MD2722B2 - Pharmaceutical composition containing calcium carbonate or mixture thereof with magnesium hydroxycarbonate or with vitamin D, used for prophylaxis or treatment of osteoporosis - Google Patents
Pharmaceutical composition containing calcium carbonate or mixture thereof with magnesium hydroxycarbonate or with vitamin D, used for prophylaxis or treatment of osteoporosis Download PDFInfo
- Publication number
- MD2722B2 MD2722B2 MDA20020265A MD20020265A MD2722B2 MD 2722 B2 MD2722 B2 MD 2722B2 MD A20020265 A MDA20020265 A MD A20020265A MD 20020265 A MD20020265 A MD 20020265A MD 2722 B2 MD2722 B2 MD 2722B2
- Authority
- MD
- Moldova
- Prior art keywords
- vitamin
- pharmaceutical composition
- magnesium
- osteoporosis
- prophylaxis
- Prior art date
Links
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 title abstract 4
- 229930003316 Vitamin D Natural products 0.000 title abstract 3
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 235000019166 vitamin D Nutrition 0.000 title abstract 3
- 239000011710 vitamin D Substances 0.000 title abstract 3
- 150000003710 vitamin D derivatives Chemical class 0.000 title abstract 3
- 229940046008 vitamin d Drugs 0.000 title abstract 3
- 208000001132 Osteoporosis Diseases 0.000 title abstract 2
- 229910000019 calcium carbonate Inorganic materials 0.000 title abstract 2
- OUHCLAKJJGMPSW-UHFFFAOYSA-L magnesium;hydrogen carbonate;hydroxide Chemical compound O.[Mg+2].[O-]C([O-])=O OUHCLAKJJGMPSW-UHFFFAOYSA-L 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 2
- 229920002472 Starch Polymers 0.000 abstract 2
- 229910052791 calcium Inorganic materials 0.000 abstract 2
- 239000011575 calcium Substances 0.000 abstract 2
- 229910052749 magnesium Inorganic materials 0.000 abstract 2
- 239000011777 magnesium Substances 0.000 abstract 2
- 239000008107 starch Substances 0.000 abstract 2
- 235000019698 starch Nutrition 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000001177 diphosphate Substances 0.000 abstract 1
- XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 abstract 1
- 235000011180 diphosphates Nutrition 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 235000011962 puddings Nutrition 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention refers to medicine, namely to a pharmaceutical composition that may be used for prophylaxis and treatment of osteoporosis.Summary of the invention consists in that the pharmaceutical composition contains calcium carbonate or mixture thereof with magnesium hydroxycarbonate or with vitamin D, where to a dose of calcium of 150…1500 mg, preferably of 200…600 mg, may be taken 100…1000 IU, preferably 400…900 IU of vitamin D, or 20…500 mg, preferably 150…300 mg of magnesium, wherein the active substances containing calcium and magnesium are finely grounded so that at least 80% of particles have dimensions under 75 µm and, moreover, contain conventional adjuvants and pharmaceutically acceptable derivatives of starch, preferably diphosphate starch in a quantity of 5…40 wt%, preferably of 15…25 wt%; substances of vegetal origin able to form xerogels with the water, preferably carragheenan, in a quantity of 0,1…1,0 wt%, preferably of 0,2…0,6 wt%.The aforesaid composition represents a quick-soluble powder, which at the addition of liquids, after a short mixing, form a pudding resembling gellylike suspension, well-tolerated by patients.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SK498-2000A SK284948B6 (en) | 2000-04-06 | 2000-04-06 | Pharmaceutical composition with a content of calcium or mixture of calcium and vitamin D or mixture of calcium and magnesium in a new formulation |
| PCT/SK2001/000004 WO2001076610A1 (en) | 2000-04-06 | 2001-03-15 | Pharmaceutical composition with a content of calcium or mixture of calcium and vitamin d or mixture of calcium and magnesium in a new formulation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD20020265A MD20020265A (en) | 2003-05-31 |
| MD2722B2 true MD2722B2 (en) | 2005-03-31 |
Family
ID=20435843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20020265A MD2722B2 (en) | 2000-04-06 | 2001-03-15 | Pharmaceutical composition containing calcium carbonate or mixture thereof with magnesium hydroxycarbonate or with vitamin D, used for prophylaxis or treatment of osteoporosis |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1274447A1 (en) |
| AU (1) | AU2001239668A1 (en) |
| BG (1) | BG107227A (en) |
| CZ (1) | CZ303069B6 (en) |
| EE (1) | EE200200584A (en) |
| MD (1) | MD2722B2 (en) |
| PL (1) | PL357777A1 (en) |
| RU (1) | RU2002130196A (en) |
| SK (1) | SK284948B6 (en) |
| WO (1) | WO2001076610A1 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7067150B2 (en) * | 2002-04-16 | 2006-06-27 | Scepter Holdings, Inc. | Delivery systems for functional ingredients |
| DK1758557T3 (en) | 2004-05-11 | 2011-10-24 | Egalet Ltd | Swellable dosage form comprising gellan gum |
| UA95093C2 (en) | 2005-12-07 | 2011-07-11 | Нікомед Фарма Ас | Method for the preparation of calcium-containing compound |
| ES2625260T5 (en) | 2009-03-26 | 2020-07-29 | Pulmatrix Operating Co Inc | Dry powder formulations and methods for the treatment of lung diseases |
| DK2315580T3 (en) * | 2009-03-26 | 2012-04-10 | Pulmatrix Inc | Pharmaceutical formulations and methods for treating respiratory tract infections |
| WO2012030645A1 (en) | 2010-08-30 | 2012-03-08 | Pulmatrix, Inc. | Respirably dry powder comprising calcium lactate, sodium chloride and leucine |
| BR112013007304B1 (en) | 2010-09-29 | 2021-12-14 | Pulmatrix, Inc. | DRY POWDERS OF MONOVALENT METAL CATION FOR INHALATION |
| CN107596518B (en) | 2012-02-29 | 2021-04-23 | 普马特里克斯营业公司 | Inhalable dry powder |
| AU2014248455B2 (en) | 2013-04-01 | 2018-12-06 | Pulmatrix Operating Company, Inc. | Tiotropium dry powders |
| JO3456B1 (en) | 2015-05-13 | 2020-07-05 | H Lundbeck As | ferrotioxetine pyroglutamate |
| RU2726438C2 (en) * | 2018-11-14 | 2020-07-14 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СтГМУ Минздрава России) | Method for production of a dry high protein milk mixture for prevention of osteopenia in children and adolescents with gee's disease |
| CN109453126A (en) * | 2018-12-07 | 2019-03-12 | 浙江核力欣健药业有限公司 | A kind of calcium carbonate D3Composition of chewable tablets and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5587399A (en) * | 1992-12-23 | 1996-12-24 | Abbott Laboratories | Method for preparing medical foods for the nutritional support of infants/toddlers with metabolic diseases |
| US5637313A (en) * | 1994-12-16 | 1997-06-10 | Watson Laboratories, Inc. | Chewable dosage forms |
| WO1999047122A1 (en) * | 1998-03-16 | 1999-09-23 | Smtm Group, Llc | Chewable calcium supplement and method for making it |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4650669A (en) * | 1985-07-30 | 1987-03-17 | Miles Laboratories, Inc. | Method to make effervescent calcium tablets and calcium tablets produced thereby |
| CA1297035C (en) * | 1987-12-29 | 1992-03-10 | Warner-Lambert Canada Inc. | Chewable, non-gritty calcium citrate tablet |
| US5296476A (en) * | 1989-09-08 | 1994-03-22 | Henderson Esther G | Skin care compositions |
-
2000
- 2000-04-06 SK SK498-2000A patent/SK284948B6/en not_active IP Right Cessation
-
2001
- 2001-03-15 CZ CZ20023292A patent/CZ303069B6/en not_active IP Right Cessation
- 2001-03-15 WO PCT/SK2001/000004 patent/WO2001076610A1/en not_active Ceased
- 2001-03-15 EE EEP200200584A patent/EE200200584A/en unknown
- 2001-03-15 EP EP01914325A patent/EP1274447A1/en not_active Withdrawn
- 2001-03-15 AU AU2001239668A patent/AU2001239668A1/en not_active Abandoned
- 2001-03-15 PL PL01357777A patent/PL357777A1/en not_active Application Discontinuation
- 2001-03-15 MD MDA20020265A patent/MD2722B2/en unknown
- 2001-03-15 RU RU2002130196/15A patent/RU2002130196A/en unknown
-
2002
- 2002-10-29 BG BG107227A patent/BG107227A/en unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5587399A (en) * | 1992-12-23 | 1996-12-24 | Abbott Laboratories | Method for preparing medical foods for the nutritional support of infants/toddlers with metabolic diseases |
| US5637313A (en) * | 1994-12-16 | 1997-06-10 | Watson Laboratories, Inc. | Chewable dosage forms |
| WO1999047122A1 (en) * | 1998-03-16 | 1999-09-23 | Smtm Group, Llc | Chewable calcium supplement and method for making it |
Also Published As
| Publication number | Publication date |
|---|---|
| PL357777A1 (en) | 2004-07-26 |
| MD20020265A (en) | 2003-05-31 |
| SK284948B6 (en) | 2006-03-02 |
| CZ303069B6 (en) | 2012-03-21 |
| BG107227A (en) | 2003-05-30 |
| RU2002130196A (en) | 2004-03-27 |
| EP1274447A1 (en) | 2003-01-15 |
| WO2001076610A1 (en) | 2001-10-18 |
| AU2001239668A1 (en) | 2001-10-23 |
| SK4982000A3 (en) | 2001-10-08 |
| EE200200584A (en) | 2004-04-15 |
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