MD2722B2 - Фармацевтическая композиция, содержащая карбонат кальция или его смесь с гидроксикарбонатом магния или с витамином D, используемая для профилактики или лечения остеопороза - Google Patents
Фармацевтическая композиция, содержащая карбонат кальция или его смесь с гидроксикарбонатом магния или с витамином D, используемая для профилактики или лечения остеопороза Download PDFInfo
- Publication number
- MD2722B2 MD2722B2 MDA20020265A MD20020265A MD2722B2 MD 2722 B2 MD2722 B2 MD 2722B2 MD A20020265 A MDA20020265 A MD A20020265A MD 20020265 A MD20020265 A MD 20020265A MD 2722 B2 MD2722 B2 MD 2722B2
- Authority
- MD
- Moldova
- Prior art keywords
- vitamin
- pharmaceutical composition
- magnesium
- osteoporosis
- prophylaxis
- Prior art date
Links
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 title abstract 4
- 229930003316 Vitamin D Natural products 0.000 title abstract 3
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 235000019166 vitamin D Nutrition 0.000 title abstract 3
- 239000011710 vitamin D Substances 0.000 title abstract 3
- 150000003710 vitamin D derivatives Chemical class 0.000 title abstract 3
- 229940046008 vitamin d Drugs 0.000 title abstract 3
- 208000001132 Osteoporosis Diseases 0.000 title abstract 2
- 229910000019 calcium carbonate Inorganic materials 0.000 title abstract 2
- OUHCLAKJJGMPSW-UHFFFAOYSA-L magnesium;hydrogen carbonate;hydroxide Chemical compound O.[Mg+2].[O-]C([O-])=O OUHCLAKJJGMPSW-UHFFFAOYSA-L 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 2
- 229920002472 Starch Polymers 0.000 abstract 2
- 229910052791 calcium Inorganic materials 0.000 abstract 2
- 239000011575 calcium Substances 0.000 abstract 2
- 229910052749 magnesium Inorganic materials 0.000 abstract 2
- 239000011777 magnesium Substances 0.000 abstract 2
- 239000008107 starch Substances 0.000 abstract 2
- 235000019698 starch Nutrition 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000001177 diphosphate Substances 0.000 abstract 1
- XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 abstract 1
- 235000011180 diphosphates Nutrition 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 235000011962 puddings Nutrition 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Изобретение относится к медицине, а именно к фармацевтической композиции, которая может быть использована для профилактики и лечения остеопороза.Сущность изобретения заключается в том, что фармацевтическая композиция содержит карбонат кальция или его смесь с гидроксикарбонатом магния или витамина D, где на дозу кальция 150...1500 мг, предпочтительней 200...600 мг, витамина D может приходиться 100...1000 МЕ, предпочтительней 400...900 МЕ или 20...500 мг, предпочтительней 150...300 мг магния, где активные вещества, содержащие кальций и магний, тонко измельчены, так что, по меньшей мере, 80% частиц размером менее 75 µм и, кроме того, содержат обычные адъюванты и фармацевтически приемлемые производные крахмала, предпочтительней, дифосфаткрахмал в количестве 5...40 вес. %, предпочтительней 15...25 вес. %, вещества растительного происхождения, способные образовывать с водой ксерогели, предпочтительней каррагенан, в количестве 0,1...1,0 вес. %, предпочтительней, 0,2...0,6 вес. %.Указанная композиция представлена в форме быстрорастворимого порошка, который при добавлении жидкости образует, после короткого перемешивания, напоминающую пудинг гелеобразную суспензию, хорошо переносимую пациентами.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SK498-2000A SK284948B6 (sk) | 2000-04-06 | 2000-04-06 | Liečivý prípravok s obsahom vápnika alebo zmesi vápnika a vitamínu D, alebo zmesi vápnika a horčíka v novej liekovej forme |
| PCT/SK2001/000004 WO2001076610A1 (en) | 2000-04-06 | 2001-03-15 | Pharmaceutical composition with a content of calcium or mixture of calcium and vitamin d or mixture of calcium and magnesium in a new formulation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD20020265A MD20020265A (en) | 2003-05-31 |
| MD2722B2 true MD2722B2 (ru) | 2005-03-31 |
Family
ID=20435843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20020265A MD2722B2 (ru) | 2000-04-06 | 2001-03-15 | Фармацевтическая композиция, содержащая карбонат кальция или его смесь с гидроксикарбонатом магния или с витамином D, используемая для профилактики или лечения остеопороза |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1274447A1 (ru) |
| AU (1) | AU2001239668A1 (ru) |
| BG (1) | BG107227A (ru) |
| CZ (1) | CZ303069B6 (ru) |
| EE (1) | EE200200584A (ru) |
| MD (1) | MD2722B2 (ru) |
| PL (1) | PL357777A1 (ru) |
| RU (1) | RU2002130196A (ru) |
| SK (1) | SK284948B6 (ru) |
| WO (1) | WO2001076610A1 (ru) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7067150B2 (en) * | 2002-04-16 | 2006-06-27 | Scepter Holdings, Inc. | Delivery systems for functional ingredients |
| DK1758557T3 (da) | 2004-05-11 | 2011-10-24 | Egalet Ltd | Kvældbar doseringsform omfattende gellangummi |
| UA95093C2 (ru) | 2005-12-07 | 2011-07-11 | Нікомед Фарма Ас | Способ получения кальциесодержащего соединения |
| ES2625260T5 (es) | 2009-03-26 | 2020-07-29 | Pulmatrix Operating Co Inc | Formulaciones de polvo seco y métodos para el tratamiento de enfermedades pulmonares |
| DK2315580T3 (da) * | 2009-03-26 | 2012-04-10 | Pulmatrix Inc | Farmaceutiske formuleringer og fremgangsmåder til behandling af luftvejsinfektioner |
| WO2012030645A1 (en) | 2010-08-30 | 2012-03-08 | Pulmatrix, Inc. | Respirably dry powder comprising calcium lactate, sodium chloride and leucine |
| BR112013007304B1 (pt) | 2010-09-29 | 2021-12-14 | Pulmatrix, Inc. | Pós secos de cátion de metal monovalente para inalação |
| CN107596518B (zh) | 2012-02-29 | 2021-04-23 | 普马特里克斯营业公司 | 可吸入干粉剂 |
| AU2014248455B2 (en) | 2013-04-01 | 2018-12-06 | Pulmatrix Operating Company, Inc. | Tiotropium dry powders |
| JO3456B1 (ar) | 2015-05-13 | 2020-07-05 | H Lundbeck As | فيروتيوكسيتين بيروجلوتامات |
| RU2726438C2 (ru) * | 2018-11-14 | 2020-07-14 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СтГМУ Минздрава России) | Способ получения сухой высокобелковой молочной смеси для профилактики остеопении у детей и подростков с целиакией |
| CN109453126A (zh) * | 2018-12-07 | 2019-03-12 | 浙江核力欣健药业有限公司 | 一种碳酸钙d3咀嚼片的组合物及其制备方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5587399A (en) * | 1992-12-23 | 1996-12-24 | Abbott Laboratories | Method for preparing medical foods for the nutritional support of infants/toddlers with metabolic diseases |
| US5637313A (en) * | 1994-12-16 | 1997-06-10 | Watson Laboratories, Inc. | Chewable dosage forms |
| WO1999047122A1 (en) * | 1998-03-16 | 1999-09-23 | Smtm Group, Llc | Chewable calcium supplement and method for making it |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4650669A (en) * | 1985-07-30 | 1987-03-17 | Miles Laboratories, Inc. | Method to make effervescent calcium tablets and calcium tablets produced thereby |
| CA1297035C (en) * | 1987-12-29 | 1992-03-10 | Warner-Lambert Canada Inc. | Chewable, non-gritty calcium citrate tablet |
| US5296476A (en) * | 1989-09-08 | 1994-03-22 | Henderson Esther G | Skin care compositions |
-
2000
- 2000-04-06 SK SK498-2000A patent/SK284948B6/sk not_active IP Right Cessation
-
2001
- 2001-03-15 CZ CZ20023292A patent/CZ303069B6/cs not_active IP Right Cessation
- 2001-03-15 WO PCT/SK2001/000004 patent/WO2001076610A1/en not_active Ceased
- 2001-03-15 EE EEP200200584A patent/EE200200584A/xx unknown
- 2001-03-15 EP EP01914325A patent/EP1274447A1/en not_active Withdrawn
- 2001-03-15 AU AU2001239668A patent/AU2001239668A1/en not_active Abandoned
- 2001-03-15 PL PL01357777A patent/PL357777A1/xx not_active Application Discontinuation
- 2001-03-15 MD MDA20020265A patent/MD2722B2/ru unknown
- 2001-03-15 RU RU2002130196/15A patent/RU2002130196A/ru unknown
-
2002
- 2002-10-29 BG BG107227A patent/BG107227A/xx unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5587399A (en) * | 1992-12-23 | 1996-12-24 | Abbott Laboratories | Method for preparing medical foods for the nutritional support of infants/toddlers with metabolic diseases |
| US5637313A (en) * | 1994-12-16 | 1997-06-10 | Watson Laboratories, Inc. | Chewable dosage forms |
| WO1999047122A1 (en) * | 1998-03-16 | 1999-09-23 | Smtm Group, Llc | Chewable calcium supplement and method for making it |
Also Published As
| Publication number | Publication date |
|---|---|
| PL357777A1 (en) | 2004-07-26 |
| MD20020265A (en) | 2003-05-31 |
| SK284948B6 (sk) | 2006-03-02 |
| CZ303069B6 (cs) | 2012-03-21 |
| BG107227A (en) | 2003-05-30 |
| RU2002130196A (ru) | 2004-03-27 |
| EP1274447A1 (en) | 2003-01-15 |
| WO2001076610A1 (en) | 2001-10-18 |
| AU2001239668A1 (en) | 2001-10-23 |
| SK4982000A3 (en) | 2001-10-08 |
| EE200200584A (et) | 2004-04-15 |
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