JPH07541B2 - Toothpaste - Google Patents

Description

FIELD OF THE INVENTION The present invention relates to dentifrice and in particular a buffer system is used to maintain alkaline pH for a pre-determined period of brushing time, after which a color change is caused by a decrease in pH. Concerning the resulting toothpaste.

[Problems to be Solved by Prior Art and Invention]

Toothpastes that cause color changes during use have been previously described, but there has always been a problem in controlling and varying the length of time such changes occur. According to the present invention, the length of time over which the pH of the toothpaste is lowered is easily varied to produce the desired color change and this may be accomplished by adjusting the concentration of the buffer system.

[Means for solving problems]

According to the invention, (a) the composition comprises a buffer system which maintains an alkaline pH for a predetermined period of the brushing time, and (b) the color indicator exhibits a color at alkaline pH and the brushing time. After a predetermined period of time has passed, the abrasive material, which is a material exhibiting a different color caused by a decrease in pH due to saliva of the user, a base material acceptable for dental use, and saliva in advance There is provided a dentifrice composition comprising a color indicator which causes the toothpaste in the user's mouth to change color after a defined period of time.

A preferred buffer system for the compositions of the present invention has a brushing time of 30.
It consists of a combination of sodium phosphate (dibasic) and sodium hydroxide in a ratio sufficient to maintain an alkaline pH for -60 seconds.

Preferably two color indicators are used in combination when the user initiates brushing and the first color indicator imparts one color to the toothpaste and when the pre-determined period of time for brushing is complete. In addition, the second color indicator gives the user a different brush color instead of the first color to indicate that the user has brushed well. The second color indicator is activated by the drop in pH caused by the saliva of the user.

A preferred pH-sensitive color indicator is phenolphthalein, which exhibits a color at the beginning of the brushing period and will change color after a pre-determined period of brushing time. The change in color depends on the initial pH of the toothpaste, the alkaline pH.
Occurs when the pH drops from saliva to saliva. In that respect it shows a different color to inform the user that he has brushed for a sufficient amount of time.

When the pre-determined period of brushing time is complete, the second color indicator gives the user a different brush color instead of the first color to indicate that the user has brushed well . The second color indicator is activated by the drop in pH caused by the saliva of the user.

A preferred pH-sensitive color indicator is phenolphthalein, which exhibits a color at the beginning of the brushing period and will change color after a pre-determined period of brushing time. The change in color depends on the initial pH of the toothpaste, the alkaline pH.
Occurs when the pH drops from saliva to saliva. In that respect it shows a different color to inform the user that he has brushed for a sufficient amount of time.

Combinations of pH sensitive dyes such as phenolphthalein and FD and C Blu
e) No. 1 and Day & Sea Yellow No. 10 are used, and the combination of dyes will respond to the decrease in alkaline pH due to saliva. First the color of the phenolphthalein will be shown during brushing. After a pre-determined period of brushing, saliva in the user's mouth produces a second color as the pH decreases, thereby replacing the color of the phenolphthalein.

The dentifrice according to the invention is preferably 10% to 50% wetting agent, 10% to 40% deionized water, 20% to 40% abrasive such as calcium carbonate, dicalcium phosphate or silica, 0.
5% ~ 2.0% binder, 0.1% ~ 0.3% sweetener, 0.5% ~
5.0% fragrance, 0.005% ~ 0.025% colorant, 0.5% ~ 2.0
% Surfactant, 0.20% to 0.60% sodium hydroxide (having an ionic concentration and having a pH value adapted to produce a final pH in the toothpaste within the range of 10.5-11.5)
And 0.70% to 4.3% buffer (all% are% by weight). The dentifrice composition of the present invention may also include an effective amount of an anticaries agent such as sodium monofluorophosphate, sodium fluoride or stannous fluoride, alone or in combination. The dentifrice composition may also include desensitizing and / or antimicrobial agents. When phenolphthalein is used as a color indicator, the color of the toothpaste is 30-60 of brushing.
It will change from crimson to white in seconds. When a second dye, such as Day & Sea Yellow No. 10 or F Day & Sea Yellow No. 1, is also incorporated, the pink color will disappear and a yellow or blue color may occur 30-60 seconds after brushing. .

The dentifrice composition of the present invention may be in the form of a dentifrice with stripes. The core would then be white and would have a pH of about 11. Colored stripes such as blue are either transparent or opaque and contain suitable pH sensitive dyes. Stripes will have a pH of about 7. In this aspect of the invention, toothpaste is initially shown as white in the user's mouth. When brushed, the toothpaste turns pink, for example, and about 30
After ~ 45 seconds, it turns white again, indicating to the user that he has brushed for a sufficient amount of time. A white core would also have a pH of about 11 and would be colored stripes, for example a red stripe with a pH of about 11 would be combined with a white core. Upon brushing, the dentifrice turns pink and after about 30-45 seconds turns white as saliva lowers the pH (for white cores and blue streaks). When a color indicator is incorporated into the striped gel toothpaste, this will conveniently be done using a double compartmented tube.

The color indicator may also be combined with a second colorant if it is desired to change the dentifrice to another color other than white at the completion of the pretextured brushing period.

The surfactant in the composition of the present invention is preferably a low foaming material such as alkali metal salts of aliphatic alcohol sulphates, alkane sulphates and / or amine oxides (and a particularly preferred surfactant is lauryl alcohol sulphate). Sodium salt of ate). The concentration of surfactant is preferably about 1.15%.

〔Example〕

 The following example illustrates the invention.

Example 1 A dentifrice according to the present invention was prepared by combining the following ingredients according to well known and conventional methods. Ingredient% (wt / wt) Glycerin 30.350 Sodium carboxymethylcellulose 1.350 over scan Veegum (Veegum) F 1.000 deionised water 24.890 Sodium monofluorophosphate phosphine Agent 0.760 preparative sodium Satu Karin 0.250 phenolphthalein solution 1.000 sodium solution 0.250 Calcium carbonate hydroxide 38.000 Fragrance 1.000 Sodium Lauryl Sulfate 1.500 Total 100.000 Example 2 Toothpaste according to the present invention was prepared by combining the following ingredients according to well known conventional methods. Ingredient% (wt / wt) Glycerin 30.350 Sodium carboxymethylcellulose 1.350 over scan Veegum F 1.000 deionised water 24.890 Sodium monofluorophosphate phosphine Agent 0.760 preparative sodium Satu Karin 0.250 Dean. and. Combining the following components by methods toothpaste that want with a by-Sea Yellow No.10 0.005 dyes phenolphthalein solution 1.000 sodium hydroxide solution 0.250 Total 100.000 EXAMPLE 3 This invention is made known conventional Ingredient% ( Weight / weight) Glycerin 25.830 Sodium carboxymethylcellulos 1.350 S veegum F 1.000 Deionized water 24.890 Sodium monofluorophosphate 0.760 Sodium satsukarin 0.250 Phenophthalphthalein solution 1.000 Sodium hydroxide solution 0.510 Calcium carbonate 38.000 Perfume 1.000 Sodium lauryl sulphate Ato 1.150 dibasic sodium phosphate (anhydrous) 4.260 Total 100.000 and prepared by adding the ingredients for stripes prepared by combining the following ingredients according to known conventional methods. Ingredient% (wt / wt) polyethylene glycol 400 3.000 sodium carboxymethylcellulose 0.900 over scan calcium carrageenan 0.250 deionised water 16.840 Sodium monofluorophosphate phosphine Agent 0.760 preparative Sorbitol 70% 62.000 Sodium benzoate 0.200 Sodium Satu Karin 0.200 silicate solution of sodium 0.200 Silica 13.500 Titanium Dioxide 1.000 Sodium Lauryl Sulfate 1.150 Total 100.000 The manufacture of toothpastes, including toothed teeth , is well known to those skilled in the art. U.S. Pat.Nos. 3,996,863, 3,980,767,
Nos. 4,328,205 and 4358437 describe dentifrices that can be used in the manufacture of toothpastes according to the present invention and methods of making the same.

 ─────────────────────────────────────────────────── ─── Continuation of front page (72) Inventor Bernard Mizek, Tara Drive, Pomona, 10970, New York, USA 12 (56) References JP-A-60-75409 (JP, A) JP-A-55-139318 (JP) , A)

Claims (9)

[Claims] 1. A composition comprising: (a) a buffer system which maintains an alkaline pH for a predetermined period of brushing time; and (b) a color indicator which exhibits a color at alkaline pH and which has a brushing time of Abrasive material characterized by being a material exhibiting a different color caused by a decrease in pH due to the saliva of the user after a predetermined period of time, a base material acceptable for dentistry, and a predetermined texture when contacted with saliva. A dentifrice composition comprising a color indicator which causes the toothpaste in the user's mouth to change color after a predetermined period of time has elapsed. 2. The composition according to claim 1, wherein the color indicator is phenolphthalein. 3. Two color indicators are incorporated into the composition, the first color indicator exhibits its color at an alkaline pH and the second color indicator has passed a pre-determined period of brushing time. The composition according to claim (1) or (2), which exhibits its color caused by a decrease in pH caused by saliva of the user later. 4. Two kinds of color indicators are phenolphthalein and D and C yellow 1.
A composition according to claim (3) which is number 0. 5. A combination of sodium phosphate (dibasic) and sodium hydroxide in an amount sufficient to maintain an alkaline pH for a brushing time of 30 to 60 seconds. ~ The composition according to any one of (4). 6. A composition according to any one of claims (1) to (5), which contains an anticaries agent selected from sodium monofluorophosphate, sodium fluoride and stannous fluoride. object. 7. The composition according to any one of claims (1) to (6), wherein the abrasive is calcium carbonate, dicalcium phosphate or silica. 8. A striped toothpaste having a central white core and pastel or colored stripes, either clear or opaque, wherein the core has a pH of about 11. A composition according to any one of claims (1) to (7), wherein said composition comprises a pH sensitive dye and has a pH of about 7. 9. A striped toothpaste having a white central core and pastel or colored stripes, either clear or opaque, wherein the core has a pH of about 11. Contains at least one color indicator and has a pH of about 11
The composition according to any one of claims (1) to (7), which comprises: