JP6971658B2 - Child resistance seal and PTP package with it attached - Google Patents

Description

The present invention is to allow infants and elderly people to accidentally swallow or eat by a simple method of attaching to an existing Press Through Package package (hereinafter referred to as "PTP package"). (Hereinafter, such a function is referred to as "child resistance"), and the PTP package to which the sealing material is attached. Further, in detail, a seal having an emetic agent on one surface of the easily piercing and destructive substrate and having an adhesive layer formed on the other surface of the substrate, and the seal being attached to the surface of the lid material. It relates to the worn PTP package.

Accidents related to accidental ingestion and accidental ingestion by infants and the elderly have traditionally been regarded as problems. There is known a method of preventing accidental ingestion and accidental ingestion by causing a feeling of vomiting when it is contained in the mouth (see, for example, Patent Document 1).
Not only toys, but also in the packaging form called PTP packaging, which is suitable for accommodating chemicals consisting of capsules and tablets, and confectionery such as granular chocolate and ramune, the size and ease of handling of the packaging. Therefore, there have been problems such as accidental ingestion and accidental ingestion of the contents, and accidental ingestion of the cut blister pack and damage to the esophagus at sharp corners.

Therefore, by applying an emetic agent that has an emetic effect when it is contained in the mouth, the outer surface of the PTP package is also coated with an emetic agent. It is recalled to prevent the PTP package from being swallowed as it is and to prevent the esophagus from being damaged by accidental ingestion (see, for example, Patent Document 2), but the emetic agent is applied to the PTP package. The method of putting on and adhering is not a simple method, and for consumers who widely use PTP packages in their daily lives, it is a simpler method to accidentally swallow PTP packages. It is desirable to take measures to prevent accidental ingestion.

Japanese Unexamined Patent Publication No. 08-206368 Japanese Unexamined Patent Publication No. 2014-141258

The present invention has been made in view of the above circumstances, and has an emetic agent on the surface, which can impart a child resistance function while maintaining push-through property at the time of taking out the contents of the PTP package by a simple method. An object of the present invention is to provide a seal and a PTP package to which the seal is attached.

As a result of diligent research to solve the above problems, the inventors of the present application have found that the above object can be achieved by designing a seal having a specific configuration, and have completed the present invention.

That is, the present invention relates to the following seal and a PTP package in which the seal is attached to a lid material of the PTP package.

The present invention is a seal to be attached to the outer surface of a lid material of a PTP package, which has an emetic agent on one surface of an easily piercing and destructive substrate and adheres to the other surface of the substrate. A seal having a layer formed is provided.

The easily piercing and destructive substrate is preferably aluminum foil and / or paper.

It is preferable that the emetic agent on one surface of the substrate is a smeared emetic agent.

It is preferable that the adhesive layer is an adhesive layer provided on a part of the base material surface.

The emetic agent is preferably denatonium benzoate.

A PTP package having a bottom material having a plurality of recesses for accommodating the contents and a lid material attached to the upper surface of the bottom material to keep the contents confidential in the recesses. Provided is a PTP package in which the adhesive layer surface of the seal is attached to the outer surface of the package of the lid material.

According to the seal of the present invention, the existing PTP package can be easily taken out (push-through property) of the existing PTP package by a simple method of sticking, and the action of the emetic agent on the surface of the seal can be used. If an elderly person or an infant accidentally puts it in the mouth, it is possible to prevent accidental ingestion or accidental ingestion of the PTP package by encouraging it to be exhaled outside the body. Then, it has the effect of being able to provide such a PTP package having a so-called child resistance function.

It is sectional drawing which shows the layer composition example of a seal. It is a top view from the side of the adhesive layer of the seal which is the aspect which does not form the adhesive layer in the portion corresponding to the concave part of the bottom material of the PTP package to be attached in the adhesive layer of a seal.

Hereinafter, the present invention will be described based on a preferred embodiment.

The seal of the present invention is a seal used by being attached to the outer surface of a lid material of a PTP package, and has an emetic agent on one surface of an easily piercing and destructible substrate, and is used for the substrate. It is a seal having a viscous adhesive layer formed on the other surface.

The easily piercing and destructive base material is made of a material that can be easily torn (push-through) by extruding the contents of the PTP package, for example, a metal foil (aluminum foil, etc.), a metal thin film, or the like. It is composed of metal, paper such as glassin paper, vinyl chloride resin, polypropylene and polyethylene, olefin resin such as cyclic olefin resin, ester resin, amide resin, styrene resin, etc. There may be.

From the viewpoint of push-through property, the easily piercing and destructive substrate is ^{preferably one having a burst strength of 0.01 to 5 kg / cm 2} by the method according to the JIS P8112 Mullen low pressure test, and more preferably 0.1. ~ 3.5 kg / cm ² . Further, it is preferable that the piercing strength measured according to the piercing strength test of JIS Z1707 is 1 to 5N, and further, considering the case where the PTP package is for elderly people and infants, piercing It is more preferable that the strength is 1 to 3N.

As a base material containing a resin-based material, for example, a uniaxially stretched polypropylene film, a uniaxially stretched polyethylene terephthalate film, a uniaxially stretched polyethylene naphthalate film, or the like can be used. Further, since the resin film blended with an inorganic powder such as talc has good breakability, it can be used as an easily piercing and destructive base material.

It is particularly preferable to use aluminum foil and / or paper as the easily piercing and destructive base material because of its excellent push-through property.

The aluminum foil as the base material may be, for example, a material having a thickness of 10 to 30 μm and generally usable as a lid material for a PTP package, and more preferably 15 to 20 μm aluminum having excellent push-through property. Foil is preferred. Hard or soft aluminum foil can be used.

As the base paper, any paper that can be pushed through can be used. For example, various types of paper such as glassin paper, imitation paper, clay coated paper, kraft paper, paperboard, and synthetic paper can be used.
The thickness of these paper base materials can be appropriately changed according to the material so that the strength, heat resistance, and breakability (push-through property) when taking out the contents are appropriate. , Basis weight, 30 g / m ² or more and 80 g / m ² or less are preferable, and 40 g / m ² or more and 60 g / m ² or less are more preferable.
As a result, it is said that it is excellent not only in strength as a sealing base material and breakability when taking out the contents (push-through property), but also in mechanical suitability, concealment property when printing, and design properties such as high whiteness. Has advantages.
If the thickness of the paper base material is less than the above range, the required rigidity cannot be obtained, and the mechanical suitability and concealment property are inferior, which is not preferable. If the thickness exceeds the above range, it is not preferable because it is difficult to tear even if the contents are pierced after being attached to the PTP package and the push-through property is inferior.

Examples of the easily piercing and destructive base material having a laminated structure include an aluminum foil laminate, and specifically, a material obtained by laminating a synthetic resin sheet such as polystyrene or polyethylene terephthalate on one or both sides of an aluminum foil may be used. can.
As the easily piercing and destructive base material having a laminated structure, a sheet made of a thermoplastic resin such as a polyethylene resin, a polypropylene resin, a polystyrene resin, a polyethylene terephthalate resin, or a cyclic polyolefin resin, and a vapor-deposited film laminated can be used. As the vapor deposition film, for example, a vapor deposition film made of aluminum, aluminum oxide, or silicon oxide is used. The thickness of the thin-film deposition film is not particularly limited, but is preferably in the range of 10 to 100 nm and is used.
The thickness of the easily piercing and destructive substrate in the laminated structure is not particularly limited, but is, for example, 10 to 50 μm.

The easily piercing destructive substrate can be printed with characters or designs on one or both sides. It is also a preferable form that words, marks, etc. that can be recognized as a member for the purpose of preventing accidental ingestion and accidental ingestion by the elderly and infants are printed.
Printing can be performed by a conventionally known printing method, for example, inkjet printing, gravure printing, or the like. The ink used for printing is not particularly limited, but it is preferable to use a UV curable type or the like in addition to the thermosetting type.

The structure of the seal will be described with reference to FIG.
If necessary, a colorless or colored transparent coating agent can be applied to the surface on which the print 13 of the easily piercing and destructive base material 10 is applied, particularly to the outer surface, and printing of characters, designs, etc. An OP (overprint) coat layer 14 for the purpose of preventing peeling off or rubbing and protecting the surface can be provided.
The OP coat layer 14 can be formed of the one conventionally used for the overprint layer of the PTP package.
The OP coating layer 14 can be formed by applying, for example, an OP coating agent made of a transparent resin such as nitrocellulose, acrylic, or epoxy with a gravure coat or the like. The thickness of the OP coat layer 14 is not particularly limited, but is preferably 0.5 to 3.0 μm. The OP coat layer may contain a matting agent such as silicon oxide in an amount of about 1 to 5% by mass.
When a coating film containing the emetic agent 11 is provided on the OP coat layer 14, the OP coat layer 14 is formed uniformly and uniformly so that the coating film containing the emetic agent 11 does not repel. It is preferable that the surface is not water repellent. Further, the adhesive layer 12 can be provided on the easily piercing and destructive base material 10, and a release sheet layer (not shown) can be further provided on the adhesive layer as described later. ..

The adhesive layer is a layer for attaching the seal of the present invention to a PTP package.
The adhesive that constitutes the adhesive layer is not particularly limited, and a general adhesive that is widely known in the art can be used. It is preferable to use known natural rubber-based, synthetic rubber-based, acrylic resin-based, and urethane resin-based adhesive adhesive materials. Among them, an acrylic resin-based adhesive having an acrylic copolymer as a main component is suitable because various adhesive physical properties such as adhesive strength can be easily adjusted by using a monomer composition, a molecular weight, and a cross-linking reaction. Used.

If necessary, various additives such as a tackifier resin, an antioxidant, an ultraviolet absorber, a filler, a pigment, and a thickener may be added to the adhesive layer as long as the performance is not impaired.

The adhesive layer may be provided on the entire surface of the sealing base material surface or may be provided on a part of the sealing base material surface. Considering the push-through property of the PTP package after the seal is attached, the adhesive layer should not be formed on the seal base material in the portion corresponding to the recess of the bottom material of the PTP package to which the seal is attached. (See FIG. 2: FIG. 2 shows a plan view of the seal provided with the portion 15 on which the adhesive layer is not formed, as viewed from the adhesive layer side). Considering the adhesiveness of the seal to the PTP package and sufficient adhesiveness, it is preferable that the seal is provided on the entire surface of the seal base material.
When the adhesive layer is provided on a part of the sealing base material, it is preferable to consider the method of forming the adhesive layer and select a suitable adhesive.

The method of applying the adhesive is not particularly limited, and a predetermined coating method on the substrate is used using a general coating machine such as a bar coater, a roll coater, a comma coater, a die coater, and a hot melt coater. A so-called direct coating method may be adopted in which the adhesive layer is formed after the coating is applied directly to the surface of the surface, or after the coating is applied on the release sheet to form the adhesive layer. A so-called transfer method, in which transfer is performed on a predetermined surface on the substrate, may be adopted.

The amount of the adhesive adhesive applied is not particularly limited, but is preferably 3 to 100 g / m ² in terms of solid content, more preferably 5 to 75 g / m ² , and more preferably 20 to 60 g. It is preferably / m ^2. If the coating amount of the adhesive is ^{less than 3 g / m 2} , sufficient adhesive force to the PTP package may not be obtained, and conversely, if it ^{exceeds 100 g / m 2} , push-through property is obtained. May decrease.

In the seal of the present invention, the release sheet layer may be laminated on the adhesive layer for the purpose of protecting the seal until use, particularly for the purpose of protecting the adhesive layer, or the adhesive layer. This is a preferred embodiment from the viewpoint of manufacturing and laminating on a sealing base material.
The release sheet layer may be any material as long as it protects the adhesive layer and is easily peeled off at the time of peeling. A release sheet may be a resin alone such as an olefin resin or a polyester resin, or a release sheet having a resin sheet or paper as a support and having a release layer containing, for example, a silicone compound on the support.

When the seal having the release sheet layer is attached to the PTP package, the release sheet layer is peeled off from the seal to expose the adhesive layer, and the seal is attached to the PTP package to which the child resistance function is to be imparted. ..

The seal of the present invention has an emetic agent on one surface on an easily piercing and destructive substrate.
Here, having an emetic agent on one surface of the substrate means that the emetic agent is applied to one surface of the substrate by using a paint containing or not containing an emetic agent and a component serving as a binder. To form a coating film containing an emetic agent, to adhere the emetic agent to the surface on the substrate via a component serving as a binder, a film or a thin layer having the emetic agent on the surface, a semi-permeable film, etc. It includes laminating and the like.
As the binder, either an organic material or an inorganic material can be used, and the organic material is not particularly limited, but in the organic material, for example, nitrocellulose type, acrylic type, epoxy type, urethane type, ester type, etc. As known resin and inorganic materials such as alkyd-based, olefin-based, vinyl chloride-based, melamine-based, and phenol-based materials, for example, known materials such as silicone-based, silicon-based, and other ceramic-based materials can be used.

Applying the emetic agent on the substrate is one of the preferred embodiments.
For example, in a state where the emetic agent is dissolved in a solvent to form a solution, the OP-coated surface on the printed surface of the printed aluminum foil is coated with a gravure roll and dried to evaporate the solvent to evaporate the emetic agent. Can be placed on the surface on the substrate.

The emetic agent may be applied to the entire surface of one side of the base material, or may be applied to at least a part of the base material, and is a seal when applied to the PTP package. It suffices if it is applied to the entire surface or at least a part of the outer surface.

Emetics include bitterness emetics, sour emetics, pungent emetics, etc., which have an emetic effect when taken in the mouth, are not toxic, and have established safety such as food additives. If so, a material made of a well-known material can be adopted. In terms of emetic action, a bitterness emetic agent is effective, and for example, compounds such as terpenes, xanthine derivatives, alkaloids, terpene glycosides, and triterpenoid derivatives can be adopted. Specifically, denatonium benzoate, octaacetylated sugar, hops, caffeine, kawaratake extract, kiku extract, kihada extract, spice extract, himematsutake extract, reishi extract, naringin enzyme-treated product, dimetoki Strikinine Brucin (Brusin), Humlone, Lupron, Isohumulone, Luptrion, Natural Caffeine, Synthetic Caffeine, Kinin, Kinidin, Cinconin, Tannin, Kiraya Saponin, Kiraya Sapogenin, Kiraya Acid, Belverin, Genthiopicrin, Limonin, Theobromine, Narindin , Flabanone, Cassiine, Neo-Cassine, Nigaquinone A to L, Nigaquinone, Piclasin A to G, Methyl Nigaquinone, Abcintin, Bolapetside, Bolaptor, Methylthioadenosine, Caffeine and the like can be adopted. Citric acid, tartaric acid, lactic acid, acetic acid, glacial acetic acid, fumaric acid, sodium fumarate, malic acid, adipic acid, etc. can be used as the acid emetic agent, and piperin, chavicine, capsaicin, α-sansho as the spicy emetic agent. All, β-sanshool, zingeron, chavicine, isothiocyanate, and the like can be adopted.

Suitable emetic agents include denatonium benzoate in consideration of emetic action and safety. Examples of the solvent for denatonium benzoate include methanol and ethanol.

The PTP package to which the seal of the present invention is attached is not particularly limited as long as it is a PTP package widely known in the art. A PTP package having a so-called bottom material having a plurality of recesses for accommodating the contents and a so-called lid material which is attached to the upper surface of the bottom material and holds the contents airtightly in the recesses. Anything may be used as long as it is used.

The bottom material of the PTP package is a long strip-shaped sheet material in which a large number of recesses large enough to accommodate the contents are formed in a matrix by vacuum forming or vacuum forming, for example, 2 rows and 5 columns. It is manufactured by cutting the sheet material so that 10 recesses are arranged in the above. The shape of the concave portion can be appropriately set according to the shape of the contents, and can be formed into a circular shape, an elliptical shape, an oval shape, or a rectangular shape, for example, in a plan view. The number of recesses formed in one bottom material can be arbitrarily set according to the number of contents to be contained in the PTP package.

The bottom material is made from well-known synthetic resin materials such as polyethylene terephthalate (PET), polypropylene (PP), polyethylene (PE), ethylene-vinyl alcohol copolymer resin (EVOH), nylon (NY), and polyvinyl chloride (PVC). However, it is made of a transparent synthetic resin sheet material that has excellent gas barrier properties and allows the contents to be seen through from the bottom material side so that foreign matter can be easily inspected into the recesses. It is preferable to configure it. Specifically, it is preferably composed of PP or PVC.

As the lid material, various materials shown in the description of the easily piercing and destructive base material in the seal of the present invention can be used.
A printing and / or OP coat layer already known in the art can also be provided on the lid material in the same manner as the easily piercing and destructive substrate. In addition, various functional layers in the already known PTP package can be formed as long as the function of the PTP package is not impaired. It is also possible to provide a heat seal layer or a viscous adhesive layer that firmly adheres the bottom material and the lid material.

The seal of the present invention is used by being attached to a lid material of a PTP package, and has sufficient adhesiveness to various materials constituting the lid material.
The shape of the seal may be cut out, punched, etc. in advance according to the shape of the PTP packaging body lid material to be attached, or it is required from a single-wafered or rolled-up seal. Only the area may be cut out and pasted.

In the present invention, the seal described above is attached to a bottom material having a plurality of recesses for accommodating the contents and the upper surface of the bottom material to airtightly hold the contents in the recesses of the bottom material. It contains a PTP package obtained by attaching the PTP package having a lid material to the outer surface of the package of the lid material.
The PTP package of the present invention includes the PTP package to which the child resistance function as described above is imparted.

Hereinafter, one embodiment of the present invention will be shown. The present invention is not limited to these.

Example: An OP (overprint) coat layer generally used for a lid material of a PTP package is used on a printed surface of a gravure-printed aluminum foil (thickness 17 μm: piercing strength of about 2 N) using a gravure roll. A solution of denatonium benzoate (emetic agent) dissolved at a concentration of 10 ppm using methanol as a solvent was applied on the OP coat layer by gravure roll and dried. The solvent was evaporated by allowing the emetic agent to be placed on the surface of the substrate.
Further, on the other surface of the aluminum foil, a viscous adhesive layer made of an acrylic pressure-sensitive adhesive was formed by a comma coater (solid content coating amount: 50 g / m ² ). By such a method, a seal which is a specific example of the present invention was produced.

Using the seal produced by the above method, on the outer surface of the lid material of an existing PTP package (for example, 5 protruding parts of the bottom material x 2 rows, plane size 4 cm x 10 cm, contents: chemical capsule). On the other hand, when the adhesive layer surface of the sheet-fed seal whose plane dimensions were adjusted in advance was attached by hand and the take-out property (push-through property) of the contents was evaluated (test in which a person actually takes it out), the existing one. Although it required a stronger force than the PTP package, it was confirmed that the push-through property was maintained and the contents could be taken out. The average value (n = 3) of the piercing strength of the lid material in the existing PTP package used is 2.3N, and only the lid material of the existing PTP package and the seal of the present invention are overlapped. The average value (n = 3) of the piercing strength of the laminated body was 3.8N.

The push-through property when the seal of the present invention is attached is at a level that can be sufficiently used as a PTP package, and in the sense of preventing unnecessary removal of the contents by an infant, a slightly strong force is applied at the time of removal. It can be said that what is required is in line with the purpose of the seal of the present invention.
Regarding the feeling of vomiting to prevent accidental ingestion and accidental ingestion, the PTP package to which the seal of the present invention is affixed can feel sufficient bitterness when it is contained in the mouth, and a PTP package having an emetic effect can be obtained. Has been done.

Although the embodiments of the present invention have been described above, the present invention is not limited to the above-described embodiments, and it is needless to say that the configuration thereof can be changed without departing from the gist of the present invention. be.

100, 200 ... Seal, 10 ... Easy piercing destructive substrate, 11 ... Emetic agent, 12 ... Adhesive layer, 13 ... Printing (layer), 14 ... OP (overprint) coat layer, 15 ... Adhesive layer The part that does not form

Claims (7)

A seal to be attached to the outer surface of the lid material of a blister pack, having an emetic agent on one surface of an easily piercing and destructive substrate, and forming an adhesive layer on the other surface of the substrate. Seal. The seal according to claim 1, wherein the easily piercing destructive substrate is aluminum foil and / or paper. The seal according to claim 1 or 2, wherein the emetic agent on one surface of the substrate is a smeared emetic agent. The seal according to any one of claims 1 to 3, wherein the adhesive layer is an adhesive layer provided on a part of a base material surface. The seal according to any one of claims 1 to 4, wherein the emetic agent is denatonium benzoate. A PTP package having a bottom material having a plurality of recesses for accommodating the contents and a lid material attached to the upper surface of the bottom material to airtightly hold the contents in the recesses of the bottom material. A PTP package in which the adhesive layer surface of the seal according to any one of claims 1 to 5 is attached to the outer surface of the package of the lid material. The PTP package according to claim 6, wherein the piercing strength is 3.8 N or more.

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