NO332405B1 - Forbindelse av 5-substituerte kinolin- og isokinolinderivater, fremgangsmate for deres fremstilling, deres anvendelse til fremstilling av farmasoytiske midler for behandling av inflammatorisk sykdom og farmasoytisk preparat omfattende forbindelsen. - Google Patents

Forbindelse av 5-substituerte kinolin- og isokinolinderivater, fremgangsmate for deres fremstilling, deres anvendelse til fremstilling av farmasoytiske midler for behandling av inflammatorisk sykdom og farmasoytisk preparat omfattende forbindelsen.

Info

Publication number: NO332405B1
Authority: NO; Norway
Prior art keywords: compound; preparation; treatment; inflammatory disease; pharmaceutical composition
Prior art date: 2004-11-12

Application number

NO20072963A

Other languages

English (en)

Norwegian (no)

Other versions

NO20072963L (no

Inventor

Werner Skuballa

Orlin Petrov

Heike Schacke

Matthias Schneider

Hartmut Rehwinkel

Norbert Schmees

Stefan Jaroch

Jan Huebner

Christian Dinter

Original Assignee

Bayer Pharma AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-11-12

Filing date

2007-06-11

Publication date

2012-09-10

2005-04-26 Priority claimed from DE102005020331A external-priority patent/DE102005020331A1/de

2007-06-11 Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG

2007-08-03 Publication of NO20072963L publication Critical patent/NO20072963L/no

2012-09-10 Publication of NO332405B1 publication Critical patent/NO332405B1/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Hematology (AREA)
Dermatology (AREA)
Endocrinology (AREA)
Ophthalmology & Optometry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20072963A 2004-11-12 2007-06-11 Forbindelse av 5-substituerte kinolin- og isokinolinderivater, fremgangsmate for deres fremstilling, deres anvendelse til fremstilling av farmasoytiske midler for behandling av inflammatorisk sykdom og farmasoytisk preparat omfattende forbindelsen. NO332405B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE102004055633A DE102004055633A1 (de)	2004-11-12	2004-11-12	5-substituierte Chinolin- und Isochinolin-Derivate, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
DE102005020331A DE102005020331A1 (de)	2005-04-26	2005-04-26	5-substituierte Chinolin- und Isochinolin-Derivate, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
PCT/EP2005/012531 WO2006050998A1 (de)	2004-11-12	2005-11-11	5-substituierte chinolin- und isochinolin-derivate; ein verfahren zu ihrer herstellung und ihre verwendung als entzündungshemmer

Publications (2)

Publication Number	Publication Date
NO20072963L NO20072963L (no)	2007-08-03
NO332405B1 true NO332405B1 (no)	2012-09-10

Family

ID=35613753

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20072963A NO332405B1 (no)	2004-11-12	2007-06-11	Forbindelse av 5-substituerte kinolin- og isokinolinderivater, fremgangsmate for deres fremstilling, deres anvendelse til fremstilling av farmasoytiske midler for behandling av inflammatorisk sykdom og farmasoytisk preparat omfattende forbindelsen.

Country Status (30)

Country	Link
EP (1)	EP1844039B1 (sr)
JP (1)	JP4460608B2 (sr)
KR (1)	KR101168462B1 (sr)
CN (1)	CN101124220B (sr)
AR (1)	AR051767A1 (sr)
AU (1)	AU2005303926B2 (sr)
BR (1)	BRPI0517797A (sr)
CA (1)	CA2586689C (sr)
CY (1)	CY1110520T1 (sr)
DE (2)	DE102004055633A1 (sr)
DK (1)	DK1844039T3 (sr)
EA (1)	EA013076B1 (sr)
ES (1)	ES2329599T3 (sr)
GT (1)	GT200500330A (sr)
HR (1)	HRP20090509T1 (sr)
IL (1)	IL182933A (sr)
ME (2)	MEP13608A (sr)
MX (1)	MX2007005736A (sr)
MY (1)	MY141780A (sr)
NO (1)	NO332405B1 (sr)
NZ (1)	NZ555064A (sr)
PA (1)	PA8652701A1 (sr)
PE (1)	PE20061052A1 (sr)
PL (1)	PL1844039T3 (sr)
PT (1)	PT1844039E (sr)
RS (2)	RS51161B (sr)
SI (1)	SI1844039T1 (sr)
TW (1)	TWI311559B (sr)
UY (1)	UY29213A1 (sr)
WO (1)	WO2006050998A1 (sr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7402596B2 (en)	2005-03-24	2008-07-22	Renovis, Inc.	Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
TWI464148B (zh)	2006-03-16	2014-12-11	Evotec Us Inc	作為ｐ２ｘ7調節劑之雙環雜芳基化合物與其用途
CN101484187B (zh) *	2006-07-07	2012-12-26	博士伦公司	包含解离的糖皮质激素受体激动剂和免疫抑制剂的用于治疗干眼症的组合物
BRPI0714815A2 (pt) *	2006-08-07	2013-05-21	Bausch & Lomb	composiÇço, e, uso de um (a) agonista e (b) um agente anti-infeccioso
ATE531366T1 (de) *	2006-08-07	2011-11-15	Bausch & Lomb	Zusammensetzungen und verfahren zur behandlung, verminderung, verbesserung oder linderung von erkrankungen des hinteren augensegments
EP2397140A1 (en) *	2006-08-31	2011-12-21	Bausch & Lomb Incorporated	Compositions and methods for treating or preventing glaucoma or progression thereof
US20110105559A1 (en) *	2006-09-11	2011-05-05	Rohrs Brian R	Compositions and Methods for Treating, Controlling, Reducing, Ameliorating, or Preventing Allergy
US20110104159A1 (en) *	2006-09-11	2011-05-05	Rohrs Brian R	Compositions and methods for treating, controlling, reducing, ameliorating, or preventing allergy
DK2061444T3 (da) *	2006-09-11	2011-06-27	Bausch & Lomb	Sammensætninger og fremgangsmåder til behandling, kontrol, reducering, forbedring eller forebyggelse af allergi
KR20090077946A (ko) *	2006-11-09	2009-07-16	보오슈 앤드 롬 인코포레이팃드	특정 치환된 알코올의 선택된 입체이성질체의 합성
EP1982976A1 (en) *	2007-04-18	2008-10-22	Intendis GmbH	Process for the manufacture of non-steroidal anti-inflammatory agents and intermediates thereof
KR20090129480A (ko) *	2007-04-18	2009-12-16	인텐디스 게엠베하	비스테로이드성 항염증제의 제조 방법 및 그의 중간체
EP2016935A1 (en) *	2007-07-09	2009-01-21	Intendis GmbH	Pharmaceutical composition for topical application of poorly soluble compounds
US20090042936A1 (en) *	2007-08-10	2009-02-12	Ward Keith W	Compositions and Methods for Treating or Controlling Anterior-Segment Inflammation
US20090087443A1 (en) *	2007-09-27	2009-04-02	Bartels Stephen P	Pharmacological Adjunctive Treatment Associated with Glaucoma Filtration Surgery
CA2702761A1 (en) *	2007-11-01	2009-05-07	Bausch & Lomb Incorporated	Non-aqueous water-miscible materials as vehicles for drug delivery
US20110077270A1 (en) *	2009-04-21	2011-03-31	Pfeffer Bruce A	Compositions and Methods for Treating Ocular Inflammation with Lower Risk of Increased Intraocular Pressure
CN101983961B (zh) *	2010-11-24	2012-05-09	浙江启明生化科技有限公司	5-氨基-2-甲基喹啉的制备方法
US20120316199A1 (en)	2011-06-07	2012-12-13	Ward Keith W	Compositions and methods for treating, controlling, reducing, or ameliorating inflammatory pain
WO2017137375A1 (en)	2016-02-12	2017-08-17	Bayer Animal Health Gmbh	Mapracorat for use in the treatment of canine dermatitis
CN111646908B (zh) *	2017-01-16	2023-03-10	宜昌尚诺德生物医药科技有限公司	一种制备芳胺化合物的方法
CA3123490A1 (en)	2019-01-22	2020-07-30	Akribes Biomedical Gmbh	Selective glucocorticoid receptor modifiers for treating impaired skin wound healing

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4041482A1 (de) *	1990-12-22	1992-06-25	Boehringer Ingelheim Kg	Neue pharmazeutische verwendung carbocyclisch und heterocyclisch annelierter dihydropyridine
NO940245D0 (no) *	1993-01-28	1994-01-24	Takeda Chemical Industries Ltd	Quinolin eller quinazolinderivater, deres fremstilling og anvendelse
RU2127271C1 (ru) *	1997-03-13	1999-03-10	Пермская государственная фармацевтическая академия	5-нитрофурфурилиденгидразид 2-хлор-5,6,7,8,-тетрагидрохинолин-4-карбоновой кислоты, обладающий антимикробной активностью
UA73492C2 (en) *	1999-01-19	2005-08-15		Aromatic heterocyclic compounds as antiinflammatory agents
DE10215316C1 (de) *	2002-04-02	2003-12-18	Schering Ag	Chinolin- und Isochinolin-Derivate, ein pharmazeutisches Mittel und ihre Verwendung als Entzündungshemmer
CA2512257A1 (en) *	2003-01-03	2004-07-29	Boehringer Ingelheim Pharmaceuticals, Inc.	1-propanol and 1-propylamine derivatives and their use as glucocorticoid ligands
US20040224992A1 (en) *	2003-02-27	2004-11-11	Boehringer Ingelheim Pharmaceuticals, Inc.	Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US7179919B2 (en) *	2004-03-18	2007-02-20	Boehringer Ingelheim Pharmaceuticals, Inc.	Stereoselective synthesis of certain trifluoromethyl-substituted alcohols

2004
- 2004-11-12 DE DE102004055633A patent/DE102004055633A1/de not_active Ceased
2005
- 2005-11-11 DK DK05808294T patent/DK1844039T3/da active
- 2005-11-11 TW TW094139706A patent/TWI311559B/zh not_active IP Right Cessation
- 2005-11-11 CN CN2005800464522A patent/CN101124220B/zh not_active Expired - Fee Related
- 2005-11-11 GT GT200500330A patent/GT200500330A/es unknown
- 2005-11-11 SI SI200530792T patent/SI1844039T1/sl unknown
- 2005-11-11 RS RSP-2009/0367A patent/RS51161B/sr unknown
- 2005-11-11 ME MEP-136/08A patent/MEP13608A/xx unknown
- 2005-11-11 NZ NZ555064A patent/NZ555064A/en not_active IP Right Cessation
- 2005-11-11 PT PT05808294T patent/PT1844039E/pt unknown
- 2005-11-11 MY MYPI20055308A patent/MY141780A/en unknown
- 2005-11-11 JP JP2007540615A patent/JP4460608B2/ja not_active Expired - Fee Related
- 2005-11-11 EP EP05808294A patent/EP1844039B1/de not_active Expired - Lifetime
- 2005-11-11 AU AU2005303926A patent/AU2005303926B2/en not_active Ceased
- 2005-11-11 DE DE502005007725T patent/DE502005007725D1/de not_active Expired - Lifetime
- 2005-11-11 PL PL05808294T patent/PL1844039T3/pl unknown
- 2005-11-11 WO PCT/EP2005/012531 patent/WO2006050998A1/de not_active Ceased
- 2005-11-11 CA CA2586689A patent/CA2586689C/en not_active Expired - Fee Related
- 2005-11-11 ME MEP-2008-136A patent/ME00155B/me unknown
- 2005-11-11 BR BRPI0517797-9A patent/BRPI0517797A/pt not_active IP Right Cessation
- 2005-11-11 MX MX2007005736A patent/MX2007005736A/es active IP Right Grant
- 2005-11-11 HR HR20090509T patent/HRP20090509T1/hr unknown
- 2005-11-11 ES ES05808294T patent/ES2329599T3/es not_active Expired - Lifetime
- 2005-11-11 RS RSP-2007/0205A patent/RS20070205A/sr unknown
- 2005-11-11 KR KR1020077010785A patent/KR101168462B1/ko not_active Expired - Fee Related
- 2005-11-11 EA EA200700982A patent/EA013076B1/ru not_active IP Right Cessation
- 2005-11-14 UY UY29213A patent/UY29213A1/es not_active Application Discontinuation
- 2005-11-14 PA PA20058652701A patent/PA8652701A1/es unknown
- 2005-11-14 AR ARP050104767A patent/AR051767A1/es not_active Application Discontinuation
- 2005-11-14 PE PE2005001324A patent/PE20061052A1/es not_active Application Discontinuation
2007
- 2007-05-02 IL IL182933A patent/IL182933A/en not_active IP Right Cessation
- 2007-06-11 NO NO20072963A patent/NO332405B1/no not_active IP Right Cessation
2009
- 2009-10-15 CY CY20091101074T patent/CY1110520T1/el unknown

Also Published As

Publication number	Publication date
MY141780A (en)	2010-06-30
MX2007005736A (es)	2007-09-07
WO2006050998A1 (de)	2006-05-18
CN101124220A (zh)	2008-02-13
RS20070205A (sr)	2008-11-28
EA200700982A1 (ru)	2007-10-26
TW200640913A (en)	2006-12-01
KR20070084192A (ko)	2007-08-24
EP1844039A1 (de)	2007-10-17
AU2005303926B2 (en)	2011-05-19
PL1844039T3 (pl)	2009-12-31
AR051767A1 (es)	2007-02-07
BRPI0517797A (pt)	2008-10-21
PE20061052A1 (es)	2006-11-08
RS51161B (sr)	2010-10-31
CY1110520T1 (el)	2015-04-29
EA013076B1 (ru)	2010-02-26
EP1844039B1 (de)	2009-07-15
MEP13608A (en)	2010-06-10
HRP20090509T1 (hr)	2009-11-30
PT1844039E (pt)	2009-10-19
GT200500330A (es)	2006-09-21
DE102004055633A1 (de)	2006-05-18
DE502005007725D1 (de)	2009-08-27
IL182933A (en)	2011-10-31
NZ555064A (en)	2009-09-25
SI1844039T1 (sl)	2009-12-31
NO20072963L (no)	2007-08-03
CA2586689A1 (en)	2006-05-18
IL182933A0 (en)	2007-09-20
ME00155B (me)	2010-10-10
JP4460608B2 (ja)	2010-05-12
HK1112243A1 (en)	2008-08-29
AU2005303926A1 (en)	2006-05-18
ES2329599T3 (es)	2009-11-27
JP2008519803A (ja)	2008-06-12
DK1844039T3 (da)	2009-11-09
CA2586689C (en)	2012-04-17
KR101168462B1 (ko)	2012-07-27
CN101124220B (zh)	2012-04-25
TWI311559B (en)	2009-07-01
UY29213A1 (es)	2006-05-31
PA8652701A1 (es)	2006-07-03

Legal Events

Date	Code	Title	Description
2015-06-22	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
NO332405B1 (no)	2012-09-10	Forbindelse av 5-substituerte kinolin- og isokinolinderivater, fremgangsmate for deres fremstilling, deres anvendelse til fremstilling av farmasoytiske midler for behandling av inflammatorisk sykdom og farmasoytisk preparat omfattende forbindelsen.
NO340679B1 (no)	2017-05-29	Pyridazinonderivativer, farmasøytiske preparater omfattende slike og slike forbindelser og preparater for anvendelse i terapeutisk aktive substanser til behandling og forebygging av sykdommer
DK1620429T3 (da)	2009-05-18	Nye heterocykliske forbindelser anvendelige til behandling af inflammatoriske og allergiske sygdomme, fremgangsmåder til deres fremstilling og farmaceutiske sammensætninger indeholdende disse
BRPI0806531A2 (pt)	2014-04-22	Composto, composição farmacêutica, agente terapêutico, e, uso do composto.
NO20053920D0 (no)	2005-08-23	Preparat for og behandling av demyelineringssykdommer og paralyse ved administrering av remyelineringsmidler.
DK1761266T3 (da)	2013-08-05	Forbindelser, formuleringer og fremgangsmåder til at behandle eller forebygge inflammatoriske hudsygdomme
IL191984A0 (en)	2008-12-29	Isoquinoline aminopyrazole derivatives, their manufacture and use as pharmaceutical agents for the treatment of cancer
NO2012017I1 (no)	2012-11-26	Benzimidazolderivat, fremgangsmåte for fremstilling derav, medikament inneholdende denne forbindelsen samt anvendelse av forbindelsen.
DK1853271T3 (da)	2011-01-24	Fremgangsmåde og præparat til behandling af perifere vaskulære sygdomme
CL2007003265A1 (es)	2008-06-06	Compuestos derivados de 1h-piran[2,3-d]pirimidin-2,4,7-triona; y composicion farmaceutica, util para el tratamiento de sindrome metabolico, dislipidemia y enfermedades cardiovasculares entre otras.
DK2069342T3 (da)	2010-08-23	Derivater af 2-aryl-6-phenyl-imidazol[1,2-A]pyridiner, fremstilling og terapeutisk anvendelse deraf
NO20055496L (no)	2006-02-14	Pyrazolokinazolinderivater, metoder for deres fremstilling og deres anvendelse som kinaseinhibitorer
WO2007038459A3 (en)	2007-07-12	Carboxyamine compounds and their use in the treatment of hdac dependent diseases
NL1025073C2 (nl)	2005-02-01	Indazoolverbindingen en farmaceutische preparaten voor het remmen van proteïnekinasen, en werkwijzen voor hun gebruik.
NO20055686L (no)	2007-06-04	Sammensetning, fremgangsmate til fremstilling derav, og anvendelse derav.
CL2007003690A1 (es)	2008-08-22	Compuestos derivados de 1-azonia-biciclo[2.2.2]octano; proceso de preparacion; composicion farmaceutica; y uso en el tratamiento de enfermedades pulmonares obstructivas cronicas.
WO2008076954A3 (en)	2008-09-18	Heterocycle compounds and methods of use thereof
CL2007003038A1 (es)	2008-06-06	Compuestos derivados de 2-fenil-6-aminocarbonil-pirimidina; composicion farmaceutica; y uso en el tratamiento de trastornos vasculares oclusivos.
DK1939204T3 (da)	2013-03-11	Kondenseret heterocyklisk derivat, medicinalsammensætning indeholdende samme og medicinsk anvendelse deraf
DE602007011398D1 (de)	2011-02-03	Trialkylsilylbenzylaminocarboxyindole, indazole und indoline und ihre verwendung zur behandlung von cetp-vermittelten erkrankungen
DK1922309T3 (da)	2014-08-25	N-phenyl-2-pyrimidin-aminderivater og fremgangsmåde til fremstillingen deraf
NO20070892L (no)	2007-04-11	Sammensetninger av N-glykolylneuraminsyre og anvendelse derav ved behandling av forkjølelse.
PL2059503T3 (pl)	2016-01-29	Pochodne aminopirazolu, sposób ich wytwarzania oraz kompozycja do zapobiegania lub leczenia chorób niedokrwiennych zawierająca takie pochodne
NO20052262D0 (no)	2005-05-06	Fremgangsmate til fremstilling av 4-substituerte 2,2,6,6-tetrametyl-piperidin-N-oksy- og 2,2,6,6-tetrametyl-piperidin-N-hydroksy-forbindelser
NO20053348D0 (no)	2005-07-11	Farmasoytisk sammensetning for behandling av virusangrep.