JPH07503465A - コレシストキニンアンタゴニストとして有用な３‐フェニルウレイド‐アゼピン‐２‐オン及び‐ベンゾアゼピン‐２‐オン - Google Patents

コレシストキニンアンタゴニストとして有用な３‐フェニルウレイド‐アゼピン‐２‐オン及び‐ベンゾアゼピン‐２‐オン

Info

Publication number: JPH07503465A
Authority: JP; Japan
Prior art keywords: phenyl; formula; ureido; butyl; oxo
Prior art date: 1992-01-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP5513196A

Other languages

English (en)

Japanese (ja)

Inventor

ロウ，ジョン・エイ・ザ・サード

Original Assignee

フアイザー・インコーポレイテツド

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-27

Filing date

1992-12-16

Publication date

1995-04-13

1992-12-16 Application filed by フアイザー・インコーポレイテツド filed Critical フアイザー・インコーポレイテツド

1995-04-13 Publication of JPH07503465A publication Critical patent/JPH07503465A/ja

Status Pending legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

JP5513196A 1992-01-27 1992-12-16 コレシストキニンアンタゴニストとして有用な３‐フェニルウレイド‐アゼピン‐２‐オン及び‐ベンゾアゼピン‐２‐オン Pending JPH07503465A (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US82567792A	1992-01-27	1992-01-27
US825,677		1992-01-27
PCT/US1992/010720 WO1993015059A1 (en)	1992-01-27	1992-12-16	3-phenylureido-azepin-2-ones and -benzazepin-2-ones useful as cholecystokinin antagonists

Publications (1)

Publication Number	Publication Date
JPH07503465A true JPH07503465A (ja)	1995-04-13

Family

ID=25244657

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP5513196A Pending JPH07503465A (ja)	1992-01-27	1992-12-16	コレシストキニンアンタゴニストとして有用な３‐フェニルウレイド‐アゼピン‐２‐オン及び‐ベンゾアゼピン‐２‐オン

Country Status (19)

Country	Link
EP (1)	EP0625145A1 (sr)
JP (1)	JPH07503465A (sr)
KR (1)	KR950700257A (sr)
CN (1)	CN1074903A (sr)
AU (1)	AU3276193A (sr)
BR (1)	BR9207071A (sr)
CA (1)	CA2117367A1 (sr)
CZ (1)	CZ391092A3 (sr)
FI (1)	FI943513A0 (sr)
HU (1)	HUT70496A (sr)
IL (1)	IL104472A0 (sr)
MX (1)	MX9300409A (sr)
NO (1)	NO942775L (sr)
NZ (1)	NZ245759A (sr)
RU (1)	RU94038063A (sr)
TW (1)	TW213901B (sr)
WO (1)	WO1993015059A1 (sr)
YU (1)	YU4393A (sr)
ZA (1)	ZA93582B (sr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2097688A1 (es) *	1993-07-14	1997-04-01	Pfizer	Hexahidroazepinonas y tetrahidrobenzazepinonas sustituidas.
JP2862675B2 (ja) *	1993-07-26	1999-03-03	フアイザー・インコーポレイテツド	選択的コレシストキニン−ｂ受容体拮抗薬としてのテトラヒドロ−１ｈ−ベンゾアゼピノンおよびヘキサヒドロアゼピノン
CA2176019A1 (en) *	1993-11-22	1995-06-01	John J. Baldwin	3-acylaminobenzazepines
US5453424A (en) *	1993-11-22	1995-09-26	Merck & Co., Inc.	Furanodiazepines
WO1996010564A1 (en) *	1994-10-04	1996-04-11	Pfizer Inc.	Processes and intermediates for preparing 3-amino-benzo(b)azepinones
ES2171196T3 (es) *	1994-10-14	2002-09-01	Glaxosmithkline Spa	Uso de antagonistas del receptor cck-b para el tratamiento de trastornos del sueño.
DE10153348A1 (de) *	2001-10-29	2003-05-08	Gruenenthal Gmbh	Substituierte Benzo(b)azepin-2-on-Verbindungen
WO2007120160A2 (en) *	2005-06-16	2007-10-25	Novartis Ag	Lactam containing hcv inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0166357A3 (en) *	1984-06-26	1988-10-26	Merck & Co. Inc.	Benzofused lactams and pharmaceutical compositions containing them
US4767756A (en) *	1987-07-17	1988-08-30	E. R. Squibb & Sons, Inc.	3-substituted benzazepines
EP0322779A3 (en) *	1987-12-29	1991-05-08	Yoshitomi Pharmaceutical Industries, Ltd.	Benzolactam compounds and pharmaceutical uses thereof
US5206234A (en) *	1990-10-22	1993-04-27	Merck & Co., Inc.	Benzolactam analogs as antagonists of cck

1992
- 1992-12-15 TW TW081110044A patent/TW213901B/zh active
- 1992-12-16 WO PCT/US1992/010720 patent/WO1993015059A1/en not_active Ceased
- 1992-12-16 JP JP5513196A patent/JPH07503465A/ja active Pending
- 1992-12-16 RU RU94038063/04A patent/RU94038063A/ru unknown
- 1992-12-16 FI FI943513A patent/FI943513A0/fi unknown
- 1992-12-16 EP EP93901470A patent/EP0625145A1/en not_active Withdrawn
- 1992-12-16 HU HU9402195A patent/HUT70496A/hu unknown
- 1992-12-16 CA CA002117367A patent/CA2117367A1/en not_active Abandoned
- 1992-12-16 BR BR9207071A patent/BR9207071A/pt not_active Application Discontinuation
- 1992-12-16 KR KR1019940702565A patent/KR950700257A/ko not_active Ceased
- 1992-12-16 AU AU32761/93A patent/AU3276193A/en not_active Abandoned
- 1992-12-28 CZ CS923910A patent/CZ391092A3/cs unknown
1993
- 1993-01-21 CN CN93101158A patent/CN1074903A/zh active Pending
- 1993-01-21 IL IL104472A patent/IL104472A0/xx unknown
- 1993-01-26 MX MX9300409A patent/MX9300409A/es unknown
- 1993-01-26 YU YU4393A patent/YU4393A/sr unknown
- 1993-01-26 NZ NZ245759A patent/NZ245759A/en unknown
- 1993-01-27 ZA ZA93582A patent/ZA93582B/xx unknown
1994
- 1994-07-26 NO NO942775A patent/NO942775L/no unknown

Also Published As

Publication number	Publication date
CN1074903A (zh)	1993-08-04
NZ245759A (en)	1997-06-24
WO1993015059A1 (en)	1993-08-05
CZ391092A3 (en)	1994-01-19
EP0625145A1 (en)	1994-11-23
TW213901B (sr)	1993-10-01
CA2117367A1 (en)	1993-08-05
YU4393A (sr)	1996-01-09
NO942775D0 (no)	1994-07-26
KR950700257A (ko)	1995-01-16
IL104472A0 (en)	1993-05-13
RU94038063A (ru)	1996-05-27
FI943513A7 (fi)	1994-07-26
AU3276193A (en)	1993-09-01
FI943513L (fi)	1994-07-26
HUT70496A (en)	1995-10-30
FI943513A0 (fi)	1994-07-26
ZA93582B (en)	1994-07-27
HU9402195D0 (en)	1994-09-28
BR9207071A (pt)	1995-12-05
NO942775L (no)	1994-09-20
MX9300409A (es)	1993-07-01

Similar Documents

Publication	Publication Date	Title
DE69736812T2 (de)	2007-08-09	Neue integrin rezeptor antagonisten
JP6302912B2 (ja)	2018-03-28	２−オキソ−２，３，４，５−テトラヒドロ−１ｈ−ベンゾ［ｂ］ジアゼピン及びがんの治療におけるその使用
DE60132309T2 (de)	2009-01-02	Amin-derivate zur behandlung von apoptosis
CN105764905B (zh)	2019-06-07	新的八氢-环丁二烯并[1，2-c；3，4-c’]二吡咯-2基
TWI291466B (en)	2007-12-21	Piperidine derivatives, process for their preparation, pharmaceutical composition containing them and their medical use
UA122433C2 (uk)	2020-11-10	Заміщена піперидинова сполука та її застосування
CA3045816A1 (en)	2018-08-09	Oga inhibitor compounds
TW201105667A (en)	2011-02-16	Dihydronaphthyridinyl and related compounds for use in treating ophthalmological disorders
CN102056904A (zh)	2011-05-11	作为ampa受体调节剂的茚满衍生物
ES2303960T3 (es)	2008-09-01	Derivados de 2-(1h-indolilsulfanil)-bencilamina como isrs.
TWI857918B (zh)	2024-10-01	αvβ6整合素之抑制劑
CN107257801A (zh)	2017-10-17	选择性bace1抑制剂
UA123737C2 (uk)	2021-05-26	Похідне фенілпропанаміду та спосіб отримання, та його фармацевтичне застосування
AU2003241903A1 (en)	2003-12-19	Piperidine derivative, process for producing the same, and use
JPH10504569A (ja)	1998-05-06	向代謝性グルタメート受容体拮抗剤としてのピロリジニルジカルボン酸誘導体
DE69612292T2 (de)	2001-11-22	Furo-, thieno- und pyrrolopyridine und verwandte pyrinidin-, pyridazin- und triazinverbindungen verwendbar zur kontrolle von chemische synaptische übertragung
CN105324385A (zh)	2016-02-10	Bace抑制剂
JPH07502023A (ja)	1995-03-02	血小板糖蛋白質２ｂ／３ａの阻害剤として有用な環状化合物
CN101305003B (zh)	2011-06-08	用于治疗精神病和神经变性疾病的作为nAChR胆碱能配体的(1-氮杂-双环[3.3.1]壬-4-基)-[5-(1H-吲哚-5-基)-杂芳基)-胺
CN105712985A (zh)	2016-06-29	β-内酰胺后叶加压素V1a拮抗剂
CN100418525C (zh)	2008-09-17	对钙通道α-2-δ亚基具有亲合力的脯氨酸衍生物
JPH07503465A (ja)	1995-04-13	コレシストキニンアンタゴニストとして有用な３‐フェニルウレイド‐アゼピン‐２‐オン及び‐ベンゾアゼピン‐２‐オン
JP2024545515A (ja)	2024-12-09	複素環化合物
CN103282349A (zh)	2013-09-04	吲哚衍生物及其制备方法
CN108884093A (zh)	2018-11-23	6,7,8,9-四氢-5H-吡啶并[2,3-d]氮杂*多巴胺D3配体