JP2662764B2 - Preservative for medicinal water - Google Patents
Preservative for medicinal waterInfo
- Publication number
- JP2662764B2 JP2662764B2 JP5133021A JP13302193A JP2662764B2 JP 2662764 B2 JP2662764 B2 JP 2662764B2 JP 5133021 A JP5133021 A JP 5133021A JP 13302193 A JP13302193 A JP 13302193A JP 2662764 B2 JP2662764 B2 JP 2662764B2
- Authority
- JP
- Japan
- Prior art keywords
- preservative
- bath
- water
- medicinal
- crude drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims description 24
- 239000003755 preservative agent Substances 0.000 title claims description 17
- 230000002335 preservative effect Effects 0.000 title claims description 17
- -1 polyhexamethylene Polymers 0.000 claims description 5
- 239000004480 active ingredient Substances 0.000 claims description 3
- JFBJUMZWZDHTIF-UHFFFAOYSA-N chloro chlorite Chemical compound ClOCl=O JFBJUMZWZDHTIF-UHFFFAOYSA-N 0.000 claims description 2
- 239000003814 drug Substances 0.000 description 15
- 229940079593 drug Drugs 0.000 description 15
- 230000000052 comparative effect Effects 0.000 description 6
- 244000005700 microbiome Species 0.000 description 6
- 239000013040 bath agent Substances 0.000 description 4
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical compound ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 description 4
- 230000004075 alteration Effects 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 235000002767 Daucus carota Nutrition 0.000 description 2
- 244000000626 Daucus carota Species 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- 235000006679 Mentha X verticillata Nutrition 0.000 description 2
- 235000002899 Mentha suaveolens Nutrition 0.000 description 2
- 235000001636 Mentha x rotundifolia Nutrition 0.000 description 2
- 235000006484 Paeonia officinalis Nutrition 0.000 description 2
- 235000013832 Valeriana officinalis Nutrition 0.000 description 2
- 244000126014 Valeriana officinalis Species 0.000 description 2
- 125000003118 aryl group Chemical group 0.000 description 2
- DMSMPAJRVJJAGA-UHFFFAOYSA-N benzo[d]isothiazol-3-one Chemical compound C1=CC=C2C(=O)NSC2=C1 DMSMPAJRVJJAGA-UHFFFAOYSA-N 0.000 description 2
- 239000000645 desinfectant Substances 0.000 description 2
- 230000006866 deterioration Effects 0.000 description 2
- 230000007721 medicinal effect Effects 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 235000016788 valerian Nutrition 0.000 description 2
- 240000004731 Acer pseudoplatanus Species 0.000 description 1
- 235000002754 Acer pseudoplatanus Nutrition 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 241000086254 Arnica montana Species 0.000 description 1
- 235000002567 Capsicum annuum Nutrition 0.000 description 1
- 240000004160 Capsicum annuum Species 0.000 description 1
- 235000007866 Chamaemelum nobile Nutrition 0.000 description 1
- 244000223760 Cinnamomum zeylanicum Species 0.000 description 1
- 235000015655 Crocus sativus Nutrition 0.000 description 1
- 244000124209 Crocus sativus Species 0.000 description 1
- 240000006927 Foeniculum vulgare Species 0.000 description 1
- 235000004204 Foeniculum vulgare Nutrition 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 241000282620 Hylobates sp. Species 0.000 description 1
- 241000721662 Juniperus Species 0.000 description 1
- 244000042664 Matricaria chamomilla Species 0.000 description 1
- 235000007232 Matricaria chamomilla Nutrition 0.000 description 1
- 241001529735 Melissa Species 0.000 description 1
- 241000736199 Paeonia Species 0.000 description 1
- 244000170916 Paeonia officinalis Species 0.000 description 1
- 241000282577 Pan troglodytes Species 0.000 description 1
- 241000237509 Patinopecten sp. Species 0.000 description 1
- 235000006485 Platanus occidentalis Nutrition 0.000 description 1
- 244000178231 Rosmarinus officinalis Species 0.000 description 1
- 235000014426 Schisandra repanda Nutrition 0.000 description 1
- 240000001315 Schisandra repanda Species 0.000 description 1
- 239000005708 Sodium hypochlorite Substances 0.000 description 1
- 244000273928 Zingiber officinale Species 0.000 description 1
- 235000006886 Zingiber officinale Nutrition 0.000 description 1
- 240000003307 Zinnia violacea Species 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 235000017803 cinnamon Nutrition 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 229940009976 deoxycholate Drugs 0.000 description 1
- KXGVEGMKQFWNSR-LLQZFEROSA-N deoxycholic acid Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 KXGVEGMKQFWNSR-LLQZFEROSA-N 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 235000008397 ginger Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- SATVIFGJTRRDQU-UHFFFAOYSA-N potassium hypochlorite Chemical compound [K+].Cl[O-] SATVIFGJTRRDQU-UHFFFAOYSA-N 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000012113 quantitative test Methods 0.000 description 1
- 235000013974 saffron Nutrition 0.000 description 1
- 239000004248 saffron Substances 0.000 description 1
- 235000020637 scallop Nutrition 0.000 description 1
- SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
- Cosmetics (AREA)
Description
【0001】[0001]
【産業上の利用分野】本発明は薬湯用防腐剤に関し、更
に詳しくは生薬成分を含有する薬湯において微生物増殖
抑制のため使用される薬湯用防腐剤に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a preservative for medical water, and more particularly, to a preservative for medical water used for controlling microbial growth in a medical water containing a crude drug component.
【0002】[0002]
【従来の技術】従来、浴湯用の殺菌剤として次亜塩素酸
ナトリウム、次亜塩素酸カリウム等が広く使用されてい
る。しかし、浴用剤として特に生薬成分を含有した浴用
剤を使用した薬湯では、殺菌剤の次亜塩素酸類を使用す
ると次亜塩素酸と生薬成分とが反応してしまい、次亜塩
素酸の殺菌力が低下する。その結果浴湯中の微生物が繁
殖し浴湯が腐敗し、悪臭が出る。また、生薬成分も次亜
塩素酸で酸化され変色を起こし、生薬成分の薬効が維持
できないという問題を生じていた。2. Description of the Related Art Conventionally, sodium hypochlorite, potassium hypochlorite and the like have been widely used as disinfectants for bath water. However, in the case of a bath using a bath agent containing a crude drug component as a bath agent, hypochlorous acid reacts with the crude drug component when hypochlorous acid is used as a disinfectant, and the bactericidal activity of hypochlorous acid is reduced. Decrease. As a result, microorganisms in the bath breed and the bath rots, giving off a bad smell. Further, there has been a problem that the crude drug component is oxidized by hypochlorous acid and discolored, so that the medicinal effect of the crude drug component cannot be maintained.
【0003】[0003]
【発明が解決しようとする課題】従って、生薬成分を含
有した浴湯において微生物の繁殖を抑制し、かつ生薬成
分と反応しない薬湯用防腐剤が望まれていた。本発明者
らはホ゜リヘキサメチレンヒ゛ク゛アニト゛ヒト゛ロクロライト゛を生薬成分を含有す
る薬湯の防腐剤として使用すると、微生物の繁殖を抑え
生薬成分の変質がなく、長期にわたり浴用剤の薬効、浴
湯の色を保つことができることを見い出した。Accordingly, there has been a need for a preservative for a medicinal bath that suppresses the growth of microorganisms and does not react with the crude drug component in a bath water containing the crude drug component. The present inventors use polyhexamethylene polyanito (human chlochlorite) as a preservative for a medicinal water containing a crude drug component, suppress the growth of microorganisms, do not deteriorate the crude drug component, and maintain the medicinal properties of the bath agent and the color of the bath water for a long time. I found what I could do.
【0004】[0004]
【課題が解決するための手段】すなわち本発明は、ホ゜リヘ
キサメチレンヒ゛ク゛アニト゛ヒト゛ロクロライト゛を有効成分とする薬湯用防腐
剤に関する。That is, the present invention relates to a preservative for medicinal water containing polyhexamethylene polyanito-human-rochlorite as an active ingredient.
【0005】[0005]
【作用】ここにおいて薬湯とは、生薬成分を含有した浴
用剤を使用した浴湯のことである。生薬成分としてはソ
ウジュツ、ビャクジュツ、カノコソウ、ケイガイ、コウ
ボク、センキュウ、トウキ、ショウキョウ末、ニンジ
ン、ケイヒ、シャクヤク、ハッカ葉、オウゴン、サンシ
シ、ブクリョウ、ドクカツ、ショウブ、ガイヨウ、マツ
ブサ、ビャクシ、ジュウヤク、ショウノウ、サフラン、
オウバクエキス、チンピ、ウイキョウ、カン皮末、カミ
ツレ、メリッサ、ローズマリー、マロニエ、アルニカ等
が挙げられる。In the present invention, the medicinal bath is a bath using a bath agent containing a crude drug component. The crude drug components include soybean, zinnia, valerian, scallop, sycamore, senkyu, touki, ginger, end of carrot, cinnamon, peonies, mint leaves, gibbon, sanshishi, bakuryo, dokatsu, shobu, gaiyou, matsubusa, juniper, japonicus ,saffron,
Oubak extract, chimpanzee, fennel, canned powder, chamomile, melissa, rosemary, marronnier, arnica and the like.
【0006】本発明の薬湯用防腐剤として用いられるホ゜
リヘキサメチレンヒ゛ク゛アニト゛ヒト゛ロクロライト゛はアイシー・アイ・ジャパ
ン(株)より商品名”Proxel IB”で販売され
ている化合物である。また、この化合物は一般式、[0006] Polyhexamethylene polyanito-human chlorochlorite used as the preservative for medicinal water of the present invention is a compound sold by ICI Japan Co., Ltd. under the trade name "Proxel IB". The compound has the general formula:
【0007】[0007]
【化1】 で示される。Embedded image Indicated by
【0008】この化合物を有効成分とする本発明の防腐
剤の使用方法に関して云えば、薬湯となる生薬成分の種
類、濃度により異なり一概に云えないが、薬湯用防腐剤
の濃度は0.1から1%程度に希釈し、この時pH4.0から5.5
で無色から淡黄色の性状を有する液体である。その希釈
した物を浴湯に対して概ね100から500ppmとなるように
添加すればよい。また、必要に応じてこの薬湯用防腐剤
に、防腐剤、ビタミン剤、界面活性剤、香料、色素等配
合剤を配合して使用してもよい。The method of using the preservative of the present invention containing this compound as an active ingredient varies depending on the type and concentration of the crude drug component to be a medicinal bath, and cannot be specified without any limitation, but the concentration of the preservative for the medicinal bath is 0.1 to 1%. Diluted to about pH 4.0 to 5.5
Is a colorless to pale yellow liquid. What is necessary is just to add the diluted thing so that it may become about 100-500 ppm with respect to bath water. If necessary, a preservative, a vitamin, a surfactant, a fragrance, a coloring agent and the like may be blended with the preservative for medicinal water.
【0009】添加量に関しては100ppmより少ないと微生
物繁殖の抑制力が低く、それと反対に500ppmより多いと
微生物繁殖の抑制力は高いが眼等粘膜に対する刺激があ
るため好ましくない。When the amount of addition is less than 100 ppm, the ability to inhibit the growth of microorganisms is low. On the contrary, when it is more than 500 ppm, the ability to inhibit the growth of microorganisms is high, but undesirably irritates the mucous membranes such as eyes.
【0010】[0010]
【実施例】 以下に実施例
を挙げて更に詳しく本発明を説明するが、本発明はそれ
らに限定されるものではない。EXAMPLES Hereinafter, the present invention will be described in more detail by way of examples, but the present invention is not limited thereto.
【0011】(実施例1〜3、比較例1)公衆浴場で41℃の
カノコソウ、ケイガイ、ハッカ葉、チンピの成分が1500
ppmの薬湯500mlを500mlのサンプル瓶5本に採取した。そ
れに本発明ホ゜リヘキサメチレンヒ゛ク゛アニト゛ヒト゛ロクロライト゛(アイ・シー
・アイ・ジャパン(株)社製、商品名”ProxelI
B”)5mg、15mg、25mgを加え、順に実施例1(100ppm)、
実施例2(300ppm)、実施例3(500ppm)とした。同様に、
比較例として本発明の防腐剤を加えない薬湯を使用し、
それらを40℃の恒温室に保存し、経時的に試験管に20ml
ずつ採取して、薬湯の香りを調べた。比較例の結果とし
て0.8日後には異なる臭いを感じた。それを表1に示
す。また、水道法に基づく日本水道協会による上水試験
法で0.8日後に大腸菌数を測定をした。尚、大腸菌の定
量試験は、同試験法にてデオキシコール酸塩寒天培地に
よる方法で行った。結果は表2に示す。(Examples 1-3, Comparative Example 1) In a public bath, the components of valerian, kayak, mint leaf, and chimney at 41 ° C were 1500
500 ml of the medicinal water of ppm was collected in five 500 ml sample bottles. In addition, the polyhexamethylene polyanit human hydrochlorite of the present invention (trade name "Proxel I" manufactured by ICI Japan Ltd.)
B ") 5 mg, 15 mg and 25 mg were added, and Example 1 (100 ppm),
Example 2 (300 ppm) and Example 3 (500 ppm). Similarly,
As a comparative example, using a medicinal water without adding the preservative of the present invention,
Store them in a constant temperature room at 40 ° C and add 20 ml
Each was sampled and examined for the smell of the medicinal water. As a result of the comparative example, a different smell was felt after 0.8 days. It is shown in Table 1. In addition, the number of E. coli was measured 0.8 days later by the water supply test method of the Japan Water Works Association based on the Water Supply Law. In addition, the quantitative test of Escherichia coli was carried out by the same test method using a deoxycholate agar medium. The results are shown in Table 2.
【0012】[0012]
【表1】 − ---- 変質無し ± ---- 殆ど変質無し(少し異なる臭いを感じる、芳香
臭がややうすい) + ---- 少し変質(異なる臭いを感じる、芳香臭がうす
い) ++ ---- 変質(腐敗臭で、不快感を感じる) +++ ---- 変質(腐敗臭が強く、不快感が強い)[Table 1] ----- No alteration ± ---- Almost no alteration (feels a little different smell, slightly aromatic odor) + ---- Slight alteration (feels different odor, slightly aromatic odor) ++ --- -Deterioration (feeling of discomfort due to putrefaction odor) ++ ---- Deterioration (strong odor of decay, strong discomfort)
【0013】[0013]
【表2】 [Table 2]
【0014】(実施例4、比較例2)兵庫県加古川市のA
浴場において実地試験を行った。一日の利用延べ人数約
500人、ニンジン、ケイヒ、シャクヤク、チンピの生薬
成分が2000ppmの薬湯400Lにおいて本発明の防腐剤80gを
加えた(実施例4、200ppm)。本発明の防腐剤を加えない
薬湯を比較例2とし、3日後の薬湯の臭いを調べた結
果、実施例4は異臭が殆ど無く、比較例2においては腐
敗臭が強かった。Example 4 and Comparative Example 2 A in Kakogawa City, Hyogo Prefecture
A field test was conducted in a bathhouse. Approximate number of people per day
A preservative of the present invention (80 g) was added to 400 liters of medical water containing 500 ppm of crude drug components of carrot, cayenne, peony, and chimney (Example 4, 200 ppm). The medicinal water without the preservative of the present invention was used as Comparative Example 2 and the smell of the medicinal water after 3 days was examined. As a result, Example 4 had almost no off-flavor, and Comparative Example 2 had a strong putrefaction smell.
【0015】[0015]
【発明の効果】本発明の薬湯用防腐剤は、浴用剤として
特に生薬成分を含有する薬湯において、生薬成分と反応
が無く微生物の繁殖を抑え浴湯の変質を防止する防腐剤
として非常に有益なものである。Industrial Applicability The preservative for medicinal water of the present invention is very useful as a preservative, especially in a medicinal bath containing a crude drug component, which does not react with the crude drug component, suppresses the growth of microorganisms, and prevents deterioration of the bath water. It is something.
Claims (1)
分とする薬湯用防腐剤。1. A preservative for medicinal water, comprising polyhexamethylene polyanit (human chlorochlorite) as an active ingredient.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5133021A JP2662764B2 (en) | 1993-05-10 | 1993-05-10 | Preservative for medicinal water |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5133021A JP2662764B2 (en) | 1993-05-10 | 1993-05-10 | Preservative for medicinal water |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH06321714A JPH06321714A (en) | 1994-11-22 |
| JP2662764B2 true JP2662764B2 (en) | 1997-10-15 |
Family
ID=15094947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5133021A Expired - Lifetime JP2662764B2 (en) | 1993-05-10 | 1993-05-10 | Preservative for medicinal water |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2662764B2 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106115876A (en) * | 2016-07-27 | 2016-11-16 | 柳州市明达鸽业养殖专业合作社 | Logical sequence takes off special purifying of drinking water agent of Columba livia and preparation method thereof |
| CN106115877A (en) * | 2016-07-27 | 2016-11-16 | 柳州市明达鸽业养殖专业合作社 | Purifying of drinking water agent special for Denmark Wang Ge and preparation method thereof |
| CN106241978A (en) * | 2016-07-27 | 2016-12-21 | 柳州市明达鸽业养殖专业合作社 | Purifying of drinking water agent that card slave Columba livia is special and preparation method thereof |
| CN106219695A (en) * | 2016-07-27 | 2016-12-14 | 柳州市明达鸽业养殖专业合作社 | Purifying of drinking water agent that safe deep Columba livia is special and preparation method thereof |
| CN106115878A (en) * | 2016-07-27 | 2016-11-16 | 柳州市明达鸽业养殖专业合作社 | Purifying of drinking water agent that Malta Columba livia is special and preparation method thereof |
| CN106186224A (en) * | 2016-07-27 | 2016-12-07 | 柳州市明达鸽业养殖专业合作社 | Purifying of drinking water agent special for U.S. Wang Ge and preparation method thereof |
| CN106186225A (en) * | 2016-07-27 | 2016-12-07 | 柳州市明达鸽业养殖专业合作社 | Purifying of drinking water agent that Europe meat pigeon is special and preparation method thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS579717A (en) * | 1980-06-20 | 1982-01-19 | Nippon Shinyaku Co Ltd | Germicidal composition |
| DE3542516A1 (en) * | 1985-12-02 | 1987-06-04 | Henkel Kgaa | DISINFECTANT |
| JPH0334919A (en) * | 1989-06-30 | 1991-02-14 | Hoya Corp | Bathing agent |
| JPH06104621B2 (en) * | 1990-07-20 | 1994-12-21 | 相互印刷工芸株式会社 | Bath agent |
| JP3063911B2 (en) * | 1990-09-13 | 2000-07-12 | 有限会社野々川商事 | Bath agent |
-
1993
- 1993-05-10 JP JP5133021A patent/JP2662764B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH06321714A (en) | 1994-11-22 |
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