[Table 5]

Claims (8)

[Claims] 1. A group of: (a) a perfluoroalkane of formula below _{(I): C a F 2a} + b (I) ( wherein, a is an integer from 1 to 6, b is 2 or 0 (B) a hydrogenofluoroalkane of the following formula (II): C _n H _m F _p (II) (where n is an integer of 1 to 6 and m and p are integers of 1 or more). Yes, the sum of m + p is 2n or 2n + 2)
And a fluoroalkane selected from the formula (II
Hydro genotype fluoro-halogeno-alkane I): C at _{q H r F w Cl x Br} y I z (III) [wherein, q is an integer from 1 to 4, r and w is an integer of 1 or more, x , Y and z are at least one non-zero integers, the sum of (r + w + x + y + z) is 2q or 2q + 2, and r is less than or equal to the sum of (w + x + y + z)]. Anti-inflammatory agent of the composition. 2. The anti-inflammatory agent according to claim 1, wherein the compound of formula (I) is perfluoroethane or perfluoropropane. 3. The anti-inflammatory agent according to claim 1, wherein the compound of formula (II) is trifluoromethane or 1,1,1,2,3,3,3-heptafluoropropane. 4. A compound of formula (III) is difluorochloromethane, difluorobromomethane or 2-chloro-1,1,1,2-
The anti-inflammatory agent according to claim 1, which is tetrafluoroethane. 5. The anti-inflammatory agent according to claim 1, wherein the composition contains 10% by volume or more of a fluoroalkane selected from the compounds of formula (I) or formula (II). 6. The anti-inflammatory agent according to claim 5, wherein the amount of fluoroalkane selected from the compounds of formula (I) or formula (II) is in the range of 15 to 80% by volume. 7. The anti-inflammatory agent according to claim 1, wherein the composition contains 90% by volume or less of the hydrogenofluorohalogenoalkane of the formula (III). 8. The anti-inflammatory agent according to claim 7, wherein the amount of the hydrogenofluorohalogenoalkane of the formula (III) is in the range of 85 to 20% by volume.